| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
This study clarified the subjects below to evaluate the effective treatment for coronary artery disease based on coronary flow reserve (CFR). 1. Development of noninvasive CFR measurement: we developed the scan protocol and data analysis to estimate CFR by using O15-water PET /CT. 2. Effects of optical medical therapy on CFR: Because the rate of achievement of optical medical therapy was high as 71% at baseline, the CFR did not change at 6 months. 3. Effects of coronary revascularization: Among 72 patients with coronary artery disease, 28 and 20 patients underwent percutaneous coronary intervention and coronary artery bypass grafting, respectively. The CFR less than 2.0 or the SYNTAX score more than and equal to 23 are associated with increase in CFR by coronary revascularization.
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