| Project/Area Number |
17560241
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
TANAKA Yoshio National Institute of Advanced Industrial Science and Technology, AIST, Health Technology Research Center, Senior Research Scintist (30357454)
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| Co-Investigator(Kenkyū-buntansha) |
HIRANO Ken AIST, Research Scintist (80392653)
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| Project Period (FY) |
2005 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥3,540,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2006: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2005: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Keywords | Optical Tweezers / Micro Manipulation / Image Processing / ナノバイオ / マイクロ・ナノデバイス |
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| Research Abstract |
Laser manipulation is an important technique suitable for controlling/handling fluid-borne objects at length scales ranging from sub-micrometers to micrometers in a closed space such as Lab-on-a-Chip. However, almost all previous works have been limited to two-dimensional(2D) space or spherical objects such as beads, droplets and others. Furthermore, the control system and user-interfaces of conventional optical tweezers system is insufficient to manipulate objects in 3D working space, if the intention is to manipulate dexterously or automatically the objects in real time. The manipulation of arbitrarily shaped objects in 3D space is essential and of widespread importance, since many naturally occurring objects as well as microfabricated objects are not spherical. Automatic manipulation based on image processing techniques will be also important for Lab-on-a-Chips.
In our project, we have developed a personal computer(PC) controlled 3D laser trapping-ablation system combined with real-t
… More
ime image processing techniques and mouse-controlled user-interfaces and have carried out several demonstrations using samples with various optical properties and shapes. We have also proposed a new non-contact 3D manipulation technique based on 'optical lever effect' for non-spherical micro-objects. The three-beam optical tweezers, the line-scanning laser trap and the optical-lever manipulation using our system have enabled real-time orientation control in 3D space. Tilt angle control translation and rotation of the non-spherical micro objects were demonstrated by various manipulation schemes. Although we have dealt only with a few samples with non-spherical shape, these results, we believe, could open up new possibilities for positioning and orienting arbitrarily shaped objects in 3D space using laser trapping. Furthermore, it is expected that the manipulation schemes coupled with computer vision techniques will perform fully-automated dexterous manipulations of non-spherical objects in various research fields as well as MEMS and Lab-on-a-Chip. Less
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