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Synthesis of novel porous spherical particles using spontaneous micro-spheronization phenomenon and application to sustained release carrier

Research Project

Project/Area Number 16H04212
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Inorganic industrial materials
Research InstitutionUniversity of Tsukuba

Principal Investigator

Suzuki Yoshikazu  筑波大学, 数理物質系, 准教授 (40357281)

Co-Investigator(Kenkyū-buntansha) 鈴木 達  国立研究開発法人物質・材料研究機構, 機能性材料研究拠点, グループリーダー (50267407)
阿部 浩也  大阪大学, 接合科学研究所, 准教授 (50346136)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2019: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2018: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2017: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Keywords自発的マイクロ球体化 / 多孔質球状顆粒 / 高温その場観察 / 微構造チューニング / スーパーキャパシタ材料 / 多孔質球状粒子 / マイクロ球体化現象 / スーパーキャパシタ / 水熱合成 / ウニ状マイクロ粒子 / サイズ制御 / 階層構造 / 徐放性キャリア / 三次元ネットワーク多孔体 / 擬ブルッカイト / ブルッカイト / スピネル / 三次元ネットワーク構造 / 共焦点レーザー顕微鏡 / 画像解析 / 三次元ネットワーク型多孔体
Outline of Final Research Achievements

In this study, regarding novel porous spherical particles by spontaneous microsphere formation phenomenon, (1) elucidation of generation mechanism, (2) fine structure tuning and functionalization, (3) application development to sustained release carrier. By the spontaneous micro-spheronization method, the inorganic mixed powders were made into porous spherical granules with uniform open pores and excellent handling, only by heating in an atmospheric furnace. With the progress of research, it has become possible to extend the research to hierarchical structures other than spherical structures, such as porous microcubes. As a demonstration example of functional materials in solid-liquid-mixed systems, we have been expanding to supercapacitor materials, and in the future, we can expect widespread development not only in the energy and environment fields but also in the public health field.

Academic Significance and Societal Importance of the Research Achievements

本研究を通して確立した「自発的マイクロ球体化法」は、従来のスプレードライ法やエマルジョン法等の液相プロセスを全く必要とせず、無機系混合粉末を通常の大気炉加熱することのみで、均質な開気孔をもつハンドリングに優れた顆粒を得るものである。今後、エネルギー・環境分野はもちろんのこと、薬剤成分の徐放など公衆衛生分野等へも幅広い展開が期待できる。また、本研究で用いているMgO-Fe2O3-Nb2O5系マイクロ球体は、生体に有害な元素を含んでおらず、本研究の進捗によっては、将来的に骨補填剤などへの医療応用も可能になるのではないかと期待される。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • Research Products

    (35 results)

All 2020 2019 2018 2017 2016 Other

All Journal Article (10 results) (of which Peer Reviewed: 10 results,  Open Access: 7 results) Presentation (23 results) (of which Int'l Joint Research: 19 results,  Invited: 6 results) Remarks (2 results)

  • [Journal Article] Synthesis and color development mechanism of Li<sub>2</sub>CoTi<sub>3</sub>O<sub>8</sub> cyan pigments: effect of synthetic temperature2020

    • Author(s)
      KIMURA Saho、KANEKO Yuki、MARUMOTO Kazuhiro、SUZUKI Yoshikazu
    • Journal Title

      Journal of the Ceramic Society of Japan

      Volume: 128 Issue: 5 Pages: 260-266

    • DOI

      10.2109/jcersj2.20037

    • NAID

      130007839521

    • ISSN
      1348-6535, 1882-0743
    • Year and Date
      2020-05-01
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hydrothermal synthesis and electrochemical capacitor application of urchin-like NiCo<sub>2</sub>O<sub>4</sub> particles: effect of urea concentrations2019

    • Author(s)
      FUKUI Kazuki、NAKAMURA Yuya、ABE Hiroya、SUZUKI Yoshikazu
    • Journal Title

      Journal of the Ceramic Society of Japan

      Volume: 127 Issue: 11 Pages: 843-848

    • DOI

      10.2109/jcersj2.19069

    • NAID

      130007740866

    • ISSN
      1348-6535, 1882-0743
    • Year and Date
      2019-11-01
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reactive synthesis of porous MgAl<sub>2</sub>O<sub>4</sub> membranes on a macroporous Al<sub>2</sub>O<sub>3</sub>-based ceramic tube toward cross-flow ultrafiltration2019

    • Author(s)
      Y. Kamato, Y. Suzuki
    • Journal Title

      Journal of the Ceramic Society of Japan

      Volume: 127 Issue: 4 Pages: 267-271

    • DOI

      10.2109/jcersj2.18202

    • NAID

      130007622353

    • ISSN
      1348-6535, 1882-0743
    • Year and Date
      2019-04-01
    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Well-facetted spinel-type Co3O4 microcrystal assembly prepared by hydrothermal synthesis and post-thermal decomposition2019

    • Author(s)
      K. Fukui and Y. Suzuki
    • Journal Title

      Ceram. Int.

