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Concept and Development of The Optically Driven Nanomechatronics

Research Project

Project/Area Number 17206023
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionNagoya University

Principal Investigator

IKUTA Kouji  Nagoya University, Graduate School of Engineering, Professor, 大学院工学研究科, 教授 (90212745)

Co-Investigator(Kenkyū-buntansha) KATO Takashi  Nagoya University, Graduate School of Engineering, Assistant Professor, 大学院工学研究科, 助手 (90362285)
OTA Yusuke  Nagoya University, Graduate School of Engineering, Assistant Professor, 大学院工学研究科, 助手 (20367311)
IKEUCHI Masashi  Nagoya University, Graduate School of Engineering, COE Researcher, 大学院工学研究科, COE研究員 (90377820)
HASEGAWA Tadahiro  Osaka Institute of Technology, Dept. of Mechanical Engineering, Associate professor, 工学部, 助教授 (10340605)
NARUSE Keiji  Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Professor, 医歯薬学総合研究科, 教授 (40252233)
山田 章  名古屋大学, 工学研究科, COE研究員 (20377815)
Project Period (FY) 2005 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥50,700,000 (Direct Cost: ¥39,000,000、Indirect Cost: ¥11,700,000)
Fiscal Year 2006: ¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2005: ¥31,460,000 (Direct Cost: ¥24,200,000、Indirect Cost: ¥7,260,000)
KeywordsMicro stereolithography / Two-photon high-speed stereolithography / Photo-curable resin / Laser Trapping / MEMS / Remote Control / Optical Drive / Biocompatibility / マイクロ光造形 / 2光子高速造形法
Research Abstract

We have proposed and developed "Optically driven nanomechatronics", which uses only optical energy to drive micro/nano machines. As the concept is totally different from conventional micro/nano actuators, we have started from the basics, and finally completed a prototype system of the world's first micro-robot driven by laser trapping in water.
1) Concept of "Optically driven nanomechatronics"
In conventional researches of micro/nano machines, both the mechanical components and the electrical lead wires should be miniaturized. On the contrary, optically driven micro/nano machines need only mechanical components to be miniaturized. The mechanical components are made of transparent materials, and driven by laser trapping technique from a distance. The micro/nano machine itself has no electrical lead wires in it. Therefore, the micro/nano machine becomes easier to be fabricated, and has more flexibility in design. Moreover, the micro/nano machine can work both in air and in liquid for biolo … More gical applications.
2) Fabrication Method
We have fabricated the micro/nano machines with 100nm resolution using "2-photon high-speed micro stereo-lithography" originally developed in our group. For the smooth manipulation of the micro/nano machines in liquid, we applied biological coating method to prevent adhesion between mechanical components. Several types of micro manipulators 5-10μm in length with multi degrees of freedom were successfully fabricated on a thin glass substrate.
3) Verification
The micro manipulators were successfully actuated with IR laser at more than 10Hz in water.
4) Remote Control System
A micro manipulator with 3 degrees of freedom-grip, rotation and translation, was remotely controlled with an originally developed joystick-like controller while observing the manipulator through an inverted microscope. Single cell manipulation and the measurement of cell elasticity were successfully achieved in water solution.
In this project, we have established the basics of "optically driven nanomechatronics", and demonstrated its wide potential for applications in both biological and non-biological fields. Less

Report

(3 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • Research Products

    (113 results)

All 2007 2006 2005 Other

All Journal Article (104 results) Book (5 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] 低侵襲手術用サージェリレコーダの開発と動物実験による機能検証2007

    • Author(s)
      生田幸士, 加藤大香士, 大栄広樹, 篠原一彦
    • Journal Title

      生体医工学 45(1)(印刷中)

    • NAID

      110006381540

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] 多分岐切換用ロータリー型マイクロバルブチップ(第1報)ロータリー機構を利用した多分岐切換原理の実証2007

    • Author(s)
      長谷川忠大, 中嶋健一郎, 生田幸士
    • Journal Title

      日本機械学会論文集C編 73 (727)

      Pages: 811-816

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 全工程微量サンプル蛋白分析用化学ICチップ群の開発2007

    • Author(s)
      生田幸士, 佐竹宣彦, 大橋竜也, 柴田真由子
    • Journal Title

      生体医工学 44(4)(印刷中)

