Analyses of calcium-activated potassium channels as novel targets for new drug therapy

• Project/Area Number: 17390045
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Medical pharmacy
• Research Institution: Nagoya City University
• Principal Investigator: IMAIZUMI Yuji Nagoya City University, Graduate School of Pharmaceutical Sciences, Professor (60117794)
• Co-Investigator(Kenkyū-buntansha): OHYA Susumu Nagoya City University, Graduate School of Pharmaceutical Sciences, Associate Professor (70275147) ; YAMAMURA Hisao Nagoya City University, Graduate School of Pharmaceutical Sciences, Research Associate (80398362) ; TOGARI Akihumi Aichi Gakuin University, School of Dentistry, Professor (80126325)
• Project Period (FY): 2005 – 2007
• Project Status: Completed (Fiscal Year 2007)
• Budget Amount: ¥16,100,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥1,200,000); Fiscal Year 2007: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2006: ¥4,000,000 (Direct Cost: ¥4,000,000); Fiscal Year 2005: ¥6,900,000 (Direct Cost: ¥6,900,000)
• Keywords: calcium-activated potassium channel / BK channel / SK channel / potassium channel opener / ryanodine receptor / caveolae / drug development / potential sensitive fluorescent / カルシウム活性化カリウムチャネル / TASKチャネル / ピマル酸 / 心筋ミトコンドリア / 心筋保護作用 / 間質細胞 / ペースメーカー細胞

Research Abstract

In excitable cells, such as CNS neurons, negative feedback regulation systems for intracellular Ca^<2+> homeostasis work to prevent Ca^<2+> overlord, when excess excitability and resulting excess Ca^<2+> influx occurs. Activation of Ca^<2+> activated K+ (Kca) channels is know to be one ` of the most important components responsible for the negative feedback regulation of [Ca2^+]_i in excitable cells. This project was undertaken to elucidate the molecular mechanism for the regulation of Kca channel activity and to search changes in the regulation diseases. The goal of this project is to find out molecular seeds targeting on K_ca channels in some diseases. The following development was obtained during the research period. (1) It was found that small conductance K_ca (SK) channel in vascular endothelial cell lines originally derived from bovine blood-brain barrier has significant functional role in endothelial; proliferation stimulated by ATP presumably released from astrocytes in CNS. (J BC,2006; J Pharmacol Sci, 104, 2007). (2) The deep impact of ryanodine receptor type2 (RyR2) to the mechanism for negative feedback regulation of [Ca^<2+>], via spontaneous Ca^<2+> release(Ca^<2+> spark) from sarcoplasmic reticulum and subsequent activation of large conductance Kca (BK) channel was found using urinary bladder smooth muscle cells from wild type and RyR2 heterozygous KO mice. A line of evidence indicates that RyR2 contributes to the bladder continent as 'a key molecule regulating resting membrane potential and muscular tonus as well as excitation-contraction coupling (J Physiol, 2007, J Pharmacol Sci, 103, 2007). (3) It was found that potential sensitive oxonol dyes act as potent BK channel openers. It is the first synthesized compound which shows opening property selective to BK81 and 84 subunits over BK62. The oxonol compounds may be a seed of 8 subunit selective BK channel opener (Mol Pharmacol, 2007). (4) It has been known that the contractile responses of isolated large arteries from spontaneously hypertensive rats (SHR) to agonists are markedly potentiated in low pH bathing solution. It was found that the enhanced expression of BK channels in arterial smooth muscles of SHR and its sensitivity to extracellular pH are responsible for the acid pH induced potentiation of contraction (Am J Physiol, 2007).

Research Products

• [Journal Article] Ca^<2+>シグナルから膜電位変化ヘシグナル変換する分子集積体としてのトランスポートソームの機能解析 (2008)
  • Author(s): 今泉 祐治
  • Journal Title: TRANSPORTSOME 2007冬号 Pages: 11-14
• [Journal Article] Cell-Cycle-Dependent Regulation of Ca^<2+>-activated K^+ Channel in Jurkat T-lymphocyte (2007)
  • Author(s): Takashi Morimoto
  • Journal Title: J. Pharmacol. Sci 104 Pages: 94-98
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Characteristics of the ATP-lnduced Ca^<2+>-entry pathway in the t-BBEC 117 Cell Line Derived From Bovine Brain Endothelial Cells (2007)
  • Author(s): Daijyu Yamazaki
  • Journal Title: J. Pharmacol. Sci 104 Pages: 103-107
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle (2007)
  • Author(s): Shingo Hotta
  • Journal Title: J. Physiol.(Cond.) 582 Pages: 489-506
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Voltage-Sensitive Oxonol Dyes Are Novel Large-Conductance Ca^<2+>-Activated K^+ channel Activators Selective forβ1 andβ4 but Not for β2 Subunits (2007)
  • Author(s): Takashi Morimoto
  • Journal Title: Mol. Pharmacol 71 Pages: 1075-1088
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] C-type natriuretic peptide activates a nonselective cation current in acutely isolated ratcardiac fibroblasts via natriuretic peptide Creceptor mediated signaling (2007)
  • Author(s): Robert A. Rose
  • Journal Title: J. Physiol.(Cond.) 580 Pages: 255-274
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Methyl-β-cyclodextrin Prevents Ca^<2+>-induced Ca^<2+> Release in Smooth Muscle Cells of Mouse Urinary Bladder (2007)
  • Author(s): Shingo Hotta
  • Journal Title: J. Pharmacol. Sci 103 Pages: 121-126
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Cell-Cycle-Dependent Regulation of Ca^<2+>-activated K^+ Channel in Jurkat T-Iymphocyte (2007)
  • Author(s): Takashi, Morimoto, Susumu, Ohya, Hidetoshi, Hayashi, Kikuo, Onozaki, Yuji, Imaizumi
  • Journal Title: J. Pharmacol. Sci 104 Pages: 94-98
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Characteristics of the ATP-Induced Ca^<2+>-entry pathway in the t-BBEC 117 Cell Line Derived From Bovine Brain Endothelial Cells (2007)
  • Author(s): Daiju, Yamazaki, Susumu, Ohya, Kiyofumi, Asai, Yuji, Imaizumi
  • Journal Title: J. Pharmacol. Sci 104 Pages: 103-107
  • NAID: 10024314163
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Ryanodine receptor type 2 deficiency changes excitation- contraction coupling and membrane potential in urinary bladder smooth muscle (2007)
  • Author(s): Shingo, Hotta, Kozo, Morimura, Susumu, Ohya, Katsuhiko, Muraki, Hiroshi, Takesmma, Yuji, Imaizum
  • Journal Title: J. Physiol. (Lond.) 582 Pages: 489-506
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Voltage-Sensitive Oxonol Dyes Are Novel Large-Conductance Ca^<2+> -Activated K^+ channel Activators Selective for 131 and 34 but Not for β 2 Subunits (2007)
  • Author(s): Takashi, Morimoto, Kazuho, Sakamoto, Hiroko, Sade, Susumu, Ohya, KatsunlKo, Muraki, Yuji, Imaizumi
  • Journal Title: Mol.Pharmacol 71 Pages: 1075-1088
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] C-type natriuretic peptide activates a nonselective cation current in acutely isolated rat cardiac fibroblasts via natriuretic peptide C receptor mediated signaling (2007)
  • Author(s): Robert, A. Rose, Noriyuki, Hatano, Susumu, Ohya, Yuji, Imaizumi, Wayne, R. Giles
  • Journal Title: J. Physiol. (Lond.) 580 Pages: 255-274
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Methyl-β-cyclodextrin Prevents Ca^<2+>-induced Caz+ Release in Smooth Muscle Cells of Mouse Urinary Bladder (2007)
  • Author(s): Shingo, Hotta, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Journal Title: J. Pharmacol. Sci 103 Pages: 121-126
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Cell-cycle-dependent regulation of Ca^<2+>-activated K^+ channel in Jurkat T-lymphocyte (2007)
  • Author(s): Morimoto T
  • Journal Title: J. Pharmacol. Sci. 104 Pages: 94-98
  • Peer Reviewed
• [Journal Article] Characteristics of the ATP-Induced Ca^<2+>-entry pathway in the t-BBEC 117 cell line derived from bovine brain endothelial cells (2007)
  • Author(s): Yamazaki D
  • Journal Title: J. Pharmacol. Sci. 104 Pages: 103-107
  • Peer Reviewed
• [Journal Article] Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle (2007)
  • Author(s): Hotta S
  • Journal Title: J. Physiol.(Lond.) 582 Pages: 489-506
  • Peer Reviewed
• [Journal Article] Voltage-sensitive oxonol dyes are novel BK channel activators selective for β1 and β4 but not for β2 subunits (2007)
  • Author(s): Morimoto T
  • Journal Title: Mol. Pharmacol. 71 Pages: 1075-1088
  • Peer Reviewed
• [Journal Article] CNP activates a nonselective cation current in acutely isolated rat cardiac fibroblasts via NPR-C receptor mediated signaling (2007)
  • Author(s): Robert A. Rose
  • Journal Title: J. Physiol.(Lond.) 580 Pages: 255-274
  • Peer Reviewed
• [Journal Article] Methyl-β-cyclodextrin prevents Ca^<2+>-induced Ca^<2+> release in smooth muscle cells of mouse urinary bladder (2007)
  • Author(s): Hotta S
  • Journal Title: J. Pharmacol. Sci. 103 Pages: 121-126
  • Peer Reviewed
• [Journal Article] Methyl-β-cyclodextrin prevents Ca^<2+>-induced Ca^<2+> release in smooth muscle cells of mouse urinary bladder (2007)
  • Author(s): Hotta S, Yamamura H, Ohya S, Imaizumi Y
  • Journal Title: J Pharmacol Sci 103(1) Pages: 121-126
  • NAID: 10024312258
