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Estimating effectiveness and its mechanism of case isolation

Research Project

Project/Area Number 17H04701
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Life / Health / Medical informatics
Research InstitutionKyoto University (2020-2021)
Hokkaido University (2017-2019)

Principal Investigator

Nishiura Hiroshi  京都大学, 医学研究科, 教授 (70432987)

Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥24,440,000 (Direct Cost: ¥18,800,000、Indirect Cost: ¥5,640,000)
Fiscal Year 2020: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2019: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2018: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2017: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Keywords感染症情報 / 疫学 / 数理モデル / 危機管理 / 保健情報 / 理論疫学 / 生物統計学
Outline of Final Research Achievements

Nonpharmaceutical interventions including case isolation is widely applicable to various infectious diseases to which vaccine and treatment are under development. However, the protective effect of case isolation has not been quantitatively clarified. The present study employed a mathematical approach to quantifying the secondary transmission phenomena as a function fo time since infection in the primary case. Formulating novel models and analyzing empirical epidemiological data, we have explicitly estimated the effectiveness of case isolation. During the project, a pandemic of novel coronavirus disease (COVID-19) started and relevant studies on COVID-19 were also conducted. We have shown that the serial interval of COVID-19 was as short as 5 days, which was close to the value of the incubation period.

Academic Significance and Societal Importance of the Research Achievements

隔離効果の推定手法を定式化し、2014年のナイジェリアにおけるエボラ出血熱流行データから隔離が2次感染を約46%減少させたことを実証した。また、新型コロナウイルス感染症では発症間隔と潜伏期間の値がほぼ同じ程度であり、同感染症の2次感染の多く(実際には50%程度)が発病前に起こっていることを示した。本情報は、新型コロナウイルス感染症の流行対策においては単なる早期診断と隔離だけでは流行を制御することはかなり難しいことを意味するものであった。本研究によって接触者追跡に基づく対策が無益なものにならないように遡り調査が実施され、同論文は2022年6月1日時点までに合計1066回の引用を受けた。

Report

(5 results)
  • 2021 Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (88 results)

All 2022 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (1 results) Journal Article (72 results) (of which Int'l Joint Research: 31 results,  Peer Reviewed: 70 results,  Open Access: 68 results) Presentation (14 results) (of which Int'l Joint Research: 5 results,  Invited: 6 results) Book (1 results)

  • [Int'l Joint Research] オックスフォード大学(英国)

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Transmission Network of Measles During the Yamagata Outbreak in Japan, 20172022

    • Author(s)
      Kobayashi Tetsuro、Nishiura Hiroshi
    • Journal Title

      Journal of Epidemiology

      Volume: 32 Issue: 2 Pages: 96-104

    • DOI

      10.2188/jea.JE20200455

    • NAID

      130008157948

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2022-02-05
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimation of R(t) based on illness onset data: An analysis of 1907?1908 smallpox epidemic in Tokyo2022

    • Author(s)
      Nakajo Ko、Nishiura Hiroshi
    • Journal Title

      Epidemics

      Volume: 38 Pages: 100545-100545

    • DOI

      10.1016/j.epidem.2022.100545

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reconstructing the transmission dynamics of varicella in Japan: an elevation of age at infection2022

    • Author(s)
      Suzuki Ayako、Nishiura Hiroshi
    • Journal Title

      PeerJ

      Volume: 10 Pages: e12767-e12767

    • DOI

      10.7717/peerj.12767

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Phenomenological and mechanistic models for predicting early transmission data of COVID-192021

    • Author(s)
      Miyama Takeshi、Hiroshi Nishiura
    • Journal Title

      Mathematical Biosciences and Engineering

      Volume: 19 Issue: 2 Pages: 2043-2055

    • DOI

      10.3934/mbe.2022096

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relative Reproduction Number of SARS-CoV-2 Omicron (B.1.1.529) Compared with Delta Variant in South Africa2021

    • Author(s)
      Nishiura Hiroshi、Ito Kimihito、Anzai Asami、Kobayashi Tetsuro、Piantham Chayada、Rodr?guez-Morales Alfonso J.
    • Journal Title

