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Studies on DSB ends which are strongly relevant to the biological effects of ion particles

Research Project

Project/Area Number 16H02959
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Risk sciences of radiation and chemicals
Research InstitutionNational Institutes for Quantum and Radiological Science and Technology

Principal Investigator

Shikazono Naoya  国立研究開発法人量子科学技術研究開発機構, 量子生命科学領域, 統括グループリーダー(定常) (10354961)

Co-Investigator(Kenkyū-buntansha) 佐藤 達彦  国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門 原子力科学研究所 原子力基礎工学研究センター, 研究主席 (30354707)
森林 健悟  国立研究開発法人量子科学技術研究開発機構, 量子生命科学領域, 上席研究員(定常) (70354975)
赤松 憲  国立研究開発法人量子科学技術研究開発機構, 量子生命科学領域, グループリーダー(定常) (70360401)
甲斐 健師  国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門 原子力科学研究所 原子力基礎工学研究センター, 研究主幹 (70403037)
Project Period (FY) 2016-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2019: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2018: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
KeywordsDNA損傷 / 局在性 / イオンビーム / シミュレーション / FRET / 原子間力顕微鏡 / 二本鎖切断末端 / エネルギー付与 / 放射線 / 二本鎖切断
Outline of Final Research Achievements

In order to deepen the understanding of the biological effects of ion particles, we focused on the localization of DNA damage, especially at DSB ends. The dose distribution calculation code was further improved to obtain information on precise positions of ionizations and excitations, and the location of damage induced in DNA was simulated. In addition, the localization of ion beam-induced DNA damage was clarified experimentally by the novel methods based on fluorescence resonance energy transfer and single-molecule observation with an atomic force microscope. From these studies, we gained valuable insights on the mechanism of biological effects of ion particles.

Academic Significance and Societal Importance of the Research Achievements

エネルギー付与からDNA損傷の修復までの過程を統一的に取り扱い、イオンビーム生物影響メカニズム解明のための第一歩となる成果を得た。革新的なシミュレーション、及び、新たな実験法の開発によって得られた本研究成果は、これまでブラックボックスであったイオンビームによるエネルギー付与と生物影響の関係を解明する基盤となるものであり、関連分野でのインパクトが極めて大きい。今後本研究で得られた成果を基盤に研究を進展させることにより、イオンビーム生物影響の理解が大いに進むと考えられる。

Report

(6 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (63 results)

All 2021 2020 2019 2018 2017 2016

All Journal Article (22 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 19 results,  Open Access: 8 results,  Acknowledgement Compliant: 4 results) Presentation (40 results) (of which Int'l Joint Research: 11 results,  Invited: 6 results) Book (1 results)

  • [Journal Article] Fluorescence anisotropy study of radiation-induced DNA damage clustering based on FRET2021

    • Author(s)
      Akamatsu Ken、Shikazono Naoya、Saito Takeshi
    • Journal Title

      Analytical and Bioanalytical Chemistry

      Volume: 413 Issue: 4 Pages: 1185-1192

    • DOI

      10.1007/s00216-020-03082-w

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Debye shield formed by track potential and transport of secondary electrons in heavy ion irradiation2021

    • Author(s)
      Kengo Moribayashi
    • Journal Title

      Radiation Physics and Chemistry

      Volume: 184 Pages: 109436-109436

    • DOI

      10.1016/j.radphyschem.2021.109436

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of gamma irradiation-induced mutations in Arabidopsis mutants deficient in non-homologous end joining2020

    • Author(s)
      Du Yan、Hase Yoshihiro、Satoh Katsuya、Shikazono Naoya
    • Journal Title

      Journal of Radiation Research

      Volume: 61 Issue: 5 Pages: 639-647

    • DOI

      10.1093/jrr/rraa059

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Strand with mutagenic lesion is preferentially used as a template in the region of a bi-stranded clustered DNA damage site in Escherichia coli2020

    • Author(s)
      Shikazono Naoya、Akamatsu Ken
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 9737-9737

    • DOI

      10.1038/s41598-020-66651-0

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relation between biomolecular dissociation and energy of secondary electrons generated in liquid water by fast heavy ions2020