• [Journal Article] Voltage-sensitive oxonol dyes are novel large-conductance Ca^<2+>-activated K^+ channel activators selective for β1 and β4 but not for β2 subunits (2007)
  • Author(s): Morimoto T, Sakamoto K, Sade H, Ohya S, Muraki K, Imaizumi Y
  • Journal Title: Mol Pharmacol 71(4) Pages: 1075-1088
• [Journal Article] Novel functions of small conductance Cat^<2+>-activated K^+ channel in enhanced cell proliferation by ATP in Brain Endothelial Cells (2006)
  • Author(s): Daiju Yamazaki
  • Journal Title: J. Biol. Chem 281 Pages: 38430-38439
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Molecular and electrophysiological characteristics of K^+ conductance sensitive to acidic pH in aortic smooth muscle cells of WKY and SHR (2006)
  • Author(s): Hidekazu Kiyoshi
  • Journal Title: Am. J. Physiol. Heart Circ. Physiol 291
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Voltage-dependent Ca^<2+>-Channel Block by Openers of Intermediate and Small Conductance Ca<2+>-activated K^+ channels in Urinary Bladder Smooth Muscle Cells (2006)
  • Author(s): Kozo Morimura
  • Journal Title: J. Pharmacol. Sci 100 Pages: 237-241
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Inherent pacemaker function of duodenal GIST (2006)
  • Author(s): Shinji Furuzono
  • Journal Title: Eur. J. Cancer 42 Pages: 243-248
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Molecular Mechanisms for Large Conductance Ca^<2+>-Activated K^+ Channel Activation by a Novel Opener, 12, 14-Dichlorodehydroabietic Acid (2006)
  • Author(s): Kazuho Sakamoto
  • Journal Title: J. Pharmacol. Exp. Ther 316 Pages: 144-153
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Two-step Ca^<2+> intracellular release underlies excitation-contraction coupling in mouse urinary bladder myocytes (2006)
  • Author(s): Kozo Morimura
  • Journal Title: Am. J. Physiol. Cell Physiol 290
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Activation of large-conductance, Ca^<2+>-activated K^+ channels by cannabinoids (2006)
  • Author(s): Hiroko Sade
  • Journal Title: Am. J. Physiol. Cell Physiol 290
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] 血管に対するチャネル開口薬の作用 (2006)
  • Author(s): 今泉 祐治
  • Journal Title: 心電図 26 Pages: 11-19
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] A new insight into the function of TRPV2 (2006)
  • Author(s): Muraki K
  • Journal Title: circulatory organs TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades(Frontiers in Neuroscience)(Wolfgang B. Liedtke, ed.), Chapter 28, CRC Press Pages: 389-396
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Novel functions of small conductance Ca^<2+>-activated K+ channel in enhanced cell proliferation by ATP in Brain Endothelial Cells J. Biol. Chem (2006)
  • Author(s): Daiju, Yamazaki, Mineyoshi, Aoyama, Susumu, Ohya, Katsuhiko, Muraki, Kiyofumi, Asai, Yuji, Imaizumi
  • Journal Title: J. Biol. Chem 281 Pages: 38430-38439
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Molecular and electrophysiological characteristics of K^+ conductance sensitive to acidic pH in aortic smooth muscle cells of WKY and SHR (2006)
  • Author(s): Hidekazu, Kiyoshi, Daiju, Yamazaki, Susumu, Ohya, Mika, Kitsukawa, Katsuhiko, Muraki, Shinya, Saito, Yasushi, Ohizumi, Yuji, Imaizumi
  • Journal Title: Am. J. Physiol. Heart Circ. Physiol 291
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Voltage-dependent Ca^<2+>-Channel Block by Openers of Intermediate and Small Conductance Ca^<2+>-activated K+ channels in Urinary Bladder Smooth Muscle Cells (2006)
  • Author(s): Kozo, Morimura, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Journal Title: J. Pharmacol. Sci 100 Pages: 237-241
  • NAID: 10018240450
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Inherent pacemaker function of duodenal GIST (2006)
  • Author(s): Shinji, Furuzono, Susumu, Ohya, Soichiro, Inoue, Akimasa, Nakao, Yuji, Imaizumi, Shinsuke, Nakayama
  • Journal Title: Eur. J. Cancer 42 Pages: 243-248
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Molecular, Mechanisms, for Large, Conductance Ca^<2+>-Activated K+ Channel Activation by a Novel Opener, 12,14-Dichlorodehydroabietic Acid (2006)
  • Author(s): Kazuho, Sakamoto, Taro, Nonomura, Susumu, Ohya, Katsuhiko, Muraki, Tomohiko, Ohwada, Yuji, Imaizumi
  • Journal Title: J. Pharmacol. Exp. Ther 316 Pages: 144-153
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Two-step Ca^<2+> intracellular release underlies excitation-contraction coupling in mouse urinary bladder myocytes (2006)
  • Author(s): Kozo, Morimura, Yoshiaki, Ohi, Hisao, Yamamura, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Journal Title: Am. J. Physiol. Cell Physiol 290
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Activation of large-conductance, Ca^<2+>-activated K^+ channels by cannabinoids Am (2006)
  • Author(s): Hiroko, Sade, Katsuhiko, Muraki, Susumu, Ohya, Noriyuki, Hatano, Yuji, Imaizumi
  • Journal Title: J. Physiol. Cell Physiol 290
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Effects of K^+ channel openers on vasculature Jap (2006)
  • Author(s): Yuji, Imaizumi, Katsuhiko, Muraki
  • Journal Title: J. of Electrocardiol 26 Pages: 11-19
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Novel functions of small conductance Ca^<2+>-activated K^+ channel in enhanced cell proliferation by ATP in brain endothelial cells (2006)
  • Author(s): Yamazaki D, Aoyama M, Ohya S, Muraki K, Asai K, Imaizumi Y
  • Journal Title: J Biol Chem 281(50) Pages: 38430-38439
• [Journal Article] Molecular and electrophysiological characteristics of K^+ conductance sensitive to acidic pH in aortic smooth muscle cells of WKY and SHR (2006)
  • Author(s): Kiyoshi H, Yamazaki D, Ohya S, Kitsukawa M, Muraki K, Saito SY, Ohizumi Y, Imaizumi Y
  • Journal Title: Am J Physiol Heart Circ Physiol 291(6)
• [Journal Article] 血管に対するチャネル開口薬の作用 (2006)
  • Author(s): 今泉祐治, 村木克彦
  • Journal Title: 心電図 26 Pages: 11-19
• [Journal Article] Two-step Ca^<2+> intracellular release underlies excitation-contraction coupling in mouse urinary bladder myocytes (2006)
  • Author(s): Morimura et al.
  • Journal Title: American Journal of Physiology 290(2)
• [Journal Article] Molecular mechanisms for BK channel activation by a novel opener, 12, 14-dichlorodehydroabietic acid (2006)
  • Author(s): Sakamoto et al.
  • Journal Title: Journal of Pharmacology and Experimental Therapeutics 316(1) Pages: 144-153
• [Journal Article] Activation of large-conductance Ca^<2+> activated K^+ channels by cannabinoids (2006)
  • Author(s): Sade et al.
  • Journal Title: American Journal of Physiology 290(1)
• [Journal Article] Inherent pacemaker function of duodenal GIST (2006)
  • Author(s): Furuzono et al.
  • Journal Title: European Journal of Cancer 42(2) Pages: 243-248
• [Journal Article] Sulphonylurea receptors differently modulate ICC pacemaker Ca^<2+> activity and smooth muscle contractility (2005)
  • Author(s): Shinsuke Nakayama
  • Journal Title: J.Cell Sci 118 Pages: 4167-4173
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Cardioprotective effects of estradiol include the activation of large-conductance Ca^<2+>-activated K^+ channels in cardiac mitochondria (2005)
  • Author(s): Susumu Ohya
  • Journal Title: Am. J. Physiol. Heart Circ. Physiol 289
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] K^+ Currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts (2005)
  • Author(s): Lisa Chilton
  • Journal Title: Am. J. Physiol. Heart Circ. Physiol 288
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Ca^<2+> Releasing Channels (2005)
  • Author(s): Yuji Imaizumi
  • Journal Title: Pulmonary Vascular Smooth Muscle Cells Ion Channels in the Pulmonary Vasculature, Chapter7, CRC Press Pages: 147-165
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Cardioprotective effects of estradiol include the activation of large-conductance Ca^<2+>-activated K^+ channels in cardiac mitochondria (2005)
  • Author(s): Susumu, Ohya, Yukiko, Kuwata, Kazuho, Sakamoto, Katsuhiko, Muraki, Yuji, Imaizumi
  • Journal Title: Am. J. Physiol. Heart Circ. Physiol 289
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Sulphonylurea receptors differently modulate ICC pacemaker Ca^<2+> activity and smooth muscle contractility (2005)
  • Author(s): Shinsuke, Nakayama, Susumu, Ohya, Hong-Nian, Liu, Toshiya, Watanabe, Shinji, Furuzono, Jing, Wang, Yuji, Nishizawa, Masahiro, Aoyama, Naruhiko, Murase, Tatsuaki, Matsubara, Yasushi, Ito, Yuji, Imaizumi, Shunichi, Kajioka
  • Journal Title: J. Cell Sci 118 Pages: 4163-4173
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] K^+ Currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts (2005)
  • Author(s): Lisa, Chilton, Susumu, Ohya, Darren, H., Freed, Eric, George, Vanja, Drobic, Yoshiyuki, Shibukawa, K., Andrew Mac, Cannell, Yuji, Imaizumi, Robert, B. Clark, Ian, M. C., Dixon, Wayne, R. Giles
  • Journal Title: Am. J. Physiol. Heart Circ. Physiol 288
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Cardioprotective effects of estradiol include the activation of large-conductance Ca^<2+>-activated K^+ channels in cardiac mitochondria (2005)
  • Author(s): Ohya et al.
