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Species diversity of the phlebotomine sand fly in East Asia

Research Project

Project/Area Number 16K07476
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biodiversity/Systematics
Research InstitutionThe University of Tokyo

Principal Investigator

Sanjoba Chizu  東京大学, 大学院農学生命科学研究科(農学部), 助教 (70549667)

Research Collaborator Chi-Wei-Tsai  国立台湾大学, 昆虫学研究科, 助教
Zhang Ling-Min  ジン南大学, 医学部・寄生虫学教室, 教授
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords双翅目昆虫 / サシチョウバエ / 日本 / S. squamirostris / Sergentomyia属 / 東京都 / 台湾 / 昆虫 / 多様性 / 形態学 / 分子遺伝学
Outline of Final Research Achievements

In Japan, the sand flies have not been investigated since 1958 in spite of their medical importance. Information on the current status of sand fly fauna and ecology in Japan is thus important. Sand flies have been considered to be rare in Japan, however, this research project reveal that the geographical distribution of the phlebotomine sand fly Sergentomyia squamirostris seems to be wide, and the species appears to be abundant in the Honshu, Shikoku, Kyushu, and Okinawa, not in Hokkaido area. Seasonal prevalence of S. squamirostris was surveyed in different climate area, S. squamirostris started to appear from June and disappear until October, and the numbers of sand flies become peak in August in each research area. According to the analysis of blood meal of female S. squamirostris, it is suggested that S. squamirostris tend to prefer the blood of reptiles. The distribution of S. squamirostris is confirmed in Japan and Jiangxi, China, but not in Mongolia and Taiwan.

Academic Significance and Societal Importance of the Research Achievements

サシチョウバエによる刺咬は発赤を伴い、痛みが強いとされ、しばしアレルギー反応を引き起こすのみならず、原虫によって引き起こされるリーシュマニア症という人獣共通感染症、サシチョウバエ熱と呼ばれるウイルスによる感染症、あるいはバルトネラ症(カリオン病)として知られる細菌による感染症等の媒介者でもある。地球規模での環境変動、外来動物の侵入、生物相の変化、これらの生態系の変化による感染症の侵入危機が叫ばれて久しい。本研究で得られた成果は、ひとたび国内に侵入すれば、日本の保健、医療に重大な脅威となることが明らかな節足動物媒介性感染症の防疫策を先見的に考える上で意義が大きい。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (22 results)

All 2019 2018 2017 2016

All Journal Article (12 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 9 results,  Open Access: 8 results,  Acknowledgement Compliant: 2 results) Presentation (9 results) (of which Int'l Joint Research: 3 results,  Invited: 3 results) Book (1 results)

  • [Journal Article] Oral activity of the antimalarial endoperoxide 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) against Leishmania donovani complex2019

    • Author(s)
      Kwofie Kofi Dadzie、Sato Kai、Sanjoba Chizu、Hino Akina、Shimogawara Rieko、Amoa-Bosompem Michael、Ayi Irene、Boakye Daniel A.、Anang Abraham K.、Chang Kyung-Soo、Ohashi Mitsuko、Kim Hye-Sook、Ohta Nobuo、Matsumoto Yoshitsugu、Iwanaga Shiroh
    • Journal Title

      PLOS Neglected Tropical Diseases

      Volume: 13 Issue: 3 Pages: 7235-7235

    • DOI

      10.1371/journal.pntd.0007235

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Clinical Characteristics and Haematological Parameters Associated With Visceral Leishmaniasis in Bangladeshi Individuals2018

    • Author(s)
      Sarkar SR, Ray NC, Khan ER, Haque N, Hossain MA, Paul SK, Noiri E, Matsumoto Y, Sanjoba C.
    • Journal Title

      Mymensingh Med J

      Volume: 27 Pages: 496-503

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] MRP14 is dispensable for LPS-induced shock in BALB/c mice.2018

    • Author(s)
      Mizobuchi H, Fujii W, Ishizuka K, Wang Y, Watanabe S, Sanjoba C, Matsumoto Y, Goto Y.
    • Journal Title

      Immunol Lett

      Volume: 194 Pages: 13-20

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cutaneous leishmaniasis caused by Leishmania tropica in Israel.2018

    • Author(s)
      Uchida S, Oiso N, Sanjoba C, Matsumoto Y, Yanagihara S, Annoura T, Kato Y, Shirano M, Goto Y, Kawada A.
    • Journal Title

      J Dermatol

      Volume: 印刷中 Issue: 9

    • DOI

      10.1111/1346-8138.14300

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Additional distribution record of Sergentomyia (Neophlebotomus) squamirostris (Newstead) (Diptera:Psychodidae)2017