      Journal of Clinical Medicine

      Volume: 11 Issue: 1 Pages: 30-30

    • DOI

      10.3390/jcm11010030

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Not all fun and games: Potential incidence of SARS-CoV-2 infections during the Tokyo 2020 Olympic Games2021

    • Author(s)
      Linton Natalie M.、School of Public Health, Kyoto University, Kyoto, Japan、Jung Sung-mok、Nishiura Hiroshi、Graduate School of Medicine, Hokkaido University, Sapporo, Japan
    • Journal Title

      Mathematical Biosciences and Engineering

      Volume: 18 Issue: 6 Pages: 9685-9696

    • DOI

      10.3934/mbe.2021474

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Epidemic Risk of Dengue Fever in Japan: Climate Change and Seasonality2021

    • Author(s)
      Wang Xia、Nishiura Hiroshi
    • Journal Title

      Canadian Journal of Infectious Diseases and Medical Microbiology

      Volume: 2021 Pages: 1-13

    • DOI

      10.1155/2021/6699788

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Increasing rates of laparoscopic gastrointestinal surgery and decreasing rates of surgical site infections: an observational study in Japan from 2012?20172021

    • Author(s)
      Takahashi Tomoko、Nishiura Hiroshi
    • Journal Title

      BMC Surgery

      Volume: 21 Issue: 1

    • DOI

      10.1186/s12893-021-01373-2

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Assessing countermeasures during a hepatitis A virus outbreak among men who have sex with men2021

    • Author(s)
      Saito Ryohei、Imamura Akifumi、Nishiura Hiroshi
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 18 Issue: 1

    • DOI

      10.1186/s12976-021-00150-1

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Predicting the effective reproduction number of COVID-19: inference using human mobility, temperature, and risk awareness2021

    • Author(s)
      Jung Sung-mok、Endo Akira、Akhmetzhanov Andrei R.、Nishiura Hiroshi
    • Journal Title

      International Journal of Infectious Diseases

      Volume: 113 Pages: 47-54

    • DOI

      10.1016/j.ijid.2021.10.007

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Analysis of international traveler mobility patterns in Tokyo to identify geographic foci of dengue fever risk2021

    • Author(s)
      Yuan Baoyin、Lee Hyojung、Nishiura Hiroshi
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 18 Issue: 1

    • DOI

      10.1186/s12976-021-00149-8

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Long-term dynamics of <i>Norovirus</i> transmission in Japan, 2005?20192021

    • Author(s)
      Misumi Megumi、Nishiura Hiroshi
    • Journal Title

      PeerJ

      Volume: 9 Pages: e11769-e11769

    • DOI

      10.7717/peerj.11769

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimating COVID-19 cases infected with the variant alpha (VOC 202012/01): an analysis of screening data in Tokyo, January-March 20212021

    • Author(s)
      Murayama Hiroaki、Kayano Taishi、Nishiura Hiroshi
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 18 Issue: 1

    • DOI

      10.1186/s12976-021-00146-x

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exploring secondary SARS-CoV-2 transmission from asymptomatic cases using contact tracing data2021

    • Author(s)
      Nakajo Ko、Nishiura Hiroshi
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 18 Issue: 1

    • DOI

      10.1186/s12976-021-00144-z

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Predicted dominance of variant Delta of SARS-CoV-2 before Tokyo Olympic Games, Japan, July 20212021

    • Author(s)
      Ito Kimihito、Piantham Chayada、Nishiura Hiroshi
    • Journal Title

      Eurosurveillance

      Volume: 26 Issue: 27 Pages: 2100570-2100570

    • DOI

      10.2807/1560-7917.es.2021.26.27.2100570

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Recovery of antimicrobial susceptibility in methicillin-resistant <i>Staphylococcus aureus</i> (MRSA): a retrospective, epidemiological analysis in a secondary care hospital, Sapporo, Japan2021

    • Author(s)
      Koike Yuji、Nishiura Hiroshi
    • Journal Title

      PeerJ

      Volume: 9 Pages: e11644-e11644

    • DOI

      10.7717/peerj.11644

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimation of the Actual Incidence of Coronavirus Disease (COVID-19) in Emergent Hotspots: The Example of Hokkaido, Japan during February?March 20202021

