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Development of tools for analysis of comprehensive signals of subcellular biomolecules

Research Project

Project/Area Number 17066004
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionKyoto University

Principal Investigator

UEDA Mitsuyoshi  Kyoto University, 大学院・農学研究科, 教授 (90183201)

Co-Investigator(Kenkyū-buntansha) TAKAGI Masahiro  北陸先端科学技術大学院大学, マテリアルサイエンス研究科, 教授 (00183434)
KONDO Akihiko  神戸大学, 大学院・工学研究科, 教授 (40205547)
YOSHIDA Kazuya  奈良先端科学技術大学院大学, バイオサイエンス研究科, 准教授 (50252622)
NAKAYAMA Hideki  奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 (30324982)
FUKUSAKI Eiiciro  大阪大学, 大学院・工学研究科, 教授 (40273594)
ITO Yoshihiro  独立行政法人理化学研究所, 伊藤ナノ医工学研究室, 主任研究員 (40192497)
Project Period (FY) 2005 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥262,900,000 (Direct Cost: ¥262,900,000)
Fiscal Year 2008: ¥59,200,000 (Direct Cost: ¥59,200,000)
Fiscal Year 2007: ¥57,600,000 (Direct Cost: ¥57,600,000)
Fiscal Year 2006: ¥71,100,000 (Direct Cost: ¥71,100,000)
Fiscal Year 2005: ¥75,000,000 (Direct Cost: ¥75,000,000)
Keywords細胞内情報伝達動態 / ワンセルプロテオーム / 脂質ラフト / 環境ストレス応答 / 代謝プロファイリング / シグナル伝達 / 蛍光プローブ / 侵襲的デジタル定量解析 / 侵襲的デジタル定解析 / モノリスチップ / 光固定化 / メタボロミクス / タンパク質のリン酸化 / ストレス / ゼブラフィッシュ / 代謝変動 / マイクロアレイ / プロテオミクス / リン酸化タンパク質 / ホスホプロテオミクス / 情報伝達 / レセプタータンパク質 / フォールディング / 化学増幅法
Research Abstract

植田は、細胞内情報伝達動態の侵襲的デジタル定量用ワンセルプロテオームチップを開発した。高木は、生細胞膜に近い構造のラフト含有非対称リポソームの作製方法を開発した。近藤は、酵母を用いたシグナル伝達システムを開発した。仲山は、好塩性細胞の金属ストレス応答遺伝子を同定した。福崎は、GC/MSおよびCE/MSを用いた基幹一次代謝系の網羅的解析システムを開発した。伊藤は、臨床応用酵素の新規蛍光プローブを開発した。

Report

(5 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (122 results)

All 2009 2008 2007 2006 2005 Other

All Journal Article (47 results) (of which Peer Reviewed: 28 results) Presentation (64 results) Book (8 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Construction of a novel detection system for protein.protein interactions using yeast G-protein signaling.2009

    • Author(s)
      Fukuda N, Ishii J, Tanaka T, Fukuda H and Kondo A.
    • Journal Title

      FEBS J. (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Performance of wide-pore monolithic silica column in protein separation2009

    • Author(s)
      H. Morisaka, et.al.
    • Journal Title

      J. Separation Science (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of Alzheimer's amyloid beta aggregation by capturing molecular trails of individual assemblies.2008

    • Author(s)
      Vestergaard, M., Hamada, T., Saito, M., Yajima, Y., Kudou, M., Tamiya, E., Takagi, M.
    • Journal Title

      Biochem. Biophys. Res. Comm. 377

      Pages: 725-728

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functions of HKT transporters in sodium transport in roots and in protecting leaves from salinity stress.2008

    • Author(s)
      Horie T, Sugawara M, Okunou K, Nakayama H, Schroeder JI, Shinmyo A, Yoshida K.
    • Journal Title

      Plant Biotech 25

      Pages: 233-239

    • NAID

      10021913328

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Construction of asymmetric cell-sized lipid vesicles from lipid-coated water-in-oil micro-droplets2008

    • Author(s)
      T. Hamada, et.al.
    • Journal Title

      J. Phys. Chem 112

      Pages: 14678-14681

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Profiling of primary metabolite by means of capillary electrophoresis-mass spectrometry and its application2008