    • Author(s)
      Sanjoba C, Omachi S, Sato K, Matsumoto Y.
    • Journal Title

      Med Entomol Zool

      Volume: 68 Pages: 45-48

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] B-cell activating factor deficiency suppresses splenomegaly during Leishmania donovani infection.2017

    • Author(s)
      Omachi S, Fujii W, Azuma N, Morimoto A, Sanjoba C, Matsumoto Y, Goto Y
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 489 Pages: 528-533

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Additional distribution record of Sergentomyia (Neophlebotomus) squamirostris (Newstead) (Diptera: Psychodidae) from Tokyo, Japan2017

    • Author(s)
      Sanjoba C, Omachi S, Sato K, Matsumoto Y.
    • Journal Title

      Med Entomol Zool

      Volume: 2

    • NAID

      130006870768

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] IL-25, IL-33 and TSLP receptor are not critical for development of experimental murine malaria2016

    • Author(s)
      Akiko Shibuia, Ayako Takamori, Mohammed E.M. Tolbaa, Aya Nambu, Eri Shimura, Sachiko Yamaguchi, Chizu Sanjoba, Hajime Suto, Katsuko Sudo, Ko Okumura, Sumio Sugano, Hideaki Morita, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 5 Pages: 191-195

    • DOI

      10.1016/j.bbrep.2015.12.007

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Hemophagocytosis in experimental visceral leishmaniasis by Leishmania donovani.2016

    • Author(s)
      Morimoto A, Omachi S, Osada Y, Chambers JK, Uchida K, Sanjoba C, Matsumoto Y, Goto Y.
    • Journal Title

      PLoS Negl Trop Dis

      Volume: 10 Issue: 3 Pages: 1-16

    • DOI

      10.1371/journal.pntd.0004505

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Medical Entomology in Meiji period2016

    • Author(s)
      Sanjoba C, Kurihara T.
    • Journal Title

      Proc Res Grp Pestology

      Volume: 13 Pages: 33-38

    • NAID

      40021044713

    • Related Report
      2016 Research-status Report
  • [Journal Article] A list of literatures on mosquito studies in Japan during the Meiji period (1868-1911)2016

    • Author(s)
      Kurihara T, Sanjoba C.
    • Journal Title

      Proc Res Grp Pestology

      Volume: 13 Pages: 7-31

    • NAID

      40021044702

    • Related Report
      2016 Research-status Report
  • [Journal Article] The leterature on mosquito studies in Japan during the Meiji period, especially from 1902 to 1911 (addendum No. 2)2016

    • Author(s)
      Kurihara T, Sanjoba C.
    • Journal Title

      Proc Res Grp Pestology

      Volume: 13 Pages: 1-5

    • Related Report
      2016 Research-status Report
  • [Presentation] バングラデシュにおけるリーシュマニア症媒介昆虫サシチョウバエの年間発生消長2019

    • Author(s)
      三條場千寿
    • Organizer
      第71回日本衛生動物学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] バングラデシュにおけるサシチョウバエの殺虫剤抵抗性遺伝子変異の探索2019

    • Author(s)
      黒木章弘
    • Organizer
      第71回日本衛生動物学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 外来種による新たな人獣共通感染症伝播サイクル2019

    • Author(s)
      三條場千寿
    • Organizer
      第66回日本生態学会大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Molecular mechanism and biological function of hemophagocytosis during Leishmania donovani infection2019

    • Author(s)
      森本 彩子
    • Organizer
      第88回日本寄生虫学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Community knowledge and preventive practices regarding kala-azar in an endemic area in Bangladesh.2017

    • Author(s)
      Chizu Sanjoba
    • Organizer
      6th World Congress on Leishmaniasis
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] サシチョウバエの生態2017

    • Author(s)
      三條場千寿
    • Organizer
      第13回 双翅目談話
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] One Health approach to the control of neglected tropical diseases with special attention on Leishmaniasis in Asia2017

    • Author(s)
      chizu Sanjoba
    • Organizer
      ZEF-IPADS 共同シンポジウム「アフリカ・アジアにおけるワンヘルスの展開」
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] An Entomological Survey for Sand flies in Two Counties of Taiwan2016

    • Author(s)
      Yusuf Ozbel
    • Organizer
      International Symposium On Phlebotomine Sandflies IX
    • Place of Presentation
      Reims, France
    • Year and Date
      2016-06-28
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Vector control using long-lasting insecticidal nets against Kala-azar in Bangladesh2016

    • Author(s)
      Chizu Sanjoba
    • Organizer
      International Symposium On Phlebotomine Sandflies IX
    • Place of Presentation
      Reims, France
    • Year and Date
      2016-06-28
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Book] 招かれない虫たちの話、 第10章「サシチョウバエの分類・同定とその対策」2017

    • Author(s)
      三條場千寿
    • Total Pages
      222
    • Publisher
      東海大学出版
    • ISBN
      9784486021254
    • Related Report
      2017 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

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