      Volume: 45 Issue: 7 Pages: 9288-9292

    • DOI

      10.1016/j.ceramint.2019.01.157

    • NAID

      120007127927

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Co-lean and Co-rich Li2CoTi3O8-based pigments: potential Co reduction and blue-green dichroism2019

    • Author(s)
      S. Kimura and Y. Suzuki
    • Journal Title

      Ceram. Int.

      Volume: in press Issue: 9 Pages: 12602-12607

    • DOI

      10.1016/j.ceramint.2019.03.036

    • NAID

      120007127925

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Facile synthesis of >99% phase-pure brookite TiO2 by hydrothermal conversion from Mg2TiO42018

    • Author(s)
      M. Machida, M. Kobayashi, Y. Suzuki, H. Abe
    • Journal Title

      Ceram. Int.

      Volume: 44 Issue: 14 Pages: 17562-17565

    • DOI

      10.1016/j.ceramint.2018.06.170

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reactive sintering and particle morphology control of beta"-alumina based water-purification filters2018

    • Author(s)
      K. Fukui and Y. Suzuki
    • Journal Title

      J. Mater. Sci.

      Volume: 53 Issue: 2 Pages: 1005-1013

    • DOI

      10.1007/s10853-017-1599-z

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Homogeneously bulk porous calcium hexaaluminate (CaAl12O19): Reactive sintering and microstructure development2018

    • Author(s)
      K. Kawaguchi, Y. Suzuki, T. Goto, S. H. Cho, T. Sekino
    • Journal Title

      Ceram. Int.

      Volume: 44 Issue: 4 Pages: 4462-4466

    • DOI

      10.1016/j.ceramint.2017.11.138

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Spherical porous granules in MgO-Fe2O3-Nb2O5 system: In situ observation of formation behavior using high-temperature confocal laser-scanning microscopy2017

    • Author(s)
      Y. Suzuki, H. Abe, H. Yamamoto, K. Ito, H. Inoue, M. Nakamura
    • Journal Title

      J. Eur. Ceram. Soc.

      Volume: 37 Issue: 16 Pages: 5339-5345

    • DOI

      10.1016/j.jeurceramsoc.2017.05.056

    • NAID

      120007128785

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reactively sintered porous MgAl2O4 for water-purification filter with controlled particle morphology2017

    • Author(s)
      Y. Kamato and Y. Suzuki
    • Journal Title

      Ceram. Int.

      Volume: 43 Issue: 16 Pages: 14090-14095

    • DOI

      10.1016/j.ceramint.2017.07.145

    • NAID

      120007134724

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Reactive sintering and particle morphology control of double-oxide based water purification filters2019

    • Author(s)
      Yoshikazu Suzuki
    • Organizer
      The 2nd International Conference on Material Strength and Applied Mechanics (MSAM 2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Reactive synthesis, microstructure, and pore-size control of oxide-based spherical porous granules2019

    • Author(s)
      Yoshikazu Suzuki and Hiroya Abe
    • Organizer
      XVI ECerS Conference
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Preparation of Al2O3/3Y-ZrO2 porous composites and their application for a water purification filter2019

    • Author(s)
      Rei Hatori and Yoshikazu Suzuki
    • Organizer
      E-MRS 2019 Fall Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Synthesis of Li2CoTi3O8 nanoparticles via a citric acid method toward electrochemical capacitor applications2019

    • Author(s)
      Yuya Nakamura and Yoshikazu Suzuki
    • Organizer
      E-MRS 2019 Fall Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Uniformly Porous Ceramics with 3-D Network Structure (UPC-3D) Prepared by Pyrolytic Reactive Sintering2018

    • Author(s)
      Y. Suzuki
    • Organizer
      CIMTEC2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Reactive sintering and particle morphology control of ceramic water purification filters2018