    • Author(s)
      K. Harada, et.al.
    • Journal Title

      Plant Biotechnol 26

      Pages: 47-52

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Integrated metabolite and gene expression profiling revealing phytochrome Aregulation of polyamine biosynthesis of Arabidopsis thaliana2008

    • Author(s)
      K. Jumtee, et. al.
    • Journal Title

      J. Exp. Bot. (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative Analysis of Anionic Metabolites for Catharanthus roseus by Capillary Electrophoresis Using Sulfonated Capillary Coupled with Electrospray Ionization-Tandem Mass Spectrometry2008

    • Author(s)
      K. Harada, et. al.
    • Journal Title

      J. Biosci. Bioeng. 105

      Pages: 249-260

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A. Yeast-based fluorescence reporter assay of G protein-coupled receptor signaling for flow cytometric screening: FAR1-disruption recovers loss of episomal plasmid caused by signaling in yeast2008

    • Author(s)
      J. Ishii, et. al.
    • Journal Title

      Biochem. (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A. Rapid and efficient selection of yeast displaying a cell-surface protein using magnetic nanoparticles2008

    • Author(s)
      N. Fukuda, et. al.
    • Journal Title

      Biotechnol. Prog. (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functions of HKT transporters in sodium transport in roots and in protecting leaves from salinity stress2008

    • Author(s)
      T. Horie, et. al.
    • Journal Title

      Plant Biotechnol. (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of OsHAK genes encoding potassium iontransporters in rice2008

    • Author(s)
      T. Okada, et. al.
    • Journal Title

      Plant Biotechnol. (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 環境ストレス耐性向上の分子育種による植物バイオマス増産2008

    • Author(s)
      吉田和哉, ら
    • Journal Title

      バイオインダストリー 25

      Pages: 25-31

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Using model membranes for the study of amyloid beta: lipid interactions and neurotoxicity.2008

    • Author(s)
      M. Vestergaard, T. Hamada, M. Takagi
    • Journal Title

      Biotechnology and Bioengineering 99

      Pages: 753-763

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chelation of cadmium ions by phytochelatin synthase: role of the cysteine-rich C-terminal.2008

    • Author(s)
      M. Vestergaard, S. Matsumoto, S. Nishikori, K. Shiraki, K. Hirata, M. Takagi
    • Journal Title

      Analytical Science 24

      Pages: 277-281

    • NAID

      10021098648

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time course metabolic profiling in Arabidopsis thaliana cell cultures after salt stress treatment.2007

    • Author(s)
      Kim, J. K., E. Fukusaki et al
    • Journal Title

      J Exp Bot 58(3)

      Pages: 415-424

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Construction of a novel synergistic system for production and recovery of secreted recombinant proteins by the cell surface engineering2007

    • Author(s)
      S. Shibasaki, et. al.
    • Journal Title

      Appl. Microbiol. Biotechnol. 75

      Pages: 821-828

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-efficiency recovery of target cells using improved yeast display system for detection of protein-protein interactions2007

    • Author(s)
      N. Fukuda, et. al.
    • Journal Title

      Appl. Microbiol. Biotechnol. 76

      Pages: 151-158

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Femtosecond pulsed laser as a micro-scalpel for microdissection and isolation of specific sections from biological samples2007

    • Author(s)
      N. Sakakura, et. al.
    • Journal Title

      J. J. Appl. Physics 46

      Pages: 5859-5864

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of high-throughput screening system by single cell reaction using microchamber array chip2007

    • Author(s)
      T. Fukuda, et. al.
    • Journal Title

      J. Biosci. Bioeng. 104

      Pages: 241-243

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design of a serine protease-like catalytic triad on an antibody light chain displayed on the yeast cell surface2007

    • Author(s)
      N. Okochi, et. al.
    • Journal Title

      Appl. Microbiol. Biotechriol. 77

      Pages: 597-603

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 分子ディスプレイを用いた網羅的タンパク質解析2007

    • Author(s)
      植田充美
    • Journal Title

      バイオニクス 27

      Pages: 31-35

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of Metabolite Profile Data Using Batch-Learning Self-Organizing Maps2007

    • Author(s)
      J.Kim, et. al.
    • Journal Title

      J. Plant Biol. 50

      Pages: 517-521

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] メタボロミクス(代謝物総体解析)の食品工学への応用2007