    • NAID

      110006381542

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Takashi Kato, Hiroki Ooe and Kazuhiko Shinohara, Development of Surgery Recorder System for Minimally Invasive Surgery2007

    • Author(s)
      Koji Ikuta
    • Journal Title

      Trans. JSMBE 45(1), (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 多分岐切換用ロータリ形マイクロバルブチップ(第1報,ロータリ機構を利用した多分岐切換原理の実証)2007

    • Author(s)
      Tadahiro Hasegawa, Kenichiro Nakajima, Koji Ikuta
    • Journal Title

      Trans. JSME C 73(727)

      Pages: 811-816

    • NAID

      110006271403

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] New Biochemical IC chips for Overall Protein Analysis with micro sampling2007

    • Author(s)
      Koji Ikuta, Nobuhiko Satake, Tatsuya Ohashi, Mayuko Shibata
    • Journal Title

      Trans. JSMBE 44(4), (in press)

    • NAID

      10021287454

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 多分岐切換用ロータリー型マイクロバルブチップ(第1報)ロークリー機構を利用した多分岐切換原理の実証2007

    • Author(s)
      長谷川忠大, 中嶋健一郎, 生田幸士
    • Journal Title

      日本機械学会論文集 C編 73 (727)

      Pages: 811-816

    • Related Report
      2006 Annual Research Report
  • [Journal Article] ポリマー薄膜を用いた三次元マイクロ流路デバイスの研究-再生医療のための人工毛細血管の開発2006

    • Author(s)
      池内真志, 生田幸士
    • Journal Title

      日本コンピュータ外科学会誌 17・4

      Pages: 587-592

    • NAID

      10021286894

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Viscoelastic and dynamic nonlinear properties of airway smooth muscle tissue : roles of mechanical force and the cytoskeleton2006

    • Author(s)
      S.Ito, A.Majumdar, H.Kume, K.Shimokata, K.Naruse, K.R.Lutchen, D.Stamenovic, B.Suki
    • Journal Title

      American Journal of Physiology 290 (6)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Bi-phasic activation of eNOS in response to uni-axial cyclic stretch is mediated by differential mechanisms in BAECs2006

    • Author(s)
      H.Takeda, K.Komori, N.Nishikimi, Y.Nimura, M.Sokabe, K.Naruse
    • Journal Title

      Life Sciences 79 (3)

      Pages: 233-239

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle2006

    • Author(s)
      S.Ito, H.Kume, T.Oguma, Y.Ito, M.Kondo, K.Shimokata, B.Suki, K.Naruse
    • Journal Title

      European Journal of Pharmacology 15;552(1-3)

      Pages: 135-142

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 特集医療・福祉用ロボットの現状と将来展望「未来医療を進化させる新原理バイオロボティクス」2006

    • Author(s)
      生田幸士
    • Journal Title

      金属 76・1

      Pages: 9-11

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 新原理マイクロ・ナノマシンによる未来医療-化学ICとバイオロボットの夢-2006

    • Author(s)
      生田幸士
    • Journal Title

      未来医療 21

      Pages: 44-48

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] 特集愛・地球博のロボット『遠隔微細手術ロボット「マイクロフィンガー・ハイパーフィンガー」』2006

    • Author(s)
      生田幸士
    • Journal Title

      日本ロボット学会誌 24・2

      Pages: 38-38

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Multi-degree of Freedom Hydraulic Pressure Driven Safety Active Catheter2006

    • Author(s)
      K.Ikuta, H.Ichikawa, K.Suzuki, D.Yajima
    • Journal Title

      Proc. 2006 IEEE International Conference on Robotics and Automation (ICRA' 06)

      Pages: 4161-4166

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Hydrodynamic Active Catheter with Multi Degrees of Freedom Motion2006

    • Author(s)
      K.Ikuta, D.Yajima, H.Ichikawa, K.Suzuki
    • Journal Title

      IFMBE Proceedings 14

      Pages: 2968-2971

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Development of Surgery Recorder System for Minimally Invasive Surgery2006

    • Author(s)
      K.Ikuta, T.Kato, S.Ando, H.Ooe
    • Journal Title

      IFMBE Proceedings 14

      Pages: 2955-2958

    • NAID

      110006381540

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] The Membrane Micro Emboss (MeME) Process for Fabricating 3-D Microfluidic Device Formed from Thin Polymer Membrane2006