  • Journal Title: American Journal of Physiology 289(4)
• [Journal Article] Sulphonylurea receptors differently modulate ICC pacemaker Ca^<2+> activity and smooth muscle contractility (2005)
  • Author(s): Nakayama et al.
  • Journal Title: Journal of Cell Science 118(18) Pages: 4163-4173
• [Journal Article] K^+ currents regulate the resting membrane potential, proliferation, and contractile responses in ventricular fibroblasts and myofibroblasts (2005)
  • Author(s): Chilton et al.
  • Journal Title: American Journal of Physiology 288(6)
• [Journal Article] Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle
  • Author(s): Hotta S, Kozo M, Ohya S, Muraki K, Takeshima H, Imaizumi Y
  • Journal Title: J Physiol (in press)
• [Journal Article] CNP activates a nonselective cation current in acutely isolated rat cardiac fibroblasts via NPR-C receptor mediated signaling
  • Author(s): Rose RA, Hatano N, Ohya S, Imaizumi Y, Giles WR
  • Journal Title: J Physiol (in press)
• [Presentation] 脳血管内皮細胞において内向き整流性K^+チャネル(Kir2.1)の活性化により生じる過剰な過分極は細胞死を引き起こす (2009)
  • Author(s): 山崎 大樹
  • Organizer: 生体機能と創薬シンポジウム
  • Place of Presentation: 福岡
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Functional roles of voltage-gated K^+ channels in RINm5F cells (2008)
  • Author(s): Takuya, Kimura, Susumu, Ohya, Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: The 128th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-28
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] RINm5F細胞における電位依存性K^+チャネルの機能的役割 (2008)
  • Author(s): 木村拓哉
  • Organizer: 日本薬学会第128年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-28
• [Presentation] BKチャネルのDiBAC_4(3)によるβサブユニット選択的活性化分子機構の解明 (2008)
  • Author(s): 藤高 啓右
  • Organizer: 日本薬学会第128年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-27
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 末梢組織ペースメーカーモデルにおける細胞間電気シグナル伝播機構の解明 (2008)
  • Author(s): 橋爪 圭吾
  • Organizer: 日本薬学会第128年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-27
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] RINm5F細胞における電位依存陸K^+チャネルの機能的役割 (2008)
  • Author(s): 木村 拓哉
  • Organizer: 日本薬学会第128年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-27
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] The subunit selective activation mechanism of BK channel by DiBAC4(3) (2008)
  • Author(s): Keisuke, Fujitaka, Takashi, Morimoto, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 128th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-27
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Intercellular electrical coupling in ICC-like pacemaker cells (2008)
  • Author(s): Keigo, Hashidume, Taisuke, Kimura, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 128th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-27
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 平滑筋におけるカルモジュリン様タンパク質及びCa^<2+>/カルモジュリン依存性キナーゼHによる早期不活性化K^+チャネル制御 (2008)
  • Author(s): 大矢 進
  • Organizer: 第85回日本生理学会大会
  • Place of Presentation: 東京
  • Year and Date: 2008-03-26
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Molecular basis for the regulation of rapidly-inactivating, A-type K^+ channels by CaM-like proteins and CaMKII in smooth muscles (2008)
  • Author(s): Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 85^th Annual Meeting of the Physiological Society of Japan
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2008-03-26
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 平滑筋におけるカルモジュリン様タンパク質及びCa^<2+>/カルモジュリン依存性キナーゼIIによる早期不活性化K^+チャネル制御 (2008)
  • Author(s): 大矢進
  • Organizer: 第85回日本生理学会大会
  • Place of Presentation: 東京
  • Year and Date: 2008-03-26
• [Presentation] 血管平滑筋細胞におけるBKチャネルの一分子動態解析 (2008)
  • Author(s): 山村 寿男
  • Organizer: 第85回日本生理学会大会
  • Place of Presentation: 東京
  • Year and Date: 2008-03-25
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] テストステロンによる扁桃体の大コンダクタンスCa^<2+>活性化K^+チャネル発現調節 (2008)
  • Author(s): 大野 晃稔
  • Organizer: 第85回日本生理学会大会
  • Place of Presentation: 東京
  • Year and Date: 2008-03-25
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Single-molecule imaging of BK channels in vascular smooth muscle cells (2008)
  • Author(s): Hisao, Yamamura, Chikako, Ikeda, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 85th Annual Meeting of the Physiological Society of Japan
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2008-03-25
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Regulation of Large conductance Ca^<2+> activated K^+ channels expression in rat amygdala by testosterone (2008)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: The 85th Annual Meeting of the Physiological Society of Japan
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2008-03-25
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Na^+/Ca^<2+>交換輸送体(NCX)高発現膀胱における自発収縮充進の機構解析 (2008)
  • Author(s): 村田 秀道
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-19
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Molecular imaging analyses of functional interaction between ion channels and regulatory proteins in subplasmalemmalmicrodomains (2008)
  • Author(s): Yuji, Imaizumi, Chikako, Ikeda, Hisao, Yamamura
  • Organizer: The 81st Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-19
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Functional analysis of Na^+/Ca^<2+> exchanger (NCX) for spontaneous contractions in urinary bladder smooth muscle (2008)
  • Author(s): Hidemichi, Murata, Hisao, Yamamura, Susumu, Ohya, Takahiro, Iwamoto, Yuji, Imaizumi
  • Organizer: The 81st Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-19
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Na^+/Ca^<2+>交換輸送体(NCX)高発現膀胱における自発収縮亢進の機構解析 (2008)
  • Author(s): 村田秀道
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-19
• [Presentation] 平滑筋細胞における局所Ca^<2+>変動のTIRF画像解析 (2008)
  • Author(s): 山村 寿男
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 松果体細胞における大コンダクタンスCa^<2+>活性化K^+チャネルの生理的意義の解明 (2008)
  • Author(s): 水谷 浩也
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] BKチャネル分子のTIRF画像解析 (2008)
  • Author(s): 池田 知佳子
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] CD3およびCD28刺激によるJurkat T細胞におけるkv1.3電流の調節 (2008)
  • Author(s): 松下 雄一朗
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 微小膜ドメインにおけるイオンチャネル協関制御分子機構の可視化 (2008)
  • Author(s): 今泉 祐治
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] TIRF imaging of local Ca^<2+> transients in smooth muscle cells (2008)
  • Author(s): Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: The 81st Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Physiological roles of large-conductance Ca^<2+>-activated K+ channel in rat pinealocytes (2008)
  • Author(s): Hiroya, Mizutani, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 81st Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] TIRF imaging of BK channel molecules (2008)
  • Author(s): Chikako, Ikeda, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 81st Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Modulation by CD3/CD28 activation on Kv1.3 K^+ current in human leukemia Jurkat cells (2008)
  • Author(s): Yuichiro, Matsushita, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 81st Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-18
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Dahl食塩感受性高血圧ラット腎動脈平滑筋におけるK^+チャネル機能変化 (2008)
  • Author(s): 荻原 和信
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-17
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト由来軟骨肉腫細胞(OUMS-27)に対するニフルミ酸の作用 (2008)
  • Author(s): 船橋 賢司
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2008-03-17
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Modulated functions of K^+ channels in renal artery smooth muscles of Dahl salt-sensitive rat (2008)
  • Author(s): Kazunobu, Ogiwara, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 81st Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-17
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Effects of niflumic acid on ion channels in human chondrosarcoma cell line (OUMS-27) (2008)
  • Author(s): Kenji, Funahashi, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 81st Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2008-03-17
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Dah1食塩感受性高血圧ラット腎動脈平滑筋におけるK^+チャネル機能変化 (2008)
  • Author(s): 荻原和信
  • Organizer: 第81回日本薬理学会年会
  • Place of Presentation: 大阪
  • Year and Date: 2008-03-17
• [Presentation] Visualization of local Ca^<2+> transients in smooth muscle cells using total internal refection fluorescence microscope (2008)
  • Author(s): Hisao Yamamura
  • Organizer: Pan-Pacific International Partnership Conference on Pharmaceutical and Life Sciences(The 4th US-Japan Joint Conference)
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2008-02-22
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Visualization of local Ca^<2+> transients in smooth muscle cells using total internal reflection fluorescence microscope (2008)
  • Author(s): Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: Pan-Pacific International Partnership Conference on Pharmaceutical and Life Sciences (The 4th US-Japan Joint Conference)
  • Place of Presentation: Nagoya
  • Year and Date: 2008-02-22
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] TIRF imaging of Ca^<2+>-induced Ca^<2+> release in smooth muscle cells (2008)
  • Author(s): Hisao Yamamura
  • Organizer: Biophysical Society-52th Annual Meeting
  • Place of Presentation: Long Beach, USA
  • Year and Date: 2008-02-03
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] TIRF imaging of Ca^<2+>-induced Ca^<2+> release in smooth muscle cells (2008)
  • Author(s): Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: Biophysical Society -52th Annual Meeting-
  • Place of Presentation: Long Beach, USA
  • Year and Date: 2008-02-03
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 食塩感受性高血圧モデルラット腎動脈平滑筋におけるK^+チャネル機能変化 (2007)
  • Author(s): 荻原 和信
  • Organizer: 第112回日本薬理学会近畿部会
  • Place of Presentation: 大阪
  • Year and Date: 2007-11-30
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 大動脈平滑筋細胞におけるBKチャネルの一分子動態可視化解析 (2007)
  • Author(s): 山村 寿男
  • Organizer: 第17回日本循環薬理学会
  • Place of Presentation: 大阪
  • Year and Date: 2007-11-30
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Single-molecule imaging of BK channels in aortic smooth muscle cells (2007)
  • Author(s): Hisao, Yamamura, Chikako, Ikeda, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 17th Annual Meeting of Japanese Associations of Cardiovascular Pharmacology
  • Place of Presentation: Osaka
  • Year and Date: 2007-11-30
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Modulated functions of K+ channels in renal artery smooth muscles of Dahl salt-sensitive rat (2007)
  • Author(s): Kazunobu, Ogiwara, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 112th Kinki Branch Meeting of The Japanese Pharmacological Society in Osaka
  • Place of Presentation: Osaka
  • Year and Date: 2007-11-16
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Molecular mechanisms underlying β subunit selective activation of BK channel by DiBAC_4(3) (2007)
  • Author(s): Yuji Imaizumi
  • Organizer: 5th Annual Discovery on Target
  • Place of Presentation: Boston, USA
  • Year and Date: 2007-10-16
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Molecular mechanisms underlying βsubunit selective activation of BK channel by DiBAC4(3) (2007)
  • Author(s): Yuji, Imaizumi, Takashi, Morimoto, Keisuke, Fujitaka, Susumu, Ohya
  • Organizer: 5th Annual Discovery on Target
  • Place of Presentation: Boston, USA
  • Year and Date: 2007-10-16
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Molecular mechanisms underlying β subunit selective activation of BK channel by DiBAC_4(3) (2007)
  • Author(s): Yuji Imaizumi
  • Organizer: 5th Annual Discovery on Target.
