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Evaluation of aging through oxidative stress and anti-oxidant potential in Mongolian people, and anti-aging expedient for Japanese people

Research Project

Project/Area Number 17406006
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Environmental physiology (including Physical medicine and Nutritional physiology)
Research InstitutionKagawa Nutrition University

Principal Investigator

KAGAWA Yasuo  Kagawa Nutrition University, 栄養学部, 教授 (30048962)

Co-Investigator(Kenkyū-buntansha) KOMATSU Fumio  女子栄養大学, 栄養学部, 教授 (10014250)
金子 嘉徳  女子栄養大学, 栄養学部, 教授 (20204571)
川端 輝江  女子栄養大学, 栄養学部, 教授 (80190932)
渡邊 早苗  女子栄養大学, 栄養学部, 教授 (00076184)
佐久間 充  女子栄養大学, 栄養科学研究所, 客員研究員 (90010066)
工藤 秀機 (工藤 秀樹)  女子栄養大学, 栄養学部, 教授 (90114751)
Co-Investigator(Renkei-kenkyūsha) KANEKO Yoshinori  女子栄養大学, 栄養学部, 教授 (20204571)
KAWABATA Terue  女子栄養大学, 栄養学部, 教授 (80190932)
WATANABE Sanae  女子栄養大学, 栄養学部, 教授 (00076184)
SAKUMA Mitsuru  女子栄養大学, 栄養科学研究所, 客員研究員 (90010066)
KUDOH Hideki  文京学院大学, 保健医療技術学部, 教授 (90114751)
Project Period (FY) 2005 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥5,750,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2007: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2006: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 2005: ¥3,500,000 (Direct Cost: ¥3,500,000)
Keywordsモンゴル人 / 老化 / 酸化ストレス / 抗酸化能 / 生活習慣 / モンゴル / 酸化ストレス度 / 老化・抗老化 / 平均寿命 / 微量金属 / マンガン / 食事調査 / 抗酸化食品 / 血清脂質 / 野菜食 / d-ROMテスト / DHA / 握力 / SOD活性
Research Abstract

モンゴル人は日本人に比べ平均寿命が男女とも15 年以上短い。その理由を知るためにモンゴル人の健康調査を行った。モンゴル人は食生活に偏りがあり、肉食が主で野菜や果物は少なく、酸化ストレスが高く、老化の訪れが早かった。彼らの短寿命を解決するにはこれらの改善が重要であり、日本人の老化を考える上でモンゴル人の食生活と高い酸化ストレス度は重要な警鐘と思われた。

Report

(5 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (25 results)

All 2009 2008 2007 2006 2005 Other

All Journal Article (11 results) (of which Peer Reviewed: 9 results) Presentation (14 results)

  • [Journal Article] The association of very high hair manganese accumulation and high oxidative stress in Mongolian people2009

    • Author(s)
      Fumio Komatsu, Yasuo Kagawa, Kiyomi Ishiguro, Terue Kawabata, Baatar Purvee, Jugder Otgon and Ulziiburen Chimedregzen
    • Journal Title

      Current Aging Sci. 2

      Pages: 28-42

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] The association of very high hair manganese accumulation and high oxidative stress in Mongolian people.2009

    • Author(s)
      F. Komatsu, Y. Kagawa, et al
    • Journal Title

      Current Aging Science 2

      Pages: 28-42

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship of dietary habits and obesity to oxidative stress in Palauan people : compared with Japanese and Mongolian people.2009

    • Author(s)
      F. Komatsu, Y. Kagawa, et al
    • Journal Title

      Current Aging Science (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dietary habits of Mongolian people, and their influence on lifestyle-related diseases and early aging2008

    • Author(s)
      Fumio Komatsu, Yasuo Kagawa, Terue Kawabata, Yoshinori Kaneko, Baatar Purvee,Jugder Otgon and Ulziiburen Chimedregzen
    • Journal Title

      Current Aging Sci. 1

      Pages: 84-100

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dietary habits of Mongolian people, and their in fluence on lifestyle-related diseases and early aging.2008

    • Author(s)
      F. Komatsu, Y. Kagawa, et al
    • Journal Title

      Current Aging Science 1

      Pages: 84-100

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dietary habits of Mongolian people,and their influence on lifestyle-related diseases and early aging2008

    • Author(s)
      F.Komatsu, Y.Kagawa, et. al.
    • Journal Title

      Current Aging Science 1(in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of oxidative stress and effectiveness of low-dose glucocorticoid therapy on exacerbation of chronic obstructive pulmonary disease2007

    • Author(s)
      F.Komatsu, H.Kudoh, Y.Kagawa
    • Journal Title

      J.Gerontology:Medical Sciences 62A

      Pages: 459-464

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of oxidative stress and effectiveness of low-dose corticosteroid therapy on exacerbation of chronic obstructive pulmonary disease2007

    • Author(s)
      Fumio Komatsu
    • Journal Title

      J. Gerontology : Medical Sciences (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Investigation of oxidative stress and dietary habits in Mongolian people, compared to Japanese people2006

    • Author(s)
      Fumio Komatsu, Yasuo Kagawa, Mitsuru Sakuma, Terue Kawabata, Yoshinori Kaneko, Dugee Otgontuya, Ulziiburen Chimedregzen, Luvsanbazar Narantya and Baatar Purvee
    • Journal Title

