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Molecular Pathological Analysis in Salivary Duct Carcinoma from the perspective on the Development of the Personalized Treatments: A Large Multicenter Cooperative Study.

Research Project

Project/Area Number 17K08705
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Human pathology
Research InstitutionTokyo Medical University

Principal Investigator

Nagao Toshitaka  東京医科大学, 医学部, 主任教授 (90276709)

Co-Investigator(Kenkyū-buntansha) 多田 雄一郎  国際医療福祉大学, 医学部, 准教授 (70292430)
山崎 一人  帝京大学, 医学部, 教授 (60302519)
平井 秀明  東京医科大学, 医学部, 助教 (00770744)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords唾液腺癌 / バイオマーカー / 予後 / 唾液腺導管癌 / HER2 / AR / TP53 / 人体病理学 / FOXA1
Outline of Final Research Achievements

In salivary duct carcinoma (SDC), a histological analysis revealed that prominent nuclear pleomorphism, high mitoses, high poorly differentiated clusters, and vascular invasion were poor prognostic factors. Histologic risk stratification model, based on above 4 prognostically relevant parameters, could effectively predict patient survival. Immunohistochemically, low AR, p53-extreme negative/positive, low FOXA1, and high adipophilin expression were associated with poor prognosis. Furthermore, patients with SDC harboring TP53 mutations showed shorter survival rate. We categorized All SDCs into four main subtypes pursuant to a combination of the expression of AR, HER2, and Ki-67. Consequently, patients with ‘apocrine A’ displayed a better progression-free survival than those with any other subtypes. Based on this classification, we conducted phase II trial of anti-AR and HER2 therapies in patients with AR- and HER2-positive SDCs. These therapies demonstrated high efficacy.

Academic Significance and Societal Importance of the Research Achievements

唾液腺導管癌(SDC)は比較的稀な組織型のため少数例での検討しかされておらず、本研究のような大規模なSDCの解析は世界的にも類を見ない。SDCの各種バイオマーカーの発現様式や遺伝子異常と臨床病理学的特徴との関連を明らかにすることで、実臨床において正確な予後予測や適切な治療法選択に寄与すると考えられる。また、我々が行ったSDCに対する複合アンドロゲン遮断療法と抗HER2療法は共に、世界初の前向き臨床試験であり、その成果は米国NCCNガイドライン最新版に反映されている。これはSDCに対する個別化治療を確立し、当該患者の予後やQOLの改善に繋がる成果であり、大変意義深い。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (133 results)

All 2020 2019 2018 2017

All Journal Article (59 results) (of which Int'l Joint Research: 7 results,  Peer Reviewed: 55 results,  Open Access: 30 results) Presentation (68 results) (of which Int'l Joint Research: 2 results,  Invited: 26 results) Book (6 results)

  • [Journal Article] Salivary duct carcinoma: Updates in histology, cytology, molecular biology, and treatment2020

    • Author(s)
      Nakaguro Masato、Tada Yuichiro、Faquin William C.、Sadow Peter M.、Wirth Lori J.、Nagao Toshitaka
    • Journal Title

      Cancer Cytopathology

      Volume: - Issue: 10 Pages: 693-703

    • DOI

      10.1002/cncy.22288

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Giant cell arteritis in a patient with aortic dissection: a case report2020

    • Author(s)
      Obikane Hiyo、Fujiyoshi Toshiki、Takahashi Satoshi、Ogino Hitoshi、Matsubayashi Jun、Nagao Toshitaka、Ishibashi-Ueda Hatsue
    • Journal Title

      Cardiovascular Pathology

      Volume: 46 Pages: 107206-107206

    • DOI

      10.1016/j.carpath.2020.107206

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cytology Reporting System for Lung Cancer from the Japan Lung Cancer Society and Japanese Society of Clinical Cytology: An Interobserver Reproducibility Study and Risk of Malignancy Evaluation on Cytology Specimens2020

    • Author(s)
      Hiroshima K、Yoshizawa A、Takenaka A、Haba R、Kawahara K、Minami Y、Kakinuma H、Shibuki Y、Miyake Si、Kajio K、Miyamoto K、Nagatomo M、Nishimura S、Mano Mi、Matsubayashi J、Motoi N、Nagao T、Nakatsuka S、Yoshida T、Satoh Y
    • Journal Title

      Acta Cytologica

      Volume: - Issue: 5 Pages: 1-11

    • DOI

      10.1159/000506431

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The significance of micro-lymphatic invasion and pathological Gleason score in prostate cancer patients with pathologically organ-confined disease and negative surgical margins after robot-assisted radical prostatectomy2020

    • Author(s)
      Hashimoto Takeshi, Nagao Toshitaka, et al
    • Journal Title

      Int J Clin Oncol

      Volume: 25

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neck dissection prolongs survival in patient with stage IVC hypopharyngeal carcinoma with mixed responses to nivolumab2020

    • Author(s)
      Ito Tatsuya, Nagao Toshitaka, et al
    • Journal Title

      Auris Nasus Larynx

      Volume: -

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Salvage carbon ion radiotherapy for recurrent solitary fibrous tumor: A case report and literature review2020

    • Author(s)
      Murata Kazuma、Endo Kenji、Aihara Takato、Matsuoka Yuji、Nishimura Hirosuke、Suzuki Hidekazu、Sawaji Yasunobu、Yamamoto Kengo、Fukami Shinjiro、Tanigawa Maki、Matsubayashi Jun、Nagao Toshitaka、Imai Reiko
    • Journal Title

      Journal of Orthopaedic Surgery

      Volume: 28 Issue: 1 Pages: 1-7

    • DOI

      10.1177/2309499019896099

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The clinicopathological significance of the adipophilin and fatty acid synthase expression in salivary duct carcinoma2020

    • Author(s)
      Hirai Hideaki, Tada Yuichiro, Nagao Toshiitaka, et al.
    • Journal Title

      Virchows Arch

      Volume: -

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Central pathology review of salivary gland adenoid cystic carcinoma2020

    • Author(s)
      Ueda K、Murase T、Nagao T、Kusafuka K、Urano M、Yamamoto H、Nakaguro M、Taguchi K、Masaki A、Hirai H、Kawakita D、Tsukahara K、Hato N、Nagao T、Fujimoto Y、Sakurai K、Hanai N、Kano S、Onitsuka T、Okami K、Nibu K、Tada Y、Kawata R、Inagaki H
    • Journal Title