  • Place of Presentation: Boston, MA, USA
  • Year and Date: 2007-10-16
• [Presentation] ヒト前立腺癌におけるCa^<2+>活陸化K^+チャネル遺伝子発現 (2007)
  • Author(s): 丹羽 里実
  • Organizer: 第17回日本医療薬学会
  • Place of Presentation: 群馬
  • Year and Date: 2007-09-30
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Gene expression of Ca^<2+>-activated K^+ channels in human prostate cancer (2007)
  • Author(s): Satomi, Niwa, Susumu, Ohya, Akitoshi, Ohno, Yoshiyuki, Kojima, Syoichi, Sasaki, Kenjiro, Kori, Yuji, Imaizumi
  • Organizer: The 17th Annual Metting of Japanese Society of Pharmaceutical Health Care and Sciences
  • Place of Presentation: Gunma
  • Year and Date: 2007-09-30
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] ヒト前立腺癌におけるCa^<2+>活性化K^+チャネル遺伝子発現 (2007)
  • Author(s): 丹羽里実
  • Organizer: 第17回 日本医療薬学会
  • Place of Presentation: 群馬
  • Year and Date: 2007-09-30
• [Presentation] 全反射蛍光顕微鏡を用いたBKチャネルの一分子可視化解析 (2007)
  • Author(s): 池田 知佳子
  • Organizer: 生体機能と創薬シンポジウム2007
  • Place of Presentation: 金沢
  • Year and Date: 2007-09-13
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 平滑筋Ca^<2+>誘発性Ca^<2+>遊離のTIRF画像解析 (2007)
  • Author(s): 山村 寿男
  • Organizer: 生体機能と創薬シンポジウム2007
  • Place of Presentation: 金沢
  • Year and Date: 2007-09-13
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Single molecule imaging of BK channels using total internal reflection fluorescence microscopy (2007)
  • Author(s): Chikako, Ikeda, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: Biofunction and Drug Discovery Symposium 2007
  • Place of Presentation: Kanazawa
  • Year and Date: 2007-09-13
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] TIRF imaging of Ca^<2+>-induced Ca^<2+> release in smooth muscle cells (2007)
  • Author(s): Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: Biofunction and Drug Discovery Symposium 2007
  • Place of Presentation: Kanazawa
  • Year and Date: 2007-09-13
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 平滑筋興奮の多様性と興奮収縮連関 (2007)
  • Author(s): 今泉 祐治
  • Organizer: 第49回日本平滑筋学会総会
  • Place of Presentation: 奈良
  • Year and Date: 2007-07-06
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Diversity of membrane excitability in smooth muscles and excitation-contraction coupling [Educational Lecture] (2007)
  • Author(s): Yuji, Imaizumi
  • Organizer: The 49th Annual Meeting of Japan Society of Smooth Muscle Research
  • Place of Presentation: Nara
  • Year and Date: 2007-07-06
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 血管平滑筋細胞の静止時Ca^<2+>動態制御機構におけるNa^+/Ca^<2+>交換輸送体の役割 (2007)
  • Author(s): 村田 秀道
  • Organizer: 第49回日本平滑筋学会総会
  • Place of Presentation: 奈良
  • Year and Date: 2007-07-05
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 生殖器平滑筋のテストステロンによる大コンダクタンスCa^<2+>活性化K^+チャネルとリアノジン受容体の発現変化 (2007)
  • Author(s): 大野 晃稔
  • Organizer: 第49回日本平滑筋学会総会
  • Place of Presentation: 奈良
  • Year and Date: 2007-07-05
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Roles of Na^+/Ca^<2+> exchanger on resting Ca^<2+> mobilization in vascular smooth muscle cells (2007)
  • Author(s): Hidemichi, Murata, Hisao, Yamamura, Susumu, Ohya, Takahiro, Iwamoto, Yuji, Imaizumi
  • Organizer: The 49th Annual Meeting of Japan Society of Smooth Muscle Research
  • Place of Presentation: Nara
  • Year and Date: 2007-07-05
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Changes in expression of large-conductance Ca^<2+>-activated K+ channel and ryanodine receptor by testosterone (2007)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: The 49th Annual Meeting of Japan Society of Smooth Muscle Research
  • Place of Presentation: Nara
  • Year and Date: 2007-07-05
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 松果体細胞におけるニコチン誘発性の細胞内Ca^<2+>シグナルとCa^<2+>感受性チャネルの機能解析 (2007)
  • Author(s): 水谷 浩也
  • Organizer: 第111回日本薬理学会近畿部会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-06-15
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト由来軟骨肉腫細胞株(OUMS-27)におけるイオンチャネルの機能解析 (2007)
  • Author(s): 舩橋 賢司
  • Organizer: 第111回日本薬理学会近畿部会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-06-15
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Functional roles of ion channels involved in nicotinic ACh receptor-mediated Ca^<2+> signal in rat pinealocytes (2007)
  • Author(s): Hiroya, Mizutani, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 111th Kinki Branch Meeting of The Japanese Pharmacological Society in Nagoya
  • Place of Presentation: Nagoya
  • Year and Date: 2007-06-15
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Functional characterization of ion channels expressed in human chondrosarcoma cell line, OUMS-27 (2007)
  • Author(s): Kenji, Funahashi, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 111th Kinki Branch Meeting of The Japanese Pharmacological Society in Nagoya
  • Place of Presentation: Nagoya
  • Year and Date: 2007-06-15
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 短期培養cardiac fibroblastにおけるATP誘発クロライド電流 (2007)
  • Author(s): 波多野紀行
  • Organizer: 第111回日本薬理学会近畿部会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-06-15
• [Presentation] ウサギ洞房結節細胞におけるSIP受容体作動薬ONO-WE-061の作用 (2007)
  • Author(s): 岩浪 真
  • Organizer: 日本薬学会第127年会
  • Place of Presentation: 富山
  • Year and Date: 2007-03-30
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 抗アンドロゲン薬によるラット精管平滑筋のリアノジン受容体機能・発現変化 (2007)
  • Author(s): 大野 晃稔
  • Organizer: 日本薬学会第127年会
  • Place of Presentation: 富山
  • Year and Date: 2007-03-30
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Effects of ONO-WE-061, a novel agonist for S1P receptor, in rabbit sinus node cells (2007)
  • Author(s): Makoto, Iwaanmi, Katsuhiko, Muraki, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 127th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Toyama
  • Year and Date: 2007-03-30
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Changes in function and expression of ryanodine receptor in rat vas deferens smooth muscles by anti-androgen drug (2007)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: The 127th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Toyama
  • Year and Date: 2007-03-30
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] ヒト前立腺癌におけるイオンチャネル遺伝子発現プロファイル (2007)
  • Author(s): 丹羽 里実
  • Organizer: 日本薬学会第127年会
  • Place of Presentation: 富山
  • Year and Date: 2007-03-28
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 平滑筋細胞におけるCa^<2+>誘発性Ca^<2+>遊離機構のTIRF画像解析 (2007)
  • Author(s): 山村 寿男
  • Organizer: 日本薬学会第127年会
  • Place of Presentation: 富山
  • Year and Date: 2007-03-28
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Gene profiles of ion channels in human prostate cancer (2007)
  • Author(s): Satomi, Niwa, Susumu, Ohya, Akitoshi, Ohno, Yoshiyuki, Kojima, Syoichi, Sasaki, Kenjiro, Kori, Yuji, Imaizumi
  • Organizer: The 127th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Toyama
  • Year and Date: 2007-03-28
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] TIRF imaging of Ca^<2+>-induced Ca^<2+> release in smooth muscle cells (2007)
  • Author(s): Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: The 127th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Toyama
  • Year and Date: 2007-03-28
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 全反射顕微鏡を利用した平滑筋Ca^<2+>誘発性Ca2÷遊離機構の可視化解析 (2007)
  • Author(s): 山村 寿男
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-16
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Visualization of Ca^<2+>-induced Ca^<2+> release in smooth muscle cells using total internal reflection fluorescence microscope (2007)
  • Author(s): Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Nagoya
  • Year and Date: 2007-03-16
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Kir2.1活性化による過剰な過分極は脳血管内皮細胞死を引き起こす (2007)
  • Author(s): 山崎 大樹
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-15
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] P19CL6細胞株の筋小胞体とミトコンドリアにおいて観察される自発性Ca^<2+>トランジェントの解析 (2007)
  • Author(s): 堀 優子
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-15
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 血管平滑筋におけるNa^+/Ca^<2+>交換輸送体の収縮調節機構への寄与 (2007)
  • Author(s): 村田 秀道
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-15
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ラット培養肺動脈平滑筋細胞におけるCa^<2+>活性化Clチャネルの機能発現 (2007)
  • Author(s): 井戸 田晴奈
