| Project/Area Number |
17K09086
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Ehime University |
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Principal Investigator |
Furukawa Shinya 愛媛大学, 医学系研究科, 寄附講座准教授 (60444733)
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| Co-Investigator(Kenkyū-buntansha) |
三宅 吉博 愛媛大学, 医学系研究科, 教授 (50330246)
田中 景子 愛媛大学, 医学系研究科, 准教授 (40341432)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 睡眠 / 細小血管障害 / 糖尿病 / 合併症 |
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| Outline of Final Research Achievements |
We conducted an epidemiological study on the association between night life behavior / sleep status and diabetic complications in Japanese patients with type 2 diabetes. In this study, 297 patients were enrolled. Data on shift work, diet before sleep, sleep time, erectile dysfunction, etc. were obtained using a questionnaire. Diabetic specialist assessed diabetic complications (microangiopathy and macroangiopathy). Through this study, we were able to construct a database that can evaluate diabetic complications based on nighttime activities and sleep situations.
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| Academic Significance and Societal Importance of the Research Achievements |
糖尿病の治療については食事療法、運動療法に加えて薬物療法が基本とされている。しかし、過去の糖尿病の発症や合併症に対して睡眠時間がU字カーブの関連性を持ったり、夜間排尿回数がさまざまな疾患発症との関連がすでに指摘されている。一方で、国民の睡眠への関心は非常に高く、本研究の解析によって糖尿病と睡眠との関連や睡眠に関連する夜間の行動様式に関するエビデンスが構築できると考えられる。
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