|Budget Amount *help
¥24,700,000 (Direct Cost: ¥19,000,000、Indirect Cost: ¥5,700,000)
Fiscal Year 2020: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2019: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2018: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2017: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
|Outline of Final Research Achievements
In plants, chloroplasts are exposed to the damage caused by sunlight during photosynthesis-dependent growth. After photooxidative damage, chloroplasts are degraded in their entirety via an autophagy pathway termed chlorophagy. This study addressed the induction mechanisms and molecular players for chlorophagy that degrades photodamaged chloroplasts. Through the combination between reverse genetics approaches and microscopy observations, we revealed that what types of chloroplasts are targeted as a selective substrate of chlorophagy. Furthermore, to find the unknown genes regulating chlorophagy, we performed forward genetics analyzes, and identified some candidate genes that are specifically required for chlorophagy.