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-15
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] The excess membrane hyperpolarization induced by Kir2.1 activation causes brain capillary endothelial cell death (2007)
  • Author(s): Daiju, Yamazaki, Hisao, Yamamura, Susumu, Ohya, Ktsuhiko, Muraki, Kiyofumi, Asai, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Nagoya
  • Year and Date: 2007-03-15
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Spontaneous Ca^<2+> transients fromsarcoplasmic reticulum and mitochondria in P19CL6 cells (2007)
  • Author(s): Yuko, Hori, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of TheJapanese Pharmacological Society
  • Place of Presentation: Nagoya
  • Year and Date: 2007-03-15
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Functional roles of Na+/Ca^<2+> exchanger on the regulation of Ca^<2+> activated K^+ channels in vascular smooth muscle (2007)
  • Author(s): Hidemichi, Murata, Hisao, Yamamura, Susumu, Ohya, Takahiro, Iwamoto, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Nagoya
  • Year and Date: 2007-03-15
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Functional expression of Ca^<2+> activated Cl channels in cultured smooth muscle cells of rat pulmonary artery (2007)
  • Author(s): Haruna, Itoda, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Nagoya
  • Year and Date: 2007-03-15
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Na^+/Ca^<2+>交換輸送体(NCX)過剰発現膀胱平滑筋における細胞内Ca^<2+>動態の変化 (2007)
  • Author(s): 堀田 真吾
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-14
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] DiBAC4(3)によるβサブユニット選択的BKチャネル活性化の分子機構 (2007)
  • Author(s): 森本 岳
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-14
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒスタミンはヒト由来軟骨肉腫細胞(OUMS-27)においてCa^<2+>活性化K^+チャネルによる過分極を引き起こす (2007)
  • Author(s): 舩橋 賢司
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-14
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒト前立腺癌におけるK^+及びCa^<2+>チャネル遺伝子発現 (2007)
  • Author(s): 大矢 進
  • Organizer: 第80回日本薬理学会年会
  • Place of Presentation: 名古屋
  • Year and Date: 2007-03-14
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Changes in Ca^<2+> mobilization in urinary bladder smooth muscle overexpressing Na+/ Ca^<2+> exchanger (NCX) (2007)
  • Author(s): Shingo, Hotta, Hidemichi, Murata, Hisao, Yamamura, Susumu, Ohya, Takahiro, Iwamoto, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Nagoya
  • Year and Date: 2007-03-14
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Molecular mechanism of 13 subunit-selective BK channel activation by DiBAC4(3) (2007)
  • Author(s): Takashi, Morimoto, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Nagoya
  • Year and Date: 2007-03-14
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Histamine induces membrane hyperpolarization via stimulation of Ca^<2+> activated K^+ channels in Human chondrosarcoma cell line (OUMS-27) (2007)
  • Author(s): Kenji, Funahashi, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Nagoya
  • Year and Date: 2007-03-14
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Expression of K^+ and Ca^<2+> channel genes in human prostate cancer (2007)
  • Author(s): Susumu, Ohya, Satomi, Niwa, Akitoshi, Ohno, Kojima, Shoichi, Sasaki, Kenjiro, Kohri, Yuji, Imaizumi
  • Organizer: The 80th Annual Meeting of the Pharmacological Society of Japan
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 2007-03-14
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] methyl-β-cyclodextrinの膀胱平滑筋におけるCICR機構への影響 (2006)
  • Author(s): 堀田 真吾
  • Organizer: 平成18年度日本薬学会東海支部例会
  • Place of Presentation: 名古屋
  • Year and Date: 2006-12-02
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] BKチャネルに対するオキソノール系化合物の構造と活性について (2006)
  • Author(s): 森本 岳
  • Organizer: 平成18年度日本薬学会東海支部例会
  • Place of Presentation: 名古屋
  • Year and Date: 2006-12-02
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 抗アンドロゲン剤の精管平滑筋K^+チャネル活性への影響 (2006)
  • Author(s): 大野 晃稔
  • Organizer: 平成18年度日本薬学会東海支部例会
  • Place of Presentation: 名古屋
  • Year and Date: 2006-12-02
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Effects of methyl-β-cyclodextrin on CICR mechanism in urinary bladder smooth muscle (2006)
  • Author(s): Shingo, Hotta, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: Tokai Brunch Meeting of The Japanese Pharmaceutical Society 2006
  • Place of Presentation: Nagoya
  • Year and Date: 2006-12-02
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Structure-activity of voltage-sensitive oxonol dyes as BK channel openers (2006)
  • Author(s): Takeshi, Morimoto, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: Tokai Brunch Meeting of The Japanese Pharmaceutical Society 2006
  • Place of Presentation: Nagoya
  • Year and Date: 2006-12-02
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Effects of anti-androgen drug on ion channel activity in rat vas deferens smooth muscle (2006)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: Tokai Brunch Meeting of The Japanese Pharmaceutical Society 2006
  • Place of Presentation: Nagoya
  • Year and Date: 2006-12-02
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 血管平滑筋におけるNa^+/Ca^<2+>交換輸送体の生理的意義の解明 (2006)
  • Author(s): 村田 秀道
  • Organizer: 第16回循環薬理学会
  • Place of Presentation: 東京
  • Year and Date: 2006-12-01
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Physiological roles of Na^+/Ca^<2+> exchanger in vascular smooth muscles (2006)
  • Author(s): Hidemichi, Murata, Hisao, Yamamura, Susumu, Ohya, Takahiro, iwamoto, Yuji, Imaizumi
  • Organizer: The 16th Annual Meeting of Japanese Associations of Cardiovascular Pharmacology
  • Place of Presentation: Tokyo
  • Year and Date: 2006-12-01
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] ラット精管平滑筋におけるテストステロンによる電位依存性K^+チャネル発現 (2006)
  • Author(s): 大矢 進
  • Organizer: 第110回日本薬理学会近畿部会
  • Place of Presentation: 京都
  • Year and Date: 2006-11-10
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 新規大コンダクタンスCa^<2+>活性化K^+チャネル開口薬の薬理学的解析と創薬への応用 (2006)
  • Author(s): 森本 岳
  • Organizer: 第110回日本薬理学会近畿部会
  • Place of Presentation: 京都
  • Year and Date: 2006-11-10
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Regulation of voltage-gated K^+ channel expression in rat vas deferens by testosterone (2006)
  • Author(s): Takasaki, Japan, Susumu, Ohya, Akitoshi, Ohno, Yuji, Imaizumi
  • Organizer: The 110th Kinki Branch Meeting of the Pharmacological Society of Japan in Kyoto
  • Place of Presentation: Kyoto
  • Year and Date: 2006-11-10
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Pharmacological analysis of novel large-conductance Ca^<2+> activated K^+ channel openers (2006)
  • Author(s): Takeshi, Morimoto, Kazuho, Sakamoto, Hiroko, Sade, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: The 110th Kinki Branch Meeting of the Pharmacological Society of Japan in Kyoto
  • Place of Presentation: Kyoto
  • Year and Date: 2006-11-10
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 男性ホルモンによる精管平滑筋K^+チャネル発現調節 (2006)
  • Author(s): 大矢 進
  • Organizer: 第34回薬物活性シンポジウム
  • Place of Presentation: 高崎
  • Year and Date: 2006-09-29
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Testosterone regulation of ion channel expression in vas deferens (2006)
  • Author(s): Susumu, Ohya, Akitoshi, Ohno, Satomi, Niwa, Katsutoshi, Ito, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: The 34th Symposium on Drug Activity
  • Place of Presentation: Takasaki, Japan
  • Year and Date: 2006-09-29
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Na^+/Ca^<2+>交換輸送体(NCX)過剰発現膀胱平滑筋における生理機能変化 (2006)
  • Author(s): 堀田 真吾
  • Organizer: 第48回日本平滑筋学会総会
  • Place of Presentation: 岡山
  • Year and Date: 2006-07-20
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Changes in physiological function in urinary bladder smooth muscles overexpressing Na^+/Ca^<2+> exchanger (NCX) (2006)
  • Author(s): Shingo, Hotta, Hidemichi, Murata, Hisao, Yamamura, Susumu, Ohya, Takahiro, Iwamoto, Yuji, Iwamoto
  • Organizer: The 48th Annual Meeting of Japan Society of Smooth Muscle Research
  • Place of Presentation: Okayama
  • Year and Date: 2006-07-20
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] The contribution of ryanodine receptor type 2 to E-C coupling and the regulation of resting tone in urinary bladder mvocvtes (2006)