    • Author(s)
      Y. Suzuki
    • Organizer
      CMCEE-12
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Reactive Sintering, Microstructure, and Liquid-Sustained-Release Function of Oxide-Based Spherical Porous Granules2018

    • Author(s)
      Y. Suzuki and H. Abe
    • Organizer
      AFMD2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 難合成酸化物の低環境負荷・低コスト合成への挑戦:拡散加速型反応焼結法および形態制御型溶液反応法2018

    • Author(s)
      鈴木義和
    • Organizer
      日本セラミックス協会 第31回秋季シンポジウム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] スピネル系多孔質薄膜の作製とナノフィルターへの応用2018

    • Author(s)
      鎌戸耀子、鈴木義和
    • Organizer
      日本セラミックス協会 第31回秋季シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] スーパーキャパシター応用に向けたNiCo2O4粉体粒子の作製と評価2018

    • Author(s)
      福井和輝、鈴木義和
    • Organizer
      日本セラミックス協会 第31回秋季シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] Preparation and characterization of NiCo2O4 particles for supercapacitor2018

    • Author(s)
      K. Fukui and Y. Suzuki
    • Organizer
      E-MRS 2018 Fall Meeting
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Preparation and mechanical properties of CaAl12O19/CaAl4O7 composites2018

    • Author(s)
      H. Yamashita and Y. Suzuki
    • Organizer
      E-MRS 2018 Fall Meeting
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Environmental friendly and low-cost syntheses of difficult-to-synthesize, multicomponent and metastable functional oxides2018

    • Author(s)
      Y. Suzuki
    • Organizer
      WAIM2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Preparation and characterization of NiMn2O4 particles toward supercapacitor application2018

    • Author(s)
      H. Ishitsuka and Y. Suzuki
    • Organizer
      MRS 2018 Fall Meeting
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Pseudobrookite-type self-organized spherical porous granules as potential energy storage2017

    • Author(s)
      Y. Suzuki and H. Abe
    • Organizer
      E-MRS2017 Spring Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] MgTi2O5 and related pseudobrookite-type ceramics2017

    • Author(s)
      Y. Suzuki
    • Organizer
      ECerS2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Preparation and water-filter application of porous spinel ceramics2017

    • Author(s)
      Y. Kamato and Y. Suzuki
    • Organizer
      ECerS2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Preparation of porous beta-alumina and application for water treatment filter2017

    • Author(s)
      K. Fukui and Y. Suzuki
    • Organizer
      ECerS2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Preparation and microstructure control of porous Calcium hexaluminate2017

    • Author(s)
      K. Kawaguchi, Y. Suzuki, T. Goto, S. H. Cho, T. Sekino
    • Organizer
      E-MRS2017 Fall Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of Li2CO3 addition on microstructure and thermal properties of porous MgTi2O5 ceramics2017

    • Author(s)
      Xinzhu Miao, Y. Suzuki
    • Organizer
      MRS2017 Fall Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Self-organized formation of spherical porous granules only by one-step heat-treatment2016

    • Author(s)
      Yoshikazu Suzuki, Hiroko Tokoro and Hiroya Abe
    • Organizer
      Shaping 6
    • Place of Presentation
      Ecole Nationale Superieure de Chimie de Montpellier, Montpellier, France
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 多孔質マイクロ球状粒子の自発的生成挙動の高温その場観察2016

    • Author(s)
      鈴木 義和, 阿部 浩也, 山本 啓, 伊藤 和博, 井上 裕滋, 中村 誠友己
    • Organizer
      日本セラミックス協会 第29回秋季シンポジウム
    • Place of Presentation
      広島大学(東広島キャンパス)(広島県東広島市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] Self-organized formation of spherical porous granules only by one-step heat-treatment2016

    • Author(s)
      Yoshikazu Suzuki, Hiroko Tokoro and Hiroya Abe
    • Organizer
      WAIM2016
    • Place of Presentation
      Liston Hotel Shanghai, Shanghai, China
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Remarks] 無機系エネルギー・環境材料研究室

    • URL

      http://www.ims.tsukuba.ac.jp/~suzuki_lab/index.html

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report 2017 Annual Research Report
  • [Remarks] 無機系エネルギー・環境材料 鈴木義和研究室

    • URL

      http://www.ims.tsukuba.ac.jp/~suzuki_lab/index.html

    • Related Report
      2016 Annual Research Report

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Published: 2016-04-21   Modified: 2021-02-19  

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