|Budget Amount *help
¥43,160,000 (Direct Cost: ¥33,200,000、Indirect Cost: ¥9,960,000)
Fiscal Year 2020: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2019: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2018: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2017: ¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
|Outline of Final Research Achievements
Only a small fraction of the sequence space has been explored by nature through evolution. By rational design, it is now clear that for soluble proteins, there are many artificial proteins that possess structures and functions in the unexplored sequence space. In this study, we show that there are molecules with artificial membrane proteins that also have functions and structures in membrane proteins. Specifically, we designed an artificial membrane protein with a 2 nm pore and clarified its function using an artificial cell reactor.