  • Author(s): Shingo Hotta
  • Organizer: IUPHAR-15th World Congress of Pharmacology
  • Place of Presentation: Beijing, China
  • Year and Date: 2006-07-06
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] The contribution of ryanodine receptor type 2 to E℃ coupling and the regulation of resting tone in urinary bladder myocytes (2006)
  • Author(s): Shingo, Hotta, Kozo, Morimura, Susumu, Ohya, Katsuhiko, Muraki, Hiroshi, Takeshima, Yuji, Imaizumi
  • Organizer: IUPHAR -15th World Congress of Pharmacology-
  • Place of Presentation: Beijing, China
  • Year and Date: 2006-07-06
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Sarcoplasmic reticulum and membrane events in smooth muscle cells (2006)
  • Author(s): Yuji Imaizumi
  • Organizer: IUPHAR-15th World Congress of Pharmacology
  • Place of Presentation: Beijing, China
  • Year and Date: 2006-07-04
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Two different types of K^+ channels regulated cell proliferation and cell death in bovine brain endothelial cells (2006)
  • Author(s): Daiju Yamazaki
  • Organizer: IUPHAR-15th World Congress of Pharmacology
  • Place of Presentation: Beijing, China
  • Year and Date: 2006-07-04
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Sarcoplasmic reticulum and membrane events in smooth muscle cells [Invited Speaker] (2006)
  • Author(s): Yuji, Imaizumi
  • Organizer: IUPHAR -15th World Congress of Pharmacology-
  • Place of Presentation: Beijing, China
  • Year and Date: 2006-07-04
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Two different types of K^+ channels regulated cell proliferation and cell death in bovine brain endothelial cells (2006)
  • Author(s): Daiju, Yamazaki, Susumu, Ohya, Katsuhiko, Muraki, Kiyofumi, Asai, Yuji, Imaizumi
  • Organizer: IUPHAR -15th World Congress of Pharmacology-
  • Place of Presentation: Beijing, China
  • Year and Date: 2006-07-04
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] フルタミドによる精管平滑筋K^+チャネル機能変化 (2006)
  • Author(s): 大野 晃稔
  • Organizer: 第109回日本薬理学会近畿部会
  • Place of Presentation: 倉敷
  • Year and Date: 2006-06-16
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] マウス大動脈平滑筋細胞におけるNa^+/Ca^<2+>交換輸送体の電気生理学的解析 (2006)
  • Author(s): 村田 秀道
  • Organizer: 第109回日本薬理学会近畿部会
  • Place of Presentation: 倉敷
  • Year and Date: 2006-06-16
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Effects of flutamide on functional properties of vas deferens ion channels (2006)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Hisao, Yamamura, Yuji, Imaizumi
  • Organizer: The 109th Kinki Branch Meeting of The Pharmacological Society of Japan In Kurashiki
  • Place of Presentation: Kurashiki
  • Year and Date: 2006-06-16
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Electrophysiological analysis of Na+/Ca+2+ exchanger in murine aortic smooth muscle cells (2006)
  • Author(s): Hidemichi, Murata, Hisao, Yamamura, Susumu, Ohya, Takahiro, Iwamoto, Yuji, Imaizumi
  • Organizer: The 109th Kinki Branch Meeting of The Pharmacological Society of Japan In Kurashiki
  • Place of Presentation: Kurashiki
  • Year and Date: 2006-06-16
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] ピマル酸による電位依存性K^+チャネル開口作用と結合部位の探索 (2006)
  • Author(s): 坂本 多穂
  • Organizer: 日本薬学会第126年会
  • Place of Presentation: 仙台
  • Year and Date: 2006-03-30
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Identification and functional characterization of pimaric actid binding motifs involving in voltage-gated K^+ channel opening (2006)
  • Author(s): Kazuho, Sakamoto, Susumu, Ohya, Katsuhiko, Muraki, Tomohiko, Ohwada, Yuji, Imaizumi
  • Organizer: The 126th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Sendai
  • Year and Date: 2006-03-30
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 中コンダクタンスCa^<2+>活性化K^+チャネルにおける開口薬結合部位の同定 (2006)
  • Author(s): 柳 文乃
  • Organizer: 日本薬学会第126年会
  • Place of Presentation: 仙台
  • Year and Date: 2006-03-29
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Molecular identification of binding domains of intermediate-conductance Ca^<2+> -activated K^+ channel openers (2006)
  • Author(s): Ayano, Yanagi, Satomi, Niwa, Hisao, Yamamura, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 126th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Sendai
  • Year and Date: 2006-03-29
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] ヒトHCN3チャネルの酸性pHによる活性化 (2006)
  • Author(s): 山村 寿男
  • Organizer: 日本薬学会第126年会
  • Place of Presentation: 仙台
  • Year and Date: 2006-03-28
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Activation of the human HCN3 channel by acidic pH (2006)
  • Author(s): Hisao, Yamamura, Naomi, Itazu, Yoko, Matsuoka, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 126th Annual Meeting of The Pharmaceutical Society of Japan
  • Place of Presentation: Sendai
  • Year and Date: 2006-03-28
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 電位依存性Ca^<2+>チャネルβ3サブユニット欠損マウスの平滑筋における中コンダクタンスCa^<2+>活性化K^+チャネルの発現低下 (2006)
  • Author(s): 森村 浩三
  • Organizer: 第79回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 去勢ラット精管平滑筋における大コンダクタンスCa^<2+>活性化K^+チャネル減少の自発収縮への影響 (2006)
  • Author(s): 大野 晃稔
  • Organizer: 第79回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Jurkat細胞における小コンダクタンスCa^<2+>活性化K^+チャネルの細胞周期に伴う機能調節 (2006)
  • Author(s): 森本 岳
  • Organizer: 第79回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ピマル酸による電位依存性K^+チャネルの制御と結合領域の推定 (2006)
  • Author(s): 坂本 多穂
  • Organizer: 第79回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ヒトHCN3チャネルのpH感受性 (2006)
  • Author(s): 山村 寿男
  • Organizer: 第79回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Down-regulation of intermediate conductance Ca^<2+> activated K^+ channel in smooth muscle of voltage dependent Ca2+ channel(32)subunit deficient mouse (2006)
  • Author(s): Kozo, Morimura, Susumu, Ohya, Hisao, Yamamura, Manabu, Murakami, katsuhiko, muraki, Kazuo, Nunoki, Teruyuki, Yanagisawa, Yuji, Imaizumi
  • Organizer: The 79th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] The regulation of large conductance Ca^<2+> -activated K^+ channel expressions brings spontaneous contractions in vas deference from castrated-rat (2006)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: The 79th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Cell-cycle dependent regulation of small-conductance Ca^<2+> -activated K^+ channel activity in Jurkat T-lymphocytes (2006)
  • Author(s): Takeshi, Morimoto, Susumu, Ohya, Hidetoshi, Hayashi, Katsuhiko, Muraki, Kikuo, Onozaki, Yuji, Imaizumi
  • Organizer: The 79th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Pimaric acid modulate, voltage-gated K^+ channels by binding its activation gate (2006)
  • Author(s): Kazuho, Sakamoto, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: The 79th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Activation of the human HCN3 channel by acidic pH (2006)
  • Author(s): Hisao, Yamamura, Naomi, Itazu, Yoko, Matsuoka, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 79th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2006-03-10
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] ラット大動脈平滑筋細胞における細胞内Ca^<2+>濃度と膜電流へのTrpV4活性化薬である4α-phorbol12, 13-didecanoateの影響 (2006)
  • Author(s): 田中 良一
  • Organizer: 第79回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2006-03-09
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Effects of 4a-Phorbol 12,13-dide-canoate, a potent activator of Trpv4, on intracellular Ca^<2+> concentration and membrane currents in rat aortic myocytes (2006)
  • Author(s): Ryoichi, Tanaka, Katsuhiko, Muraki, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 79th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2006-03-09
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 膀胱平滑筋における2型リアノジン受容体を介したCa^<2+>動態の解明 (2006)
  • Author(s): 堀田 真吾
  • Organizer: 第79回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2006-03-08
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ウシ脳血管内皮細胞において内向き整流性K^+チャネルは細胞死を制御する (2006)
  • Author(s): 山崎 大樹
  • Organizer: 第79回日本薬理学会年会
  • Place of Presentation: 横浜
  • Year and Date: 2006-03-08
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Ca^<2+> mobilization via ryanodine receptor type 2 in urinary bladder smooth muscle (2006)