      Head & Neck

      Volume: X Issue: 8 Pages: 1721-1727

    • DOI

      10.1002/hed.26081

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic Implication of Histopathologic Indicators in Salivary Duct Carcinoma2020

    • Author(s)
      Nakaguro Masato、Sato Yukiko、Tada Yuichiro、Kawakita Daisuke、Nagao Toshitaka et al.
    • Journal Title

      The American Journal of Surgical Pathology

      Volume: 44 Issue: 4 Pages: 526-535

    • DOI

      10.1097/pas.0000000000001413

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Histopathological evaluation of minor salivary gland papillary-cystic tumours: focus on genetic alterations in sialadenoma papilliferum and intraductal papillary mucinous neoplasm2019

    • Author(s)
      Nakaguro Masato、Urano Makoto、Ogawa Ikuko、Hirai Hideaki、Yamamoto Yoshinari、Yamaguchi Hiroshi、Tanigawa Maki、Matsubayashi Jun、Hirano Hiroshi、Shibahara Junji、Tada Yuichiro、Tsuzuki Toyonori、Okada Yasuo、Sato Yuichiro、Ikeda Kenichiro、Sukeda Aoi、Honda Yumi、Mikami Yoshiki、Nagao Toshitaka
    • Journal Title

      Histopathology

      Volume: 76 Issue: 3 Pages: 411-422

    • DOI

      10.1111/his.13990

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Palatal Polymorphous Adenocarcinoma with High-Grade Transformation: A Case Report and Literature Review2019

    • Author(s)
      Kikuchi Kentaro, Nagao Toshitaka、et al
    • Journal Title

      Head Neck Pathol

      Volume: 13

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A case of primary clear cell hepatocellular carcinoma comprised mostly of clear cells2019

    • Author(s)
      Kokubo Reiji、Saito Kazuhiro、Shirota Natsuhiko、Wakabayashi Yukari、Tsuchida Akihiko、Nagai Takeshi、Nagao Toshitaka
    • Journal Title

      Radiology Case Reports

      Volume: 14 Issue: 11 Pages: 1377-1381

    • DOI

      10.1016/j.radcr.2019.08.021

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Keratocystoma of the parotid gland2019

    • Author(s)
      Komatsu Hirokazu、Kumoi Kazuo、Inokuchi Go、Hashimoto Kimio、Nagao Toshitaka、Otsuki Naoki、Nibu Ken-ichi
    • Journal Title

      Auris Nasus Larynx

      Volume: - Issue: 3 Pages: 481-484

    • DOI

      10.1016/j.anl.2019.05.006

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and pathological predictors of recurrence in breast cancer patients achieving pathological complete response to neoadjuvant chemotherapy2019

    • Author(s)
      Asaoka Mariko、Narui Kazutaka、Suganuma Nobuyasu、Chishima Takashi、Yamada Akimitsu、Sugae Sadatoshi、Kawai Saori、Uenaka Natsuki、Teraoka Saeko、Miyahara Kana、Kawate Takahiko、Sato Eichi、Nagao Toshitaka、Matsubara Yuka、Gandhi Shipra、Takabe Kazuaki、Ishikawa Takashi
    • Journal Title

      European Journal of Surgical Oncology

      Volume: 45 Issue: 12 Pages: 2289-2294

    • DOI

      10.1016/j.ejso.2019.08.001

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] First autopsy analysis of the efficacy of intra-operative additional photodynamic therapy for patients with glioblastoma2019

    • Author(s)
      Akimoto Jiro, Nagao Toshitaka、et al
    • Journal Title

      Brain Tumor Pathol

      Volume: 36

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A New Method for Diagnosing Biochemical Abnormalities of Anterior Cruciate Ligament (ACL) in Human Knees: A Raman Spectroscopic Study2019

    • Author(s)
      Matsunaga R, Takahashi Y, Takahashi RH, Nagao T, Shishido T, Tateiwa T, Pezzotti G, Yamamoto K.
    • Journal Title

      Acta Biomaterialia

      Volume: 99 Pages: 284-294

    • DOI

      10.1016/j.actbio.2019.09.016

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Carboplatin and Docetaxel in Patients With Salivary Gland Carcinoma: A Retrospective Study2019

    • Author(s)
      OKADA TAKURO、SAOTOME TAKASHI、NAGAO TOSHITAKA、MASUBUCHI TATSUO、FUSHIMI CHIHIRO、MATSUKI TAKASHI、TAKAHASHI HIDEAKI、MIURA KOUKI、TSUKAHARA KIYOAKI、TADA YUICHIRO
    • Journal Title

      In Vivo

      Volume: 33 Issue: 3 Pages: 843-853

    • DOI

      10.21873/invivo.11549

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Diagnostic Significance of HRAS Mutations in Epithelial-Myoepithelial Carcinomas Exhibiting a Broad Histopathologic Spectrum2019

    • Author(s)
      Urano Makoto、Nakaguro Masato、Yamamoto Yoshinari、Hirai Hideaki、Tanigawa Maki、Saigusa Natsuki、Shimizu Akira、Tsukahara Kiyoaki、Tada Yuichiro、Sakurai Kouhei、Isomura Madoka、Okumura Yuki、Yamaguchi Hiroshi、Matsubayashi Jun、Nagao Toshitaka
    • Journal Title

      The American Journal of Surgical Pathology

      Volume: 印刷中 Issue: 7 Pages: 984-994

    • DOI

      10.1097/pas.0000000000001258

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Performance of Oncomine Fusion Transcript kit for formalin‐fixed, paraffin‐embedded lung cancer specimens2019

    • Author(s)
      Sakai Kazuko、Ohira Tatsuo、Matsubayashi Jun、Yoneshige Azusa、Ito Akihiko、Mitsudomi Tetsuya、Nagao Toshitaka、Iwamatsu Emi、Katayama Jin、Ikeda Norihiko、Nishio Kazuto
    • Journal Title

      Cancer Science

      Volume: 印刷中 Issue: 6 Pages: 2044-2049

    • DOI

      10.1111/cas.14016

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cytological differences between invasive and noninvasive or minimally invasive lung adenocarcinomas diagnosed in Japanese patients using needle biopsy specimens of pulmonary lesions <3 cm in diameter2019