    • Author(s)
      福崎英一郎
    • Journal Title

      生物工学 85

      Pages: 488-491

    • NAID

      110006479635

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 植物メタボロミクス技術の新展開2007

    • Author(s)
      福崎英一郎, 原田和生
    • Journal Title

      バイオサイエンスとインダストリー 65

      Pages: 498-504

    • NAID

      10019833619

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 超臨界流体クロマトグラフィーを用いた疎水性代謝物の分離分析2007

    • Author(s)
      馬場健史, 福崎英一郎
    • Journal Title

      J. Mass Spectrom. Soc. Jpn 55

      Pages: 193-199

    • NAID

      10019487518

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] メタボロミクス(代謝物総体解析)の原理と食品工学への応用2007

    • Author(s)
      福崎英一郎, 馬場健史
    • Journal Title

      FFIジャーナル 212

      Pages: 380-388

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 植物細胞の環境ストレス応答の分子機構2007

    • Author(s)
      吉田和哉, ら
    • Journal Title

      一細胞定量解析の最前線

      Pages: 112-12

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 植物における抗体医薬生産2007

    • Author(s)
      松井健史, ら
    • Journal Title

      抗体医薬の最前線

      Pages: 226-235

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Dynamic Processes in endocytic transformation of a raft-exhibitinggiant liposome"2007

    • Author(s)
      T. Hamada, Y. Miura, K. Ishii, S. Araki, K. Yoshikawa, M. Vestergaard, M. Takagi
    • Journal Title

      J. Phys. Chem. B 111

      Pages: 10853-10857

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Systematic analysis of aggregates from 38 kinds of non disease-related proteins: identifying the intrinsic propensity of polypeptides to form amyloid fibrils.2007

    • Author(s)
      Y. Aso, K. Shiraki, M. Takagi
    • Journal Title

      Biosci. Biotechnol. Biochem. 71

      Pages: 1313-1321

    • NAID

      10027514990

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Real-time monitoring of dynamic intracellular Ca (2+) movement during early embryogenesis through expression2007

    • Author(s)
      Y. Tsuruwaka, T. Konishi, A. Miyawaki, M. Takagi
    • Journal Title

      Zebrafish 4

      Pages: 253-260

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 生体モデル膜ラフトドメインの動的構造2007

    • Author(s)
      浜田勉、高木昌宏
    • Journal Title

      化学と生物 45

      Pages: 436-438

    • NAID

      130004808831

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Two-dimensional HPLC on-line analysis of phosphopeptides using titania and monolithic columnc.2006

    • Author(s)
      Hata K, Morisaka H, Ishizuka N, Ueda M.
    • Journal Title

      Anal Biochem 350

      Pages: 191-197

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two-demensional HPLC on-line analysis of phosphopeptides using titania and monolithic columns2006

    • Author(s)
      K.Hata, M.Ueda et al.
    • Journal Title

      Anal. Biochem. 350・2

      Pages: 292-297

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Enhanced sequence coverage in tryptic fragment analysis by two-dimensional HPLC/MS using a monolithic column2006

    • Author(s)
      H.Morisaka, M.Ueda et al.
    • Journal Title

      Biosci. Biotechnol. Biochem. 70・9

      Pages: 2154-2159

    • Related Report
      2006 Annual Research Report
  • [Journal Article] N(15)-enrichment of metabolites in suspension cultured cells and its application to metabolomics2006

    • Author(s)
      K.Harada, E.Fukusaki et al.
    • Journal Title

      Biotechnol. Prog. 22・4

      Pages: 1003-1011

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Enhancing the tolerance of zebrafish to heavy metal toxicity by plant phytochelatin synthase2006

    • Author(s)
      T.Konishi, M.Takagi et al.
    • Journal Title

      J. Biotechnol. 122

      Pages: 316-325

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Quantitative and dynamic analyses of G protein-coupled receptor signaling in yeast2006

    • Author(s)
      J.Ishii, A.Kondo et al.
    • Journal Title

      Biotechnol. Prog. 22・4

      Pages: 954-960

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Photoimmobilization for microarrays2006

    • Author(s)
      Y.Ito
    • Journal Title

      Biotechnol. Prog. 22・4

      Pages: 924-932

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Detection of protein-protein interactions by a combination of a novel cytoplasmic membrane targeting system of recombinant proteins and fluorescence resonance energy transfer (FRET).2006