  • Author(s): Shingo, Hotta, Kozo, Morimura, Susumu, Ohya, Katsuhiko, Muraki, Hiroshi, Takeshima, Yuji, Imaizumi
  • Organizer: The 79th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2006-03-08
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Inward rectifier K^+ channel regulates cell death in bovine capillary endothelial cells (2006)
  • Author(s): Daiju, Yamazaki, Susumu, Ohya, Katsuhiko, Muraki, Kiyofumi, Asai, Yuji, Imaizumi
  • Organizer: The 79th Annual Meeting of The Japanese Pharmacological Society
  • Place of Presentation: Yokohama
  • Year and Date: 2006-03-08
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Involvement of IP_3 formation in voltage-dependent regulation of Ca^<2+> concentration in coronary arterial smooth muscle cells (2006)
  • Author(s): Hisao Yamamura
  • Organizer: Biophysical Society-50th Annual Meeting
  • Place of Presentation: Salt Lake City, USA
  • Year and Date: 2006-02-22
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Involvement of IP_3 formation in voltage-dependent regulation of Ca^<2+> concentration in coronary arterial smooth muscle cells (2006)
  • Author(s): Hisao, Yamamura, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: Biophysical Society -50th Annual Meeting-
  • Place of Presentation: Salt Lake City, USA
  • Year and Date: 2006-02-22
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Testosterone regulates the large-conductance Ca^<2+>-activated K^+ channel expression in ratvas deferens smooth muscle cells (2006)
  • Author(s): Akitoshi Ohno
  • Organizer: Biophysical Society-50th Annual Meeting
  • Place of Presentation: Salt Lake City, USA
  • Year and Date: 2006-02-19
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Testosterone regulates the large-conductance Ca^<2+>-activated K^+ channel expression in rat vas deferens smooth muscle cells (2006)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: Biophysical Society -50th Annual Meeting-
  • Place of Presentation: Salt Lake City, USA
  • Year and Date: 2006-02-19
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] マウス大動脈平滑筋細胞におけるNa^+/Ca^<2+>交換輸送体の機能解析 (2006)
  • Author(s): 村田 秀道
  • Organizer: 生体機能と創薬シンポジウム
  • Place of Presentation: 福岡
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] The contribution of inward-rectifier Kir2.1 K^+ channel regulation in the mechanisms underlying the brain endothelial cell death by excess ATP (2006)
  • Author(s): Daiju, Yamazaki, Susumu, Ohya, katsuhiko, Muraki, Kiyofumi, Asai, Yuji, Imaizumi
  • Organizer: Biofunction and Drug Discovery Symposium 2006
  • Place of Presentation: Fukuoka
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Physiologycal roles of Na^+/Ca^<2+> exchanger in mouse aorta smooth muscle cells (2006)
  • Author(s): Hidemichi, Murata, Hisao, Yamamura, Susumu, Ohya, Takahiro, Iwamoto, Yuji, Imaizumi
  • Organizer: Biofunction and Drug Discovery Symposium 2006
  • Place of Presentation: Fukuoka
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] A New Insight into the Function of TRPV2 in Circulatory Organs (2006)
  • Author(s): Katsuhiko, Muraki, Munekazu, Shigekawa, Yuji, Imaizumi
  • Organizer: TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades (Frontiers in Neuroscience) (Wolfgang B. Liedtke, ed.), Chapter 28
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 電位依存性Ca^<2+>チャネルβ3サブユニット欠損マウスにおける平滑筋での中コンダクタンスCa^<2+>活性化K^+チャネルの発現変化 (2005)
  • Author(s): 森村 浩三
  • Organizer: 平成17年度日本薬学会東海支部例会
  • Place of Presentation: 名古屋
  • Year and Date: 2005-12-03
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Changes in intermediate-conductance Ca^<2+> -activated K^+ channel expression in smooth muscles of voltage-gated Ca^<2+> channel β3 subunit null mice (2005)
  • Author(s): Kozo, Morimura, Susumu, Ohya, Hisao, Yamamura, Manabu, Murakami, Katsuhiko, Muraki, Kazuo, Nunoki, Teruyuki, Yanagisawa, Yuji, Imaizumi
  • Organizer: Tokai Brunch Meeting of The Japanese Pharmaceutical Society 2005
  • Place of Presentation: Nagoya
  • Year and Date: 2005-12-03
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Twotypes of K^+ channel regulate cell proliferation and damage in bovine brain capillary endothelial cells (2005)
  • Author(s): Daiju Yamazaki
  • Organizer: Neuroscience 2005-SfN 35th Annual Meeting
  • Place of Presentation: Washington DC, USA
  • Year and Date: 2005-11-16
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Two types of K^+ channel regulate cell proliferation and damage in bovine brain capillary endothelial cells (2005)
  • Author(s): Daiju, Yamazaki, Mineyoshi, Aoyama, Susumu, Ohya, Katsuhiko, Muraki, Kiyofumi, Asai, Yuji, Imaizumi
  • Organizer: Neuroscience 2005 -SfN 35th Annual Meeting-
  • Place of Presentation: Washington DC, USA
  • Year and Date: 2005-11-16
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] P19CL6胚性腫瘍細胞における心筋分化に伴う細胞内Ca^<2+>シグナル制御機構の変化 (2005)
  • Author(s): 堀 優子
  • Organizer: 生体機能と創薬シンポジウム2005
  • Place of Presentation: 広島
  • Year and Date: 2005-09-08
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 消化管ペースメーカー細胞モデルの構築-リアノジン受容体とCa^<2+>活性化K^+チャネルの共発現系を用いて (2005)
  • Author(s): 木村 泰介
  • Organizer: 生体機能と創薬シンポジウム2005
  • Place of Presentation: 広島
  • Year and Date: 2005-09-08
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 心筋ミトコンドリアにおけるBKチャネルβ1サブユニットの発現とBKチャネル開口薬による心筋細胞保護作用 (2005)
  • Author(s): 大矢 進
  • Organizer: 生体機能と創薬シンポジウム2005
  • Place of Presentation: 広島
  • Year and Date: 2005-09-08
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Changes in functional expression of voltage-dependent Ca^<2+> channel and the ryanodine receptor during cardiac myocytes differentiation in P19CL6 cells (2005)
  • Author(s): Yuko, Hori, Kaori, Kato, Asuka, Ogawa, Kozo, Morimura, Shingo, Hotta, Hisao, Yamamura, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: Biofunction and Drug Discovery Symposium 2005
  • Place of Presentation: Hiroshima
  • Year and Date: 2005-09-08
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Imaizumi A model for electrical pacemaker cells of the gut〜Functional coupling between ryanodine receptor and Ca^<2+>-activated K^+ channel〜 (2005)
  • Author(s): Taisuke, Kimura, Hisao, Yamamura, Aid, Yamada, Takayo, Goto, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: Biofunction and Drug Discovery Symposium 2005
  • Place of Presentation: Hiroshima
  • Year and Date: 2005-09-08
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Expression of BK channel β1 subunit in cardiac mitochondria and cardioprotective effects of BK channel openers (2005)
  • Author(s): Susumu, Ohya, Kazuho, Sakamoto, Yukiko, Kuwata, Katsuhiko, Muraki, Tomohiko, Ohwada
  • Organizer: Biofunction and Drug Discovery Symposium 2005
  • Place of Presentation: Hiroshima, Japan
  • Year and Date: 2005-09-08
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Two step mechanism of induced release in excitation-contraction coupling (2005)
  • Author(s): Yuji Imaizumi
  • Organizer: University of Oxford Meeting on Ion channels, genes and regulation in smooth muscle
  • Place of Presentation: Oxford. UK
  • Year and Date: 2005-09-06
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Two step mechanism of Ca^<2+> induced Ca^<2+> release in excitation-contraction coupling [Invited Speaker] (2005)
  • Author(s): Yuji, Imaizumi
  • Organizer: University of Oxford Meeting on Ion channels, genes and regulation in smooth muscle.
  • Place of Presentation: Oxford. UK
  • Year and Date: 2005-09-06
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Physiological functions of ryanodine receptor type2 (RyR2) at resting state and during excitation-contraction coupling in urinary bladder smooth muscle (2005)
  • Author(s): Shingo Hotta
  • Organizer: University of Oxford Meeting on Ion channels, genes and regulation in smooth muscle
  • Place of Presentation: Oxford. UK
  • Year and Date: 2005-09-05
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Physiological functions of ryanodine receptor type 2 (RyR2) at resting state and during excitation-contraction coupling in urinary bladder smooth muscle (2005)
  • Author(s): Shingo, Hotta, Kozo, Morimura, Susumu, Ohya, Katsuhiko, Muraki, Hiroshi, Takeshima, Yuji, Imaizumi
  • Organizer: University of Oxford Meeting on Ion channels, genes and regulation in smooth muscle.