    • Author(s)
      Matsubayashi Jun、Miyake Shinji、Kudo Yujin、Shimada Yoshihisa、Maeda Junichi、Saji Hisashi、Kakihana Masatoshi、Park Jinho、Kajiwara Naohiro、Inoue Shigeru、Saito Kazuhiro、Ohira Tatsuo、Ikeda Norihiko、Tokuuye Koichi、Nagao Toshitaka
    • Journal Title

      Diagnostic Cytopathology

      Volume: 印刷中 Issue: 7 Pages: 688-694

    • DOI

      10.1002/dc.24171

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Adenoid cystic carcinoma with high-grade transformation forming spindle cell component of the submandibular gland2019

    • Author(s)
      Miyazaki Masaru、Aoki Mikiko、Koga Kaori、Hamasaki Makoto、Sugiyama Yoshikazu、Midorikawa Kensuke、Hamatake Daisuke、Masaki Michio、Takamatsu Yasushi、Iwasaki Akinori、Sakata Toshifumi、Nagao Toshitaka、Nabeshima Kazuki
    • Journal Title

      Auris Nasus Larynx

      Volume: 印刷中 Issue: 6 Pages: 934-939

    • DOI

      10.1016/j.anl.2019.01.014

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Familial Case of a Whole Germline CDC73 Deletion Discordant for Primary Hyperparathyroidism2019

    • Author(s)
      Hatabu Naomi、Katori Naho、Sato Takeshi、Maeda Naonori、Suzuki Eri、Komiyama Osamu、Tsutsui Hidemitsu、Nagao Toshitaka、Nakauchi-Takahashi Hana、Matsunaga Tatsuo、Ishii Tomohiro、Hasegawa Tomonobu、Yamazawa Kazuki
    • Journal Title

      Hormone Research in Paediatrics

      Volume: 印刷中 Issue: 1 Pages: 1-8

    • DOI

      10.1159/000495800

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Difference in immunohistochemical characteristics between Takayasu arteritis and giant cell arteritis: It may be better to distinguish them in the same age2019

    • Author(s)
      Kurata Atsushi、Saito Akira、Hashimoto Hirotsugu、Fujita Koji、Ohno Shin-ichiro、Kamma Hiroshi、Nagao Toshitaka、Kobayashi Shigeto、Yamashina Akira、Kuroda Masahiko
    • Journal Title

      Modern Rheumatology

      Volume: 印刷中 Issue: 6 Pages: 1-10

    • DOI

      10.1080/14397595.2019.1570999

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prognostic significance of the presence of tertiary Gleason grade 5 in robot-assisted radical prostatectomy specimens in Japanese patients with clinically localized prostate cancer2019

    • Author(s)
      Kamoda Naohiro、Ohori Makoto、Hirasawa Yosuke、Inoue Rie、Hashimoto Takeshi、Satake Naoya、Gondo Tatsuo、Nakagami Yoshihiro、Nagao Toshitaka、Ohno Yoshio
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 49 Issue: 3 Pages: 276-280

    • DOI

      10.1093/jjco/hyy194

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Data Set for the Reporting of Carcinomas of the Major Salivary Glands: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting2019

    • Author(s)
      Seethala Raja R.、Altemani Albina、Ferris Robert L.、Fonseca Isabel、Gnepp Douglas R.、Ha Patrick、Nagao Toshitaka、Skalova Alena、Stenman G?ran、Thompson Lester D. R.
    • Journal Title

      Archives of Pathology & Laboratory Medicine

      Volume: 143 Issue: 5 Pages: 578-586

    • DOI

      10.5858/arpa.2018-0422-sa

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Phase II Trial of Trastuzumab and Docetaxel in Patients With Human Epidermal Growth Factor Receptor 2 Positive Salivary Duct Carcinoma2019

    • Author(s)
      Takahashi Hideaki、Tada Yuichiro、Saotome Takashi、Akazawa Kohei、Ojiri Hiroya、Fushimi Chihiro、Masubuchi Tatsuo、Matsuki Takashi、Tani Kaori、Osamura Robert Y.、Hirai Hideaki、Yamada Shuhei、Kawakita Daisuke、Miura Kouki、Kamata Shin-etsu、Nagao Toshitaka
    • Journal Title

      Journal of Clinical Oncology

      Volume: 37 Issue: 2 Pages: 125-134

    • DOI

      10.1200/jco.18.00545

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fascin as a Useful Marker for Identifying Neural Components in Immature Teratomas of Human Ovary and Those Derived From Murine Embryonic Stem Cells2018

    • Author(s)
      Umehara R, Kurata A, Takanashi M, Hashimoto H, Fujita K, Nagao T, Kuroda M.
    • Journal Title

      Int J Gynecol Pathol.

      Volume: - Issue: 4 Pages: 1-9

    • DOI

      10.1097/pgp.0000000000000528

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ezh2 loss propagates hypermethylation at T cell differentiation?regulating genes to promote leukemic transformation2018

    • Author(s)
      Wang Changshan、Oshima Motohiko、Sato Daisuke、Matsui Hirotaka、Kubota Sho、Aoyama Kazumasa、Nakajima-Takagi Yaeko、Koide Shuhei、Matsubayashi Jun、Mochizuki-Kashio Makiko、Nakano-Yokomizo Takako、Bai Jie、Nagao Toshitaka、Kanai Akinori、Iwama Atsushi、Sashida Goro
    • Journal Title

      Journal of Clinical Investigation

      Volume: 128 Issue: 9 Pages: 3872-3886

    • DOI

      10.1172/jci94645

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The high expression of FOXA1 is correlated with a favourable prognosis in salivary duct carcinomas: a study of 142 cases2018

    • Author(s)
      Urano Makoto、Hirai Hideaki、Tada Yuichiro、Otsuka Kuninori、Watanabe Yoshihiro、Sakai Akihiro、Ebisumoto Koji、Togashi Takafumi、Ueki Yushi、Ota Hisayuki、Sato Yukiko、Saigusa Natsuki、Nakaguro Masato、Hanazawa Toyoyuki、Nagao Toshitaka
    • Journal Title

      Histopathology

      Volume: 73 Issue: 6 Pages: 943-952

    • DOI

      10.1111/his.13706

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Thermal effects of the Thunderbeat device on the recurrent laryngeal nerve during thyroid surgery2018

