Development of the Pathophysiological Model and NeuroRehabilitation of DCD
| Project/Area Number |
16K09981
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Mukogawa Women's University (2018-2019)
社会福祉法人兵庫県社会福祉事業団兵庫県立リハビリテーション中央病院(子どもの睡眠と発達医療センター) (2016-2017) |
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Principal Investigator |
NAKAI AKIO 武庫川女子大学, 教育研究所, 教授 (50240784)
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| Project Period (FY) |
2016-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 発達性協調運動障害（DCD) / 神経発達障害 / ニューロリハビリテーション / ニューロモデュレーター / 薬物療法 / DCDQ日本語版 / M-ABC2日本語版 / 身体性（Embodiment） / 発達性協調運動障害 / 発達性協調運動障害（DCD） / 自閉症スペクトラム障害 / 注意欠如・多動性障害 / 運動の内部モデル / 発達小児科学 / 神経科学 |
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| Outline of Final Research Achievements |
In Developmental Coordination Disorder (DCD), we investigated the effects of DCD trait on child development,and the relationship between other neurodevelopmental disorders, such as autism spectrum disorder. And we evaluated the neural basis of DCD, such as internal model, visuo-motor temporal integration, embodiment (sense of self ownership, sense of self agency), and imitation, to develop the pathophysiological model of DCD. Based on this model, we developed the methods of intervention to child DCD, such as neurorehabilitation and drug therapy as a neuromodulator.
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| Academic Significance and Societal Importance of the Research Achievements |
従来、身体の問題、神経発達障害の単なる併存障害として扱われがちであった発達性協調運動障害（DCD）だが、神経発達障害は「協調」という「身体性 Embodiment」を基盤とした認知発達の偏り・アンバランスという新しいアプローチから、DCDの神経基盤の解明と病態モデルの構築、協調の問題の多動や向社会性、情緒など発達への影響、他の神経発達障害との関係を明らかにし、さらに、ニューロリハビリテーション法を含めた介入方法やニューロモデュレーターとしての薬物療法の開発を行った本研究の成果は、学術的価値が高いだけでなく、神経発達障害の医療・療育の現場での応用につながり、その意義は極めて大きいと考えられる。
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Report
(5 results)
Research Products
(117 results)
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[Journal Article] Manual Dexterity Is a Strong P redictor of Visuo-Motor Tempor al Integration in Children.2018
Author(s)
Nobusako S, Sakai A, Tsujimoto T, Shuto T, Nish i Y, Asano D, Furukawa E, Zama T, Osumi M, Shim ada S, Morioka S, Nakai A.
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Journal Title
Frontiers in Psychology
Volume: 9
Pages: 948-948
Related Report
Peer Reviewed / Open Access
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[Journal Article] Deficits in visuo-motor temporal integration impacts manual dexterity in probable developmental coordination disorder.2018
Author(s)
Nobusako S, Sakai A, Tsujimoto T, Shuto T, Nishi Y,Asano D, Furukawa E, Osumi M, Shimada S, Morioka S, Nakai A.
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Journal Title
Frontiers in Neurology
Volume: 9
Pages: 114-114
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Coordination difficulties in preschool-aged children are associated with maternal parenting stress: A community-based cross-sectional study.2017
Author(s)
Takahashi M, Adachi M, Takayanagi N, Yasuda S, Tanaka M, Osato-Kaneda A, Masuda T, Nakai A, Saito M, Kuribayashi M, Nakamura K
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Journal Title
Research inDevelopmental Disabilities.
Volume: 70
Pages: 11-23
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Impacts of Perinatal Dioxin Exposure on Motor Coordination and Higher Cognitive Development in Vietnamese Preschool Children: A Five-Year Follow-Up2015
Author(s)
Tran NN, Pham TT, Ozawa K, Nishijo M, Nguyen AT, Tran TQ, Hoang LV, Tran AH, Phan VH, Nakai A, Nishino Y, Nishijo H.
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Journal Title
PLoS ONE
Volume: 11
Issue: 1
Pages: e0147655-e0147655
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Presentation] The Changes of Visual Perception in ADHD by Atomoxetine Therapy,2017
Author(s)
Kashiwagi M, Tanabe T, Ogino M, Ooba C, Nomura S, Okumura T, Nakai A, Wakamiya E, Tamai H.
Organizer
The 12th International Conference on Developmental Coordination Disorder (DCD-12),
Related Report
Int'l Joint Research
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[Presentation] he Little Developmental Coordination Disorder Questionnaire (LDCDQ) Cross-cultural Collaboration for identifying Motor Delay in Young Pre-schoolers.2017
Author(s)
Rihtman T, Wilson B, Cermak S, Rodger S, Kennedy-Behr A, Snowdon L, Schoemaker M, Cantell M, Houwen S, Jover M, Albaret J, Ray-KaesernS, Magalhaes L, Cardoso A, Van Waelvelde H, Vincon S, Tseng M, Pienaar A, Coetzee D, Nakai A, Martini R, Tercon J, Green D, Impertore E, Diaz J, Parursh S.
Organizer
The 12th International Conference on Developmental Coordination Disorder (DCD-12),
Related Report
Int'l Joint Research
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[Presentation] Prevalence and Comorbidities of DCD using DSM-5, comparison of Motor and Cognitive Functions at Preschool age in a Japanese Community.2017
Author(s)
Saito M, Osato-Kaneda A, Tanaka M, Matsuda T, Yoshida S, Sakamoto Y, Matsubara Y, Takayanagi N, Adachi M, Takahashi M, Yasuda S, Kuribayashi M, Nakai A, Miyahara M, Nakamura K.
Organizer
The 12th International Conference on Developmental Coordination Disorder (DCD-12),
Related Report
Int'l Joint Research
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[Presentation] Evaluation of Factor Structure equivalence of the Developmental Coordination Disorder Questionnaire across genders in Japanese Preschool Children: HFC study2017
Author(s)
Tanaka M, Saito M, Osato-Kaneda A, Matsuda T, Takayanagi N, Takahashi M, Adachi M, Yasuda S, Yoshida S, Kuribayashi M, Nakai A, Miyahara M, Nakamura K, Sakamoto Y.
Organizer
The 12th International Conference on Developmental Coordination Disorder (DCD-12),
Related Report
Int'l Joint Research
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[Presentation] Developmental Coordination Trait in Japanese Pre-schoolers Impact on Parenting Stress.2017
Author(s)
Takahashi M, Adachi M, Takayanagi N, Yasuda S, Osato-Kaneda A, Mikami M, Nakai A, Saito M, Kuribayashi M, Nakamura K.
Organizer
The 12th International Conference on Developmental Coordination Disorder (DCD-12),
Related Report
Int'l Joint Research
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