    • Author(s)
      Akhmetzhanov Andrei R.、Mizumoto Kenji、Jung Sung-Mok、Linton Natalie M.、Omori Ryosuke、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 10 Issue: 11 Pages: 2392-2392

    • DOI

      10.3390/jcm10112392

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Assessing the geographic range of classical swine fever vaccinations by spatiotemporal modelling in Japan2021

    • Author(s)
      Yang Yichi、Nishiura Hiroshi
    • Journal Title

      Transboundary and Emerging Diseases

      Volume: 2021 Issue: 4 Pages: 1880-1889

    • DOI

      10.1111/tbed.14171

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Projecting a second wave of COVID-19 in Japan with variable interventions in high-risk settings2021

    • Author(s)
      Jung Sung-mok、Endo Akira、Kinoshita Ryo、Nishiura Hiroshi
    • Journal Title

      Royal Society Open Science

      Volume: 8 Issue: 3

    • DOI

      10.1098/rsos.202169

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Assessing Interventions against Coronavirus Disease 2019 (COVID-19) in Osaka, Japan: A Modeling Study2021

    • Author(s)
      Nakajo Ko、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 10 Issue: 6 Pages: 1256-1256

    • DOI

      10.3390/jcm10061256

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Predicting the cumulative number of disaster deaths during the early stage of earthquakes2021

    • Author(s)
      Fujimoto Marie、Nishiura Hiroshi
    • Journal Title

      Annals of Translational Medicine

      Volume: 9 Issue: 3 Pages: 241-241

    • DOI

      10.21037/atm-20-5784

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Localized end-of-outbreak determination for coronavirus disease 2019 (COVID-19): examples from clusters in Japan2021

    • Author(s)
      Linton Natalie M.、Akhmetzhanov Andrei R.、Nishiura Hiroshi
    • Journal Title

      International Journal of Infectious Diseases

      Volume: 105 Pages: 286-292

    • DOI

      10.1016/j.ijid.2021.02.106

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Transmissibility of asymptomatic COVID-19: Data from Japanese clusters2021

    • Author(s)
      Nakajo Ko、Nishiura Hiroshi
    • Journal Title

      International Journal of Infectious Diseases

      Volume: 105 Pages: 236-238

    • DOI

      10.1016/j.ijid.2021.02.065

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] “Go To Travel” Campaign and Travel-Associated Coronavirus Disease 2019 Cases: A Descriptive Analysis, July?August 20202021

    • Author(s)
      Anzai Asami、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 10 Issue: 3 Pages: 398-398

    • DOI

      10.3390/jcm10030398

    • NAID

      120006954099

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A method for estimating the transmissibility of influenza using serial cross-sectional seroepidemiological data2021

    • Author(s)
      Yang Yichi、Asai Yusuke、Nishiura Hiroshi
    • Journal Title

      Journal of Theoretical Biology

      Volume: 511 Pages: 110566-110566

    • DOI

      10.1016/j.jtbi.2020.110566

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identifying geographic areas at risk of rubella epidemics in Japan using seroepidemiological data2021

    • Author(s)
      Kayano Taishi、Lee Hyojung、Kinoshita Ryo、Nishiura Hiroshi
    • Journal Title

      International Journal of Infectious Diseases

      Volume: 102 Pages: 203-211

    • DOI

      10.1016/j.ijid.2020.09.1458

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Containment, Contact Tracing and Asymptomatic Transmission of Novel Coronavirus Disease (COVID-19): A Modelling Study2020

    • Author(s)
      Kinoshita Ryo、Anzai Asami、Jung Sung-mok、Linton Natalie M.、Miyama Takeshi、Kobayashi Tetsuro、Hayashi Katsuma、Suzuki Ayako、Yang Yichi、Akhmetzhanov Andrei R.、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 10 Pages: 3125-3125

    • DOI

      10.3390/jcm9103125

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Estimating the protective effect of case isolation with transmission tree reconstruction during the Ebola outbreak in Nigeria, 20142020