    • Author(s)
      Tamura Atsumi、Tsutsui Hidemitsu、Yano Yukiko、Ohara Ryoji、Hoshi Masae、Nagai Takeshi、Nagao Toshitaka、Ikeda Norihiko
    • Journal Title

      Surgery Today

      Volume: 48 Issue: 12 Pages: 1076-1080

    • DOI

      10.1007/s00595-018-1692-1

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 唾液腺腺房細胞癌の再検討により発見された分泌癌の3例2018

    • Author(s)
      片岡 俊朗, 加藤 生真, 山中 正二, 折舘 伸彦, 長尾 俊孝, 大橋 健一
    • Journal Title

      診断病理

      Volume: 35 Pages: 118-123

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] A case of secretory carcinoma of the parotid gland provides cytological clues for the differential diagnosis of this disease2018

    • Author(s)
      Ohta Y.、Norose T.、Ohike N.、Takiguchi S.、Murayama M.、Kobayashi S.、Shiokawa A.、Nagao T.
    • Journal Title

      Cytopathology

      Volume: 印刷中 Issue: 4 Pages: 375-379

    • DOI

      10.1111/cyt.12548

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Prognostic factors for surgically resected non-small cell lung cancer with cavity formation2018

    • Author(s)
      Shigefuku Shunsuke、Kudo Yujin、Yunaiyama Daisuke、Matsubayashi Jun、Park Jinho、Nagao Toshitaka、Shimada Yoshihisa、Saji Hisashi、Hagiwara Masaru、Okano Tetsuya、Kakihana Masatoshi、Kajiwara Naohiro、Ohira Tatsuo、Ikeda Norihiko
    • Journal Title

      Journal of Thoracic Disease

      Volume: 10 Issue: 2 Pages: 973-983

    • DOI

      10.21037/jtd.2018.01.61

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Granulocyte colony stimulating factor-producing lung cancer with severe anemia of inflammation2018

    • Author(s)
      Murakami Koutaro、Kudo Yujin、Kakihana Masatoshi、Matsubayashi Jun、Okano Tetsuya、Shimada Yoshihisa、Nagao Toshitaka、Kajiwara Naohiro、Ohira Tatsuo、Ikeda Norihiko
    • Journal Title

      General Thoracic and Cardiovascular Surgery

      Volume: 印刷中 Issue: 7 Pages: 415-418

    • DOI

      10.1007/s11748-018-0914-1

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Palatal Polymorphous Adenocarcinoma with High-Grade Transformation: A Case Report and Literature Review2018

    • Author(s)
      Kikuchi Kentaro、Nagao Toshitaka、Ide Fumio、Takizawa Shota、Sakashita Hideaki、Tsujino Ichiro、Li Tie-Jun、Kusama Kaoru
    • Journal Title

      Head and Neck Pathology

      Volume: 印刷中 Issue: 2 Pages: 131-139

    • DOI

      10.1007/s12105-018-0916-4

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Low-Grade Intraductal Carcinoma of the Salivary Gland with Prominent Oncocytic Change: A Newly Described Variant2018

    • Author(s)
      Nakaguro Masato、Urano Makoto、Suzuki Hiroaki、Yamada Kazuyuki、Sakaguchi Asumi、Ogura Kanako、Matsumoto Toshiharu、Ono Noritsugu、Asato Tsuguharu、Mikami Yoshiki、Imai Hiroshi、Nagao Toshitaka
    • Journal Title

      Histopathology

      Volume: 印刷中 Issue: 2 Pages: 314-320

    • DOI

      10.1111/his.13517

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pathologic Findings and Clinical Course of Midline Paraventricular Gliomas Diagnosed Using a Neuroendoscope2018

    • Author(s)
      Fukami Shinjiro、Nakajima Nobuyuki、Okada Hirofumi、Akimoto Jiro、Miki Tamotsu、Fukuhara Hirokazu、Shishido-Hara Yukiko、Nagao Toshitaka、Tsuda Masumi、Kohno Michihiro
    • Journal Title

      World Neurosurgery

      Volume: - Pages: e366-e377

    • DOI

      10.1016/j.wneu.2018.02.185

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Intraepithelial CD8+ lymphocytes as a predictive diagnostic biomarker for the remission of oral lichen planus2018

    • Author(s)
      Enomoto Ai、Sato Eiichi、Yasuda Takashi、Isomura Tatsuya、Nagao Toshitaka、Chikazu Daichi
    • Journal Title

      Human Pathology

      Volume: 74 Pages: 43-53

    • DOI

      10.1016/j.humpath.2017.12.008

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Fascin as a useful marker for identifying neural components in immature teratomas of human ovary and those derived from murine embryonic stem cells2018

    • Author(s)
      Umehara R, Kurata A, Takanashi M, Hashimoto H, Fujita K, Nagao T, Kuroda M
    • Journal Title

      Int J Gynecol Pathol

      Volume: 印刷中

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hemorrhage of MRI and immunohistochemical panels distinguish secretory carcinoma from acinic cell carcinoma2018

    • Author(s)
      Kuwabara H, Yamamoto K, Terada T, Nagao T, Kawata R, Hirose Y
    • Journal Title

      Laryngoscope Investig Otolaryngol

      Volume: 印刷中

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 【頭頸部腫瘍I】 唾液腺腫瘍 唾液腺腫瘍2017WHO分類改訂のポイント2018

    • Author(s)
      長尾 俊孝
    • Journal Title

      病理と臨床

      Volume: 36 Pages: 216-222

    • Related Report
      2017 Research-status Report
  • [Journal Article] Prognostic and histogenetic roles of gene alteration and the expression of key potentially actionable targets in salivary duct carcinomas2017

    • Author(s)
      Shimura Tomotaka、Tada Yuichiro、Hirai Hideaki、Sato Yukiko、et al.
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 2 Pages: 1852-1867

    • DOI

      10.18632/oncotarget.22927

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] High-grade transformation/dedifferentiation of an adenoid cystic carcinoma of the minor salivary gland to myoepithelial carcinoma2017

    • Author(s)
      Tando So、Nagao Toshitaka、Kayano Kaori、Fushiki Shinji、Itoh Kyoko
    • Journal Title