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Proc. μTAS' 06 Conference Tokyo

      Pages: 693-695

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] On-site Size-selective Particle Sampling Using Mesoporous Polymer Membrane Microfluidic Device2006

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Proc. μTAS' 06 Conference Tokyo

      Pages: 1169-1171

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] AIR PRESSURE TYPE MICRO DISPENSER SYSTEM WITHOUT ANY DEAD VOLUME FOR PORTABLE MICRO CHEMICAL DEVICE2006

    • Author(s)
      Tadahiro Hasegawa, Fumiyuki Omatsu, Toshiyuki Tsuji, Koji Ikuta
    • Journal Title

      Proc. μTAS' 06 Conference Tokyo

      Pages: 1112-1114

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] Three-dimensional Microfabrication for Biodegradable Polymers Toward Implantable Micro Devices2006

    • Author(s)
      Akira Yamada, Fuminori Niikura, Koji Ikuta
    • Journal Title

      Proc. μTAS' 06 Conference Tokyo

      Pages: 684-686

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] バイオ化学ICチップと反応観測制御システム2006

    • Author(s)
      生田幸士
    • Journal Title

      電気情報通信学会誌 89・5

      Pages: 411-418

    • NAID

      110004735703

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] 新原理マイクロ・ナノデバイスによる人工臓器研究-光で作って光で動かすナノマシンとバイオ化学ICチップ2006

    • Author(s)
      生田幸士
    • Journal Title

      第43回日本人工臓器学会大会予稿集

      Pages: 13-18

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] 名物研究者からの未来の研究者へのメッセージ2006

    • Author(s)
      生田幸士
    • Journal Title

      ロボコンマガジン 49

      Pages: 122-124

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Journal Article] roles of mechanical force and the cytoskeleton2006

    • Author(s)
      S.Ito, A.Majumdar, H.Kume, K.Shimokata, K.Naruse, K.R.Lutchen, D.Stamenovic, B.Suki, Viscoelastic, dynamic nonlinear properties of airway smooth muscle tissue
    • Journal Title

      American Journal of Physiology 290(6)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Bi-phasic activation of eNOS in response to uni-axial cyclic stretch is mediated by differential mechanisms in BAECs2006

    • Author(s)
      H.Takeda, K.Komori, N.Nishikimi, Y.Nimura, M.Sokabe, K.Naruse
    • Journal Title

      Life Sciences 79(3)

      Pages: 233-239

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Novel Biorobotics for Evolution of Future Medicine2006

    • Author(s)
      Koji Ikuta
    • Journal Title

      Kinzoku 76・1

      Pages: 9-11

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Future Medicine Realized by Novel Micro/Nano Machine-Chemical IC and Biorobot-2006

    • Author(s)
      Koji Ikuta
    • Journal Title

      Future Medicine 21

      Pages: 44-48

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Robots in Expo2005 "Micro Finger and Hyper Finger for Remote Micro-surgery"2006

    • Author(s)
      Koji Ikuta
    • Journal Title

      Journal of RSJ. 24・2

      Pages: 38-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The Membrane Micro Emboss (MeME) Process for Fabricating 3-D Microfluidic Device Formed from Thin Polymer Membrane2006

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Proc. μTAS'06 Conference Tokyo

      Pages: 696-695

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Koji Ikuta On-site Size-selective Particle Sampling Using Mesoporous Polymer Membrane Microfluidic Device2006

    • Author(s)
      Masashi Ikeuchi
    • Journal Title

      Proc. μTAS'06 Conference Tokyo

      Pages: 1169-1171

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Air Pressure Type Micro Dispenser System without any Dead Volume for Portable Micro Chemical Device2006

    • Author(s)
      Tadahiro Hasegawa, Fumiyuki Omatsu, Toshiyuki Tsuji, Koji Ikuta
    • Journal Title

      Proc. μTAS'06 Conference Tokyo

      Pages: 1112-1114

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Three-dimensional Microfabrication for Biodegradable Polymers Toward Implantable Micro Devices2006

    • Author(s)
      Akira Yamada, Fuminori Niikura, Koji Ikuta
    • Journal Title

      Proc. μTAS'06 Conference Tokyo

      Pages: 684-686

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Biochemical IC Technologies for Future Biomedicine2006