    • Author(s)
      Chan Yat Hin、Nishiura Hiroshi
    • Journal Title

      Journal of The Royal Society Interface

      Volume: 17 Issue: 169 Pages: 498-498

    • DOI

      10.1098/rsif.2020.0498

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Serial interval of novel coronavirus (COVID-19) infections2020

    • Author(s)
      Nishiura Hiroshi、Linton Natalie M.、Akhmetzhanov Andrei R.
    • Journal Title

      International Journal of Infectious Diseases

      Volume: 93 Pages: 284-286

    • DOI

      10.1016/j.ijid.2020.02.060

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data2020

    • Author(s)
      Linton Natalie M.、Kobayashi Tetsuro、Yang Yichi、Hayashi Katsuma、Akhmetzhanov Andrei R.、Jung Sung-mok、Yuan Baoyin、Kinoshita Ryo、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 2 Pages: 538-538

    • DOI

      10.3390/jcm9020538

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Quantifying the causal impact of funding bedside antigen testing on the incidence of respiratory syncytial virus infection in Japan: a difference-in-differences study2020

    • Author(s)
      Jung Sung-mok、Lee Hyojung、Yang Yichi、Nishiura Hiroshi
    • Journal Title

      Annals of Translational Medicine

      Volume: 8 Issue: 21 Pages: 1441-1441

    • DOI

      10.21037/atm-20-423

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Age and geographic dependence of Zika virus infection during the outbreak on Yap island, 20072020

    • Author(s)
      Endo A.、Graduate School of Medicine, Hokkaido University, Kita 15 Jo Nishi 7 Chome, Kita-ku, Sapporo 060-8638, Japan、Nishiura H.、Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, Bloomsbury, London WC1E 7HT, United Kingdom
    • Journal Title

      Mathematical Biosciences and Engineering

      Volume: 17 Issue: 4 Pages: 4115-4126

    • DOI

      10.3934/mbe.2020228

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Extent of Transmission of Novel Coronavirus in Wuhan, China, 20202020

    • Author(s)
      Nishiura Hiroshi、Jung Sung-mok、Linton Natalie M.、Kinoshita Ryo、Yang Yichi、Hayashi Katsuma、Kobayashi Tetsuro、Yuan Baoyin、Akhmetzhanov Andrei R.
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 2 Pages: 330-330

    • DOI

      10.3390/jcm9020330

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exploring Influenza Vaccine Uptake and Its Determinants among University Students: A Cross-Sectional Study2020

    • Author(s)
      Kawahara Yukako、Nishiura Hiroshi
    • Journal Title

      Vaccines

      Volume: 8 Issue: 1 Pages: 52-52

    • DOI

      10.3390/vaccines8010052

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Rate of Underascertainment of Novel Coronavirus (2019-nCoV) Infection: Estimation Using Japanese Passengers Data on Evacuation Flights2020

    • Author(s)
      Nishiura Hiroshi、Kobayashi Tetsuro、Yang Yichi、Hayashi Katsuma、Miyama Takeshi、Kinoshita Ryo、Linton Natalie M.、Jung Sung-mok、Yuan Baoyin、Suzuki Ayako、Akhmetzhanov Andrei R.
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 2 Pages: 419-419

    • DOI

      10.3390/jcm9020419

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Initial Cluster of Novel Coronavirus (2019-nCoV) Infections in Wuhan, China Is Consistent with Substantial Human-to-Human Transmission2020

    • Author(s)
      Nishiura Hiroshi、Linton Natalie M.、Akhmetzhanov Andrei R.
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 2 Pages: 488-488

    • DOI

      10.3390/jcm9020488

    • Related Report
      2019 Annual Research Report
    • Open Access / Int'l Joint Research
  • [Journal Article] Real-Time Estimation of the Risk of Death from Novel Coronavirus (COVID-19) Infection: Inference Using Exported Cases2020

    • Author(s)
      Jung Sung-mok、Akhmetzhanov Andrei R.、Hayashi Katsuma、Linton Natalie M.、Yang Yichi、Yuan Baoyin、Kobayashi Tetsuro、Kinoshita Ryo、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 2 Pages: 523-523

