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Pelvic Organ Prolapse and Sagging of the Levator Plate : A Study Using Functional Cine-MRI

Research Project

Project/Area Number 17591688
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionFukuhisma Medical University

Principal Investigator

YOSHIMURA Yasukuni  Fukuhisma Medical University, School of Medicine, postdoctoral fellow (50220744)

Co-Investigator(Kenkyū-buntansha) AIKAWA Ken  公立大学法人福島県立医科大学, 医学部, research assistant (80295419)
Project Period (FY) 2005 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,450,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥150,000)
Fiscal Year 2007: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2006: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2005: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsPelvic Floor Muscle / Pelvic Organ Prolapse / cine MRI / Levator Muscle / Levator Plate / Pelvic Floor function / 機能解部学 / 機能解剖学
Research Abstract

Background : It is generally accepted that the sagging of levator plate (LP) leads to progressive widening of the urogenital hiatus and the development of pelvic organ prolapse (POP). This study attempts to find the relationship between the sagging of LP and POP.
Methods : We retrospectively evaluated the functional cine-MRI studies of 63 symptomatic POP patients (mean age 62.4y) and 7 females with normal pelvic support (mean age 42.3y). All subjects underwent MR imaging of the pelvis in the supine position at rest and at straining (Valsalva maneuver) in the evening at aroud the time of 5 pm. The angle between the pubococcygeal line (PCL) and levator plate was calculated (sagging angle, SA). Results : The values of SA were +35.31±11.2 deg. in POP group and -8.9±10.6 deg. in control group, respectively (p<0.01). Among 63 POP patients, 44 (69.8%) has larger SA (more than 30 deg. mean 41.3 deg.) and 19 (30.2%) has small SA (less than 30 deg. mean 21.6 deg.).
Conclusion : Patients with POP had significantly greater SA than control female. However, about 30% of POP patients do not have overt LP sagging. This may suggest the mode of the development of POP is varied.

Report

(4 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (10 results)

All 2010 2009 2008 2007

All Journal Article (3 results) Presentation (6 results) Book (1 results)

  • [Journal Article] 骨盤臓器脱症例における,肛門挙筋板のたわみに関するcine MRIを用いた検討2010

    • Author(s)
      嘉村康邦
    • Journal Title

      日本女性骨盤底医学会誌 7(印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Pelvic Organ Prolapse and Sagging of the Levator Plate : A Study Using Functional Cine-MRI(in Japanese)2010

    • Author(s)
      Y.Yoshimura
    • Journal Title

      Journal of Japan Female Pelvic Floor Medicine Vol.7(in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Evaluation of the Dynamic Responses of Female Pelvic Floor Using a Novel Vaginal Probe2007

    • Author(s)
      CHRIS E.CONSTANTINOU, SADAO OMATA, YASUKUNI YOSHIMURA, QIYU PENG
    • Journal Title

      Ann.N.Y.Acad.Sci 21101:

      Pages: 297-315

    • Related Report
      2006 Annual Research Report
  • [Presentation] Pelvic Organ Prolapse and Sagging of the Levator Plate : A Study Using Functional Cine-MRI2009

    • Author(s)
      Y.Yoshimura
    • Organizer
      11^<th> annual meeting of Australian Association of Vaginal Incontinence Surgeons
    • Place of Presentation
      Noosa, オーストラリア
    • Year and Date
      2009-07-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Pelvic Organ Prolapse and Sagging of the Levator Plate : A Study Using Functional Cine-MRI2009

    • Author(s)
      Y.Yoshimura
    • Organizer
      11^<th> annual meeting of Australian Association of Vaginal Incontinence Surgeons
    • Place of Presentation
      Australia
    • Year and Date
      2009-07-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 骨盤臓器脱症例における,肛門挙筋板のたわみに関するcine MRIを用いた検討2009

    • Author(s)
      嘉村康邦
    • Organizer
      第11回日本女性骨盤底医学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-07-04
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Pelvic Organ Prolapse and Sagging of the Levator Plate : A Study Using Functional Cine-MRI2009

    • Author(s)
      Y.Yoshimura
    • Organizer
      11^<th> The Japanese Society of Female Pelvic Floor Medicine
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2009-07-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] The Degree of Uterine Prolapse Determines the Severity of Cystocele in Patient with POP~A Study Using Functional Cine-MRI~2008

    • Author(s)
      Y.Yoshimura
    • Organizer
      10^<th> annual meeting of Australian Association of Vaginal Incontinence Surgeons
    • Place of Presentation
      Padua Veniceイタリア
    • Year and Date
      2008-10-02
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] The Degree of Uterine Prolapse Determines the Severity of Cystocele in Patient with POP~A Study Using Functional Cine-MRI~2008

    • Author(s)
      Y.Yoshimura
    • Organizer
      10^<th> annual meeting of Australian Association of Vaginal Incontinence Surgeons
    • Place of Presentation
      Venice, Italy
    • Year and Date
      2008-10-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] Audio-Visual Journal of JUA骨盤増遺脱の診断・手術特集『骨盤臓器脱の診断』2009

    • Author(s)
      嘉村康邦
    • Publisher
      (株)インターメディカ
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary

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Published: 2005-04-01   Modified: 2016-04-21  

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