    • Author(s)
      Koji Ikuta
    • Journal Title

      Journal of IEICE 89・5

      Pages: 411-418

    • NAID

      110004735703

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Message from established scientists to future scientists2006

    • Author(s)
      Koji Ikuta
    • Journal Title

      Robocon Magazine 49

      Pages: 122-124

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Koji Ikuta (Co-author)
    • Journal Title

      Iwanami Course on Robotics6-Robot Frontier 218

    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Koji Ikuta (Co-author)
    • Journal Title

      NGT, Handbook of laser processing 590

    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(欧文)」より2006

    • Author(s)
      Koji Ikuta (Co-author)
    • Journal Title

      Asakura, Denshi-bussei / Zairyo no Jiten 696

    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle2006

    • Author(s)
      S.Ito, H.Kume, T.Oguma, Y.Ito, M.Kondo, K.Shimokata, B.Suki, K.Naruse
    • Journal Title

      European Journal of Pharmacology 15;522(1-3)

      Pages: 135-142

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Three-dimensional Microfabrication for Biodegradable Polymers Toward Implantable Micro Devices2006

    • Author(s)
      22.Akira Yamada, Fuminori Niikura, Koji Ikuta
    • Journal Title

      Proc. μTAS' 06 Conference Tokyo

      Pages: 684-686

    • Related Report
      2006 Annual Research Report
  • [Journal Article] ポリマー薄膜を用いた三次元マイクロ流路デバイスの研究-再生医療のための人工毛細血管の開発2006

    • Author(s)
      池内真志, 生田幸士
    • Journal Title

      日本コンピュータ外科学会誌 17・4(印刷中)

    • NAID

      10021286894

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 特集 医療・福祉用ロボットの現状と将来展望「未来医療を進化させる新原理バイオロボティクス」2006

    • Author(s)
      生田幸士
    • Journal Title

      金属 76・1

      Pages: 9-11

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 特集 愛・地球博のロボット『遠隔微細手術ロボット「マイクロフィンガー・ハイパーフィンガー」』2006

    • Author(s)
      生田幸士
    • Journal Title

      日本ロボット学会誌 24・2

      Pages: 38-38

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 人工毛細血管のための生分解性薄膜微細流路成型法(MeME)の開発2005

    • Author(s)
      池内真志, 生田幸士
    • Journal Title

      生体医工学 43・4

      Pages: 646-652

    • NAID

      110004704978

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] Fabrication of reconfigurable protein matrices by cracking.2005

    • Author(s)
      Zhu, X., Mills, K.L., Peters, P.R., Bahng, J.H., Liu, E.H., Shim, J., Naruse, K., Csete, M.E., Thouless, M.D., Takayama, S.
    • Journal Title

      Nature Materials 4

      Pages: 403-406

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uni-axial continuous stretch2005

    • Author(s)
      Sasamoto, A., Nagino, M., Kobayashi, S., Naruse, K., Nimura, Y., Sokabe, M.
    • Journal Title

      Am J Physiol Cell Physiol. 288

      Pages: 1012-1022

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Stretch-induced cell proliferation is mediated by FAK-MAPK pathway.2005

    • Author(s)
      Wang, J.G., Miyazu, M., Sokabe, M., Naruse, K.
    • Journal Title

      Life Sci. 76

      Pages: 2817-2825

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] Activation of a Mechanosensitive BK Channel by Membrane Stress Created with Amphipaths2005

    • Author(s)
      Zhi Qi, Shaopeng Chi, Xueyan Su, Keiji Naruse, Masahiro Sokabe
    • Journal Title

      Molecular Membrane Biology 22

      Pages: 519-527

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] Fabrication of Polymer Membrane Microchannel by Membrane Micro Embossing (MeME)2005

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      CD-ROM Proc. of the International Conference on Bio-Nano-Informatics Fusion 2005 1

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Surgery Recorder for Minimally Invasive Surgery2005

    • Author(s)
      Koji Ikuta, Takashi Kato
    • Journal Title

      CD-ROM Proc. of the International Conference on Bio-Nano-Informatics Fusion 2005 1

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Real Three-dimensional Microfabrication for Biodegradable Polymers -Fabrication of microstructures with high-resolution and biocompatibility for implantable microdevices-2005