    • Author(s)
      S.Shbasaki et al.
    • Journal Title

      Appl.Microbiol.Biotechnol. (in press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Metabolic fingerprinting and profiting of Arabidopsis thaliana leaf and its cultured cells T87 by GC/MS.2006

    • Author(s)
      T.Fukusaki et al.
    • Journal Title

      Z Naturforsch [C] (in press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Enhancing the tolerance of zebrafish (Danio rerio) to heavy metal toxicity by the expression of plant phytochelatin synthase.2006

    • Author(s)
      T.Konishi et al.
    • Journal Title

      J.Biotechnol. 122

      Pages: 316-325

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Construction of novel single cell screening system using a yeast cell chip for nano-sized modified-protein-displaying libraries.2005

    • Author(s)
      T.Fukuda et al.
    • Journal Title

      Nanobiotechnology 1

      Pages: 105-111

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Stable isotope dilution-based accurate comparative quantification of nitrogen-containing metabolites in Arabidopsis thaliana T87 cells using in vivo 15N-isotope enrichment.2005

    • Author(s)
      J.K.Kim et al.
    • Journal Title

      Biosci.Biotechnol.Biochem. 69

      Pages: 1331-1340

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Stretched-exponential analysis of heat-induced aggregation of apo-concanavalin A.2005

    • Author(s)
      M.Kudo et al.
    • Journal Title

      Protein J. 24

      Pages: 193-199

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Characterisation of a New Fluorogenic Substrate for Microsomal Glutathione Transferase 1

    • Author(s)
      Johan Alander, Katarina Johansson, Vanina Dahlstrom Heuser, Henny Farebo, Julia Jarvliden, Hiroshi Abe, Aya Shibata, Mika Ito, Yoshihiro Ito, Ralf Morgenstern
    • Journal Title

      Anal Biochem (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] モノリス型カラムを用いたプロテオーム解析システムの構築2009

    • Author(s)
      森坂裕信, 植田充美
    • Organizer
      日本農芸化学会2009大会
    • Place of Presentation
      福岡マリンメッセ
    • Year and Date
      2009-03-28
    • Related Report
      2008 Final Research Report
  • [Presentation] LC/IT-TOF-MSによる定量的microRNA解析手法の開発2009

    • Author(s)
      瀧村晋、和泉自泰、馬場健史、福崎英一郎
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      福岡市
    • Year and Date
      2009-03-28
    • Related Report
      2008 Final Research Report
  • [Presentation] Quantitative analysis of signal transduction2008

    • Author(s)
      Hara K, Morisaka H, Ueda M
    • Organizer
      The 3rd International Workshop on Approaches to Single-Cell Analysis
    • Place of Presentation
      Zurich, Switzerland
    • Year and Date
      2008-09-13
    • Related Report
      2008 Final Research Report
  • [Presentation] Domain-Mediated Endocytic Budding in a Raft-Exhibiting Giant Liposome2008

    • Author(s)
      T. Hamada, et.al.
    • Organizer
      3rd International Workshop on Approaches to Single-Cell Analysis
    • Place of Presentation
      ETH Center, Zurich, Switzerland
    • Year and Date
      2008-09-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] モノリスカラムを用いたHPLCによるプロテオーム解析2008

    • Author(s)
      森坂裕信, 植田充美
    • Organizer
      第21回バイオメデイカル分析科学シンポジウム
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2008-08-05
    • Related Report
      2008 Final Research Report
  • [Presentation] ゼブラフィッシュDAX1遺伝子の機能解析2008

    • Author(s)
      矢島好文
    • Organizer
      日本水産学会春季大会
    • Place of Presentation
      東海大学海洋学部キャンパス
    • Year and Date
      2008-03-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] 非対称2分子膜リポソームの構築2008

    • Author(s)
      小松佑規、三浦陽子、浜田勉、高木昌宏
    • Organizer
      日本化学会第88春季年会
    • Place of Presentation
      立教大学池袋キャンパス
    • Year and Date
      2008-03-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] リン脂質の構造に依存した膜小胞動態2008

    • Author(s)
      川口耕平、石井健一、浜田勉、高木昌宏
    • Organizer
      日本化学会第88春季年会
    • Place of Presentation
      立教大学池袋キャンパス
    • Year and Date
      2008-03-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] 細胞膜脂質ラフトドメインの安定性の評価2008

