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Experimental and numerical studies on the Segre-Silberberg effect

Research Project

Project/Area Number 17H03176
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Fluid engineering
Research InstitutionKansai University

Principal Investigator

Sugihara-Seki Masako  関西大学, システム理工学部, 教授 (80150225)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2019: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2017: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
KeywordsSegre-Silberberg効果 / 混相流 / 管内流れ / 慣性 / 平衡位置 / 揚力 / 流体 / 粒子 / 粘弾性
Outline of Final Research Achievements

The inertial migration and focusing of particles suspended in a pressure-driven flow through straight tubes with various cross-sections and various sizes was investigated experimentally and numerically in a wide range of Reynolds numbers. In experiments, direct observations of the particle distribution in downstream cross-sections indicated the presence of several types of the particle focusing position in the tube cross-section and several regimes of the Reynolds number for the particle focusing pattern, depending on the size ratio of the particle diameter to the tube width, rheological properties of the particle and the suspending medium as well as the cross-sectional shape of the tube. The numerical simulation using the immersed boundary method accounted for the particle focusing patterns observed experimentally, and provided the explanation for the transition between the particle focusing patterns, based on the lateral force exerted on the particle.

Academic Significance and Societal Importance of the Research Achievements

流路内層流に浮遊する粒子が慣性に起因する揚力を受け,粒子の大きさや物性等に応じて流路下流の断面内で特定の位置に集中する現象は Segre-Silberberg効果と呼ばれ,粒子の分離・精製への応用が期待されている.本研究は,様々な条件における流路断面内の粒子の集中位置と集中パターンを詳しく調べた研究であり,流速,流路断面形状,粒子の大きさや物性,媒質の物性に依存した粒子集中現象が明らかとなり,浮遊粒子の分別や分離へ応用するための基礎データが示された.

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (46 results)

All 2020 2019 2018 2017 Other

All Int'l Joint Research (1 results) Journal Article (8 results) (of which Peer Reviewed: 8 results,  Open Access: 1 results) Presentation (35 results) (of which Int'l Joint Research: 11 results,  Invited: 3 results) Remarks (2 results)

  • [Int'l Joint Research] Aston University(英国)

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Three regimes of inertial focusing for spherical particles suspended in circular tube flows2019

    • Author(s)
      Nakayama Saki、Yamashita Hiroshi、Yabu Takuya、Itano Tomoaki、Sugihara-Seki Masako
    • Journal Title

      Journal of Fluid Mechanics

      Volume: 871 Pages: 952-969

    • DOI

      10.1017/jfm.2019.325

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Estimating timescale of unstirred layer formation in osmotically driven flow2019

    • Author(s)
      Itano Tomoaki、Konno Keito、Inagaki Taishi、Sugihara-Seki Masako
    • Journal Title

      Journal of Physics Communications

      Volume: 3 Issue: 1 Pages: 015007-015007

    • DOI

      10.1088/2399-6528/aafc09

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Bifurcation phenomena on the inertial focusing of a neutrally buoyant spherical particle suspended in square duct flows2019

    • Author(s)
      Yamashita Hiroshi、Itano Tomoaki、Sugihara-Seki Masako
    • Journal Title

      Physical Review Fluids

      Volume: 4 Issue: 12 Pages: 124307-124307

    • DOI

      10.1103/physrevfluids.4.124307

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Numerical study on the axisymmetric state in sphericalCouette flow under unstable thermal stratification2019

    • Author(s)
      Taishi Inagaki, Tomoaki Itano, Masako Sugihara-Seki
    • Journal Title

      Acta Mechanica

      Volume: 230 Issue: 10 Pages: 3499-3509

    • DOI

      10.1007/s00707-019-02487-8

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three regimes of inertial focusing for spherical particles suspended in circular tube flows2019

    • Author(s)
      Saki Nakayama, Hiroshi Yamashita, Takuya Yabu, Tomoaki Itano and Masako Sugihara-Seki
    • Journal Title

      Journal of Fluid Mechanics

      Volume: 印刷中

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cross-sectional distributions of normal and abnormal red blood cells in capillary tubes determined by a new technique.2018

    • Author(s)
      Sasaki, T., Seki, J., Itano, T., Sugihara-Seki, M.
    • Journal Title

      Biorheology

      Volume: 印刷中 Issue: 5-6 Pages: 153-165

    • DOI

      10.3233/bir-18166

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Experimental and numerical study on the inertial focusing of spherical particles suspended in square channel flows2018

    • Author(s)
      Masako Sugihara-Seki and Hiroshi Yamashita
    • Journal Title

      Proceedings of Conference on Modelling Fluid Flow (CMFF'18)

      Volume: - Pages: 108-108

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inertial migration regimes of spherical particles suspended in square tube flows.2017

