| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000)
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| Outline of Final Research Achievements |
We studied competition of two neutral populations of bacteria cultured in a microfluidic device and characterized its spatiotemporal dynamics from the viewpoint of statistical physics. First we developed a novel, perfusion-type microfluidic device, which allows for long time-lapsed observation of dense bacterial populations under spatially uniform conditions. Using this device, we cultured two strains of Escherichia coli labeled with fluorescent proteins, and found formation of fractal patterns in the regions occupied by the two strains. Analyzing its statistical properties and the nematic order, we proposed a prospective role of topological defects in this problem. We also proposed a theoretical model for bacterial competition. Simulations and theoretical analysis of this model revealed relationship to the voter universality class in non-equilibrium statistical physics.
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