Co-Investigator(Kenkyū-buntansha) |
百瀬 敏光 国際医療福祉大学, 医学部, 教授 (20219992)
羽場 宏光 国立研究開発法人理化学研究所, 仁科加速器科学研究センター, 室長 (60360624)
鎌田 圭 東北大学, 未来科学技術共同研究センター, 准教授 (60639649)
島添 健次 東京大学, 大学院工学系研究科(工学部), 特任准教授 (70589340)
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Budget Amount *help |
¥205,790,000 (Direct Cost: ¥158,300,000、Indirect Cost: ¥47,490,000)
Fiscal Year 2021: ¥31,200,000 (Direct Cost: ¥24,000,000、Indirect Cost: ¥7,200,000)
Fiscal Year 2020: ¥34,580,000 (Direct Cost: ¥26,600,000、Indirect Cost: ¥7,980,000)
Fiscal Year 2019: ¥40,560,000 (Direct Cost: ¥31,200,000、Indirect Cost: ¥9,360,000)
Fiscal Year 2018: ¥50,310,000 (Direct Cost: ¥38,700,000、Indirect Cost: ¥11,610,000)
Fiscal Year 2017: ¥49,140,000 (Direct Cost: ¥37,800,000、Indirect Cost: ¥11,340,000)
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Outline of Final Research Achievements |
Conventional gamma-ray imaging methods suffer from fundamental limitation arising from their principles. For example, the spatial resolution of PET and the detection efficiency of SPECT are restricted by the positron range and the collimator, respectively. Our new imaging method based on temporal and spatial correlation among multiple gamma rays can identify gamma-ray emission point from only one event. The spatial resolution of the method is not affected by a positron range. In this research, we have found such nuclides that emit multiple gamma rays in series. We have started from the establishment of each technique and finally fabricated an imaging system for multiple gamma ray coincident imaging. Then we have applied the system to visualize phantom, mouse scan, and proven the reconstruction-free gamma-ray imaging. We have obtained the peptide accumulation image of the tumor region with radioisotopes.
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