    • Author(s)
      Shichi, H., Yamashita, H., Seki, J., Itano, T. and Sugihara-Seki, M.
    • Journal Title

      Physical Review Fluids

      Volume: 2 Issue: 4 Pages: 044201-044201

    • DOI

      10.1103/physrevfluids.2.044201

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] 正常赤血球および硬化赤血球の原子間力顕微鏡による膜弾性計測2020

    • Author(s)
      小野澤天紀、瀧ノ内希陸、仲尾信彦、安達泰治、関 眞佐子
    • Organizer
      第24回関西大学先端科学技術シンポジウム
    • Related Report
      2019 Annual Research Report
  • [Presentation] 微小矩形管内流れ中の赤血球の断面内分布2020

    • Author(s)
      田中沙織,板野智昭,関眞佐子
    • Organizer
      日本物理学会 第75回年次大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Y字型分岐流路における血小板模擬粒子の断面内分布の進展2019

    • Author(s)
      小野澤天紀,板野智昭,関眞佐子
    • Organizer
      日本バイオレオロジー学会第42回年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 粘弾性流体の正方形管内層流に浮遊する球形粒子の管断面内分布2019

    • Author(s)
      三木祐太,山下博士,板野智昭,関眞佐子
    • Organizer
      混相流シンポジウム2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] 粒子サスペンションの円管内層流で見られるSegre-Silberberg 効果2019

    • Author(s)
      山下博士,板野智昭,関眞佐子
    • Organizer
      日本物理学会秋季大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 赤血球サスペンション流れに浮遊する血小板模擬粒子のマージネーション2019

    • Author(s)
      関眞佐子,小野澤天紀
    • Organizer
      日本流体力学会年会2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] Lateral migration of particles and blood cells suspended in tube flows2019

    • Author(s)
      Masako Sugihara-Seki
    • Organizer
      Mathematical Methods in Biofluid Mechanics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of margination of platelet-sized particles suspended in red cell suspension flows through Y-shaped bifurcating microchannels2019

    • Author(s)
      Tenki Onozawa, Toma Kawauchi, Junji Seki, Tomoaki Itano, Masako Sugihara-Seki
    • Organizer
      72nd Annual Meeting of the APS Division of Fluid Dynamics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Aerodynamic characteristics and flight behavior of the turbo-jav in the javelic throw2019

    • Author(s)
      Haruki Nakayama, Tomoya Nakajima, Tomoaki Itano, Masako Sugihara-Seki
    • Organizer
      72nd Annual Meeting of the APS Division of Fluid Dynamics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 矩形管内非ニュートン流体中の慣性粒子の軌道2019

    • Author(s)
      横山直人、山下博士、板野智昭、関眞佐子
    • Organizer
      第23回関西大学先端科学技術シンポジウム講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 正方形ダクト内サスペンション流れ中の粒子集中パターンの変化2019

    • Author(s)
      山下博、横山直人、板野智昭、関眞佐子
    • Organizer
      日本物理学会第74回年次大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] マイクロチャネル内血液流れ中の血小板模擬粒子の分布2018

    • Author(s)
      瀧ノ内希陸、小野澤天紀、関淳二、板野智昭、関眞佐子
    • Organizer
      第41回日本バイオレオロジー年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 硬化及び軟化赤血球サスペンション流れ中の血小板模擬粒子の流路内分布2018

    • Author(s)
      小野澤天紀、瀧ノ内希陸、福本翼、関淳二、板野智昭、関眞佐子
    • Organizer
      第41回日本バイオレオロジー年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Fluid dynamical study of preferential distributions of blood cell components in microchannel flows2018

    • Author(s)
      Masako Sugihara-Seki, Nozomi Takinouchi, Tenki Onozawa, Junji Seki
    • Organizer
      Joint Meeting of ESCHM-ISB-ISCH
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] サブミリ円管内層流に浮遊する球形粒子の断面分布2018

    • Author(s)
      中山紗季、山下博士、板野智昭、関眞佐子
    • Organizer
      混相流シンポジウム2018
    • Related Report
      2018 Annual Research Report
  • [Presentation] 正方形ダクト内希薄サスペンション流れにおける球形粒子の慣性集中現象2018

    • Author(s)
      山下博士、宗圓龍星、横山直人、板野智昭、関眞佐子
    • Organizer
      日本物理学会2018年秋季大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Experimental and numerical study on the inertial focusing of spherical particles suspended in square channel flows2018

    • Author(s)
      Masako Sugihara-Seki and Hiroshi Yamashita
    • Organizer
      Conference on Modelling Fluid Flow (CMFF'18)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 微小管内を流れる赤血球の断面内分布2018

    • Author(s)
      住田聡之、後藤隆志、関淳二、板野智昭、関眞佐子
    • Organizer
      第66回レオロジー討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 正方形ダクト内層流に浮遊する球形粒子の断面内集中現象2018

