|Budget Amount *help
¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2020: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
|Outline of Final Research Achievements
Germ cells are the only cell type that transmits genetic information to the next generation. In Drosophila, germ cell formation relies on the germ plasm, which is assembled during oogenesis at the posterior pole of the oocyte. We have investigated mechanisms by which the germ plasm is assembled and maintained, as well as those by which germ cell development is operated. Series of our studies have provided several new concepts, including a new physiological roles of yolk uptake into the oocyte and transient transcriptional quiescence in newly formed germ cells. We have also identified new maternal factors that are involved in germ plasm assembly. Studies on these new factors will provide new insights into mechanisms underlying germ cell development in the future.