    • Author(s)
      山口健太朗、鈴木えり子、浜田勉、高木昌宏
    • Organizer
      日本化学会第88春季年会
    • Place of Presentation
      立教大学池袋キャンパス
    • Year and Date
      2008-03-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高速・高性能プロテオーム解析のためのシリカモノリス型カラムの開発2008

    • Author(s)
      森坂裕信, ら
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋 名城大学
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] エリスリトールによる植物生育促進作用の2D-HPLCシステムを用いたプロテオーム解析2008

    • Author(s)
      小林謙吾, ら
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋 名城大学
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] ゼブラフィッシュのメタボローム解析2008

    • Author(s)
      吉田 真子, ら
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋 名城大学
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 出芽酵母寿命関連変異株のメタボローム解析2008

    • Author(s)
      吉田 亮, ら
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋 名城大学
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 植物ホルモン類の網羅的高感度LC-ESI-MS/MS分析2008

    • Author(s)
      和泉 自泰, ら
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋 名城大学
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] CE/MSを用いた一次代謝物の安定同位体標識率モニタリング法の開発2008

    • Author(s)
      大山 陽子, ら
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋 名城大学
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] ニチニチソウのメチルジャスモン酸応答に関する15N標識率解析2008

    • Author(s)
      原田 和生, ら
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋 名城大学
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脂質膜相分離ドメインの内胞ダイナミクス2008

    • Author(s)
      浜田勉、高木昌宏、三浦陽子
    • Organizer
      日本物理学会 第63回年次大会
    • Place of Presentation
      近畿大学
    • Year and Date
      2008-03-23
    • Related Report
      2007 Annual Research Report
  • [Presentation] フローサイトメーター(FCM)を利用した酵母GPCRシグナリング解析技術2008

    • Author(s)
      石井純, ら
    • Organizer
      化学工学会
    • Place of Presentation
      浜松 静岡大学
    • Year and Date
      2008-03-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Domain-Mediated Endocytic Buddingin a Raft Model Membrane2008

    • Author(s)
      T. Hamada, Y. Miura, S. Araki, K. Yoshikawa, M. Takagi
    • Organizer
      International Workshop on "Physical Phenomena in Multi-Component Membranes"
    • Place of Presentation
      首都大学 東京
    • Year and Date
      2008-03-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] 酵母PCAシステムによるタンパク質分子間相互作用の検出2008

    • Author(s)
      坂田梢, ら
    • Organizer
      化学工学会学生発表会
    • Place of Presentation
      吹田 関西大学
    • Year and Date
      2008-03-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] 中度好塩性細菌Halomonas elongata OUT30018株における銅応答遺伝子の発現解析2008

    • Author(s)
      仲山英樹, ら
    • Organizer
      ゲノム微生物学会年会
    • Place of Presentation
      大阪大学
    • Year and Date
      2008-03-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] 塩類集積環境の金属浄化に有用なセルフクローニング型アーミングHalomonas elongataの作製2008

    • Author(s)
      河目裕介, ら
    • Organizer
      ゲノム微生物学会年会
    • Place of Presentation
      大阪大学
    • Year and Date
      2008-03-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] Dynamic movement of raft-exhibiting giant liposome2008

    • Author(s)
      M. Takagi, T. Hamada (Invited)
    • Organizer
      Swedish-Japanese workshop in Biotechnology
    • Place of Presentation
      Alba Nova University Center, RoyalInstitute of Technology, Stockholm
    • Year and Date
      2008-02-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] 酵母GPCRシグナリングにおけるフローサイトメトリー解析技術2008

    • Author(s)
      石井純, ら
    • Organizer
      最先端バイオテクノロジー若手発表会
    • Place of Presentation
      西宮 神戸女学院大学
    • Year and Date
      2008-02-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脂質膜ラフトドメインのエンドサイトーシス機構2008

    • Author(s)
      浜田勉、高木昌宏、三浦陽子
    • Organizer
      ソフトマター物理・第2回公開シンポジウム
    • Place of Presentation
      名古屋大学
    • Year and Date
      2008-01-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] 生体モデル膜ラフトドメインのエンドサイトーシス2007

    • Author(s)
      浜田勉、高木昌宏、三浦陽子
    • Organizer
      日本生物物理学会第45回年次大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] 生体模倣非対称モデル膜におけるドメイン構造形成2007