    • DOI

      10.3390/jcm9020523

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Communicating the Risk of Death from Novel Coronavirus Disease (COVID-19)2020

    • Author(s)
      Kobayashi Tetsuro、Jung Sung-mok、Linton Natalie M.、Kinoshita Ryo、Hayashi Katsuma、Miyama Takeshi、Anzai Asami、Yang Yichi、Yuan Baoyin、Akhmetzhanov Andrei R.、Suzuki Ayako、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 2 Pages: 580-580

    • DOI

      10.3390/jcm9020580

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Assessing the Impact of Reduced Travel on Exportation Dynamics of Novel Coronavirus Infection (COVID-19)2020

    • Author(s)
      Anzai Asami、Kobayashi Tetsuro、Linton Natalie M.、Kinoshita Ryo、Hayashi Katsuma、Suzuki Ayako、Yang Yichi、Jung Sung-mok、Miyama Takeshi、Akhmetzhanov Andrei R.、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 2 Pages: 601-601

    • DOI

      10.3390/jcm9020601

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Epidemiological Identification of A Novel Pathogen in Real Time: Analysis of the Atypical Pneumonia Outbreak in Wuhan, China, 2019?20202020

    • Author(s)
      Jung Sung-mok、Kinoshita Ryo、Thompson Robin N.、Linton Natalie M.、Yang Yichi、Akhmetzhanov Andrei R.、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 3 Pages: 637-637

    • DOI

      10.3390/jcm9030637

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Backcalculating the Incidence of Infection with COVID-19 on the Diamond Princess2020

    • Author(s)
      Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 3 Pages: 657-657

    • DOI

      10.3390/jcm9030657

    • Related Report
      2019 Annual Research Report
    • Open Access
  • [Journal Article] Predicting the Epidemiological Dynamics of Lung Cancer in Japan2019

    • Author(s)
      Yamaguchi Takayuki、Nishiura Hiroshi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 8 Issue: 3 Pages: 326-326

    • DOI

      10.3390/jcm8030326

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fluoroquinolone consumption and Escherichia coli resistance in Japan: an ecological study2019

    • Author(s)
      Terahara Fumitaka、Nishiura Hiroshi
    • Journal Title

      BMC Public Health

      Volume: 19 Issue: 1 Pages: 1-5

    • DOI

      10.1186/s12889-019-6804-3

    • NAID

      120006633300

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Spatial epidemiological determinants of severe fever with thrombocytopenia syndrome in Miyazaki, Japan: a GWLR modeling study2019

    • Author(s)
      Yasuo Kazuhiro、Nishiura Hiroshi
    • Journal Title

      BMC Infectious Diseases

      Volume: 19 Issue: 1 Pages: 1-5

    • DOI

      10.1186/s12879-019-4111-3

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Investigation of the Proportion of Diagnosed People Living with HIV/AIDS among Foreign Residents in Japan2019

    • Author(s)
      Shimizu Kazuki、Nishiura Hiroshi、Imamura Akifumi
    • Journal Title

      Journal of Clinical Medicine

      Volume: 8 Issue: 6 Pages: 804-804

    • DOI

      10.3390/jcm8060804

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimating the annual risk of tuberculosis infection in Japan from interferon-gamma release assay data2019

    • Author(s)
      Hamaguchi Yuko、Yamaguchi Takayuki、Nishiura Hiroshi
    • Journal Title

      Journal of Theoretical Biology

      Volume: 460 Pages: 125-133

    • DOI

      10.1016/j.jtbi.2018.10.017

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimating the Asymptomatic Ratio of Norovirus Infection During Foodborne Outbreaks With Laboratory Testing in Japan2018

    • Author(s)
      Miura F, Matsuyama R, Nishiura H
    • Journal Title

      Journal of Epidemiology

      Volume: 28 Issue: 9 Pages: 382-387

    • DOI

      10.2188/jea.JE20170040

    • NAID

      130007481555

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2018-09-05
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Capturing the transmission dynamics of the 2009 Japanese pandemic influenza H1N1 in the presence of heterogeneous immunity2018

