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Interdisciplinary analysis of the pre-Ainu skeletons excavated in Hokkaido

Research Project

Project/Area Number 17H03737
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Physical anthropology
Research InstitutionUniversity of Yamanashi

Principal Investigator

ADACHI Noboru  山梨大学, 大学院総合研究部, 教授 (60282125)

Co-Investigator(Kenkyū-buntansha) 近藤 修  東京大学, 大学院理学系研究科(理学部), 准教授 (40244347)
角田 恒雄  山梨大学, 大学院総合研究部, 特任助教 (80446575)
神澤 秀明  独立行政法人国立科学博物館, 人類研究部, 研究員 (80734912)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2019: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Keywordsプレアイヌ / オホーツク文化 / 擦文文化 / 縄文 / ゲノム / プレ・アイヌ / 続縄文 / 擦文 / 縄文文化 / 続縄文文化 / 北海道
Outline of Final Research Achievements

In the period of this grant, we published 11 articles related to this study. Among these, we clarified that genetic influences of the Native Siberians and main-island Japanese as well as the Jomon people are considered to be significant in the Ainu people. This finding strongly recommends amendment of the widely accepted dual-structure model for the population history of the Japanese,in which the Ainu are assumed to be the direct descendants of the Jomon people.
Moreover,we determined the high-depth nuclear genome sequences of a Funadomari Jomon female (F23). This data provided insights into the history and reconstructions of the ancient human population structures in East Eurasia, and the F23 genome data can be considered as the Jomon Reference Genome for future studies.

Academic Significance and Societal Importance of the Research Achievements

日本列島の人類集団の成立を説明する説として広く受け入れられている二重構造モデルでは、アイヌは縄文時代人のほぼ直接の子孫であると説明されてきた。しかし、我々の研究で、アイヌは縄文時代人以外に、シベリア先住民族および本州日本人の遺伝的影響も大きく受けていることが明らかとなった。また、北海道船泊遺跡出土縄文後期人について、世界初となる現代人レベルでの高精度ゲノム解析に成功した。この成果は縄文時代人の遺伝的特徴を考える上で重要なことは勿論、日本列島人の成立を遺伝子から考える上で基盤・礎石となるデータである。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report

Research Products

(28 results)

All 2020 2019 2018 2017 Other

All Journal Article (12 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 10 results,  Open Access: 7 results) Presentation (14 results) (of which Invited: 5 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Late Jomon male and female genome sequences from the Funadomari site in Hokkaido, Japan2019

    • Author(s)
      Kanzawa-Kiriyama Hideaki、Jinam Timothy A.、Kawai Yosuke、Sato Takehiro、Hosomichi Kazuyoshi、Tajima Atsushi、Adachi Noboru、Matsumura Hirofumi、Kryukov Kirill、Saitou Naruya、Shinoda Ken-Ichi
    • Journal Title

      AS

      Volume: 127 Issue: 2 Pages: 83-108

    • DOI

      10.1537/ase.190415

    • NAID

      130007696474

    • ISSN
      0918-7960, 1348-8570
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Conjugal cerebellar type of multiple system atrophy: Person-to-person transmission?2019

    • Author(s)
      Nan Haitian、Natori Takahiro、Ichinose Yuta、Koh Kishin、Kobayashi Fumikazu、Shindo Kazumasa、Hashiyada Masaki、Adachi Noboru、Yamagata Zentaro、Takiyama Yoshihisa
    • Journal Title

      Parkinsonism and Related Disorders

      Volume: 69 Pages: 68-70

    • DOI

      10.1016/j.parkreldis.2019.10.026

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic characteristics of Yayoi people in Northwestern Kyushu2019

    • Author(s)
      篠田謙一,神澤秀明,角田恒雄,安達登
    • Journal Title

      AS (J. Ser.)

      Volume: 127, 1 Issue: 1 Pages: 25-43

    • DOI

      10.1537/asj.1904231

    • NAID

      130007668339

    • ISSN
      1344-3992, 1348-8813
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 韓国加徳島しょう項遺跡出土人骨のDNA分析2019

    • Author(s)
      篠田謙一,神澤秀明,角田恒雄,安達 登.
    • Journal Title

      韓国文化財研究院論文集・文物

      Volume: 9 Pages: 167-206

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mitochondrial DNA analysis of the human skeletons excavated from the Shomyoji shell midden site, Kanagawa, Japan2019

    • Author(s)
      Ryohei Takahashi, Ryoko Koibuchi, Fumiko Saeki, Yasuo Hagihara, Minoru Yoneda, Noboru Adachi, Takashi Nara
    • Journal Title

      AS

      Volume: 127 Issue: 1 Pages: 65-72

    • DOI

      10.1537/ase.190307

    • NAID

      130007636539

    • ISSN
      0918-7960, 1348-8570
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mitochondrial DNA analysis of human skeletal remains excavated from the Iwashita Cave and Shimo-motoyama rock shelter sites2019

    • Author(s)
      篠田 謙一, 神澤 秀明, 角田 恒雄, 安達 登
    • Journal Title

      AS (J. Ser.)

