| Project/Area Number |
17K16913
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Osaka University |
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Principal Investigator |
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| Research Collaborator |
OGAWA MAKOTO
HOSOKAWA KIYOHITO
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| Project Period (FY) |
2017-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 声門閉鎖 / 電気声門図 / 高速度撮影装置 / 咳払い / 音声障害 / 発声 / 声門閉鎖の間接的評価 / 喉頭科学 / 解析・評価 |
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| Outline of Final Research Achievements |
In the present study, we applied EGG for investigating the glottal closure condition during cough, and aimed to identify the laryngeal motion reflected by a transient EGG prominence observed at the beginning of cough motion, and to assess whether or not the presence of an EGG prominence predicted the cough efficiency in unilateral vocal fold paralysis patients (UVFP). The present study demonstrated that a transient EGG prominence during cough reflected the contact between the bilateral vocal folds just before the compression phase of cough, and that the presence of a transient EGG prominence was related to the cough efficiency. These results suggest that a transient EGG prominence may be a superior useful sign for predicting a vocal fold closure ability to fiberscopic findings, particularly in UVFP patients without a clear laryngeal view.
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| Academic Significance and Societal Importance of the Research Achievements |
近年、音声障害は医療・社会的ニーズが高まっている疾患である。音声酷使あるいは頻回の咳払いなどの問題行動が音声障害の発症に関与することはよく知られている。本研究では高速度撮影装置とEGGの同期記録システムを用いて、咳払いにおけるEGG波形の一過性上昇が声帯突起の接触を反映し、そのEGG波形の一過性上昇の有無は高い一致率で評価できることを証明した。この結果より、発声や咳払い時の声帯間接触の頻度および程度の定量的評価法を確立することで、従来不明であった声の使用に関する問題行動と喉頭組織への障害、音声障害発症との因果関係を解明できる可能性がある。
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