| Budget Amount *help |
¥24,180,000 (Direct Cost: ¥18,600,000、Indirect Cost: ¥5,580,000)
Fiscal Year 2018: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2017: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
Fiscal Year 2016: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
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| Outline of Final Research Achievements |
In this study, we developed new methods analyzing germline mutations comprehensively by using mutation accumulation mouse lines. These include uncovering several traits of germline mutations, the mutagenesis mechanism and physiological function of germline mutations. Based on this method, we could easily evaluate the trans-generational effects of radiation exposures into germ cells. This method will be applicable for the future study of germline mutations.
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