    • Author(s)
      A.Yamada, F.Niikura, K.Ikuta
    • Journal Title

      CD-ROM Proc. of the International Conference on Bio-Nano-Informatics Fusion 2005 1

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of Membrane Micro Embossing (MeME) Process for Self-Supporting Polymer Membrane Microchannel2005

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      DVD-ROM Proc. of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of the Surgery Recorder System2005

    • Author(s)
      Koji Ikuta, Takashi Kato
    • Journal Title

      DVD-ROM Proc. of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Three-dimensional Microfabrication System for Biodegradable Microdevices with High-resolution and Bio-applicability2005

    • Author(s)
      Koji Ikuta, Akira Yamada, Fuminori Niikura
    • Journal Title

      DVD-ROM Proc. of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of Free-Surface Microstereolithography with Ultra-High Resolution to Fabricate Hybrid 3-D Microdevices2005

    • Author(s)
      Kengo Kobayashi, Koji Ikuta
    • Journal Title

      Proc. of the 2005 International Symposium on Micro-Nano Mechatronics and Human Science (MHS2005) 05TH8845

      Pages: 273-278

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Hydraulic Pressure Drive with Multi-degrees of freedom Motion for Safety Active Catheter2005

    • Author(s)
      Koji Ikuta, Hironobu Ichikawa, Daisuke Yajima
    • Journal Title

      Proc. of the 2005 International Symposium on Micro-Nano Mechatronics and Human Science (MHS2005) 05TH8845

      Pages: 279-283

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Three-dimensional Microfabrication System Toward Advanced Biodegradable Implantable Devices2005

    • Author(s)
      Akira Yamada, Fuminori Niikura, Koji Ikuta
    • Journal Title

      CD-ROM Proc. of 2005 IEEE Workshop on Advanced Robotics and its Social Impacts (ARSO '05) 05EX1019C

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Real Three-dimensional Microfabrication for Biodegradable Polymers-Demonstration of microstructures with high-resolution and biocompatibility for implantable microdevices-2005

    • Author(s)
      Koji Ikuta, Akira Yamada, Fuminori Niikura
    • Journal Title

      CD-ROM Proc. of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The fully integrated cell-free protein synthesis system by biochemical IC chip-set2005

    • Author(s)
      Koji Ikuta, Tatsuya Ohashi, Kota Ikeda, Atsushi Takahashi, Nobuhiko Satake
    • Journal Title

      CD-ROM Proc. of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The Surgery Recorder System for Minimally Invasive Surgery - Concept, Prototype and Experimental Evaluation In-Vivo2005

    • Author(s)
      Koji Ikuta, Takashi Kato, Satoshi Ando, Hiroki Ooe
    • Journal Title

      CD-ROM Proc. of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] マイクロからナノ手術ロボティクスヘ2005

    • Author(s)
      生田幸士
    • Journal Title

      脳神経外科速報 15

      Pages: 1132-1136

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 一枚の写真2005

    • Author(s)
      生田幸士
    • Journal Title

      O PLUSE 27・5

      Pages: 479-480

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] 第6回耳鼻咽喉科ナビゲーション研究会「耳鼻咽喉領域をめざす医療マイクロロボットとバイオナノマシン」2005

    • Author(s)
      生田幸士
    • Journal Title

      耳鼻咽喉科展望 48・6

      Pages: 76-83

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Journal Article] Fabrication of Biodegradable Membrane Micro-channels for Artificial Blood Capillary Networks Using Membrane Micro Embossing (MeME)2005

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Trans. JSMBE 43・4

      Pages: 646-652

    • NAID

      110004704978

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Fabrication of reconfigurable protein matrices by cracking2005

    • Author(s)
      Zhu, X., Mills, K.L., Peters, P.R., Bahng, J.H., Liu, E.H., Shim, J., Naruse, K, Csete, M.E., Thouless, M.D., Takayama, S.
    • Journal Title

      Nature Materials 4

      Pages: 403-406

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Stretch-induced cell proliferation is mediated by FAK-MAPK pathway2005

    • Author(s)
      Wang, J.G., Miyazu, M., Sokabe, M., Naruse, K.
    • Journal Title

      Life Sciences 76

      Pages: 2817-2825

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Activation of a Mechanosensitive BK Channel by Membrane Stress Created with Amphipaths2005