    • Author(s)
      Tsuchida Hidetsugu、Kai Takeshi、Kitajima Kensei、Matsuya Yusuke、Majima Takuya、Saito Manabu
    • Journal Title

      The European Physical Journal D

      Volume: 74 Issue: 10 Pages: 212-212

    • DOI

      10.1140/epjd/e2020-10172-x

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Simplified Cluster Analysis of Electron Track Structure for Estimating Complex DNA Damage Yields2020

    • Author(s)
      Matsuya, Y., Nakano, T., Kai, T., Shikazono, N., Akamatsu, K., Yoshii, Y, Sato, T.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 5 Pages: 1-13

    • DOI

      10.3390/ijms21051701

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Application of simple formulas to track potential in heavy-ion-beam simulation2018

    • Author(s)
      K. Moribayashi
    • Journal Title

      Transactions of the Materials Research Society of Japan

      Volume: 43 Issue: 5 Pages: 267-270

    • DOI

      10.14723/tmrsj.43.267

    • NAID

      130007493491

    • ISSN
      1382-3469, 2188-1650
    • Year and Date
      2018-10-01
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mutagenic potential of 8-oxo-7,8-dihydroguanine (8-oxoG) is influenced by nearby clustered lesions2018

    • Author(s)
      Shikazono Naoya、Akamatsu Ken
    • Journal Title

      Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

      Volume: 810 Pages: 6-12

    • DOI

      10.1016/j.mrfmmm.2018.05.001

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 放射線物理化学過程に関する最近の進展(後編)2018

    • Author(s)
      甲斐健師、横谷明徳、藤井健太郎、渡邊立子
    • Journal Title

      放射線化学

      Volume: 106 Pages: 21-29

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the track potential on the motion and energy flow of secondary electrons created from heavy-ion irradiation2018

    • Author(s)
      K. Moribayashi
    • Journal Title

      Radiate. Phys. Chem.

      Volume: 146 Pages: 68-72

    • DOI

      10.1016/j.radphyschem.2018.01.017

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Proposal for Experiment Systems Using Laser Driven Heavy Ions and XFELs to Understand Physical Phenomena Occurring near the Incident Ion Path2018

    • Author(s)
      K. Moribayashi
    • Journal Title

      Proc. 15th Int. Conf. X-ray lasers

      Volume: 292 Pages: 121-123

    • DOI

      10.1007/978-3-319-73025-7_19

    • ISBN
      9783319730240, 9783319730257
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A significant role of non-thermal equilibrated electrons in the formation of deleterious complex DNA damage2018

    • Author(s)
      Takeshi Kai, Akinari Yokoya, Masatoshi Ukai, Kentaro Fujii, Tomohiro Toigawa, Rituko Watanabe
    • Journal Title

      Physical Chemistry Chemical Physics

      Volume: 92 Issue: 4 Pages: 660-664

    • DOI

      10.1039/c7cp06903k

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Features of Particle and Heavy Ion Transport code System (PHITS) version 3.022018

    • Author(s)
      Sato Tatsuhiko、Iwamoto Yosuke、Hashimoto Shintaro、Ogawa Tatsuhiko、Furuta Takuya、Abe Shin-ichiro、Kai Takeshi、Tsai Pi-En、Matsuda Norihiro、Iwase Hiroshi、Shigyo Nobuhiro、Sihver Lembit、Niita Koji
    • Journal Title

      Journal of Nuclear Science and Technology

      Volume: 55 Issue: 6 Pages: 684-690

    • DOI

      10.1080/00223131.2017.1419890

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] New method for estimating clustering of DNA lesions induced by physical/chemical mutagens using fluorescence anisotropy2017

    • Author(s)
      K. Akamatsu, N. Shikazono, and T. Saito
    • Journal Title

      Analytical Biochemistry

      Volume: 536 Pages: 78-89

    • DOI

      10.1016/j.ab.2017.08.007

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Radiation-induced clustered DNA lesions: Repair and mutagenesis2017

    • Author(s)
      E. Sage and N. Shikazono
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 印刷中 Pages: 125-135