    • Author(s)
      Endo Akira、Ejima Keisuke、Nishiura Hiroshi
    • Journal Title

      Annals of Epidemiology

      Volume: 28 Issue: 5 Pages: 293-300.e1

    • DOI

      10.1016/j.annepidem.2018.02.011

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Real-time quantification of the next-generation matrix and age-dependent forecasting of pandemic influenza H1N1 2009 in Japan2018

    • Author(s)
      Ejima Keisuke、Nishiura Hiroshi
    • Journal Title

      Annals of Epidemiology

      Volume: 28 Issue: 5 Pages: 301-308

    • DOI

      10.1016/j.annepidem.2018.02.010

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The Role of Migration in Maintaining the Transmission of Avian Influenza in Waterfowl: A Multisite Multispecies Transmission Model along East Asian-Australian Flyway2018

    • Author(s)
      Akira Endo and Hiroshi Nishiura
    • Journal Title

      Canadian Journal of Infectious Diseases and Medical Microbiology

      Volume: 2018 Pages: 3420535-3420535

    • DOI

      10.1155/2018/3420535

    • NAID

      120006484262

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Assessing the Effectiveness and Cost-Benefit of Test-and-Vaccinate Policy for Supplementary Vaccination against Rubella with Limited Doses2018

    • Author(s)
      Saito MM, Ejima K, Kinoshita R, Nishiura H
    • Journal Title

      Int J Environ Res Public Health

      Volume: 15 Issue: 4 Pages: 572-572

    • DOI

      10.3390/ijerph15040572

    • NAID

      120006522670

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Uncertainty and sensitivity analysis of the basic reproduction number of diphtheria: a case study of a Rohingya refugee camp in Bangladesh, November-December 2017.2018

    • Author(s)
      Matsuyama R, Akhmetzhanov AR, Endo A, Lee H, Yamaguchi T, Tsuzuki S, Nishiura H
    • Journal Title

      PeerJ

      Volume: - Pages: e4583-e4583

    • DOI

      10.7717/peerj.4583

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Household transmission of acute gastroenteritis during the winter season in Japan2018

    • Author(s)
      Matsuyama Ryota、Miura Fuminari、Tsuzuki Shinya、Nishiura Hiroshi
    • Journal Title

      Journal of International Medical Research

      Volume: 46 Issue: 7 Pages: 2866-2874

    • DOI

      10.1177/0300060518776451

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments2018

    • Author(s)
      Belser Jessica A.、Barclay Wendy、Barr Ian、Fouchier Ron A.M.、Matsuyama Ryota、Nishiura Hiroshi、Peiris Malik、Russell Charles J.、Subbarao Kanta、Zhu Huachen、Yen Hui-Ling
    • Journal Title

      Emerging Infectious Diseases

      Volume: 24 Issue: 6 Pages: 965-971

    • DOI

      10.3201/eid2406.172114

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Modelling the impact of correlations between condom use and sexual contact pattern on the dynamics of sexually transmitted infections2018

    • Author(s)
      Yamamoto Nao、Ejima Keisuke、Nishiura Hiroshi
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 15 Issue: 1

    • DOI

      10.1186/s12976-018-0078-9

    • NAID

      120006491519

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Estimating the actual importation risk of dengue virus infection among Japanese travelers2018

    • Author(s)
      Yuan Baoyin、Nishiura Hiroshi
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 6 Pages: 0198734-0198734

    • DOI

      10.1371/journal.pone.0198734

    • NAID

      120006502510

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Modeling the elevated risk of yellow fever among travelers visiting Brazil, 20182018

    • Author(s)
      Sakamoto Yohei、Yamaguchi Takayuki、Yamamoto Nao、Nishiura Hiroshi
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 15 Issue: 1 Pages: 9-9

    • DOI

      10.1186/s12976-018-0081-1

    • NAID

      120006502507

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An investigation of a measles outbreak in Japan and Taiwan, China, March-May 20182018

    • Author(s)
      Shimizu Kazuki、Kinoshita Ryo、Yoshii Keita、Akhmetzhanov Andrei、Jung Sungmok、Lee Hyojung、Nishiura Hiroshi
    • Journal Title

