Deveopment of the ultrasound device to improve accuracy in the computer assisted surgery in total knee arthroplasty

• Project/Area Number: 17500328
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Medical systems
• Research Institution: Kobe University
• Principal Investigator: MURATSU Hirotsugu Kobe University, Graduate School of Medicine, Research fellow (30273783)
• Co-Investigator(Kenkyū-buntansha): NAGAMUNE Kouki Kobe University, Fukui Graduate School of Engineering, Lecturer (80397827) ; KURODA Ryosuke Kobe University Hospital, 医学部附属病院, Lecturer (80379362) ; YOSHIYA Shinichi Hyogo Medical College, 医学部, Professor (00201070) ; KURASAKA Masahiro Kobe University, Graduate School of Medicine, Professor (70170115) ; 水野 清典 神戸大学, 大学院医学系研究科, 特命講師 (40418778)
• Project Period (FY): 2005 – 2007
• Project Status: Completed (Fiscal Year 2007)
• Budget Amount: ¥3,850,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥150,000); Fiscal Year 2007: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2006: ¥100,000 (Direct Cost: ¥100,000); Fiscal Year 2005: ¥3,100,000 (Direct Cost: ¥3,100,000)
• Keywords: Information technoloey / Ultrasound / Electromagnetic sensor / Computer assisted suree / Knee / Knee arthroplasty / Clinical application / Orthopaedic surgery / コンピュータ支援技術

Research Abstract

1. Back ground & purpose: Computer assisted surgery has become popular in orthopedic surgery, and has been reported as an effective method to improve the accuracy in total knee arthroplasty. Nevertheless, manual determination of the anatomical reference point on the bone surface is potential source of error in the conventional system. In this research project, we developed new ultrasound system which could subjectively detect anatomical reference point and improve the accuracy in TKA navigation system.
2. Methods: We develope a new system, which integrates an ultrasound device and a 3D electromagnetic device. The ultrasound device is used for localizing the bone surface through the soft tissue. The 3D electromagnetic device is used for acquiring the 3D information of each points in real-time. One fresh-frozen human cadaveric knee was tested for the study. An identical examiner obtained anatomical reference points by a stylus with bone surface directly dissected, and obtained information of the bone surface by the developed new system. 6 degrees of freedom knee motion was measured by navigation system during passive knee motion. The kinematic data was compared between two different methods in obtaining anatomical reference pints.
3. Results: A proposed method could built the knee coordinate system which can be used as same as the conventional method. The error in motion data with the proposed method was within clinically acceptable range comparing to the result with direct dissection. This ultrasound device can be useful not only in total knee arthroplasty but also in total hip arthroplasty, spinal surgery and fracture fixation.

