Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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Outline of Final Research Achievements |
There is no therapy for choroidal atrophy, one of the leading causes of blindness in Japan. We investigated whether transplantation of retinal pigment epithelium (RPE) and vascular endothelial cells (HUVEC) regenerate the choroidal atrophy. A HUVEC adhered to the human iPS-RPE cell sheet was produced by co-culture. Although we transplanted the HUVEC-adhered iPS-RPE cell sheet to choroidal atrophy in rabbit, choroidal regeneration was not obtained.
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