    • DOI

      10.1016/j.freeradbiomed.2016.12.008

    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] 高エネルギー電子衝突により水中で生成された2次電子の動的挙動2017

    • Author(s)
      甲斐健師、横谷明徳、藤井健太郎、渡邊立子
    • Journal Title

      陽電子科学

      Volume: 8 Pages: 11-17

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Effect of track potentials on the movement of secondary electrons due to irradiation of heavy ions2017

    • Author(s)
      K. Moribayashi
    • Journal Title

      J. Phys. Soc. Jpn

      Volume: 86 Issue: 2 Pages: 024301-024301

    • DOI

      10.7566/jpsj.86.024301

    • NAID

      40021098389

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficiency of radiation-induced base lesion excision and the order of enzymatic treatment2016

    • Author(s)
      Shiraishi, I., Shikazono, N., Fujii, K. and Yokoya, A.
    • Journal Title

      Int. J. Radiat. Biol.

      Volume: 93 Issue: 3 Pages: 295-302

    • DOI

      10.1080/09553002.2017.1239849

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Dynamic Behavior of Secondary Electrons in Liquid Water at the Earliest Stage upon Irradiation: Implications for DNA Damage Localization Mechanism2016

    • Author(s)
      Kai, T., Yokoya, A., Ukai, M., Fujii, K. and Watanabe, R.
    • Journal Title

      J. Phys. Chem. A

      Volume: 120 Issue: 42 Pages: 8228-8233

    • DOI

      10.1021/acs.jpca.6b05929

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Deceleration processes of secondary electrons produced by a high-energy Auger electron in a biological context2016

    • Author(s)
      Takeshi Kai, Akinari Yokoya, Masatoshi Ukai, Kentaro Fujii, and Ritsuko Watanabe
    • Journal Title

      Int. J. Radiat. Biol.

      Volume: 92 Issue: 11 Pages: 654-659

    • DOI

      10.1080/09553002.2016.1195933

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 放射線物理化学過程に関する最近の進展(前編)2016

    • Author(s)
      甲斐健師、横谷明徳、藤井健太郎、渡邊立子
    • Journal Title

      放射線化学

      Volume: 101 Pages: 3-11

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 放射線物理化学過程に関する最近の進展(中編)2016

    • Author(s)
      甲斐健師、横谷明徳、藤井健太郎、渡邊立子
    • Journal Title

      放射線化学

      Volume: 102 Pages: 49-56

    • Related Report
      2016 Annual Research Report
  • [Presentation] 重イオンビーム照射におけるデバイ遮蔽の生成過程2021

    • Author(s)
      森林健悟
    • Organizer
      日本物理学会第76回年次大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 放射線誘発クラスターDNA損傷の直接観察とその修復2020

    • Author(s)
      鹿園直哉、赤松憲、中野敏彰
    • Organizer
      日本放射線影響学会第63回大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] FRET analyses of DNA damage clustering in plasmid DNA irradiated under a cell-mimetic condition2020

    • Author(s)
      Ken Akamatsu, Naoya Shikazono
    • Organizer
      日本放射線影響学会第63回大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Involvement of SPRTN in DNA protein cross-link damage repair2020

    • Author(s)
      T. Nakano, H. Sasanuma, M. Tuda, K. Hirota, N. Shikazono, M. Kawanishi, S. Takeda, H. Ide, K. Tano
    • Organizer
      第43回日本分子生物学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 磁場がイオンビームの生物効果を増大させる理由の検討:熱膨張仮説2020

    • Author(s)
      森林健悟
    • Organizer
      量子生命科学会第2回大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Plasma formed by track potential and transport of secondary electrons in heavy ion irradiation on surfaces2020

    • Author(s)
      Kengo Moribayashi
    • Organizer
      第21回「イオンビームによる表面・界面の解析と改質」特別研究会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 重粒子線がん治療における原子分子・プラズマ物理の役割2020

    • Author(s)
      森林健悟
    • Organizer
      第45回原子衝突学会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Template strand preference for replication at regions surrounding a clustered DNA damage site in Escherichia coli2019

    • Author(s)
      Naoya Shikazono, Ken Akamatsu
    • Organizer
      16th International Congress of Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Study of radiation-induced clustered DNA damage by fluorescence anisotropy measurement based on Forster resonance energy transfer2019