      Nutr. Metabol. 3

    • URL

      http://www.nutritionandmetabolism.com/content/3/1/21

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Investigation of oxidative stress and dietary habits in Mongolian people, compared to Japanese people.2006

    • Author(s)
      Fumio Komatsu
    • Journal Title

      Nutrition & Metabolism http://www.nutritionandmetabolism. com/content/3/1/21 3

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Relationship of dietary habits and obesity to oxidative stress in Palauan people: compared with Japanese and Mongolian people

    • Author(s)
      Fumio Komatsu, Yasuo Kagawa, Terue Kawabata, Yoshinori Kaneko, Kiyomi Ishiguro
    • Journal Title

      Current aging Sci.(in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] Influence of dietary habits on lifestyle- related diseases and early aging in Mongolian people2008

    • Author(s)
      Komatsu, F., Kagawa, Y., Purvee, B., Ulziiburen, C.
    • Organizer
      40^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Related Report
      2008 Final Research Report
  • [Presentation] Clinical effectiveness of electrolyzed reduction water (ERW, which has strong reductive potential) on several diseases (3^<rd> report).2008

    • Author(s)
      Osada, S., Komatsu, F., Komatsu, M., Kagawa, Y.
    • Organizer
      40^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Related Report
      2008 Final Research Report
  • [Presentation] Influence of dietary habits on lifestyle-related diseases and early aging in Mongolian people.2008

    • Author(s)
      F. Komatsu, Y. Kagawa, et al
    • Organizer
      40^<th> Conference of Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Related Report
      2008 Annual Research Report
  • [Presentation] Comparison of life style and oxidative stress among Mongolian,Palauan and Japnaese people.2007

    • Author(s)
      F.Komatsu, Y.Kagawa, et. al.
    • Organizer
      39th Conference of Asia-Pacific Academic Consortiumfor Public Health
    • Place of Presentation
      Saitama,Japan
    • Year and Date
      2007-11-23
    • Related Report
      2007 Annual Research Report
  • [Presentation] Sodbileg, D., Komatsu, M., Osada, S.2007

    • Author(s)
      Komatsu, F.
    • Organizer
      Anti-oxidant potential in blood after eating of anti-oxidant foods. 39^<th> Asia-Pacific Academic Consortium for Public Health
    • Related Report
      2008 Final Research Report
  • [Presentation] Early aging, dietary habits and oxidative stress in Mongolian people.2007

    • Author(s)
      Sodbileg, D., Komatsu, F., Sakuma, M., Kaneko, Y., Kawabata, T., Ishiguro, K.
    • Organizer
      39^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Saitama, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Effectiveness of electrolyzed reductive water (ERW) with strong reduction potential on several diseases2007

    • Author(s)
      Osada, S., Komatsu, M., Komatsu, F.
    • Organizer
      39^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Saitama, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Genotype of manganese superoxide dismutase polymorphism of Mongolian people is associated with their short life span.2007

    • Author(s)
      Fukushima, A., Komatsu, F., Sakuma, K., Kagawa, Y.
    • Organizer
      39^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Saitama, Japan
    • Related Report
      2008 Final Research Report
  • [Presentation] Comparison of reactive oxygen species among the people of the Republic of Palau, Mongolia and Japan2006

    • Author(s)
      Komatsu, F., Kagawa, Y., Sakuma, M., Kaneko, Y., Kawabata, T.
    • Organizer
      38^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Bangkok, Thailand
    • Related Report
      2008 Final Research Report
  • [Presentation] Effectiveness of electrolyzed water with high reduction potential on human health2006

    • Author(s)
      Osada, S., Komatsu, M., Komatsu, F., Kagawa, Y.
    • Organizer
      38^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Bangkok, Thailand
    • Related Report
      2008 Final Research Report
  • [Presentation] Oxidative stress in long-bedridden patients who are nourishedwith intravenous high calorie alimentation (IVH) or tube feeding (TF).2006

    • Author(s)
      Komatsu, M., Osada, S., Komatsu, F., Kagawa, Y.
    • Organizer
      38^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Bangkok, Thailand
    • Related Report
      2008 Final Research Report
  • [Presentation] Mongolian people show high levels of reactive oxygen species in the blood compared to Japanese people2005

    • Author(s)
      Komatsu, F., Sakuma, M., Kawabata, T., Kaneko, Y., Kagawa, Y., Otgontuya, D., Ulziiburen Ch., Narantuya, L.
    • Organizer
      37^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2008 Final Research Report
  • [Presentation] Psychological aspects of Mongol inhabitants measured by GHQ-282005

    • Author(s)
      Sakuma, M., Komatsu, F., Kawabata, T., Kaneko, Y., Kagawa, Y., Otgontuya, D., Ulziiburen Ch., Narantuya, L.
    • Organizer
      37^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2008 Final Research Report
  • [Presentation] A survey on body composition and muscle power of the residents of Muren city, Mongolia2005

    • Author(s)
      Kaneko, Y., Komatsu, F., Sakuma, M., Kawabata, T., Kagawa, Y., Otgontuya, D., Ulziiburen Ch., Narantuya, L.
    • Organizer
      37^<th> Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2008 Final Research Report

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Published: 2005-04-01   Modified: 2016-04-21  

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