    • Author(s)
      三浦陽子、小松佑規、浜田勉、高木昌宏
    • Organizer
      日本生物物理学会第45回年次大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] 光による脂質二分子膜小胞の形態転移2007

    • Author(s)
      石井健一、長崎健、浜田勉、高木昌宏
    • Organizer
      日本生物物理学会第45回年次大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] 分子ディスプレイ法によるタンパク質の同時生産/回収システムの構築2007

    • Author(s)
      芝崎誠司, ら
    • Organizer
      日本分子生物学会年会・日本生化学会大会・合同大会
    • Place of Presentation
      横浜 横浜パシフィコ
    • Year and Date
      2007-12-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] 好塩性徴生物のゲノム情報から環境技術へ2007

    • Author(s)
      仲山英樹, ら
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      横浜 横浜パシフィコ
    • Year and Date
      2007-12-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] イネの根におけるカリウムイオン輸送体HAKの発現と機能2007

    • Author(s)
      岡田知之, ら
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      横浜 横浜パシフィコ
    • Year and Date
      2007-12-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] 代謝物フィンガープリンティングの技術開発と応用2007

    • Author(s)
      福崎英一郎
    • Organizer
      北陸質量分析談話会
    • Place of Presentation
      北陸大学薬学部
    • Year and Date
      2007-12-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] 光による脂質二分子膜小胞形態のコントロール2007

    • Author(s)
      石井健一、畠山剛臣、長崎 健、浜田勉、高木昌宏
    • Organizer
      第一回 サポーティッドメンブレンワークショップ
    • Place of Presentation
      蒲郡温泉
    • Year and Date
      2007-11-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] ワイドポアシリカモノリス型カラムを用いたプロテオーム解析2007

    • Author(s)
      森坂裕信, 植田充美
    • Organizer
      第18回クロマトグラフィー科学会議
    • Place of Presentation
      函館市民会館
    • Year and Date
      2007-11-11
    • Related Report
      2008 Final Research Report
  • [Presentation] 人工透析アミロイドーシスにおける血中プロテアーゼの影響2007

    • Author(s)
      塩野入純平、浜田勉、高木昌宏
    • Organizer
      日本化学会近畿支部北陸地区研究発表会
    • Place of Presentation
      金沢大学(角間キャンパス)自然科学本館
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] 細胞膜ラフトドメインの動的構造と安定性2007

    • Author(s)
      鈴木えり子、山口健太郎、浜田勉、高木昌宏
    • Organizer
      日本化学会近畿支部北陸地区研究発表会
    • Place of Presentation
      金沢大学(角間キャンパス)自然科学本館
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] 可溶化過程における脂質二分子膜の膜揺動2007

    • Author(s)
      平林祐一、浜田勉、高木昌宏
    • Organizer
      日本化学会近畿支部北陸地区研究発表会
    • Place of Presentation
      金沢大学(角間キャンパス)自然科学本館
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脂質ラフトミクロドメインとAβの相互作用2007

    • Author(s)
      谷川晋一、Munde Vestagaard、浜田勉、高木昌宏
    • Organizer
      日本化学会近畿支部北陸地区研究発表会
    • Place of Presentation
      金沢大学(角間キャンパス)自然科学本館
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] 生体模倣モデル膜におけるドメイン構造形成2007

    • Author(s)
      三浦陽子、小松佑規、浜田勉、高木昌宏
    • Organizer
      日本化学会近畿支部北陸地区研究発表会
    • Place of Presentation
      金沢大学(角間キャンパス)自然科学本館
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] ワイドポアシリカモノリス型カラムを用いたプロテオーム解析2007

    • Author(s)
      森坂裕信, ら
    • Organizer
      クロマトグラフィー科学会議
    • Place of Presentation
      函館 市民会館
    • Year and Date
      2007-11-09
    • Related Report
      2007 Annual Research Report
  • [Presentation] Photolithography using Novel Photo-Reactive Natural and Synthetic Polmers2007

    • Author(s)
      Ito Y
    • Organizer
      CNP-2007
    • Place of Presentation
      Kerala
    • Year and Date
      2007-11-07
    • Related Report
      2008 Final Research Report
  • [Presentation] 代謝物フィンガープリンティングの技術開発と応用2007

    • Author(s)
      福崎英一郎
    • Organizer
      メタボロームシンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      2007-11-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] Photo-induced transformation in cell-sized lipid vesicles2007