      Volume: Vol.125 Issue: 1 Pages: 49-63

    • DOI

      10.1537/asj.170509

    • NAID

      130006832294

    • ISSN
      1344-3992, 1348-8813
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] ranio-morphometric and aDNA corroboration of the Austronesian dispersal model in ancient Island Southeast Asia: Support from Gua Harimau, Indonesia2018

    • Author(s)
      Matsumura H, Shinoda K, Shimanjuntak T, Oktaviana A A, Noerwidi S, SofianH O, Prastiningtyas D, NguyenL C, Kakuda T, Kanzawa-Kiriyama H, Adachi N, Hung H-C, Fan X, Wu X, Willis A and Oxenham MF
    • Journal Title

      PLOS ONE

      Volume: 13(6) Pages: 1-25

    • DOI

      10.1371/journal.pone.0198689

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 古代DNA解析の見地からみた骨考古学2018

    • Author(s)
      安達 登
    • Journal Title

      季刊考古学

      Volume: 143 Pages: 89-91

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Ethnic derivation of the Ainu inferred from ancient mitochondrial DNA data2018

    • Author(s)
      Adachi N, Kakuda T, Takahashi R, Kanzawa-Kiriyama H, Shinoda K
    • Journal Title

      Am J Phys Anthropol

      Volume: 165 Pages: 139-148

    • DOI

      10.1002/ajpa.23338

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The detailed examination of the human ancient mitochondrial DNA using the Ion PGM? System2017

    • Author(s)
      Hashiyada Masaki、Adachi Noboru、Akane Atsushi、Matsumoto Tomohiro、Yoshimura Sumitaka
    • Journal Title

      Forensic Science International: Genetics Supplement Series

      Volume: 6

    • DOI

      10.1016/j.fsigss.2017.09.061

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 東日本古墳時代人のミトコンドリアDNA解析2017

    • Author(s)
      安達 登, 角田恒雄, 高橋遼平, 神澤秀明, 篠田謙一
    • Journal Title

      DNA多型

      Volume: 25 Pages: 135-137

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 沖縄先史人はどこから来たのか-DNAが語る集団の系統-2017

    • Author(s)
      篠田謙一, 神澤秀明, 角田恒雄, 安達 登
    • Journal Title

      科学

      Volume: 87 Pages: 555-558

    • Related Report
      2017 Annual Research Report
  • [Presentation] 灰塚山古墳出土人骨のミトコンドリアDNA解析.2019

    • Author(s)
      安達 登
    • Organizer
      東北学院大学博物館開館10周年記念特別展記念シンポジウム「古墳時代王者はどんな人?」
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 新規プライマーセットを用いた高感度性別判定法の開発.2019

    • Author(s)
      藤本佳那, 藤井元人, 猩々英紀, 角田恒雄,上木耕一郎, 安達 登.
    • Organizer
      日本DNA多型学会第28回学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 肥満低換気症候群が急死に関与した可能性が高いと考えられた一例.2019

    • Author(s)
      安達 登,角田恒雄, 猩々英紀, 安達美佳.
    • Organizer
      第41回日本法医学会学術中部地方集会.
    • Related Report
      2019 Annual Research Report
  • [Presentation] 日本列島古代人のCPT1A欠損症関連遺伝子変異の分布.2019

    • Author(s)
      安達 登,神澤秀明、佐藤丈寬、角田恒雄, 篠田謙一.
    • Organizer
      第73回日本人類学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 山形県置賜地方羽山古墳から出土した終末期古墳時代人骨.2019

    • Author(s)
      佐伯史子, 安達 登,澤田純明, 小林貴宏.
    • Organizer
      第73回日本人類学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Multiplex APLP system for haplogrouping of newly discovered mtDNA lineages.2019

    • Author(s)
      藤井元人、神澤秀明、安達 登.
    • Organizer
      第103次日本法医学会学術全国集会.
    • Related Report
      2019 Annual Research Report
  • [Presentation] 我が国の国家形成期における人類集団の遺伝的転換2019

    • Author(s)
      安達 登
    • Organizer
      第124回日本解剖学会学術全国集会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] ミトコンドリアDNAからみた縄文時代人の遺伝的特徴とその地域差2018

    • Author(s)
      安達 登
    • Organizer
      第72回日本人類学会大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 神奈川県横浜市称名寺D貝塚第3地点出土人骨のミトコンドリアDNA解析2018

    • Author(s)
      高橋遼平, 安達 登, 鯉渕凌子, 佐伯史子, 米田 穣, 奈良貴史
    • Organizer
      日本DNA多型学会第27回学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 灰塚山古墳出土人骨のミトコンドリアDNA解析2018

    • Author(s)
      安達 登
    • Organizer
      日本考古学協会第84回総会研究発表
    • Related Report
      2018 Annual Research Report
  • [Presentation] ミトコンドリアDNA研究で探るアイヌ民族の成り立ち2017

    • Author(s)
      安達 登
    • Organizer
      日本考古学会公開講演会「考古学・人類学とアイヌ民族」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 野々前貝塚・長谷堂貝塚出土人骨のDNA分析2017

    • Author(s)
      安達 登
    • Organizer
      公開シンポジウム「最新研究からよみがえる縄文時代人」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 東日本古墳時代人のミトコンドリアDNA解析(第2報)2017

    • Author(s)
      安達 登, 神澤秀明, 角田恒雄, 高橋遼平, 篠田謙一
    • Organizer
      第71回日本人類学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 混合斑痕からの個人識別を目的としたミトコンドリアDNA検査法の開発2017

    • Author(s)
      安達 登,角田恒雄,高橋遼平, 猩々英紀
    • Organizer
      第39回日本法医学会学術中部地方集会
    • Related Report
      2017 Annual Research Report
  • [Remarks] 山梨大学医学部法医学講座

    • URL

      https://www.med.yamanashi.ac.jp/social/legal0me/

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report 2017 Annual Research Report
  • [Patent(Industrial Property Rights)] 核酸抽出装置及び核酸抽出方法2020

    • Inventor(s)
      石原敬三、赤池 東、細谷明宏、安達 登、角田恒雄、田中隆弘
    • Industrial Property Rights Holder
      山梨大学、アイドラス、メイコー、加藤電器製作所
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-029141
    • Filing Date
      2020
    • Related Report
      2019 Annual Research Report

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Published: 2017-04-28   Modified: 2021-02-19  

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