    • Author(s)
      Zhi Qi, Shaopeng Chi, Xueyan Su, Keiji Naruse, Masahiro Sokabe
    • Journal Title

      Proc. of the International Conference on Bio-Nano-Informatics Fusion 2005 1(CD-ROM)

      Pages: 3-3

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Fabrication of Polymer Membrane Microchannel by Membrane Micro Embossing (MeME)2005

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Molecular Membrane Biology 22

      Pages: 519-527

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Surgery Recorder for Minimally Invasive Surgery2005

    • Author(s)
      Koji Ikuta, Takashi Kato
    • Journal Title

      Proc. of the International Conference on Bio-Nano-Informatics Fusion 2005 1(CD-ROM)

      Pages: 4-4

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Ikuta Real Three-dimensional Microfabrication for Biodegradable Polymers-Fabrication of microstructures with high-resolution and biocompatibility for implantable microdevices-2005

    • Author(s)
      A.Yamada, F.Niikura, K.
    • Journal Title

      Proc. of the International Conference on Bio-Nano-Informatics Fusion 2005 1(CD-ROM)

      Pages: 4-4

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of Membrane Micro Embossing (MeME) Process for Self-Supporting Polymer Membrane Microchannel2005

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Proc. of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D(DVD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Development of the Surgery Recorder System2005

    • Author(s)
      Koji Ikuta, Takashi Kato
    • Journal Title

      Proc. of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D(DVD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Three-dimensional Microfabrication System for Biodegradable Microdevices with High-resolution and Bio-applicability2005

    • Author(s)
      Koji Ikuta, Akira Yamada, Fuminori Niikura
    • Journal Title

      Proc. of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D(DVD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Three-dimensional Microfabrication System Toward Advanced Biodegradable Implantable Devices2005

    • Author(s)
      Akira Yamada, Fuminori Niikura, Koji Ikuta
    • Journal Title

      Proc. of 2005 IEEE Workshop on Advanced Robotics and its Social Impacts (ARSO '05) 05EX1019C(CD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Real Three-dimensional Microfabrication for Biodegradable Polymers-Demonstration of microstructures with high-resolution and biocompatibility for implantable microdevices-2005

    • Author(s)
      Koji Ikuta, Akira Yamada, Fuminori Niikura
    • Journal Title

      Proc. of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8(CD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The fully integrated cell-free protein synthesis system by biochemical IC chip-set2005

    • Author(s)
      Koji Ikuta, Tatsuya Ohashi, Kota Ikeda, Atsushi Takahashi, Nobuhiko Satake
    • Journal Title

      Proc. of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8(CD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The Surgery Recorder System for Minimally Invasive Surgery -Concept, Prototype and Experimental Evaluation In-Vivo2005

    • Author(s)
      Koji Ikuta, Takashi Kato, Satoshi Ando, Hiroki Ooe
    • Journal Title

      Proc. of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8(CD-ROM)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Micro to Nano Robotic Surgery2005

    • Author(s)
      Koji Ikuta
    • Journal Title

      Currently Practical Neurosurgery 15

      Pages: 1132-1136

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Medical Micro Robotics and Bio-nano machine for otorhinolaryngology2005

    • Author(s)
      Koji Ikuta
    • Journal Title

      Oto-Rhino-Laryngology 48・6

      Pages: 76-83

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] The Photograph2005

    • Author(s)
      Koji Ikuta
    • Journal Title

      O PLUS E 27・5

      Pages: 479-480

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Study on Three-dimensional Microfluidic Device using Polymer Membrane; Development of an Artificial Blood Capillary Device for Tissue Engineering2005

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Journal of JSCAS 17・4

      Pages: 587-592

    • NAID

      10021286894

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Research on Artificial Organs Using Novel Micro/Nano Device-Nanomachines fabricated and manipulated with light, and Biochemical IC chips2005

    • Author(s)
      Koji Ikuta
    • Journal Title

      Proc. 43th JSAO

      Pages: 13-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Tensegrity and Signal Transduction2005

    • Author(s)
      Keiji Naruse (Co-author)
    • Journal Title

      NTS, New Application of Liposome 752

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Real Three-dimensional Microfabrication for Biodegradable Polymers -Demonstration of microstructures with high-resolution and biocompatibility for implantable microdevices-2005