  • Place of Presentation: Oxford. UK
  • Year and Date: 2005-09-05
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Large-conductance Ca^<2+>-activated K^+ channel β1 subunit in cardiac mitochondria and cardioprotective effects of BK channel openers (2005)
  • Author(s): SusumuOhya
  • Organizer: US-Japan Conference on Drug Development & Rational Drug Design
  • Place of Presentation: Los Angels, USA
  • Year and Date: 2005-08-02
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Testosterone regulation of large-conductance Cat^<2+>-activated K^+ channel expression in ratvas deferens smooth muscle cells (2005)
  • Author(s): Akitoshi Ohn
  • Organizer: US-Japan Conference on Drug Development & Rational Drug Design
  • Place of Presentation: Los Angels, USA
  • Year and Date: 2005-08-02
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Testosterone regulation of large-conductance Ca^<2+>-activated K^+ channel expression in rat vas deferens smooth muscle cells (2005)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: US-Japan Conference on Drug Development & Rational Drug Design
  • Place of Presentation: Los Angels, USA
  • Year and Date: 2005-08-02
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] ウシ脳血管内皮細胞におけるSOCの特性 (2005)
  • Author(s): 山崎 大樹
  • Organizer: 第28回日本神経科学大会
  • Place of Presentation: 横浜
  • Year and Date: 2005-07-28
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Roles of SOC in bovine brain endothelial cells (2005)
  • Author(s): Daiju, Yamazaki, Susumu, Ohya, Katsuhiko, Muraki, Kiyofumi, Asai, Yuji, Imaizumi
  • Organizer: The 28th Annual Meeting of the Japan Neuroscience Society
  • Place of Presentation: Yokohama
  • Year and Date: 2005-07-28
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 脂質メディエーターによる血管の機能調節と臨床応用 (2005)
  • Author(s): 村木 克彦
  • Organizer: 第47回日本平滑筋学会総会
  • Place of Presentation: 仙台
  • Year and Date: 2005-07-08
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 膀胱平滑筋収縮時におけるRyR2機能の重要性 (2005)
  • Author(s): 堀田 真吾
  • Organizer: 第47回日本平滑筋学会総会
  • Place of Presentation: 仙台
  • Year and Date: 2005-07-08
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Functional regulation of vasculacture by lipid mediators and their clinical use [Symposium] (2005)
  • Author(s): Katsuhiko, Muraki, Susumu, Ohya, Yuji, Imaizumi
  • Organizer: The 47th Annual Meeting of Japan Society of Smooth Muscle Research
  • Place of Presentation: Sendai
  • Year and Date: 2005-07-08
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Significance of RyR2 in EC coupling in urinary bladder (2005)
  • Author(s): Shingo, Hotta, Kozo, Morimura, Susumu, Ohya, Katsuhiko, Muraki, Hiroshi, Takeshima, Yuji, Imaizumi
  • Organizer: The 47th Annual Meeting of Japan Society of Smooth Muscle Research
  • Place of Presentation: Sendai
  • Year and Date: 2005-07-08
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] ラット大動脈平滑筋細胞に対するEDG受容体活性化薬の効果とEDG受容体の発現変化 (2005)
  • Author(s): 田中 良一
  • Organizer: 第47回日本平滑筋学会総会
  • Place of Presentation: 仙台
  • Year and Date: 2005-07-07
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Effects of EDG receptor activators in rat aortic smooth muscle cells and changes in expression of EDG receptors by them (2005)
  • Author(s): Ryoichi, Tanaka, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: The 47th Annual Meeting of Japan Society of Smooth Muscle Research
  • Place of Presentation: Sendai
  • Year and Date: 2005-07-07
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 新規大コンダクタンスCa^<2+>活性化K^+チャネル開口薬による虚血心筋保護機構の解明 (2005)
  • Author(s): 坂本 多穂
  • Organizer: 平成17年度日本薬学会東海支部会例会
  • Place of Presentation: 岐阜
  • Year and Date: 2005-07-02
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Mechanisms for cardioprotective effects of a novel opener of large-conductance Ca^<2+>-activated K^+ channels (2005)
  • Author(s): Kazuho, Sakamoto, Susumu, Ohya, Katsuhiko, Muraki, Tomohiko, Ohwada, Yuji, Imaizumi
  • Organizer: Tokai Brunch Meeting of The Japanese Pharmaceutical Society in 2005
  • Place of Presentation: Gifu
  • Year and Date: 2005-07-02
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 去勢ラット精管平滑筋におけるK^+チャネル発現変化 (2005)
  • Author(s): 大野 晃稔
  • Organizer: 第107回日本薬理学会近畿部会
  • Place of Presentation: 金沢
  • Year and Date: 2005-06-24
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ラット大動脈初代培養平滑筋細胞におけるEDG受容体の発現変化 (2005)
  • Author(s): 田中 良一
  • Organizer: 第107回日本薬理学会近畿部会
  • Place of Presentation: 金沢
  • Year and Date: 2005-06-24
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Changes in ion channel expression in vas deferens smooth muscles of castrated rats (2005)
  • Author(s): Akitoshi, Ohno, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: The 107th Kinki Branch Meeting of The Japanese Pharmacological Society In Kanazawa
  • Place of Presentation: Kanazawa
  • Year and Date: 2005-06-24
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Changes in EDG receptor expressions in rat aortic smooth muscle cells in primary culture (2005)
  • Author(s): Ryoichi, Tanaka, Susumu, Ohya, Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: The 107th Kinki Branch Meeting of The Japanese Pharmacological Society In Kanazawa
  • Place of Presentation: Kanazawa
  • Year and Date: 2005-06-24
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 2型リアノジン受容体異型接合型欠損マウス膀胱平滑筋におけるCa^<2+>働態の変化 (2005)
  • Author(s): 堀田 真吾
  • Organizer: 第82回日本生理学会年会
  • Place of Presentation: 仙台
  • Year and Date: 2005-05-18
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Intracellular Ca^<2+> mobilization in urinary bladder of RyR2 heterozygous KO mice (2005)
  • Author(s): Shingo, Hotta, Kozo, Morimura, Susumu, Ohya, Katsuhiko, Muraki, Hiroshi, Takeshima, Yuji, Imaizumi
  • Organizer: The 82nd Annual Meeting of The Physiological Society of Japan
  • Place of Presentation: Sendai
  • Year and Date: 2005-05-18
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Novel mechanism for enhancement of Ca^<2+> response to ATP in bovine brain capillary endothelial cells (2005)
  • Author(s): Yuji Imaizumi
  • Organizer: The 35th Congress of the International Union of Physiological Sciences(IUPS)
  • Place of Presentation: SanDiego, USA
  • Year and Date: 2005-04-03
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Novel mechanism for enhancement of Ca^<2+> response to ATP in bovine brain capillary endothelial cells (2005)
  • Author(s): Yuji, Imaizumi, Daiju, Yamazaki, Mineyoshi, Aoyama, Susumu, Ohya, Katsuhiko, Muraki, Kiyofumi, Asai
  • Organizer: The 35th Congress of the International Union of Physiological Sciences (IUPS)
  • Place of Presentation: San Diego, USA
  • Year and Date: 2005-04-03
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 7. Ca^<2+> Releasing Channels in Pulmonary Vascular Smooth Muscle Cells (2005)
  • Author(s): Yuji, Imaizumi, Katsuhiko, Muraki
  • Organizer: Ion Channels in the Pulmonary Vasculature
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Ion channels in vascular smooth muscle cells and remodeling (2005)
  • Author(s): Katsuhiko, Muraki, Yuji, Imaizumi
  • Organizer: Recent Progress in Ion Channel Reserch-update
  • Description: 「研究成果報告書概要(欧文)」より
• [Book] A new insight into the function of TRPV2 in circulatory organs TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades(Frontiers in Neuroscience)(Wolfgang B. Liedtke, ed.), Chapter 28 (2006)
  • Author(s): Muraki K
  • Publisher: CRC Press
  • Description: 「研究成果報告書概要(和文)」より
• [Book] A new insight into the function of TRPV2 in circulatory organs. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades (Frontiers in Neuroscience)(Wolfgang B. Liedtke, ed.), Chapter 28 (2006)
  • Author(s): Muraki K, Shigekawa M, Imaizumi Y
  • Publisher: CRC Press
• [Book] Ca^<2+> Releasing Channels in Pulmonary Vascular Smooth Muscle Cells Ion Channels in the Pulmonary Vasculature, Chapter7 (2005)
  • Author(s): Yuji Imaizumi
  • Publisher: CRC Press
  • Description: 「研究成果報告書概要(和文)」より
• [Book] 血管平滑筋細胞イオンチャネルとリモデリング(改訂)別冊・医学のあゆみ (2005)
  • Author(s): 村木 克彦
  • Publisher: 医歯薬出版
  • Description: 「研究成果報告書概要(和文)」より
• [Book] Ca^<2+> releasing channels in pulmonary vascular smooth muscle cells (Ion channels in the pulmonary vasculature, edited by Yuan Jason X.-J.) (2005)
  • Author(s): Imaizumi Y, Muraki K.
  • Publisher: Marcel Dekker Inc
• [Book] 血管平滑筋細胞イオンチャネルとリモデリング(イオンチャネル最前線update、倉智嘉久編集) (2005)
  • Author(s): 村木克彦, 今泉祐治
  • Publisher: 医歯薬出版
• [Remarks] 「研究成果報告書概要(和文)」より
  • URL: http://www.phar.nagoya-cu.ac.jp/hp/ysg/index.html
• [Remarks]
  • URL: http://www.phar.nagoya-cu.ac.jp/hp/ysg/index.html
• [Patent(Industrial Property Rights)] カリウムチャネル開口薬 (2007)
  • Inventor(s): 今泉 祐治, 大矢 進, 森本 岳
  • Industrial Property Rights Holder: 有限会社チャネロサーチテクノロジー
  • Industrial Property Number: 2007-108474
  • Filing Date: 2007-04-17
  • Description: 「研究成果報告書概要(和文)」より
• [Patent(Industrial Property Rights)] カリウムチャネル開口薬 (2007)
  • Inventor(s): 今泉祐治, 大矢 進, 森本 岳
  • Industrial Property Rights Holder: 有限会社チャネロサーチテクノロジー
  • Industrial Property Number: 2007-108474
  • Filing Date: 2007-04-17