Mid-infrared pulse generation and shaping in engineered quasi-phase-matched nonlinear crystals for protein dynamics control

• Project/Area Number: 17K05077
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Optical engineering, Photon science
• Research Institution: Saitama University (2019-2021); Osaka University (2017-2018)
• Principal Investigator: Nakamura Ryosuke 埼玉大学, 理工学研究科, 特任准教授 (70379147)
• Co-Investigator(Kenkyū-buntansha): 神村 共住 大阪工業大学, 工学部, 教授 (40353338) ; 梅村 信弘 公立千歳科学技術大学, 理工学部, 准教授 (40580098)
• Project Period (FY): 2017-04-01 – 2022-03-31
• Project Status: Completed (Fiscal Year 2021)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 赤外レーザ / 準周期疑似位相整合 / 赤外レーザー / 中赤外光

Outline of Final Research Achievements

In this study, we investigate engineered quasi-phase-matching structures that can simultaneously realize differential frequency mixing and pulse shaping in the mid-infrared region for artificially controlling structural transitions in proteins. Numerical simulations were performed on a typical crystal, LiNbO3, and quasi-phase-matching structures for narrow-band pulses, chirped pulses, pulse trains, and multiple-wavelength pulses, which are important optical pulse shapes in vibration control of molecules and proteins, were demonstrated. We also constructed a mid-infrared multi-pulse spectroscopy system for control of protein dynamics.

Academic Significance and Societal Importance of the Research Achievements

中赤外領域にはタンパク質の構造や機能において重要な役割を果たす振動モードが多数存在する。それらのエネルギーに共鳴する中赤外光を照射することによって、人為的に構造変化や機能発現・抑止ができれば、生命科学分野の研究開発が大きく加速する。そのためには中赤外光の波形制御技術が重要となる。可視域では確立している光波形制御技術であるが、中赤外領域ではまだ未成熟である。本研究は、中赤外光の波形制御手法の新しい提案である。

Research Products

• [Journal Article] Primary photocatalytic water reduction and oxidation at an anatase TiO2 and Pt-TiO2 nanocrystalline electrode revealed by quantitative transient absorption studies (2021)
  • Author(s): Hanming Liua, Maning Liua, Ryosuke Nakamura, Yasuhiro Tachibana
  • Journal Title: Applied Catalysis B: Environmental Volume: - Pages: 120226-120226
  • DOI: 10.1016/j.apcatb.2021.120226
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Photoinduced charge carrier dynamics of metal chalcogenide semiconductor quantum dot sensitized TiO2 film for photovoltaic application (2021)
  • Author(s): Safna Ravindi Padmaperuma, Maning Liu, Ryosuke Nakamura, and Yasuhiro Tachibana
  • Journal Title: Journal of Photopolymer Science and Technology Volume: -
  • NAID: 130008119602
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Development of a Secondary Neutral Mass Spectrometer for Submicron Imaging Mass Spectrometry (2020)
  • Author(s): Yosuke Kawai, Kentaro Terada, Toshinobu Hondo, Jun Aoki, Morio Ishihara, Michisato Toyoda
  • Journal Title: JPS Conf. Proc. Volume: 31 Pages: 011065-011065
  • DOI: 10.7566/jpscp.31.011065
  • Peer Reviewed / Open Access
• [Journal Article] Polarization sensitive femtosecond mid-infrared spectrometer with tunable Fabry-Perot filter and chirped-pulse upconversion (2018)
  • Author(s): R. Nakamura, Y. Inagaki, T. Kamimura
  • Journal Title: Applied Optics Volume: 57 Issue: 36 Pages: 10517-10521
  • DOI: 10.1364/ao.57.010517
  • Peer Reviewed
• [Journal Article] Analysis of Resist Removal Phenomenon Using Laser Irradiation (2017)
  • Author(s): T. Kamimura, H. Kuramae, T. Yamashiro, K. Nuno, Y. Umeda, S. Tsujimoto, R. Nakamura, T. Nishiyama, H. Horibe
  • Journal Title: Journal of Photopolymer Science and Technology Volume: 30 Issue: 3 Pages: 291-295
  • DOI: 10.2494/photopolymer.30.291
  • NAID: 130005950263
  • ISSN: 0914-9244, 1349-6336
  • Peer Reviewed
• [Presentation] Polarization Sensitive Femtosecond Mid-Infrared Spectrometer Using Chirped-Pulse Upconversion (2018)
  • Author(s): R. Nakamura, Y. Inagaki, N. Umemura, T. Kamimura
  • Organizer: Pacific Rim Conference on Lasers and Electro-Optics (CLEO-PR)
  • Int'l Joint Research
• [Presentation] CuInS2コロイドの可視・中赤外時間分解分光 (2018)
  • Author(s): 畑寛明, 向井駿, 東本慎也, 中村亮介
  • Organizer: 第79回応用物理学会秋季学術講演会
• [Presentation] レーザー照射を用いたレジスト剥離現象の解析 (2017)
  • Author(s): 神村共住，布晃輔，山城鷹之，梅田悠史，辻本慎吾，倉前宏行，中村亮介，西山聖，堀邊英夫
  • Organizer: The 34th International Conference of Photopolymer Science and Technology
  • Int'l Joint Research / Invited