| Co-Investigator(Kenkyū-buntansha) |
TAMAKOSHI Koji Nagoya University, Graduate School of Medicine, Associate Professor, 大学院医学系研究, 助教授 (30262900)
YATSUYA Hiroshi Nagoya University, Graduate School of Medicine, Associate Professor, 大学院医学系研究, 助教授 (30324437)
KONDO Takaaki Nagoya University, School of Medicine, Associate Professor, 医学部, 助教授 (00195900)
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| Budget Amount *help |
¥4,700,000 (Direct Cost: ¥4,700,000)
Fiscal Year 2006: ¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2005: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Research Abstract |
Based on the data of questionnaire survey of the workers' lifestyles in 1997 and 2002, effects of perceived mental stress on cardiovascular risk factors were analyzed
1. Among four choices of answers, i.e., "very much", "much", "ordinary", and "little" to the question "Do you have much stress in your life?," the proportional rates of 6 items of job strain, overwork, sleep and exercise habits, and presence of confidants were compared and statistically significant, reasonable relationships were obtained in men (n=5,159) and women (n=1,468).
2. In 1,062 male workers, serum leptin concentration was shown to increase significantly along with the increase of perceived stress after age, BMI, and lifestyles were statistically adjusted.
3. The effects of perceived stress and physique of five years duration on blood pressure were examined in 1,673 male workers. In the 2 way ANOVA, main effect of physique and interaction between stress were significant. In the group which kept obese, both systolic a
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nd diastolic blood pressure became higher along with the increase of stress, while they became lower in the group which kept normal or lean weight.
4. In 2,144 male workers, compared with the group which perceived lesser stress and did not eat to satiety, the increment of BMI during five years was not significant in the groups in which either one of much stress or satiety eating was present, but was significant in the group both factors were present after age, BMI in 1997, and exercise, smoking, and drinking habits were adjusted. The proportion of satiety eater became significantly greater as the perceived stress became greater.
5. In January of 2007, developments of lifestyle-related diseases were surveyed by self-administered questionnaire in 11,256 workers and 671 people who retired. Analyses to investigate factors developing diseases will be done.
6. Relationship between leptin concentration and blood pressure and the role of adiponectin in the development of metabolic syndrome were examined. Less
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