| Budget Amount *help |
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2019: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2018: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2017: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
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| Outline of Final Research Achievements |
In this project, we found that daily consumption of flavonoids increases their absorption rate, and also one of major functions is the effect of lipid metabolism. Therefore, we employed quercetin as candidate flavonoids, and evaluated it’s mother-infant interaction. Consequently, we obtained the following aspects: 1) hepatic triglyceride levels were significantly decreased in the infants from the mother consuming quercetin during the pregnancy, and this effect was remarkable in the groups consuming high-fat diet; 2) mice from mother consumed quercetin were sensitive for high-fat induced overweight comparing with mice from mother not consumed quercetin. In conclusion, our results clearly indicate the importance for mother-infant interaction of functions existed in dietary flavonoids.
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