Research Project
Grant-in-Aid for Scientific Research (A)
As many as 15% of couples are unable to conceive, and males are known to be responsible for half of the instances of infertility. Although advances in medical technology have allowed some infertile couples to have children, the causes of infertility are, in most cases, unknown. Many genes are expressed exclusively in the testes, particularly in the testicular germ cells. It is reasonable to propose that functional deficiencies in the genes expressed exclusively in spermatogenesis should lead to male infertility when there is no observable abnormality in the somatic cells of various organs. Hence, in order to understand idiopathic male infertility, development of diagnosis and treatment method of male infertility based on analyses of spermatogenesis-associated genes is essential. In this study, we found infertility specific protein in human semen and identified polymorphisms associated with male infertility in human haploid germ cell specific genes.
All 2008 2007 2006 2005 Other
All Journal Article (91 results) (of which Peer Reviewed: 20 results) Presentation (20 results) Book (7 results) Remarks (2 results) Patent(Industrial Property Rights) (7 results) (of which Overseas: 1 results)
Mol. Reprod. Dev. 75
Pages: 967-975
Biochem. Biophys. Res. Commun. 369
Pages: 426-431
Fertil. & Steril. (In press)
J. Sex. Med. (In press)
Urology. (In press)
J Biol Chem. (In press)
Mol Reprod Dev 75
Biochem Biophys Res Commun 369
Biochem Biophys Res Commun (In press)
Mol Reprod Dev. (In press)
Int. J. Androl. 30
Pages: 462-475
Biol. Reprod. 76
Pages: 407-414
Pages: 211-217
J. Urol. 178
Pages: 686-691
Neuroimage 36
Pages: 830-842
Urology 70
Pages: 341-345
Br. J. Cancer 97
Pages: 952-956
Int J Androl 30
Biol Reprod 76
J. Urol 178
J. Sex. Med, Biol Reprod 76(in press)
Reprod Med Biol 6
Pages: 1-9
10018849469
Soc Reprod Fertil Suppl 65
Pages: 531-534
Int J Urol 14
Pages: 883-889
10019947540
Soc Reprod Fertil Suppl. 65
International Journal of Andrology (in press)
Biology Reproduction 76
Eur. Urol 49
Pages: 332-336
Int. J. Androl 29
Pages: 353-359
J. Endourol 20
Pages: 262-265
Asian J. Androl 8
Pages: 373-378
Int. J. Urol 13
Pages: 805-808
Reprod. Med. & Biol 5
Pages: 195-200
Urology 68
Pages: 845-851
Cancer Res 66
Pages: 11166-11671
J. Urol 176
Pages: 679-683
Pages: 1012-4
10018173616
Int J Androl 29
Pages: 323-330
Proc Natl Acad Sci U S A 103
Pages: 15148-15153
Arch Biochem Biophys 451
Pages: 23-33
J Androl 27
Pages: 326-334
Proc Natl Acad Sci USA 103
International Journal of Andrology 29
Journal of Andrology 27
Reproductive Medicine and Biology 6
内分泌・糖尿病科 23
Pages: 142-154
Int.J.Androl. (In Press)
J.Androl. (In Press)
J. Urol 173
Pages: 318-323
Pages: 2072-2075
Hum. Reprod 20
Pages: 2289-2294
Reprod. Med. & Biol 4
Pages: 213-219
J. Androl 26
Pages: 779-786
Pages: 53-57
Int. J. Imp. Res 17
Pages: 259-263
Aging Male 8
Pages: 175-179
J. Endourol 19
Pages: 808-12
Asian J. Androl 8(2)
Pages: 213-218
J. Urol 175(4)
Pages: 1446-1495
Genes Cells 10
Pages: 575-594
J Androl 26
Pages: 511-518
Developmental Cell 8
Pages: 343-352
Pages: 679-83
Int. J. Urol 13(7)
Pages: 926-31
10018173286
CPPS : Current Protein and Peptide Science 6
Pages: 567-574
CMLS : Cellular and Molecular Life Sciences 62
Pages: 344-354
Dev.Cell 8
Nucleic Acids Res. 33
Pages: 3401-3411
J.Androl. 26
Mol.Cell.Biol. 25
Pages: 7107-7119
Pages: 753-762
Curr.Protein Pept.Sci. 6
Reprod.Med.Biol. 4
Fertil & Steril (in press)
Urology (in press)
J Biol Chem (in press)
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