| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2017: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
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| Outline of Final Research Achievements |
In this study, we tried to experimentally grasp the factors that controls the robustness of the in vivo reaction at non-equilibrium interface, from a comparison with equilibrium systems. Using gel thin films and self-assembled films as model systems, we developed experimental and theoretical studies to distinguish features such as order formation, self-assembly, and self-repair at interfaces with different non-equilibrium properties. We obtained fundamental findings that elucidate the importance of non-equilibrium system in biological interface from thermodynamic features that govern the selection rule of pattern formation in nature. Also, We obtained applicational findings that provide molecular design from a non-equilibrium point of view regarding pharmacological activity on biological membranes.
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