Research Products

• [Journal Article] ナビゲーションシステムを用いたTKA術中動作解析 (2008)
  • Author(s): 8. 村津裕嗣、久保晴司、木下恵祐、水野清典、黒田良祐、吉矢晋一、黒坂昌弘
  • Journal Title: 関節外科 27 Pages: 1232-1238
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] aIntra-operative 6 DOF knee kinematic analysis using TKA navigation system (2008)
  • Author(s): Muratsu, H, Kubo, S, Kinoshita, K, Mizuno, K, Kuroda, R, Yoshiya, S, Kurosaka, M
  • Journal Title: Joint Surgery 27(in press)
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Soft tissue balance measurement in anterior cruciate ligament-resected knee joint: cadaveric study as a model for cruciate-retaining total knee arthroplasty (2007)
  • Author(s): 5. Tanaka K, Muratsu H, Mizuno K, Kuroda R, Yoshiya S, Kurosaka M
  • Journal Title: J Orthop Sci 12 Pages: 149-153
  • NAID: 10019572458
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Influence of intra-operative joint gap on post-operative flexion angle in osteoarthritis patients undergoing posterior-stabilized total knee arthroplasty (2007)
  • Author(s): 6. Matsumoto T, Mizuno K, Muratsu H, Tsumura N, Fukase N, Kubo S, Yoshiya S, Kurosaka M, Kuroda R
  • Journal Title: Knee Surg Sports Traumatol Arthrosc 15 Pages: 1013-1018
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Soft tissue balance measurement in anterior cruciate ligament-resected knee joint: cadaveric study as a model for cruciate-retaining total knee arthroplasty (2007)
  • Author(s): Tanaka, K, Muratsu, H, Mizuno, K, Kuroda, R, Yoshiya, S, Kurosaka, M
  • Journal Title: J Orthop Sci 12 Pages: 149-153
  • NAID: 10019572458
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Influence of intra-operative joint gap on post-operative flexion angle in osteoarthritis patients undergoing posterior-stabilized total knee arthroplasty (2007)
  • Author(s): Matsumoto, T, Mizuno, K, Muratsu, H, Tsumura, N, Fukase, N, Kubo, S, Yoshiya, S, Kurosaka, M, Kuroda, R
  • Journal Title: Knee Surg Sports Traumatol Arthrosc 15 Pages: 1013-1018
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Joint gap kinematics in posterior-stabilized total knee arthroplasty measured by a new tensor with the navigation system (2006)
  • Author(s): 3. Matsumoto T, Muratsu H, Tsumura N, Mizuno K, Kuroda R, Yoshiya S, Kurosaka M
  • Journal Title: J Biomech Eng 128 Pages: 867-871
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Determination Method of the Femoral Bone Coordinate System by Integrating Ultrasound Device with 3D Electromagnetic Device (2006)
  • Author(s): 4. Nagamune K, Muratsu H, Nishimoto K, Hoshino Y, Tanaka K, Mizuno K, Yagi Y, Kuroda R, Yoshiya R, Kurosaka M
  • Journal Title: SCIS&ISIS2006 Pages: 1842-1847
  • NAID: 130004672446
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Joint gap kinematics in posterior-stabilized total knee arthroplasty measured by a new tensor with the navigation systm (2006)
  • Author(s): Matsumoto, T, Muratsu, H, Tsumura, N, Mizuno, K, Kuroda, R, Yoshiya, S, Kurosaka, M
  • Journal Title: J Biomech Eng 128 Pages: 867-871
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Determination Method of the Femoral Bone Coordinate System by Integrating Ultrasound Device with 3D Electromagnetic Device (2006)
  • Author(s): Nagamune, K, Muratsu, H, Nishimoto, K, Hoshino, Y, Tanaka, K, Mizuno, K Yagi, Y, Kuroda, R, Yoshiya, R, Kurosaka, M
  • Journal Title: SCIS&ISIS2006 Pages: 1842-1847
  • NAID: 130004672446
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Joint surface geometry based standardization for the ACL insertion by using fuzzy logic (2005)
  • Author(s): 1. Nagamune K, Muratsu H, Hoshino Y, Tanaka K, Mizuno K, Kuroda R, Kurosaka M, Yagi M, Yoshiya S
  • Journal Title: Proceeding of the 2005 IEEE International Conference on Systems Pages: 1949-1954
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Non-invasive real time visualization of the 6 DOF knee kinematics during manual testing (2005)
  • Author(s): 2. Nagamune K, Muratsu H, Hoshino Y, Tanaka K, Kubo S, Yagi M, Mizuno K, Kuroda R, Yoshiya S, Kurosaka M
  • Journal Title: Proceeding of Orthopaedic Research Society,
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] 人工膝関節手術におけるナビゲーションシステムの注意点と今後の展望 (2005)
  • Author(s): 7. 長宗高樹、田中浩一、村津裕嗣、吉矢晋一、黒坂昌弘
  • Journal Title: 関節外科 24 Pages: 107-112
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Joint surface geometry based standardization for the ACL insertion by using fuzzy logic (2005)
  • Author(s): Nagamune, K, Muratsu, H, Hoshino, Y, Tanaka, K, Mizuno, K, Kuroda, R, Kurosaka, M, Yagi, M, Yoshiya, S
  • Journal Title: Proceeding of the 2005 IEEE International Conference on Systems Pages: 1949-1954
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Non-invasive real time visualization of the 6 DOF knee kinematics during manual testing (2005)
  • Author(s): Nagamune, K, Muratsu, H, Hoshino, Y, Tanaka, K, Kubo, S, Yagi, M, Mizuno, K, Kuroda, R, Yoshiya, S, Kurosaka, M
  • Journal Title: Proceeding of Orthopaedic Research Society
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Point of issue in the TKA navigation system (2005)
