Ultility of prelaod stress echocardiography in patrients with chronic heart failure
Project/Area Number |
17K01412
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical systems
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Research Institution | The University of Tokushima |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
山田 博胤 徳島大学, 大学院医歯薬学研究部(医学域), 特任教授 (40380084)
瀬野 弘光 徳島大学, 病院, 医員 (10794026)
|
Project Period (FY) |
2021-01-01 – 2022-03-31
|
Project Status |
Completed (Fiscal Year 2021)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | 心不全 / 心エコー / 下肢陽圧 / リスク層別化 / 血行動態 / 予後 / HFpEF / 大動脈弁狭窄症 / 左室拡張能 / 左房機能 / 医用超音波システム / 臨床心臓学 |
Outline of Research at the Start |
本研究は、下肢陽圧負荷試験による前負荷増大に対する左室拡張能応答を評価することで左室コンプライアンスを推定し,下肢陽圧負荷試験で心不全悪化の高リスク群と判断された患者に対し心不全の追加治療を行う事が,心不全患者の心不全再入院および心血管死の減少に有用であるかを前向きに検討する事を目的としている。
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Outline of Final Research Achievements |
Our research group first examined the usefulness of the positive pressure echocardiography in patients with heart failure with preserved left ventricular ejection fraction. The present study shows that the positive pressure echocardiography enables us to detect a high-risk group for worsening heart failure by measuring hemodynamic changes when preload increases.
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Academic Significance and Societal Importance of the Research Achievements |
心不全の予後は不良であり,早期の心機能障害を検出し治療介入をおこなう必要がある.本研究を通じて,下肢陽圧負荷心エコー図検査が高い安全性を有しており,左室駆出率の保たれた患者における心不全悪化の高リスク群の検出に有用であることを示すことができた.拡張障害の早期の段階で治療介入をおこなうことで将来の心不全悪化を減らせる可能性がある.
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Report
(4 results)
Research Products
(7 results)
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[Presentation] Right Ventricular Contractile Function Predicts Cardiac Events in Passive and Reactive Pulmonary Hypertension2018
Author(s)
Yoshihito Saijo, Kenya Kusunose,Hirotsugu Yamada, Susumu Nishio, Yuta Torii, Yukina Hirata, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata
Organizer
Americcan Heart Association Scientific Sessions 2018
Related Report
Int'l Joint Research
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[Presentation] Anthracyclines induce early changes in localized left ventricular dysfunction2018
Author(s)
Yoshihito Saijo, Kenya Kusunose, Hirotsugu Yamada, Susumu Nishio, Hiromitsu Seno, Kumiko Suto, Rie Ueno, Yutaka Kawabata, Hiroyuki Ito, Takafumi Todoroki, Tomomi Matsuura, Takayuki Ise, Takeshi Tobiume, Koji Yamaguchi, Shusuke Yagi, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata.
Organizer
日本循環器学会
Related Report
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