    • Author(s)
      Koji Ikuta, Akira Yamada, Fuminori Niikura
    • Journal Title

      Proc.of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8(CD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The fully integrated cell-free protein synthesis system by biochemical IC chip-set2005

    • Author(s)
      Koji Ikuta, Tatsuya Ohashi, Kota Ikeda, Atsushi Takahashi, Nobuhiko Satake
    • Journal Title

      Proc.of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8(CD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The Surgery Recorder System for Minimally Invasive Surgery -Concept, Prototype and Experimental Evaluation In-Vivo2005

    • Author(s)
      Koji Ikuta, Takashi Kato, Satoshi Ando, Hiroki Ooe
    • Journal Title

      Proc.of 6th Asian-Pacific Conference on Medical and Biological Engineering (APCMBE) 8(CD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Fabrication of Polymer Membrane Microchannel by Membrane Micro Embossing (MeME)2005

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Proc.of the International Conference on Bio-Nano-Informatics Fusion 2005 1(CD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Surgery Recorder for Minimally Invasive Surgery2005

    • Author(s)
      Koji Ikuta, Takashi Kato
    • Journal Title

      Proc.of the International Conference on Bio-Nano-Informatics Fusion 2005 1(CD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Real Three-dimensional Microfabrication for Biodegradable Polymers -Fabrication of microstructures with high-resolution and biocompatibility for implantable microdevices-2005

    • Author(s)
      A.Yamada, F.Niikura, K.Ikuta
    • Journal Title

      Proc.of the International Conference on Bio-Nano-Informatics Fusion 2005 1(CD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Development of Membrane Micro Embossing (MeME) Process for Self-Supporting Polymer Membrane Microchannel2005

    • Author(s)
      Masashi Ikeuchi, Koji Ikuta
    • Journal Title

      Proc.of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D(DVD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Development of the Surgery Recorder System2005

    • Author(s)
      Koji Ikuta, Takashi Kato
    • Journal Title

      Proc.of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D(DVD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Three-dimensional Microfabrication System for Biodegradable Microdevices with High-resolution and Bio-applicability2005

    • Author(s)
      Koji Ikuta, Akira Yamada, Fuminori Niikura
    • Journal Title

      Proc.of 2005 ASME International Mechanical Engineering Congress and Exposition I0736D(DVD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Development of Free-Surface Microstereolithography with Ultra-High Resolution to Fabricate Hybrid 3-D Microdevices2005

    • Author(s)
      Kengo Kobayashi, Koji Ikuta
    • Journal Title

      Proc.of the 2005 International Symposium on Micro-Nano Mechatronics and Human Science (MHS2005) 05TH8845

      Pages: 273-278

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Hydraulic Pressure Drive with Multi-degrees of freedom Motion for Safety Active Catheter2005

    • Author(s)
      Koji Ikuta, Hironobu Ichikawa, Daisuke Yajima
    • Journal Title

      Proc.of the 2005 International Symposium on Micro-Nano Mechatronics and Human Science (MHS2005) 05TH8845

      Pages: 279-283

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Three-dimensional Microfabrication System Toward Advanced Biodegradable Implantable Devices2005

    • Author(s)
      Akira Yamada, Fuminori Niikura, Koji Ikuta
    • Journal Title

      Proc.of 2005 IEEE Workshop on Advanced Robotics and its Social Impacts (ARSO '05) 05EX1019C(CD-ROM)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Fabrication of reconfigurable protein matrices by cracking.2005

    • Author(s)
      Zhu.X., Mills, K.L., Peters, P.R., Bahng, J.H., Liu, E.H., Shim, J., Naruse, K., Csete, M.E., Thouless, M.D., Takayama, S.
    • Journal Title

      Nature Materials 4

      Pages: 403-406

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uni-axial continuous stretch2005

    • Author(s)
      Sasamoto, A., Nagino, M., Kobayashi, S., Naruse, K., Nimura Y., Sokabe, M.
    • Journal Title

      Am J Physiol Cell Physiol. 288

      Pages: 1012-1022

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 一枚の写真2005

    • Author(s)
      生田幸士
    • Journal Title

      O PLUS E 27・5

      Pages: 479-480

    • Related Report
      2005 Annual Research Report
  • [Journal Article] マイクロからナノ手術ロボティクスへ2005

