• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Beneficial association of spirituality/religiosity on psychological and physical health via allostatic adaptation.

Research Project

Project/Area Number 17H02171
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionFoundation for Advancement of International Science

Principal Investigator

Murakami Kazuo  公益財団法人国際科学振興財団, バイオ研究所, 主席研究員 (70110517)

Co-Investigator(Kenkyū-buntansha) 堀 美代  公益財団法人国際科学振興財団, その他部局等, 専任研究員 (90399329)
坂本 成子  公益財団法人国際科学振興財団, その他部局等, 専任研究員 (60419869)
大西 淳之  東京家政大学, 家政学部, 教授 (40261276)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2019: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2018: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2017: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Keywords遺伝子発現 / メタボローム解析 / アロスタシス / 瞑想 / 祈り / ヨーガ / 心身技法 / 宗教性 / 分子マーカー / メタボローム / マイクロアレイ解析 / 共感性
Outline of Final Research Achievements

Our purpose in this study is to explore the role of spiritual/religious involvement across the biological markers, including transcripts and metabolites, associated with psychological aspects of Buddhist priests and YOGA practitioners. We identified distinguishing biological alterations in Buddhist priests and non-priest controls during GOMA ritual involvement. The identified biological characters include genes associated with inflammation, fatty acid metabolism, and NK cell regulation. Next, we examined transcriptional and metabolic changes YOGA practice in YOGA practitioners and non-experience controls. Both groups showed specific changes in metabolites related to the biosynthesis and degradation of ketone bodies in practice. Interestingly, we uncovered that long term YOGA practitioners exhibited distinct patterns of transcripts and metabolites comparing with controls in the basal state, indicating that these observations may be long-lasting changes as allostatic responses to YOGA.

Academic Significance and Societal Importance of the Research Achievements

祈りや瞑想などの宗教性を含む心身技法を実施することにより、アロスタシス変容を引き起こす可能性を見出すことができた。このことは個人のアロスタシスによるストレス対処力を強化する点でも意義がある。また、その効果は習慣的に長期間実施することによって、より有効に作用する可能性が示唆された。
瞑想や祈りなどの宗教性は、人類の営みの中で、我々の生き方や社会性の基盤となり、何千年もの間育まれ続けてきた。本研究成果は、その普遍性対する科学的根拠のひとつになりうると思われる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (15 results)

All 2019 2017 Other

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (2 results) (of which Int'l Joint Research: 1 results) Book (1 results) Remarks (7 results)

  • [Journal Article] Renin-angiotensin system research: from molecules to the whole body2019

    • Author(s)
      Eriko Takimoto-Ohnishi and Kazuo Murakami
    • Journal Title

      The Journal of Physiological Sciences

      Volume: 69(4) Issue: 4 Pages: 581-587

    • DOI

      10.1007/s12576-019-00679-4

    • NAID

      40021916333

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distinct Transcriptional and Metabolic Profiles Associated with Empathy in Buddhist Priests: A Pilot Study2017

    • Author(s)
      Ohnishi J, Ayuzawa S, Nakamura S, Sakamoto S, Hori M, Sasaoka T, Takimoto-Ohnishi E, Tanatsugu M, Murakami K.
    • Journal Title

      Human Genomics

      Volume: 11 Issue: 1 Pages: 3-16

    • DOI

      10.1186/s40246-017-0117-3

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 病気を笑いで癒やす2017

    • Author(s)
      堀美代,村上和雄
    • Journal Title

      体育の科学

      Volume: 67 Pages: 551-554

    • Related Report
      2017 Annual Research Report
  • [Journal Article] いのちと遺伝子2017

    • Author(s)
      村上和雄
    • Journal Title

      高野山大学 密教文化研究所紀要

      Volume: 別冊 Pages: 7-9

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 祈りや宗教性が遺伝子発現に与える影響―真言宗僧侶における研究2017

    • Author(s)
      鮎澤聡,坂本成子,堀美代,笹岡知子,大西英里子,中村本然,棚次正和,大西淳之,村上和雄
    • Journal Title

      高野山大学 密教文化研究所紀要

      Volume: 別冊 Pages: 9-18

    • Related Report
      2017 Annual Research Report
  • [Presentation] Dopamine D1 and D2/3 receptor antagonism effect on tickling induced 50-kHz ultrasonic vocalizations in the adolescent rats2017

    • Author(s)
      Hori M, Shimoju R, Ohnishi J, Murakami K, Kurosawa M.
    • Organizer
      SOCIETY FOR NEUROSCIENCE 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Gene expression profiling: effects of tickling on restraint stress in the adolescent rats.2017

    • Author(s)
      Hori M, Ohnishi J, Yamada K, Sakamoto S, Ichitani Y, Murakami K.
    • Organizer
      行動2017
    • Related Report
      2017 Annual Research Report
  • [Book] 君のやる気スイッチをオンにする遺伝子の話 (鹿児島の高校生たちが感動した命の授業)2017

    • Author(s)
      村上和雄
    • Total Pages
      137
    • Publisher
      致知出版社
    • ISBN
      9784800911520
    • Related Report
      2017 Annual Research Report
  • [Remarks] 心と遺伝子研究会

    • URL

      http://mind-gene.com/

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
  • [Remarks] 村上和雄 心と遺伝子研究会

    • URL

      https://www.facebook.com/mindgene.murakami

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
  • [Remarks] 【祈りは遺伝子を「活性化」する】産経新聞「正論」1月11日に掲載されました

    • URL

      http://mind-gene.com/blog/news/1167/

    • Related Report
      2017 Annual Research Report
  • [Remarks] 祈りは遺伝子を活性化する ~論文第一報~

    • URL

      http://mind-gene.com/blog/news/1156/

    • Related Report
      2017 Annual Research Report
  • [Remarks] Neuroscience 2017

    • URL

      http://mind-gene.com/blog/news/1149/

    • Related Report
      2017 Annual Research Report
  • [Remarks] 祈りは遺伝子を「活性化」する「産経新聞【正論】2018年1月11日

    • URL

      https://www.facebook.com/mindgene.murakami/?hc_ref=ARR8fedJIOIMgBg-JiH9PESyPRWUGjRiUKyJfOCrsDSjzqtV9Eo8Vm3Vu47uibfH-lA&fref=nf

    • Related Report
      2017 Annual Research Report
  • [Remarks] 祈りは遺伝子を活性化する ~論文第一報~

    • URL

      https://www.facebook.com/mindgene.murakami/?hc_ref=ARR8fedJIOIMgBg-JiH9PESyPRWUGjRiUKyJfOCrsDSjzqtV9Eo8Vm3Vu47uibfH-lA&fref=nf

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2021-02-19  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi