| Project/Area Number |
16K14895
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied microbiology
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
Kato Souichiro 国立研究開発法人産業技術総合研究所, 生物プロセス研究部門, 主任研究員 (30597787)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 微生物 / 鉄腐食 / 酢酸生成菌 / ゲノム解析 / シトクロム / 細胞外電子伝達 / 比較ゲノム解析 / 酢酸生成 / 比較ゲノム / 遺伝子発現解析 |
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| Outline of Final Research Achievements |
In this study, we aimed to elucidate the molecular mechanism of energy metabolism of iron corroding acetogens that produces acetate from carbon dioxide using metallic iron as the sole energy source. We investigated iron corrosion activities of an iron corroding acetogen (Sporomusa sp. GT1) and related acetogens, and found that only some Sporomusa strains had iron corroding activities and the other acetogens not. Then we conducted comparative genomic analysis on the acetogenic strains. The Sporomusa strains that showed iron corroding activities did not encode the genes for multiheme c-type cytochromes, indicating that they have a different extracellular electron transfer mechanism than known Gram-negative bacteria.
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