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Beam-profile measurement method using radiation-induced coloration in irradiation field for boron neutron capture therapy

Research Project

Project/Area Number 16K15578
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionKyoto University

Principal Investigator

Sakurai Yoshinori  京都大学, 複合原子力科学研究所, 准教授 (20273534)

Co-Investigator(Kenkyū-buntansha) 高田 卓志  京都大学, 複合原子力科学研究所, 助教 (60444478)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords硼素中性子捕捉療法(BNCT) / ビームプロファイル / 放射線着色 / 粒子線治療 / 放射線計測 / 品質保証/品質管理(QA/QC) / 医学物理 / 放射線工学 / BNCT / QA/QC
Outline of Final Research Achievements

The effectiveness of the beam-profile measurement method using radiation-induced coloration in irradiation field for boron neutron capture therapy (BNCT) was confirmed. For “radiation-induced coloration panel”, the materials were selected based on the data from experiment and simulation. A prototype of “coloration-panel scanner” was prepared, which consisted of visible light source, photoreceptor device and image reconstruction device. The characteristics of the prepared coloration panel and coloration-panel scanner were evaluated using Heavy Water Neutron Irradiation Facility of Kyoto University Reactor (KUR) and Cobalt Gamma-ray Irradiation Facility. From the analytic results for the obtained data, the feasibility, validity, estimation-accuracy, etc. were confirmed for this method.

Academic Significance and Societal Importance of the Research Achievements

本研究の学術的特色は、放射線により着色される物質に着目し、それを利用してBNCT用照射場中の熱・熱外中性子、高速中性子、γ線を弁別し、ビームプロファイル測定を簡便・低労力・省時間で試みることにある。現在、国内外の数カ所で様々なタイプの中性子照射場においてBNCTが実施されつつある状況にあり、各照射場で共通したQA/QCの整備が急務となっている。共通化のためには、手法の簡便化・低労力化・省時間化が重要因子であり、本研究で検討している手法は、照射場のビームプロファイルのQA/QCにおいて有効なツールになると考えている。本研究の成果はBNCTの高度化・一般化のために意義のあるものと考えている。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (16 results)

All 2018 2017 2016

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (13 results) (of which Int'l Joint Research: 10 results,  Invited: 3 results)

  • [Journal Article] 国内のBNCT施設の現状2018

    • Author(s)
      櫻井良憲
    • Journal Title

      放射線化学会誌

      Volume: 105 Pages: 41-46

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] イメージングプレートを用いた中性子捕捉療法ビーム成分分布の品質保証2017

    • Author(s)
      田中憲一,櫻井良憲,梶本 剛,田中浩基,高田卓志,村田 勲,玉置真悟,遠藤 暁
    • Journal Title

      放射線

      Volume: 43(1) Pages: 3-7

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] ホウ素中性子捕捉療法におけるゲル線量計の利用2017

    • Author(s)
      櫻井良憲,内田良平
    • Journal Title

      放射線

      Volume: 37(3) Pages: 190-194

    • NAID

      130006337872

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] A study on improvement method of dose distribution using water bath in boron neutron capture therapy for foot tumors2018

    • Author(s)
      Y. Sakurai, T. Takata, H. Tanaka, T. Fujimoto, Y. Tamari, N. Kondo, Y. Kinashi, S. Masunaga and M. Suzuki
    • Organizer
      World Congress on Medical Physics and Biomedical Engineering (WC2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Radiation quality dependence of polymer gel dosimeters in therapeutic neutron irradiation field2018

    • Author(s)
      R. Uchida, S. Hayashi, T. Takata and Y. Sakurai
    • Organizer
      18th International Congress on Neutron Capture Therapy
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Investigation of beam component monitor for BNCT using gel detector2018

    • Author(s)
      K. Tanaka, Y. Murakami, R. Maruta, T. Kajimoto, Y. Sakurai, S. Hayashi, H. Tanaka, T. Takata and S. Endo
    • Organizer
      18th International Congress on Neutron Capture Therapy
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Fundamental knowledge for microdosimetry in boron neutron capture therapy2018