      Western Pacific Surveillance and Response Journal

      Volume: 9 Issue: 3 Pages: 25-31

    • DOI

      10.5365/wpsar.2018.9.2.005

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Measles control in a measles-eliminated country, Japan2018

    • Author(s)
      Kinoshita Ryo、Shimizu Kazuki、Nishiura Hiroshi
    • Journal Title

      Travel Medicine and Infectious Disease

      Volume: 25 Pages: 8-9

    • DOI

      10.1016/j.tmaid.2018.08.006

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Demographic supply-demand imbalance in industrial structure in the super-aged nation Japan2018

    • Author(s)
      Kishida Naoki、Nishiura Hiroshi
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 15 Issue: 1 Pages: 19-19

    • DOI

      10.1186/s12976-018-0091-z

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Real Time Forecasting of Measles Using Generation-dependent Mathematical Model in Japan, 20182018

    • Author(s)
      Akhmetzhanov Andrei R.、Lee Hyojung、Jung Sung-mok、Kinoshita Ryo、Shimizu Kazuki、Yoshii Keita、Nishiura Hiroshi
    • Journal Title

      PLoS Currents

      Volume: 10 Pages: 1-6

    • DOI

      10.1371/currents.outbreaks.3cc277d133e2d6078912800748dbb492

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Reconstructing the transmission dynamics of rubella in Japan, 2012-20132018

    • Author(s)
      Saito Masaya M.、Nishiura Hiroshi、Higuchi Tomoyuki
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 10 Pages: 0205889-0205889

    • DOI

      10.1371/journal.pone.0205889

    • NAID

      120006541894

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Environmental Drivers of Bacillus-Positive Blood Cultures in a Cancer Hospital, Sapporo, Japan2018

    • Author(s)
      Fujita Takahiro、Nishiura Hiroshi
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 15 Issue: 10 Pages: 2201-2201

    • DOI

      10.3390/ijerph15102201

    • NAID

      120006545957

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The impact of pneumococcal vaccination on pneumonia mortality among the elderly in Japan: a difference-in-difference study2018

    • Author(s)
      Jung Sung-mok、Lee Hyojung、Nishiura Hiroshi
    • Journal Title

      PeerJ

      Volume: 6 Pages: e6085-e6085

    • DOI

      10.7717/peerj.6085

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Forecasting the size and peak of cholera epidemic in Yemen, 20172018

    • Author(s)
      Nishiura H, Tsuzuki S, Asai Y
    • Journal Title

      Future Microbiology

      Volume: 13 Issue: 4 Pages: 399-402

    • DOI

      10.2217/fmb-2017-0244

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Joint estimation of the transmissibility and severity of Ebola virus disease in real time.2018

    • Author(s)
      Asai Y, Nishiura H.
    • Journal Title

      Journal of Biological Systems

      Volume: 25 Issue: 04 Pages: 587-603

    • DOI

      10.1142/s0218339017400022

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Infectious disease risks among refugees from North Korea2017

    • Author(s)
      Hiroshi Nishiura, Hyojung Lee, Baoyin Yuan, Akira Endo, Andrei R.Akhmetzhanov, GerardoChowell
    • Journal Title

      International Journal of Infectious Diseases

      Volume: 66 Pages: 22-25

    • DOI

      10.1016/j.ijid.2017.10.021

    • NAID

      120006406687

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Unrecognized Subclinical Infection with Tickborne Encephalitis Virus, Japan2017

    • Author(s)
      Kentaro Yoshii, Reiji Kojima, and Hiroshi Nishiura
    • Journal Title

      Emerging Infectious Diseases

      Volume: 23 Issue: 10 Pages: 1753-1754

    • DOI

      10.3201/eid2310.170918

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dynamics of the pneumonic plague epidemic in Madagascar, August to October 20172017

    • Author(s)
      Tsuzuki S, Lee H, Miura F, Chan YH, Jung S, Akhmetzhanov AR, Nishiura H.
    • Journal Title

      Eurosurveillance

      Volume: 22 Issue: 46 Pages: 17-00710

    • DOI

      10.2807/1560-7917.es.2017.22.46.17-00710

    • NAID

      120006380365

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Transmission dynamics of cholera in Yemen, 2017: a real time forecasting2017

