| Project/Area Number |
16K19385
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Cardiovascular medicine
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| Research Institution | Tohoku University |
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Principal Investigator |
Hao Kiyotaka 東北大学, 大学病院, 助教 (30647954)
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 急性心筋梗塞 / 急性期医療 / 12誘導心電図伝送 / 救急隊 / Door to balloon time / 救急医療 / 循環器 / 12誘導心電図 |
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| Outline of Final Research Achievements |
To examine the clinical impact of prehospital 12-lead electrocardigram (ECG) transmission system for the management of patients with acute myocardial infarction (AMI), we enrolled the 305 AMI patients in the Osaki and Sennan areas, Miyagi prefecture between 2015 and 2017. Of those, prehospital ECG transmissions were performed in 130 patients (43.3%). In patients with prehospital ECG transmission, as compared with those without it, the prevalence of ST-segment elavation myocardial infarction (STEMI) tended to be higher (80.6% vs. 71.4%, P=0.07). When the patients were divided into STEMI and non-STEMI (NSTEMI) groups, in the STEMI group, door to balloon time (D2BT) was significantly shorter in patients with prehospital ECG compared with those without it [median; 59(47-80) min vs. 73(57-99) min, P<0.01]. In contrast, in the NSTEMI group, there was no significant difference in D2BT between patients with and without prehospital ECG transmission [100(88-180) min vs. 110(75-492) min, P=0.71].
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| Academic Significance and Societal Importance of the Research Achievements |
急性心筋梗塞(AMI)患者に対する「プレホスピタル12誘導心電図」の施行によって、来院から再灌流までの時間が短縮することが報告されているが、本邦の特に郡部においてはその効果を詳細に検討した研究はこれまでに認めなかった。しかし、本研究の結果から宮城県郡部において、AMI患者に対するプレホスピタル12誘導心電図の導入によって救急隊現着から病院搬送までの時間は延長させずに来院から再灌流までの時間を短縮できることが示され、特にST上昇型心筋梗塞患者においてより有効であった。本研究の結果から、本邦におけるAMIの急性期医療体制に改善の余地があることが示され、この点から社会的意義があると考えられた。
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