    • Author(s)
      山下博士、宗圓龍星、横山直人、板野智昭、関眞佐子
    • Organizer
      第66回レオロジー討論会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Inertial focusing of spherical particles suspended in laminar circular tube flows2018

    • Author(s)
      Saki Nakayama, Hiroshi Yamashita, Tomoaki Itano, Masako Sugihara-Seki
    • Organizer
      71st Annual Meeting of the APS Division of Fluid Dynamics
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Margination of platelet-sized particles in normal and hardened red blood cell suspension flows2018

    • Author(s)
      Nozomi Takinouchi, Tenki Onozawa, Junji Seki, Tomoaki Itano, Masako Sugihara-Seki
    • Organizer
      71st Annual Meeting of the APS Division of Fluid Dynamics
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Inertial focusing phenomena of neutrally buoyant particles suspended dilutely in square duct flows2018

    • Author(s)
      Hiroshi Yamashita, Ryusei Soen, Naoto Yokoyama, Tomoaki Itano, Masako Sugihara-Seki
    • Organizer
      71st Annual Meeting of the APS Division of Fluid Dynamics
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 流路内の球状粒子集中現象の数値解析2018

    • Author(s)
      牧野真人,関眞佐子
    • Organizer
      第22回関西大学先端科学技術シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] 界面活性剤水溶液の正方形管内流れにおける浮遊粒子の分布2018

    • Author(s)
      中川湧斗,久保あいり,中山紗希,山下博士,板野智昭,関眞佐子
    • Organizer
      日本物理学会第73回年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 赤血球サスペンションの微小流路流れにおける血小板模擬粒子の断面内分布2017

    • Author(s)
      瀧ノ内希陸, 佐々木崇洋, 関淳二, 板野智昭, 関眞佐子
    • Organizer
      第40回日本バイオレオロジー学会年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 赤血球軸集中現象の顕微計測-変形性の影響2017

    • Author(s)
      佐々木崇洋, 関淳二,板野智昭,関眞佐子
    • Organizer
      第40回日本バイオレオロジー学会年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 矩形ダクト内流れにおける単一球形粒子の断面内集中現象2017

    • Author(s)
      山下博士,板野智昭,関眞佐子
    • Organizer
      日本混相流学会混相流シンポジウム2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] 微小円管内層流に浮遊する球形粒子分布の計測2017

    • Author(s)
      中山紗希,山下博士,板野智昭,関淳二,関眞佐子
    • Organizer
      日本流体力学会年会2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] 赤血球の軸集中現象に及ぼす変形性の影響2017

    • Author(s)
      佐々木崇洋,関淳二,板野智昭,関眞佐子
    • Organizer
      日本流体力学会年会2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] 血液流れ中の血小板のマージネーション2017

    • Author(s)
      関眞佐子
    • Organizer
      「生物機械システム研究会」第47回研究会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Focusing Regimes in Laminar Suspension Flows through Square Ducts2017

    • Author(s)
      Yamashita, H., Itano, T., Sugihara-Seki, M.
    • Organizer
      14th International Conference on Flow Dynamics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Inertial Particle Focusing Regimes in Suspension Flows through Square Ducts2017

    • Author(s)
      Yamashita, H., Itano, T., Sugihara-Seki,M.
    • Organizer
      70th Annual Meeting of the APS Division of Fluid Dynamics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Microscopic Measurements of Axial Accumulation of Red Blood Cells in Capillary Flows -Effects of Deformability-2017

    • Author(s)
      Sasaki, T., Seki, J., Itano, T., Sugihara-Seki, M.
    • Organizer
      70th Annual Meeting of the APS Division of Fluid Dynamics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] マイクロチャネル内血液流れ中の血小板模擬粒子の分布2017

    • Author(s)
      瀧ノ内希陸,佐々木崇洋,関淳二,板野智昭,関眞佐子
    • Organizer
      日本機械学会第30回バイオエンジニアリング講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 硬化赤血球サスペンション流れにおける血小板模擬粒子の断面内分布2017

    • Author(s)
      小野澤天紀,瀧ノ内希陸,佐々木崇洋,関淳二,板野智昭,関眞佐子
    • Organizer
      日本機械学会第30回バイオエンジニアリング講演会
    • Related Report
      2017 Annual Research Report
  • [Remarks] 関西大学学術情報システム

    • URL

      http://gakujo.kansai-u.ac.jp/search/index.jsp

    • Related Report
      2019 Annual Research Report 2017 Annual Research Report
  • [Remarks] 関西大学学術リポジトリ

    • URL

      https://kuir.jm.kansai-u.ac.jp/dspace/

    • Related Report
      2018 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2021-02-19  

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