      Pathology International

      Volume: 68 Issue: 2 Pages: 133-138

    • DOI

      10.1111/pin.12624

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] A prospective phase II study of combined androgen blockade in patients with androgen receptor-positive metastatic or locally advanced unresectable salivary gland carcinoma2017

    • Author(s)
      Fushimi C、Tada Y、Takahashi H、Nagao T、Ojiri H、Masubuchi T、Matsuki T、Miura K、Kawakita D、Hirai H、Hoshino E、Kamata S、Saotome T
    • Journal Title

      Annals of Oncology

      Volume: 29 Issue: 4 Pages: 979-984

    • DOI

      10.1093/annonc/mdx771

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Biomarker immunoprofile in salivary duct carcinomas: clinicopathological and prognostic implications with evaluation of the revised classification2017

    • Author(s)
      Takase Soichiro、Kano Satoshi、Tada Yuichiro、Sato Yukiko、et al.
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 35 Pages: 59023-59035

    • DOI

      10.18632/oncotarget.19812

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prediction of high-stage liver fibrosis using ADC value on diffusion-weighted imaging and quantitative enhancement ratio at the hepatobiliary phase of Gd-EOB-DTPA?enhanced MRI at 1.5?T2017

    • Author(s)
      Harada Taiyo L、Saito Kazuhiro、Araki Yoichi、Matsubayashi Jun、Nagao Toshitaka、Sugimoto Katsutoshi、Tokuuye Koichi
    • Journal Title

      Acta Radiologica

      Volume: 59 Issue: 5 Pages: 509-516

    • DOI

      10.1177/0284185117725778

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Establishment and characterization of a clear cell odontogenic carcinoma cell line with EWSR1-ATF1 fusion gene.2017

    • Author(s)
      Kujiraoka S, Tsunematsu T, Sato Y, Yoshida M, Tohyama R, Tanaka M, Kobayashi Y, Kondo T, Ushio A, Otsuka K, Kurosawa M, Saito M. Yamada A, Arakaki R, Nagai H, Nikai H, Takeuchi K, Nagao T, Miyamoto Y, Ishimaru N, Kudo Y.
    • Journal Title

      Oral Oncol.

      Volume: 69 Pages: 46-55

    • DOI

      10.1016/j.oraloncology.2017.04.003

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prognostic factors of adenoid cystic carcinoma of the head and neck in carbon-ion radiotherapy: The impact of histological subtypes2017

    • Author(s)
      Ikawa Hiroaki、Koto Masashi、Takagi Ryo、Ebner Daniel K.、Hasegawa Azusa、Naganawa Kensuke、Takenouchi Toshinao、Nagao Toshitaka、Nomura Takeshi、Shibahara Takahiko、Tsuji Hiroshi、Kamada Tadashi
    • Journal Title

      Radiotherapy and Oncology

      Volume: 123 Issue: 3 Pages: 387-393

    • DOI

      10.1016/j.radonc.2017.04.026

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] A selected reaction monitoring mass spectrometric assessment of biomarker candidates diagnosing large-cell neuroendocrine lung carcinoma by the scaling method using endogenous references2017

    • Author(s)
      Fukuda Tetsuya、Nomura Masaharu、Kato Yasufumi、Tojo Hiromasa、Fujii Kiyonaga、Nagao Toshitaka、Bando Yasuhiko、Fehniger Thomas E.、Marko-Varga Gy?rgy、Nakamura Haruhiko、Kato Harubumi、Nishimura Toshihide
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 4 Pages: e0176219-e0176219

    • DOI

      10.1371/journal.pone.0176219

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Immunophenotypic profiles for distinguishing orbital mucosa-associated lymphoid tissue lymphoma from benign lymphoproliferative tumors2017

    • Author(s)
      Ueda Shunichiro、Usui Yoshihiko、Nagai Takeshi、Diaz-Aguilar Daniel、Nagao Toshitaka、Goto Hiroshi
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 61 Issue: 4 Pages: 354-360

    • DOI

      10.1007/s10384-017-0513-1

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Mucoepidermoid carcinoma with extensive spindled morphology and melanocytic marker expression2017

    • Author(s)
      Oide Takashi、Hiroshima Kenzo、Takahashi Yoko、Fugo Kazunori、Yamatoji Masanobu、Kasamatsu Atsushi、Endo-Sakamoto Yosuke、Shiiba Masashi、Uzawa Katsuhiro、Tanzawa Hideki、Nagao Toshitaka、Nakatani Yukio
    • Journal Title

      Human Pathology

      Volume: 67 Pages: 181-186

    • DOI

      10.1016/j.humpath.2017.03.010

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Japanese Clinical Practice Guideline for Head and Neck Cancer2017

    • Author(s)
      Nibu Ken-ichi、Hayashi Ryuichi、Asakage Takahiro、Nagao Toshitaka、Nakatsuka Takashi
    • Journal Title

      Auris Nasus Larynx

      Volume: 44 Issue: 4 Pages: 375-380

    • DOI

      10.1016/j.anl.2017.02.004

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Vascular Smooth Muscle Cell Maturation Stage and Ki-67 Index are Diagnostic Biomarkers for Pathologic Grade of Ovarian Teratoma.2017

    • Author(s)
      Hongo-Kohama M, Kurata A, Hashimoto H, Fujita K, Horiuchi H, Nagao T, Kuroda M.
    • Journal Title

      Int J Gynecol Pathol.

      Volume: ahead of print Issue: 6 Pages: 582-592

    • DOI

      10.1097/pgp.0000000000000373

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Sonographic classification of testicular tumors by tissue harmonic imaging: experience of 58 cases2017

    • Author(s)
      Kawamoto Atsuo、Hatano Tadashi、Saito Kazuhiro、Inoue Rie、Nagao Toshitaka、Sanada Shigeru
    • Journal Title

      Journal of Medical Ultrasonics

      Volume: 45 Issue: 1 Pages: 103-111

    • DOI

      10.1007/s10396-017-0783-8

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease.2017

    • Author(s)
      Takahashi RH, Nagao T, Gouras GK
    • Journal Title

      Pathol Int

      Volume: 67 Issue: 4 Pages: 185-193

    • DOI

      10.1111/pin.12520

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 肺血栓塞栓症が疑われた肺動脈内膜肉腫の1例2017

    • Author(s)
      河口 洋平, 岡野 哲也, 垣花 昌俊, 梶原 直央, 大平 達夫, 丸野 恵大, 小泉 信達, 荻野 均, 平井 秀明, 帯包 妃代, 長尾 俊孝, 池田 徳彦, 仁木 利郎
    • Journal Title