    • Author(s)
      Y. Sakurai
    • Organizer
      Micro-Mini & Nano Dosimetry Workshop and Innovative Technologies in Radiation Oncology ((MMND-ITRO 2018)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Current Status of BNCT based on Research Reactor R&D in Japan2017

    • Author(s)
      Y. Sakurai, H. Tanaka, T. Takata, T. Watanabe, N. Kondo, Y. Kinashi, S. Masunaga, M. Suzuki, K. Ono and A. Maruhashi
    • Organizer
      The 3rd International Symposium on the Application of Nuclear Technology as a Key Element to Promote Competitive National Industrial Products: Energy, Health, Agriculture, Industry and Environment
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Investigation of 6Li compound suitable for beam component measurement using polymer gel detector for BNCT2017

    • Author(s)
      K. Tanaka, Y. Murakami, S. Hayashi, T. Kajimoto, Y. Shigetake, Y. Sakurai, H. Tanaka and S. Endo
    • Organizer
      The 8th Japan-Korean Joint Meeting on Medical Physics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Present status and future plan for physical engineering and medical physics for BNCT in KURRI2017

    • Author(s)
      Y. Sakurai, H. Tanaka, T. Takata, M. Suzuki, S. Masunaga, Y. Kinashi, N. Kondo, T. Watanabe, Y. Tamari, Y. Sanada, K. Ono and A. Maruhashi
    • Organizer
      9th Young Researchers’ Boron Neutron Capture Therapy Meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] nvestigation of applicability of polymer gel dosimeters with Li compounds to dosimetry in boron neutron capture therapy2017

    • Author(s)
      R. Uchida, S. Hayashi, A. Sakon, G. Wakabayashi, K. Tanaka and Y. Sakurai
    • Organizer
      9th Young Researchers’ Boron Neutron Capture Therapy Meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 中性子に対するMAGATポリマーゲル線量計の線質依存性評価2016

    • Author(s)
      内田良平,櫻井良憲,林 慎一郎,田中憲一,髙田卓志,楢林正流,鈴木 実
    • Organizer
      第5回3Dゲル線量計研究会
    • Place of Presentation
      京都大学宇治おうばくプラザ(京都府宇治市)
    • Year and Date
      2016-12-03
    • Related Report
      2016 Research-status Report
  • [Presentation] Study of polymer gel dosimeter response in neutron irradiation fields2016

    • Author(s)
      R.Uchida, Y.Sakurai, S.Hayashi, K.Tanaka, T.Takata, M.Narabayashi and M.Suzuki
    • Organizer
      17th International Congress on Neutron Capture Therapy
    • Place of Presentation
      University of Missouri, Columbia, USA
    • Year and Date
      2016-10-02
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Progress in Reactor and Accelerator Based BNCT at Kyoto University Research Reactor Institute2016

    • Author(s)
      Y.Sakurai, H.Tanaka, T.Takata, N.Kondo, Y.Kinashi, S.Masunaga, M.Suzuki, K.Ono and A.Maruhashi
    • Organizer
      The 26th International Nuclear Physics Conference (INPC2016)
    • Place of Presentation
      Adelaide Convention Centre, Adelaide, Australia
    • Year and Date
      2016-09-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 放射線による着色を利用した硼素中性子捕捉療法用照射場のビームプロファイル測定手法に関する検討2016

    • Author(s)
      櫻井良憲,内田良平,高田卓志,田中浩基
    • Organizer
      日本医学物理学会第112回学術大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2016-09-08
    • Related Report
      2016 Research-status Report
  • [Presentation] 中性子照射場におけるポリマーゲル線量計の応答特性(2)2016

    • Author(s)
      内田良平,櫻井良憲,林 慎一郎,田中憲一,髙田卓志,楢林正流,鈴木 実
    • Organizer
      日本中性子捕捉療法学会第13回学術大会
    • Place of Presentation
      東京大学伊藤謝恩ホール(東京都文京区)
    • Year and Date
      2016-08-06
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2020-03-30  

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