    • Author(s)
      石井健一、長崎健、浜田勉、高木昌宏
    • Organizer
      1st International Symposium on Ultimate Stability of Nano-structured Polymers and Composites
    • Place of Presentation
      石川ハイテク交流センター国際会議場
    • Year and Date
      2007-10-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Potassium and sodium ions transport system in rice" JSPS Colloquium on Frontiers of Plant Biotechnology2007

    • Author(s)
      K. Yoshida
    • Organizer
      Plant Biotechnology
    • Place of Presentation
      Stockholm, Stockholm University
    • Year and Date
      2007-10-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] Expression and function of HAK potassium ion transporters in root of rice2007

    • Author(s)
      T. Okada, et. al.
    • Organizer
      Plant Biotechnology
    • Place of Presentation
      Stockholm, Stockholm University
    • Year and Date
      2007-10-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] スルホン化キャピラリーを用いたキャピラリー電気泳動/質量分析計によるアニオン性代謝産物プロファイリング法の開発2007

    • Author(s)
      原田和生, ら
    • Organizer
      日本生物工学
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] ニチニチソウのメチルジャスモン酸応答に関するメタボローム解析2007

    • Author(s)
      田伏哲也, ら
    • Organizer
      日本生物工学会
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] ゼブラフィッシュのメタボローム解析2007

    • Author(s)
      林俊介, ら
    • Organizer
      日本生物工学会
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 出芽酵母寿命関連変異株のメタボローム解析2007

    • Author(s)
      吉田亮, ら
    • Organizer
      日本生物工学会
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] ハロモナス細胞表層ディスプレイシステムを用いた高塩環境浄化に有用な金属結合ドメインの探索2007

    • Author(s)
      仲山英樹, ら
    • Organizer
      日本生物工学会
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 中度好塩性細菌Halomonas elongate OUT30018株における金属応答遺伝子の発現解析2007

    • Author(s)
      古賀愛弓, ら
    • Organizer
      日本生物工学会
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脂質二分子膜可熔化プロセスにおける膜揺動ダイナミクス2007

    • Author(s)
      平林祐一、浜田勉、高木昌宏
    • Organizer
      日本生物工学会
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 細胞膜脂質ラフトドメインの安定性評価2007

    • Author(s)
      山口健太朗、鈴木えり子、浜田勉、高木昌宏
    • Organizer
      日本生物工学会
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脂質二分子膜形態の光制御2007

    • Author(s)
      石井健一、長崎健、浜田勉、高木昌宏
    • Organizer
      日本生物工学会
    • Place of Presentation
      広島大学
    • Year and Date
      2007-09-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 酵母を用いたリガンド検出システムの開発2007

    • Author(s)
      森口みゆき, ら
    • Organizer
      化学工学会
    • Place of Presentation
      札幌 北海道大学
    • Year and Date
      2007-09-13
    • Related Report
      2007 Annual Research Report
  • [Presentation] Screening of zebrafish genes involved in morphogenesisusing human siRNA library2007

    • Author(s)
      M. Takagi, Tomio Yamauchi, Yoshifumi Yajima (invited)
    • Organizer
      The 6th international forum on post-genome technologies
    • Place of Presentation
      Bamboo Grove Hotel, Suzhou, China
    • Year and Date
      2007-09-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Screening of zebrafish genes involved in morphogenesisusing human siRNA library2007

    • Author(s)
      M. Takagi
    • Organizer
      The second international workshop on approaches to single-cell analysis
    • Place of Presentation
      Waseda University, Japan
    • Year and Date
      2007-09-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] 脂質2分子膜小胞の光による形態のスイッチング2007

    • Author(s)
      浜田勉、石井健一、長崎健、高木昌宏
    • Organizer
      第10回バイオテクノロジー部会シンポジウム
    • Place of Presentation
      早稲田大学
    • Year and Date
      2007-09-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] 巨大リポソーム上ラフトドメインの出芽ダイナミクス2007

    • Author(s)
      浜田 勉、高木昌宏
    • Organizer
      第1回ソフトマター物理若手勉強会
    • Place of Presentation
      宮島ホテル まこと
    • Year and Date
      2007-08-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] Endoplasmic reticulum stress responses as criteria to evaluate functional foods and cosmetics2007

