| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Outline of Final Research Achievements |
To establish rapid serodiagnosis for amebiasis, we developed a fluorescence immunochromatography kit using fluorescent silica nanoparticles coated with a recombinant fragment of Entamoeba histolytica-specific surface protein (C-Igl). The kit was evaluated by using sera from patients with amebiasis and other infectious diseases in Japan and Thailand. The study confirmed that the assay has an acceptable level of sensitivity and specificity. In addition, the use of a fluorescence scope was effective for distinguishing between positive and negative results.
|