      肺癌

      Volume: 57 Pages: 875-876

    • NAID

      130006307480

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 唾液腺病理の新展開2017

    • Author(s)
      長尾 俊孝
    • Journal Title

      耳鼻と臨床

      Volume: 63

    • NAID

      130007535772

    • Related Report
      2017 Research-status Report
  • [Journal Article] 【頭頸部悪性腫瘍の疑問に答える】 病因・病態理解 唾液腺腫瘍の組織像が多彩な理由を教えてください2017

    • Author(s)
      谷川 真希, 長尾 俊孝
    • Journal Title

      JOHNS

      Volume: 9 Pages: 1089-1091

    • Related Report
      2017 Research-status Report
  • [Journal Article] 【病理診断に直結した組織学】 頭頸部 大唾液腺2017

    • Author(s)
      谷川 真希, 山科 光正, 長尾 俊孝
    • Journal Title

      病理と臨床

      Volume: 35 Pages: 123-135

    • Related Report
      2017 Research-status Report
  • [Presentation] 経口プレドニゾロンが著効した腎サルコイドーシスの1例2020

    • Author(s)
      永井 麻梨恵、長尾 俊孝他
    • Organizer
      第655回日本内科学会関東地方会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 類内膜型の形態・発現を示す低異型度子宮頸部腺癌の一例2020

    • Author(s)
      本多 将吾、長尾 俊孝他
    • Organizer
      第51回日本婦人科病理学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 唾液腺腫瘍の病理と細胞診2020

    • Author(s)
      長尾 俊孝
    • Organizer
      第34回 宮城県臨床細胞学会学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 唾液腺腫瘍のおさえておきたい病理と細胞診2020

    • Author(s)
      長尾 俊孝
    • Organizer
      第24回 神奈川県細胞検査士会学術研修会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Prognostic factors for surgically resected non-small cell lung cancer2019

    • Author(s)
      Shigefuku S, Kudo Y, Yunaiyama D, Matsubayashi J, Park J, Nagao T, Shimada Y, Kajiwara N, Ohira T, Ikeda N
    • Organizer
      The 65th Annual Congress of International College of surgeons Japan Section
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The Role of Quantitative Metabolic Metrics on FDG-PET/CT in predicting pathological Invasive Factors in cN0 Lung Adenocarcinoma2019

    • Author(s)
      田中 健彦、長尾 俊孝他
    • Organizer
      第183回東京医科大学医学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 血管周囲リンパ球浸潤と脱髄・軸索崩壊を示した、中枢神経系の炎症性疾患2症例の病理学的検討2019

    • Author(s)
      大原 万理恵、長尾 俊孝他
    • Organizer
      第108回日本病理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 高悪性度成分が主体であった乳腺相似分泌癌の一例2019

    • Author(s)
      浅井 沙月、長尾 俊孝他
    • Organizer
      第108回日本病理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 急性肝炎に伴う急性腎障害に対し、血漿交換療法で治療したBile cast nephropathyの一例2019

    • Author(s)
      荒井 誠大、長尾 俊孝他
    • Organizer
      第64回日本透析医学会学術集会・総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 非典型溶血性尿毒症症候群(aHUS)を呈し、血漿交換・エクリズマブ投与を行うも透析に至った一例2019

    • Author(s)
      齋藤 優、長尾 俊孝他
    • Organizer
      第64回日本透析医学会学術集会・総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 当院におけるEGFR遺伝子変異検査に対するLiquid BiopsyとTissue Biopsyの現状2019

    • Author(s)
      工藤 勇人、長尾 俊孝他
    • Organizer
      第42回日本呼吸器内視鏡学会学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 当院における進行・再発非小細胞肺癌に対する気管支鏡検体を用いたPD-L1検査の現状2019

    • Author(s)
      田中 裕紀、長尾 俊孝他
    • Organizer
      第42回日本呼吸器内視鏡学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 血清抗p53抗体強陽性を示した若年発症の食道胃接合部癌の1例2019

    • Author(s)
      河合 優佑、長尾 俊孝他
    • Organizer
      日本消化器病学会関東支部第355回例会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 診断に針生検が有用であった黄色肉芽腫性腫瘤の1例2019

    • Author(s)
      菊地 美穂、長尾 俊孝他
    • Organizer
      第356回日本消化器病学会関東支部例会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 肺癌細胞診の可能性-鑑別と限界- 扁平上皮癌の鑑別と限界2019

    • Author(s)
      三宅 真司、長尾 俊孝他
    • Organizer
      第58回日本臨床細胞学会秋季大会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 新たな肺癌細胞診判定区分の提案2019

    • Author(s)
      廣島 健三、長尾 俊孝他
    • Organizer
      第60回日本肺癌学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 唾液腺癌の病理診断:その実際と新たな展開2019

    • Author(s)
      長尾 俊孝
    • Organizer
      第50回日本病理学会関東支部・千葉地区集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 嚢胞を有する耳下腺腫瘍の1例2019

    • Author(s)
      鳥山 茜、長尾 俊孝他
    • Organizer
      第50回日本病理学会関東支部・千葉地区集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 胸腺カルチノイドの細胞学的検討2019

    • Author(s)
      秋山 里佳子、長尾 俊孝他
    • Organizer
      第58回日本臨床細胞学会秋期大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] The immune checkpoint inhibitor expression and tumor microenvironment in salivary duct carci-nomas2019

    • Author(s)
      三枝 奈津季、長尾 俊孝他
    • Organizer
      第184回東京医科大学医学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 唾液腺癌に対するカルボプラチン、ドセタキセル併用療法に関する後方視的研究2019

    • Author(s)
      岡田 拓朗、長尾 俊孝他
    • Organizer
      第184回東京医科大学医学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 上顎歯肉から発生した多形腺腫由来上皮筋上皮癌の一例2019

    • Author(s)
      鈴木 佳苗、長尾 俊孝他
    • Organizer
      第58回日本臨床細胞学会秋期大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Warthin-like mucoepidermoid carcinomaの1例2019

    • Author(s)
      山田 恭子、長尾 俊孝他
    • Organizer
      第58回日本臨床細胞学会秋期大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 唾液腺導管癌における脂質関連蛋白発現の臨床病理学的意義2019

