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Embodiment of neuronal dissociate culture by reservoir computing

Research Project

Project/Area Number 16K14191
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionThe University of Tokyo

Principal Investigator

Takahashi Hirokazu  東京大学, 先端科学技術研究センター, 講師 (90361518)

Project Period (FY) 2016-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords分散培養 / 脳 / 神経細胞 / 培養 / 電気計測 / リザバー / 神経回路 / CMOS / リザバー計算
Outline of Final Research Achievements

This work investigated in primary dissociated cultures how neural circuits produce diversity of activity repertoire and how the static neural circuits produce stable, dynamic spatiotemporal patterns. In particular, considering a framework of reservoir computation, we characterized the neuronal circuits as a reservoir. We demonstrated that sequential propagation of neuronal sub-populations during synchronized activity underlies stability of neural representation. We also found a spontaneous, state-dependent property of neuronal activities, which is likely to play an important role to produce diversity of activity repertoire.

Report

(2 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (10 results)

All 2017 2016 Other

All Int'l Joint Research (1 results) Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (7 results) (of which Int'l Joint Research: 3 results,  Invited: 4 results) Remarks (1 results)

  • [Int'l Joint Research] ETH Zurich(スイス)

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Development of neural population activity toward self-organized criticality2017

    • Author(s)
      Yuichiro Yada, Takeshi Mita, Akihiro Sanada, Ryuichi Yano, Ryohei Kanzaki, Douglas J. Bakkum, Andreas Hierlemann and Hirokazu Takahashi
    • Journal Title

      Neuroscience

      Volume: 343 Pages: 55-65

    • DOI

      10.1016/j.neuroscience.2016.11.031

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] 繰り返し同期誘発刺激による培養神経回路の記憶の操作2017

    • Author(s)
      角田颯飛,矢田祐一郎,神崎亮平,高橋宏知
    • Organizer
      電気学会研究会 医用・生体工学研究会
    • Place of Presentation
      東京
    • Year and Date
      2017-03-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] 知能を生み出す脳のメカニズム2017

    • Author(s)
      高橋宏知
    • Organizer
      応用物理学会有機分子・バイオエレクトロニクス分科会
    • Place of Presentation
      東京
    • Year and Date
      2017-02-21
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Intelligence emerging from neural system2017

    • Author(s)
      Hirokazu Takahashi
    • Organizer
      NICT-NSF Collaborative Workshop on Computation Neuroscience
    • Place of Presentation
      大阪
    • Year and Date
      2017-01-17
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] メカ屋のための脳科学入門2016

    • Author(s)
      高橋宏知
    • Organizer
      SEMICON JAPAN 2016
    • Place of Presentation
      東京
    • Year and Date
      2016-12-14
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 神経細胞の分散培養からの知能の創発2016

    • Author(s)
      高橋宏知
    • Organizer
      第219回 有機エレクトロニクス材料 (JOEM) 研究会
    • Place of Presentation
      東京
    • Year and Date
      2016-10-12
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Dimensionality reduction of massively recorded activity reveals sequential structure and state-dependency in dissociated neurons2016

    • Author(s)
      Y. Yada, R. Kanzaki and H. Takahashi
    • Organizer
      10th International Meeting on Substrate-Integrated Electrode Arrays
    • Place of Presentation
      Reutlingen, Germany
    • Year and Date
      2016-06-28
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Reservoir computing with dissociated neuronal culture2016

    • Author(s)
      H. Takahashi, S. Yasuda, Y. Yada and R. Kanzaki
    • Organizer
      10th International Meeting on Substrate-Integrated Electrode Arrays
    • Place of Presentation
      Reutlingen, Germany
    • Year and Date
      2016-06-28
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Remarks] 研究代表者のホームページ

    • URL

      http://www.brain.imi.i.u-tokyo.ac.jp/~takahashi/index.html

    • Related Report
      2016 Annual Research Report

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Published: 2016-04-21   Modified: 2018-03-22  

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