    • Author(s)
      Ken Akamatsu, Naoya Shikazono
    • Organizer
      16th International Congress of Radiation Research
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] クラスターDNA損傷形態の線質依存性2019

    • Author(s)
      赤松憲、鹿園直哉
    • Organizer
      第62回日本放射線影響学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 重イオンビームの新規動径線量シミュレーションモデル:従来のモデルとの比較2019

    • Author(s)
      森林健悟
    • Organizer
      日本物理学会2019秋季大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Application of nano-sized low-temperature plasma produced from heavy ion irradiation to heavy ion cancer therapy2019

    • Author(s)
      Kengo Moribayashi
    • Organizer
      XXXIV International Conference on Phenomena in Ionized Gases and 10th International Conference on Reactive Plasmas
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Application of atomic and molecular data to heavy ion beam plasma production and further, heavy ion beam cancer therapy2019

    • Author(s)
      Kengo Moribayashi
    • Organizer
      International Workshop on Atomic and Molecular Data for Plasma Applications
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 重イオンビーム照射におけるブラッグピーク付近での温度上昇2019

    • Author(s)
      森林健悟
    • Organizer
      日本物理学会第74回年次大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] PHITSにおけるイオンの飛跡構造計算機能の開発2019

    • Author(s)
      甲斐健師、佐藤達彦、Thiansin Liamsuwan、Hooshang Nikjoo
    • Organizer
      第66回応用物理学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 最先端の物理的・化学的手法から探る凝縮相の放射線分解・反応ダイナミクス2019

    • Author(s)
      甲斐健師
    • Organizer
      日本物理学会第74回年次大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Measurement and mutagenic potential of clustered DNA lesions2018

    • Author(s)
      Naoya Shikazono, Ken Akamatsu
    • Organizer
      15th International Workshop on Radiation Damage to DNA
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Biological effects of ionizing radiation and clustered DNA damage2018

    • Author(s)
      Naoya Shikazono
    • Organizer
      Radiation biology symposium
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] ホモFRETを利用したクラスターDNA損傷形態の線質依存性2018

    • Author(s)
      赤松憲、鹿園直哉
    • Organizer
      第61回日本放射線影響学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 重粒子線によって生じる難修復性複雑DNA損傷の構造的特徴2018

    • Author(s)
      赤松憲
    • Organizer
      原子衝突学会第43回年会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 重イオンビーム照射によって生じる熱膨張が引き起こすDNA損傷の可能性2018

    • Author(s)
      森林健悟
    • Organizer
      原子衝突学会第43回年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Role of ion impact ionization cross sections in radiation biology using swift highly charged ion beams2018

    • Author(s)
      Kengo Moribayashi
    • Organizer
      19th International Conference: Physics of Highly Charged Ion
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 水の放射線分解で誘発された低エネルギー電子の動的挙動解析2018

    • Author(s)
      甲斐健師、米谷 佳晃
    • Organizer
      日本物理学会2018年秋季大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] XFELを用いた高強度レーザー駆動重イオン照射の物理現象の観測法の提案2018

    • Author(s)
      森林健悟
    • Organizer
      日本物理学会第73回年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 凝縮相における低エネルギー電子の微視的放射線作用の研究 ― 電子輸送計算法の開発 ―2017

    • Author(s)
      甲斐健師、小川達彦、安部晋一郎、佐藤達彦
    • Organizer
      第64回応用物理学会
    • Place of Presentation
      パシフィコ横浜(横浜市、神奈川県)
    • Year and Date
      2017-03-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] 動的モンテカルロ法を用いた凝縮相における低速電子の微視的挙動2017

    • Author(s)
      甲斐健師
    • Organizer
      第31回固体飛跡検出器研究会
    • Place of Presentation
      量子科学技術研究開発機構(木津川市、京都府)
    • Year and Date
      2017-03-09
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高強度場科学の分野からの重イオンビーム科学研究へのアプローチ2017

