| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
As an approach to "personalized medicine" for delivering better treatments to each patient, this research project focused on "dynamic treatment regimes," which use biomarker information varying with treatment sequence and/or response to previous treatment to adaptively select subsequent treatment strategy. Among the candidate dynamic regimes, we should select the "optimal treatment regime" that maximizes the efficacy on targeted long-term clinical outcomes through validated statistical methods applied to adequately designed clinical studies including multistage-randomized clinical trials. I have made some methodological contribution for tackling challenges in estimating optimal treatment regimes from a statistical causal inference perspective.
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