Analysis of the occurrence factor in eating-experience induced modification of taste palatability and its effect on eating behavior
Project/Area Number |
16H03045
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Eating habits
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Research Institution | The University of Tokyo |
Principal Investigator |
Narukawa Masataka 東京大学, 大学院農学生命科学研究科(農学部), 特任助教 (50432349)
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Project Period (FY) |
2016-04-01 – 2019-03-31
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Project Status |
Completed (Fiscal Year 2018)
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Budget Amount *help |
¥16,380,000 (Direct Cost: ¥12,600,000、Indirect Cost: ¥3,780,000)
Fiscal Year 2018: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2016: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
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Keywords | 味 / 食経験 / 嗜好性 / 味嗜好性 / 摂食行動 |
Outline of Final Research Achievements |
The palatability of the food is known to be affected by various factors, such as environment and experience. However, the underlying mechanisms are still unknown. This study was aimed to elucidate the mechanism that mediates the taste palatability modification by eating experience. In addition, we investigated the effect of this modification on eating behaviors. We found that the hypothalamus and amygdala regions are related to the modification of taste palatability by eating experience, and that this modification might affect the food choice.
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Academic Significance and Societal Importance of the Research Achievements |
食に対する嗜好性は様々な要因によって変化する。しかし、その分子機構は不明である。本研究では食経験に伴う嗜好性の変化に中枢の視床下部や扁桃体が関与している可能性を示した。さらに、食経験が食選択にも影響を及ぼす可能性を見出した。嗜好性の変化を生じるような神経回路を明らかにすることは摂食を抑制・促進するような食品の開発に繋がると期待される。本研究で得られた成果は健康的な食生活を送るための有用な知見になると期待される。
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Report
(4 results)
Research Products
(38 results)
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[Journal Article] Novel indole and benzothiophene ring derivatives showing differential modulatory activity against human epithelial sodium channel subunits, ENaC β and γ2019
Author(s)
Kasahara Y, Sakurai T, Matsuda R, Narukawa M, Yasuoka A, Mori N, Watanabe H, Okabe T, Kojima H, Abe K, Misaka T, and Asakura T
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Journal Title
Bioscience, Biotechnology, and Biochemistry
Volume: 83
Issue: 2
Pages: 243-250
DOI
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Peer Reviewed / Open Access
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[Journal Article] Catecholamines facilitate fuel expenditure and protect against obesity via a novel network of the gut-brain axis in transcription factor Skn-1-deficient mice.2016
Author(s)
Ushiama, S., Ishimaru, Y., Narukawa, M., Yoshioka, M., Kozuka, C., Watanabe, N., Tsunoda, M., Osakabe, N., Asakura, T., Masuzaki, H., and Abe, K.
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Journal Title
EBioMedicine
Volume: 8
Pages: 60-71
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Presentation] Catecholamines facilitate fuel expenditure and protect against obesity via a novel network of the gut-brain axis in transcription factor Skn-1 -deficient mice2016
Author(s)
Ishimaru Y, Ushiama S, Narukawa M, Yoshioka M, Kozuka C, Watanabe N, Tsunoda M, Osakabe N, Asakura T, Masuzaki H, and Abe K
Organizer
International Symposium of Olfactory and Taste 2017
Place of Presentation
パシフィコ横浜(神奈川県横浜市)
Year and Date
2016-06-05
Related Report
Int'l Joint Research
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