| Project/Area Number |
16K15367
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Hygiene and public health
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| Research Institution | Hokkaido University |
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Principal Investigator |
Hanley Sharon 北海道大学, 医学研究院, 特任講師 (80529412)
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| Research Collaborator |
Simms Kate
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | HPV vaccine / vaccine hesitancy / cervical cancer / Policy1-Cervix model / impact analysis / HPVワクチン / 接種率向上 / 海外調査 / 英国 / オーストラリア / HPV Vaccine / public health / coverage / education / international comparison / vaccine confidence / vaccine hestitancy |
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| Outline of Final Research Achievements |
HPV vaccine confidence decreased in Japan after unfounded reports on vaccine safety appeared in the media. This study aimed to evaluate HPV vaccine acceptance in Japanese parents of adolescent girls living in the UK and Australia. A secondary aim was to quantify the impact of suspension of proactive recommendations for the HPV vaccine in Japan to date.
The most important factor for deciding whether to vaccinate a daughter against HPV was the opinion of the mother, regardless of whether the father had a bio/medical background or not.
Regarding the impact of suspension of proactive recommendations for the HPV vaccine, we found around 55,800-63,700 preventable cases and 9,300-10,800 preventable deaths from cervical cancer will occur over the next 50 years compared to if uptake has remained high. However, swift recovery of uptake in 2020 resulting in 70% coverage for 12yr old girls and 50% uptake in catch-up cohorts aged 13-20yrs with HPV9 could prevent around 80% of these deaths.
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| Academic Significance and Societal Importance of the Research Achievements |
The results suggest interventions focusing on mothers are important to help increase HPV vaccine confidence and acceptability. The impact analysis shows that swift restoration of coverage, including catch-up vaccination, could mitigate most of the damage caused by suspension of recommendations.
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