    • Author(s)
      M. Takagi, K. Yamaguchi, T. Hamada (Invited)
    • Organizer
      The 6th World Congress on Alternatives and Animal Use in the Life Sciences
    • Place of Presentation
      Hotel East 21 Tokyo, Japan
    • Year and Date
      2007-08-25
    • Related Report
      2007 Annual Research Report
  • [Presentation] 生体モデル膜ドメインの出芽ダイナミクス2007

    • Author(s)
      浜田勉、高木昌宏、三浦陽子
    • Organizer
      ソフトマター物理・第2回領域研究会
    • Place of Presentation
      米沢市 伝国の杜
    • Year and Date
      2007-06-22
    • Related Report
      2007 Annual Research Report
  • [Presentation] リポソーム形態の光スイッチング2007

    • Author(s)
      浜田勉、石井健一、長崎健、高木昌宏
    • Organizer
      日本膜学会第29年会
    • Place of Presentation
      東京理科大
    • Year and Date
      2007-05-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] フェロモン応答性タンパク質を利用した新規レポーターによるリガンド検出システムの開発2006

    • Author(s)
      森口みゆき, 石井純, 立松健司, 黒田俊一, 福田秀樹, 近藤昭彦
    • Organizer
      化学工学会第38回秋季大会
    • Place of Presentation
      福岡市
    • Year and Date
      2006-09-11
    • Related Report
      2008 Final Research Report
  • [Presentation] Imaging of intracellular calcium ion during embryogenesis of zebrafish.2006

    • Author(s)
      Takagi, M
    • Organizer
      The First International Workshop on Approaches to Single-cell Analysis
    • Place of Presentation
      Uppsala Sweden
    • Year and Date
      2006-06-06
    • Related Report
      2008 Final Research Report
  • [Book] ナノバイオテクノロジー : 新しいマテリアル、プロセスとデバイス2009

    • Author(s)
      植田充美
    • Publisher
      シーエムシー出版
    • Related Report
      2008 Final Research Report
  • [Book] 第2世代バイオ燃料の開発と応用展開2009

    • Author(s)
      蓮沼誠久, ら
    • Publisher
      シーエムシー出版(印刷中)
    • Related Report
      2008 Annual Research Report
  • [Book] 抗体医薬の最前線2007

    • Author(s)
      植田充美
    • Publisher
      シーエムシー出版
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Book] ナノバイオ事典2007

    • Author(s)
      山根恒夫, ら
    • Total Pages
      635
    • Publisher
      テクノシステム
    • Related Report
      2007 Annual Research Report
  • [Book] メタボロミクスの先端技術と応用2007

    • Author(s)
      福崎英一郎
    • Total Pages
      300
    • Publisher
      シーエムシー出版
    • Related Report
      2007 Annual Research Report
  • [Book] マイクロアレイ・バイオチップの最前線2007

    • Author(s)
      伊藤嘉浩
    • Total Pages
      305
    • Publisher
      シーエムシー出版
    • Related Report
      2007 Annual Research Report
  • [Book] 一細胞定量解析の最前線 -ライフサーベイヤ構築に向けて-2006

    • Author(s)
      神原秀記, 松永是, 植田充美
    • Publisher
      シーエムシー出版
    • Related Report
      2008 Final Research Report
  • [Book] -細胞定量解析の最前線ーライフサーベイヤ構築に向けて-2006

    • Author(s)
      神原秀記, 松永是, 植田充美
    • Total Pages
      272
    • Publisher
      シーエムシー出版
    • Related Report
      2006 Annual Research Report
  • [Remarks] 2007年2月5日 日刊工業新聞先端技術(芽を育む研究室)(北陸先端科学技術大学院大学・高木昌宏)

    • Related Report
      2008 Final Research Report
  • [Patent(Industrial Property Rights)] 細胞内チオール検出プローブ2008

    • Inventor(s)
      阿部洋, ら
    • Industrial Property Rights Holder
      理研
    • Industrial Property Number
      2008-049464
    • Filing Date
      2008-02-29
    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] 小胞体ストレス関与物質のスクリーニング方法等2006

    • Inventor(s)
      高木 昌宏ら
    • Industrial Property Rights Holder
      北陸先端大ら
    • Industrial Property Number
      2006-320650
    • Filing Date
      2006-11-28
    • Related Report
      2006 Annual Research Report

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Published: 2005-04-01   Modified: 2018-03-28  

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