    • Author(s)
      平井 秀明、長尾 俊孝他
    • Organizer
      第64回日本唾液腺学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 甲状腺・唾液腺疾患の病理2019

    • Author(s)
      長尾 俊孝
    • Organizer
      第87回日本病理学会近畿支部学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 術後再発を来たした食道癌肉腫の一例2019

    • Author(s)
      菊地 美穂、長尾 俊孝他
    • Organizer
      第353回日本消化器病学会 関東支部例会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 唾液腺導管癌ではadipophilinの発現が予後不良因子となりうる2019

    • Author(s)
      平井 秀明、長尾 俊孝他
    • Organizer
      第108回日本病理学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 非小細胞肺癌根治切除例における再発後の外科的治療の現状(英語)2019

    • Author(s)
      工藤 勇人、長尾 俊孝他
    • Organizer
      第36回日本呼吸器外科学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 口腔扁平苔癬における上皮内へのCD8(+)リンパ球浸潤は寛解の予測因子となりうる2019

    • Author(s)
      榎本 愛、長尾 俊孝他
    • Organizer
      第108回日本病理学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] グリコーゲン含有による明細胞化を伴った唾液腺オンコサイトーマの一例2019

    • Author(s)
      横田 章、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
  • [Presentation] 体腔液の細胞診の進化 術中胸腔洗浄細胞診に出現する細胞像の特徴2019

    • Author(s)
      垣花 昌俊、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 肺癌治療と細胞診の活用 肺癌の治療における細胞診断の役割 総論的な立場で2019

    • Author(s)
      松林 純、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 唾液腺細胞診ミラノシステム-症例を通じてミラノシステムを体験する- 唾液腺穿刺吸引細胞診のミラノシステムを用いた症例検討2019

    • Author(s)
      谷川 真希、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 胸腺原発MALTリンパ腫2例の細胞学的検討2019

    • Author(s)
      山本 善也、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
  • [Presentation] 術中迅速診断で腺癌との鑑別に苦慮した硬化性肺胞上皮腫の2例2019

    • Author(s)
      忽滑谷 昌平、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
  • [Presentation] 肺癌細胞診の判定基準:新たな肺癌診療の時代に向けて JSCC-JLCSによる新たな判定基準の提案2019

    • Author(s)
      廣島 健三、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 肺癌に対するLiquid-based cytology検体を用いた遺伝子検査2019

    • Author(s)
      大平 達夫、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 耳下腺原発神経内分泌腫瘍の一例2019

    • Author(s)
      武田 奈津子、長尾 俊孝他
    • Organizer
      第60回日本臨床細胞学会総会(春期大会)
    • Related Report
      2019 Annual Research Report
  • [Presentation] 唾液腺腫瘍の細胞診と病理診断2019

    • Author(s)
      長尾 俊孝
    • Organizer
      第33回関東臨床細胞学会学術集会、第38回東京都臨床細胞学会総会・学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 肺原発上皮筋上皮癌の1例2018

    • Author(s)
      山口 真由実, 松林 純, 三宅 真司, 石原 里佳子, 忽滑谷 昌平, 山科 光正, 谷川 真希, 垣花 昌俊, 大平 達夫, 池田 徳彦, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 唾液腺細胞診ミラノシステムの実際の運用と問題点 唾液腺穿刺吸引細胞診の新たな報告様式の有用性2018

    • Author(s)
      谷川 真希, 三宅 真司, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 症例から学ぶ唾液腺穿刺吸引細胞診の基本 唾液腺多形腺腫の細胞判定2018

    • Author(s)
      稲垣 敦史, 三宅 真司, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 唾液腺腫瘍の病理と細胞診断2018

    • Author(s)
      長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 唾液腺腫瘍WHO分類2017・新規の組織型を理解する 導管内癌の疾患概念と診断2018

    • Author(s)
      中黒 匡人, 長尾 俊孝
    • Organizer
      日本病理学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 膵頭十二指腸切除術を機にmultiple endocrine neoplasia type 1の確定診断に至った一例2018

    • Author(s)
      杉浦 圭治, 上野 真, 大久保 諒, 長尾 佳奈, 二階堂 靖訓, 眞島 孝聡, 山口 浩, 長尾 俊孝
    • Organizer
      日本病理学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 淡明細胞リッチな頬粘膜唾液腺癌(Clear cell-rich salivary gland carcinoma of the buccal mucosa)2018

    • Author(s)
      星野 都, 井上 勝元, 井上 ハルミ, 菊池 建太郎, 山内 雅司, 坂下 英明, 佐藤 由紀子, 竹内 賢吾, 長尾 俊孝, 草間 薫
    • Organizer
      日本病理学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 頭頸部腫瘍新WHO国際分類について 唾液腺腫瘍と歯原性腫瘍を中心に 唾液腺腫瘍2017WHO分類 改訂のポイント2018

    • Author(s)
      長尾 俊孝
    • Organizer
      日本病理学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 唾液腺癌に対するニボルマブの早期治療効果と安全性の検討2018

    • Author(s)
      丹羽 一友, 多田 雄一郎, 岡本 伊作, 岡崎 雅, 増淵 達夫, 伏見 千宙, 岡田 拓朗, 馬場 大輔, 三浦 弘規, 長尾 俊孝, 塚原 清彰, 五月女 隆
    • Organizer
      日本唾液腺学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 唾液腺上皮筋上皮癌にはHRAS遺伝子変異が高率かつ特異的に認められる2018

    • Author(s)
      中黒 匡人, 浦野 誠, 平井 秀明, 谷川 真希, 多田 雄一郎, 塚原 清彰, 長尾 俊孝
    • Organizer
      日本唾液腺学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 耳下腺腫瘍の新たな治療戦略 耳下腺癌の病理診断 最近の進歩2018

    • Author(s)
      長尾 俊孝
    • Organizer
      日本唾液腺学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 異型カルチノイドの細胞学的検討2018

    • Author(s)
      石原 里佳子, 松林 純, 三宅 真司, 小池 悦子, 前田 純一, 垣花 昌俊, 梶原 直尚, 大平 達夫, 池田 徳彦, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 平成28年度 施設認定年報報告からのデータ解析2018