  • Author(s): Nagamune, K, Tanaka, K, Muratsu, H, Yoshiya, S, Kurosaka, M
  • Journal Title: Joint Surgery 24 Pages: 107-112
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 人工膝関節置換術における超音波装置を用いたナビゲーションシステムの開発 (2007)
  • Author(s): 9 村津裕嗣、長宗 高樹、久保晴司、水野清典、黒田良祐、吉矢晋一、黒坂昌弘
  • Organizer: 第34回 日本臨床バイオメカニクス学会
  • Place of Presentation: 東京
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Development of TKA navigation system using ultrasound (2007)
  • Author(s): Muratsu, H, Nagamune, K, Kubo, S, Mizuno, K, Kuroda, R, Yoshiya, S, Kurosaka, M
  • Organizer: 34th. Japanese Society of Clinical Biomechanics
  • Place of Presentation: Tokyo
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] 人工膝関節置換術における超音波装置を用いたビゲーションシステムの開発 (2007)
  • Author(s): 村津 裕嗣
  • Organizer: 第34回日本臨床バイオメカ学会
  • Place of Presentation: 東京
• [Presentation] Difference in knee flexion angle during arthroscopic ACL reconstruction may affect the accuracy of femoral tunnel placement (2006)
  • Author(s): 2. Nagamune K, Muratsu H, Nishimoto K, Hoshino Y, Tanaka K, Mizuno K, Yagi M, Kuroda R, Yoshiya S, Kurosaka M
  • Organizer: 12th. ESSKA
  • Place of Presentation: Innsbruck
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Determination Method of the Femoral Bone Coordinate System by Integrating Ultrasound Device with 3D EIectromagnetic Device (2006)
  • Author(s): 3 Nagamune K, Muratsu H, Nishimoto K, Hoshino Y, Tanaka K, Mizuno K, Yagi Y, Kuroda R, Yoshiya R, Kurosaka M
  • Organizer: SCIS&ISIS2006
  • Place of Presentation: Tokyo
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 3次元膝運動解析の有用性(新たな人工膝関節デザインの膝運動解析) (2006)
  • Author(s): 8 村津裕嗣、柴沼均、山口基、水野清典、小橋昌司、近藤克哉、吉矢晋一、畑豊、黒坂昌弘
  • Organizer: 第33回日本臨床バイオメカニクス学会
  • Place of Presentation: 新潟
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Determination Method of the Femoral Bone Coordinate System by Integrating Ultrasound Device with 3D Electromaenetic Device (2006)
  • Author(s): Nagamune, K, Muratsu, H, Nishimoto, K, Hoshino, Y, Tanaka, K, Mizuno, K, Yagi, Y, Kuroda, R, Yoshiya, R, Kurosaka, M
  • Organizer: SCIS&ISIS
  • Place of Presentation: Tokyo
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Usefulness' of 3D knee kinematic Analysis for the evaluation of newly developed TKA (2006)
  • Author(s): Muratsu, H, Shibanuma, N, Yamaguchi, M, Mizuno, K, Kobashi, M, Kondo, K, Yoshiya, S, Hata, Y, Kurosaka, M
  • Organizer: 33rd Japanese Society of Clinical Biomechanics
  • Place of Presentation: Niigata
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Intra-operative 6 DOF motion measurements using a newly developed TKA navigation system (2005)
  • Author(s): 1. Muratsu H, Kurosaka M
  • Organizer: Expertise in Orthopaedic Navigation System
  • Place of Presentation: Edinburgh
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 新たな膝前十字靭帯付着位置の標準化の試み (2005)
  • Author(s): 4 村津裕嗣、長宗高樹、星野祐一、田中浩一、木下恵祐、水野清典、八木正義、黒田良祐、吉矢晋一、黒坂昌弘
  • Organizer: 第31回日本整形外科スポーツ学会
  • Place of Presentation: 奈良
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] ナビゲーションシステムを用いたTKA術中3次元動作解析の試み (2005)
  • Author(s): 5 水野清典、村津裕嗣、長宗高樹、田中浩一、星野祐一、高倉義幸、松本彰生、黒田良祐、吉矢晋一、黒坂昌弘
  • Organizer: 第78回日本整形外科学会学術集会
  • Place of Presentation: 横浜
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] 解剖学的2重束ACL再建術で移植腱固定部位決定を支援するナビゲーションシステムの開発 (2005)
  • Author(s): 6 村津裕嗣、長宗高樹、八木正義、黒田良祐、吉矢晋一、黒坂昌弘
  • Organizer: 第20回日本整形外科基礎学術集会
  • Place of Presentation: 伊勢市
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Pivot shift testにおける膝運動の非侵襲的計測 (2005)
  • Author(s): 7 星野祐一、村津裕嗣、長宗高樹、田中浩一、八木正義、水野清典、黒田良祐、山口基、黒坂昌弘
  • Organizer: 第32回日本臨床バイオメカニクス学会
  • Place of Presentation: 札幌
  • Description: 「研究成果報告書概要(和文)」より
• [Presentation] Standardizing methods for the ACL insertion sites (2005)
  • Author(s): Muratsu, H, Nagamune, K, Hoshino, S, Tanaka, K, Kinoshita, K, Mizuno, K, Yagi, M, Kuroda, R, Yoshiya, S, Kurosaka, M
  • Organizer: 31th Japan Orthopaedic Sports Medicine
  • Place of Presentation: Nara
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Intra-operative knee Kinematic analysis using TKA navigation system (2005)
  • Author(s): Mizuno, K, Muratsu, H, Nagamune, K, Tanaka, K, Hoshino, Y, Takakura, Y Matsumoto, A, Kuroda, R, Yoshiya, S, Kurosaka, M
  • Organizer: 78th, Japan Orthopaedic Association
  • Place of Presentation: Yokohama
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] New navigation system assisting fixation site determination in the anatomical two bundle ACL recnnstrurtinn (2005)
  • Author(s): Muratsu, H, Nagamune, K, Yagi, M, Kuroda, R, Yoshiya, S, Kurosaka, M
  • Organizer: 20th. Japan Orthopaedic Research Society
  • Place of Presentation: Mie
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Non-invasive measurement of knee kinematics during- nivnt shiff tact (2005)
  • Author(s): Hoshino, S, Muratsu, H, Nagamune, K, Tanaka, K, Yagi, M, Mizuno, K, Kuroda, R, Yamaguchi, M, Kurosaka, M
  • Organizer: 32nd. Japanese Society of Clinical Biomechanics
  • Place of Presentation: Sapporo
  • Description: 「研究成果報告書概要(欧文)」より