    • Author(s)
      森林健悟
    • Organizer
      レーザー学会学術講演会第37回年次大会
    • Place of Presentation
      徳島大学(徳島市、徳島県)
    • Year and Date
      2017-01-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] Detection and mutagenic potential of clustered DNA lesions2017

    • Author(s)
      N. Shikazono, K. Akamatsu
    • Organizer
      17th International Symposium on Microdosimetry
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 電離放射線によって生じたDNA損傷の局在性について フェルスター共鳴エネルギー移動(FRET)を用いたアプローチ2017

    • Author(s)
      赤松憲、鹿園直哉
    • Organizer
      第60回日本放射線影響学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 各種DNA損傷因子によって生じたクラスターDNA損傷のキャラクタリゼーション2017

    • Author(s)
      赤松憲、鹿園直哉
    • Organizer
      第60回日本放射線影響学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 重イオンの軌道付近で生成する ナノプラズマ中の電子の総エネルギー2017

    • Author(s)
      森林健悟
    • Organizer
      日本物理学会2017年秋季大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 重イオンビーム照射によるナノプラズマ生成シミュレーション2017

    • Author(s)
      森林健悟
    • Organizer
      原子衝突学会第42回年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Role of ion impact ionization cross sections in the irradiation of swift heavy ions into condensed matter2017

    • Author(s)
      K. Moribayashi
    • Organizer
      The 30th International Conference on Photonic, Electronic and Atomic Collisions
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Application of stochastic microdosimetric kinetic model to boron neutron capture therapy2017

    • Author(s)
      T. Sato, S. Masunaga, H. Kumada, N. Hamada
    • Organizer
      17th International Symposium on Microdosimetry
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 重イオンビームが生成するナノメータサイズプラズマの粒子シミュレーション2016

    • Author(s)
      森林健悟
    • Organizer
      プラズマ科学における分光計測の高度化と原子分子過程研究の新展開研究会
    • Place of Presentation
      核融合研究所(土岐市、岐阜県)
    • Year and Date
      2016-12-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] クラスターDNA損傷及びミスマッチを有するプラスミドの作製法の開発2016

    • Author(s)
      高橋桃子、赤松憲、鹿園直哉
    • Organizer
      第59回日本放射線影響学会
    • Place of Presentation
      JMSアステールプラザ(広島市、広島県)
    • Year and Date
      2016-10-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] 蛍光異方性を利用した放射線DNA損傷の局在性評価法の開発―細胞核内クラスター損傷の観察に向けた基礎検討―2016

    • Author(s)
      赤松憲、鹿園直哉
    • Organizer
      第59回日本放射線影響学会
    • Place of Presentation
      JMSアステールプラザ(広島市、広島県)
    • Year and Date
      2016-10-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] 電子線トラックエンドの放射線最初期過程の研究2016

    • Author(s)
      甲斐健師、横谷明徳、鵜飼正敏、藤井健太郎、渡邊立子、米谷佳晃、樋川智洋、佐藤達彦
    • Organizer
      第59回放射線化学討論会
    • Place of Presentation
      量子科学技術研究開発機構(高崎市、群馬県)
    • Year and Date
      2016-09-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Simulation study for the effect of track potentials on the movement of secondary electrons due to highly charged ion irradiation2016

    • Author(s)
      K. Moribayashi
    • Organizer
      18th international conference; physics of highly charged ions
    • Place of Presentation
      Jan Kochanowski University(Kielce、ポーランド)
    • Year and Date
      2016-09-11
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Aiming to measure cluster DNA damage, proposal for experiment systems using XFEL and laser driven ion beams2016

    • Author(s)
      K. Moribayashi
    • Organizer
      The 15th International Conference on X-Ray Lasers
    • Place of Presentation
      Nara Kasugano International Forum(奈良市、奈良県)
    • Year and Date
      2016-05-22
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Book] Application of laser-driven particle acceleration, Chapter 10, Using laser-driven ion sources to study fast radiobiological processes2018

    • Author(s)
      N. Shiakazono, K. Moribayashi, P.R. Bolton
    • Total Pages
      14
    • Publisher
      CRC press Taylor & Francis group
    • Related Report
      2018 Annual Research Report

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Published: 2016-04-21   Modified: 2022-01-27  

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