    • Author(s)
      佐々木 伸也, 若狹 朋子, 棟方 哲, 亀井 敏昭, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 末梢性小型肺野病変に対する術中捺印細胞診細胞像の検討2018

    • Author(s)
      垣花 昌俊, 前田 純一, 松林 純, 三宅 真司, 大平 達夫, 梶原 直央, 筒井 英光, 河手 典彦, 長尾 俊孝, 池田 徳彦
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 多核巨細胞を多数伴った耳下腺肉腫の1例2018

    • Author(s)
      青野 卓矢, 有田 茂実, 酒井 えり, 高橋 司, 板倉 朋恵, 小高 亜紀子, 竹山 裕之, 杉山 孝弘, 伊丹 真紀子, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 節外性低悪性度B細胞リンパ腫に対する穿刺吸引細胞診の有用性と限界 涙腺・唾液腺における低悪性度リンパ腫(MALTリンパ腫)に対する細胞診の有用性2018

    • Author(s)
      渡部 顕章, 三宅 真司, 谷川 真希, 小池 悦子, 高橋 礼典, 山口 浩, 原 由紀子, 松林 純, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] Tumor-like lesions of salivary glands2017

    • Author(s)
      Toshitaka Nagao
    • Organizer
      10th APIAP
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 肺転移をきたした耳下腺筋上皮癌の1例2017

    • Author(s)
      渡部 顕章, 松林 純, 小池 悦子, 三宅 真司, 稲垣 敦史, 川内 ゆうか, 金子 清花, 忽滑谷 昌平, 平井 秀明, 高橋 礼典, 垣花 昌俊, 梶原 直央, 大平 達夫, 池田 徳彦, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 唾液腺腫瘍の細胞診:新WHO分類を踏まえて 唾液腺分泌癌の細胞学的特徴と鑑別診断2017

    • Author(s)
      浦野 誠, 樋口 佳代子, 宮部 悟, 長尾 俊孝, 黒田 誠
    • Organizer
      日本臨床細胞学会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 唾液腺腫瘍の細胞診:新WHO分類を踏まえて 唾液腺腫瘍新WHO分類の解説2017

    • Author(s)
      長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 浸潤性増殖を示した口蓋再発性多形腺腫の1例2017

    • Author(s)
      小川 郁子, 宮坂 知佳, 石田 光明, 藤澤 琢郎, 井原 遥, 長尾 俊孝, 高田 隆
    • Organizer
      日本唾液腺学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 基底細胞腺腫と基底細胞腺癌はbeta-cateninの発現とCTNNB1遺伝子の変異を伴う2017

    • Author(s)
      中黒 匡人, 浦野 誠, 長尾 俊孝
    • Organizer
      日本唾液腺学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 唾液腺腫瘍新WHO国際分類の解説2017

    • Author(s)
      長尾 俊孝
    • Organizer
      日本唾液腺学会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 腺様嚢胞癌との鑑別に苦慮した耳下腺基底細胞腺癌の1例2017

    • Author(s)
      忽滑谷 昌平, 三宅 真司, 小池 悦子, 稲垣 敦史, 山口 真由実, 川内 ゆうか, 金子 清花, 原 由紀子, 松林 純, 長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 耳下腺原発リンパ上皮癌の1例2017

    • Author(s)
      桑原 淳, 片桐 仁子, 渡部 顕章, 藤井 愛子, 鈴木 恵美子, 石原 里佳子, 五百部 浩昭, 三宅 真司, 平井 秀明, 長尾 俊孝
    • Organizer
      日本唾液腺学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 細胞診とIgG4関連疾患 有用性と限界 涙腺・唾液腺におけるIgG4関連疾患の病理と細胞診2017

    • Author(s)
      長尾 俊孝
    • Organizer
      日本臨床細胞学会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 改めて見直す唾液腺腫瘍における免疫染色の実践的な臨床病理学的意義 唾液腺腫瘍の病理診断と治療の観点から見たHER2とAR染色の意義2017

    • Author(s)
      平井 秀明, 多田 雄一郎, 長尾 俊孝
    • Organizer
      日本病理学会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 改めて見直す唾液腺腫瘍における免疫染色の実践的な臨床病理学的意義 唾液腺腫瘍病理診断における汎用マーカーS-100蛋白の有用性とピットフォール2017

    • Author(s)
      中黒 匡人, 長尾 俊孝
    • Organizer
      日本病理学会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 唾液腺導管癌ではFOXA1の発現が予後予測因子となる2017

    • Author(s)
      平井 秀明, 多田 雄一郎, 川北 大介, 志村 智隆, 塚原 清彰, 加納 里志, 小澤 宏之, 大上 研二, 佐藤 雄一郎, 長尾 俊孝
    • Organizer
      日本病理学会
    • Related Report
      2017 Research-status Report
  • [Book] 外科病理学 第5版2020

    • Author(s)
      長尾 俊孝
    • Total Pages
      1892
    • Publisher
      文光堂
    • Related Report
      2019 Annual Research Report
  • [Book] 免疫染色化学 実践的な診断・治療方針決定のために 第3部 3.唾液腺2020

    • Author(s)
      中黒 匡人、長尾 俊孝
    • Total Pages
      460
    • Publisher
      文光堂
    • Related Report
      2019 Annual Research Report
  • [Book] 病理と臨床 今月の話題 唾液腺腫瘍における遺伝子異常と病理診断2020

    • Author(s)
      中黒 匡人、長尾 俊孝
    • Total Pages
      100
    • Publisher
      文光堂
    • Related Report
      2019 Annual Research Report
  • [Book] 免疫染色究極マニュアル 第1版,5 唾液腺2019

    • Author(s)
      中黒 匡人、長尾 俊孝(編:伊藤 智雄)
    • Total Pages
      368
    • Publisher
      金芳堂
    • Related Report
      2019 Annual Research Report
  • [Book] 癌診療指針のための病理診断プラクティス 唾液腺/口腔・歯原性腫瘍2019

    • Author(s)
      長尾 俊孝
    • Total Pages
      400
    • Publisher
      中山書店
    • Related Report
      2019 Annual Research Report
  • [Book] 病理組織の見方と鑑別診断2018

    • Author(s)
      赤木忠厚、松原修、真鍋俊明、吉野正、小田義直、長尾俊孝
    • Total Pages
      699
    • Publisher
      医歯薬出版
    • ISBN
      9784263731857
    • Related Report
      2018 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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