| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2020: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2019: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2018: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2017: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Outline of Final Research Achievements |
If a three-dimensional fabrication method with high biocompatibility in a micro-enclosed space is developed, it would bring us much closer to the realization of "organ-on-chip" that can create tissues and organs with cells on a substrate. Based on the novel concept of electrostatically attaching two types of positively and negatively charged microgels, we developed a highly biocompatible biohybrid 3D fabrication method by using the original method that aggregate non-magnetic particles with a magnetic field. Furthermore, by adding thermo-responsive polymers to the microgels, it was confirmed that the microgel aggregate functioned as a heat-shrinkable actuator.
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