    • Author(s)
      生田幸士
    • Journal Title

      神経外科速報 15

      Pages: 1132-1136

    • NAID

      10025682229

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats

    • Author(s)
      M.Kajiya, M.Hirota, Y.Inai, T.Kiyooka, T.Morimoto, T.Iwasaki, K.Endo, S.Mohri, J.Shimizu, T.Yada, Y.Ogasawara, K.Naruse, T.Ohe, F.Kajiya
    • Journal Title

      American journal of physiology. Heart and circulatory physiology (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats

    • Author(s)
      M.Kajiya, M.Hirota, Y.Inai, T.Kiyooka, T.Morimoto, T.Iwasaki, K.Endo, S.Mohri, J.Shimizu, T.Yada, Y.Ogasawara, K.Naruse, T.Ohe, F.Kajiya
    • Journal Title

      American journal of physiology. Heart and circulatory physiology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats

    • Author(s)
      M.Kajiya, M.Hirota, Y.Inai, T.Kiyooka, T.Morimoto, T.Iwasaki, K.Endo, S.Mohri, J.Shimizu, T.Yada, Y.Ogasawara, K.Naruse, T.Ohe, F.Kajiya
    • Journal Title

      American journal of physiology. Heart and circulatory physiology (掲載決定)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Bi-phasic activation of eNOS in response to uni-axial cyclic stretch is mediated by differential mechanisms in BAECs

    • Author(s)
      Takeda, H., Komori, K., Nishikimi, N., Nimura, Y., Sokabe, M., Naruse, K.
    • Journal Title

      Life Sci. (印刷中)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Viscoelastic and dynamic nonlinear properties of airway smooth muscle tissue : roles of mechanical force and the cytoskeleton

    • Author(s)
      Ito S, Majumdar A, Kume H, Shimokata K, Naruse K, Lutchen KR, Stamenovic D, Suki B.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol (印刷中)

    • Related Report
      2005 Annual Research Report
  • [Book] レーザープロセシング応用便覧2006

    • Author(s)
      生田幸士(分担)
    • Total Pages
      590
    • Publisher
      NGTコーポレーション
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Book] 電子物性・材料の事典2006

    • Author(s)
      生田幸士(分担)
    • Total Pages
      696
    • Publisher
      朝倉書店
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Book] 岩波講座ロボット学6 ロボットフロンティア2005

    • Author(s)
      生田幸士(共著)
    • Total Pages
      218
    • Publisher
      岩波書店
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary 2005 Annual Research Report
  • [Book] テンセグリティーと情報伝達、リボソーム応用の新展開

    • Author(s)
      成瀬恵治(分担執筆)
    • Publisher
      NTS出版社(印刷中)
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Book] テンセグリティーと情報伝達、リボソーム応用の新展開

    • Author(s)
      成瀬恵治(分担執筆)
    • Publisher
      NTS出版社(印刷中)
    • Related Report
      2005 Annual Research Report
  • [Patent(Industrial Property Rights)] 受精卵の培養方法及び受精卵の培養装置2007

    • Inventor(s)
      成瀬恵治, 石田敬雄
    • Industrial Property Rights Holder
      国立大学法人岡山大学, ストレックス株式会社
    • Industrial Property Number
      2007-091036
    • Filing Date
      2007-03-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Patent(Industrial Property Rights)] 培養器2006

    • Inventor(s)
      成瀬惠治, 石田敬雄
    • Industrial Property Rights Holder
      財団法人名古屋産業科学研究所
    • Industrial Property Number
      2006-114941
    • Filing Date
      2006-04-18
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Patent(Industrial Property Rights)] 平面パッチクランプ用支持体の製造方法2006

    • Inventor(s)
      成瀬恵治
    • Industrial Property Rights Holder
      国立大学法人岡山大学
    • Industrial Property Number
      2006-133193
    • Filing Date
      2006-05-12
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Annual Research Report 2006 Final Research Report Summary
  • [Patent(Industrial Property Rights)] 培養器2006

    • Inventor(s)
      成瀬恵治, 石田敬雄
    • Industrial Property Rights Holder
      財団法人名古屋産業科学研究所
    • Industrial Property Number
      2006-114941
    • Filing Date
      2006-04-18
    • Related Report
      2006 Annual Research Report

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Published: 2005-04-01   Modified: 2016-04-21  

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