    • Author(s)
      Nishiura H, Tsuzuki S, Yuan B, Yamaguchi T, Asai Y
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 14 Issue: 1 Pages: 14-14

    • DOI

      10.1186/s12976-017-0061-x

    • NAID

      120006352210

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Recrudescence of Ebola virus disease outbreak in West Africa, 2014-20162017

    • Author(s)
      Lee H, Nishiura H
    • Journal Title

      International Journal of Infectious Diseases

      Volume: 64 Pages: 90-92

    • DOI

      10.1016/j.ijid.2017.09.013

    • NAID

      120006373734

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Test-and-treat approach to HIV/AIDS: A primer for mathematical modeling.2017

    • Author(s)
      Nah K, Nishiura H, Tsuchiya N, Asai Y, Imamura A
    • Journal Title

      Theoretical Biology and Medical Modelling

      Volume: 14 Issue: 1 Pages: 16-16

    • DOI

      10.1186/s12976-017-0062-9

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 気候変動による健康影響予測と適応 -デング熱、熱中症、新型コロナウイルス感染症-2022

    • Author(s)
      西浦博
    • Organizer
      第92回日本衛生学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Using epidemiological models for policy making: Pros and cons of bringing mathematical models to decision making process, .2022

    • Author(s)
      Nishiura H
    • Organizer
      2022 AAAS Annual Meeting
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 新型コロナウイルス感染症のクラスター形成リスクの推定, .2022

    • Author(s)
      西浦博
    • Organizer
      第32回日本疫学会学術総会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] オミクロン株の伝播と重症化の数理モデル2022

    • Author(s)
      西浦博
    • Organizer
      MIMS共同研究集会「現象と数理モデル. 数理モデリング学の形成に向けて」
    • Related Report
      2020 Annual Research Report
  • [Presentation] COVID-19の実効再生産数に関する時系列データからの異常検出,2021

    • Author(s)
      西浦博.
    • Organizer
      第80回日本公衆衛生学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 新型コロナウイルス感染症感染の実像と対策2021

    • Author(s)
      西浦博
    • Organizer
      第80回日本公衆衛生学会学術総会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Decomposing the mechanism of COVID-19 transmission2021

    • Author(s)
      Nishiura H
    • Organizer
      Korean Society for Industrial and Applied Mathematics
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 新型コロナウイルス感染症の疫学、数理モデルと今後2021

    • Author(s)
      西浦博.
    • Organizer
      第31回日本産業衛生学会全国協議会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 感染症数理モデルを利用した新型コロナウイルス感染症の現状分析、評価と予測2021

    • Author(s)
      西浦博
    • Organizer
      第91回日本感染症学会西日本地方会学術集会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 数理モデルを活用した在留外国人の在留年数別人口再構築と出生国別の結核リスクの推定2019

    • Author(s)
      西浦博、安齋麻美
    • Organizer
      日本人口学会第71回大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Estimation of the effective reproduction number of a measles outbreak in Guinea, 20172019

    • Author(s)
      Natalie Linton, Hiroshi Nishiura
    • Organizer
      Innovative Mathematical Modeling for the Analysis of Infectious Disease Data (IMAID 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ascertaining the End of Ebola Virus2018

    • Author(s)
      Hiroshi Nishiura
    • Organizer
      The 12th AIMS Conference on Dynamical Systems Differential Equations and Applications
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Metapopulation epidemic model fitted to spatiotemporal spread of rubella in Japan, 2012-132018

    • Author(s)
      Hiroshi Nishiura
    • Organizer
      The Society for Mathematical Biology & the Japanese Society for Mathematical Biology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Estimating the reproduction number from importation time2018

    • Author(s)
      Hiroshi Nishiura
    • Organizer
      第77回日本公衆衛生学会
    • Related Report
      2018 Annual Research Report
  • [Book] 感染症疫学のためのデータ分析入門2021

    • Author(s)
      西浦博
    • Total Pages
      240
    • Publisher
      金芳堂
    • Related Report
      2020 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2023-01-30  

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