• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Temporal and spatial regulation of signal transduction by Rab family small G proteins

Research Project

Project/Area Number 18390089
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field General medical chemistry
Research InstitutionThe University of Tokushima

Principal Investigator

SASAKI Takuya  The University of Tokushima, Institute of Health Biosciences, Graduate School, Professor (40241278)

Project Period (FY) 2006 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥16,030,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2007: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2006: ¥10,700,000 (Direct Cost: ¥10,700,000)
KeywordsSignal transduction / Rab proteins / neurotransmission / cell-cell adhesion / cell growth / Rab3A / Rab12 / Rab7 / Rabファミリー低分子量G蛋自質 / JRAB / タイトジャンクション / アドヘレンスジャンクション / Rab3 GAP
Research Abstract

The Rab family small G proteins, which consist of more than 60 different members in mammalian cells, are key regulators in membrane trafficking. Since each member recognizes distinct subsets on intracellular membranes, this family may contribute to temporal and spatial regulation of signal transduction in various cellular functions. In this project, we analyzed the functions of Rab proteins in neurotransmission, cell-cell adhesion, and cell growth. As to neurotransmission, we focused on the process of neurotransmitter release, which Rab3A and its related proteins regulate. We generated Rab3 GAP p130-deficient mice and showed using the mice that this protein plays important roles in neurotransmitter release and synaptic plasticity through regulation of the activity and translocation of Rab3A at the nerve endings. As to the cell-cell adhesion, we focused on the transport of the adhesion proteins to the cell-cell adhesion sites of the epithelial cells. We had previously found that Rabl3 regulates the transport of the integral adhesion proteins, claudins and occludin, to the tight junctions. In this project, we identified JRAB/MICAL-L2 as a novel Rabl3 effector protein, which localized to the tight junctions and found that the Rab13-JRAB system functions to establish the formation of the tight junctions. We moreover found that another Rab family member Rab8 also interacts with JRAB and that this interaction contributes to the assembly of adherens junctions through regulation of the transport of E-cadherin, an integral adherens junction protein. As to the cell growth, we showed that Rabring7, which we had identified as a novel Rab7 effector protein, has E3 ligase activity and that this protein is involved in the endocytic trafficking of EGF receptor through its E3 ligase activity.

Report

(3 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • Research Products

    (64 results)

All 2008 2007 2006 Other

All Journal Article (41 results) (of which Peer Reviewed: 18 results) Presentation (23 results)

  • [Journal Article] The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.2008

    • Author(s)
      Yamamura, R.
    • Journal Title

      Mol. Biol. Cell 19

      Pages: 971-983

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Doc2α and Munc13-4 regulate Ca^<2+->dependent secretory lysosome exocytosis in mast cells.2008

    • Author(s)
      Higashio, H.
    • Journal Title

      J. Immunol. 180

      Pages: 4774-4784

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Involvement of Rab13 and JRAB/MICAL-L2 in epithelial cell scattering.2008

    • Author(s)
      Kanda, I.
    • Journal Title

      Oncogene 27

      Pages: 1687-1695

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell -cell junctions and the formation of functional tight junctions.2008

    • Author(s)
      Nakatsuji, H.
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 3324-3335

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Interaction of Rab3B with microtubule-binding protein Gas8 in NIH 3T3 cells.2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      Arch. Biochem. Biophys. 474

      Pages: 136-142

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Rab family small G proteins in regulation of epithelial apical junctions.2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      Front. Biosci. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Cell-surface biotinylation to study endocytosis and recycling of occludin.2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      Methods Mol. Biol. 440

      Pages: 89-96

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Regulation of epithelial cell adhesion and repulsion: role of endocytic recycling.2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      J. Med. Invest. 55

      Pages: 9-16

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Analysis on the emerging role of Rab3 GTPase-activating protein in Warburg Micro and Martsolf syndrome.2008

    • Author(s)
      Sakane, A.
    • Journal Title

      Methods Enzymol. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Identification and characterization of JRAB/MICAL-L2, a junctional Rab 13-binding protein.2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      Methods Enzymol. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The interaction of JRAB/MICAL-L2 with RabS and Rabl3 coordinates the assembly of tight junctions and adherens junctions2008

    • Author(s)
      Yamamura, R., et. al.
    • Journal Title

      Mol. Biol. Cell 19

      Pages: 971-983

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Doc2a and Munc13-4 regulate Ca2 -dependent secretory lysosome exocytosis in mast cells2008

    • Author(s)
      Higashio, H., et. al.
    • Journal Title

      J. Immunol 180

      Pages: 4774-4784

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Involvement of Rabl3 and JRAB/MICAL-L2 in epithelial cell scattering2008

    • Author(s)
      Kanda, I., et. al.
    • Journal Title

      Oncogene 27

      Pages: 1687-1695

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions2008

    • Author(s)
      Nakatsuji, H., et. al.
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 3324-3335

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Interaction of Rab3B with microtubule-binding protein GasS in NIH 3T3 cells2008

    • Author(s)
      Nishimura, N., et. al.
    • Journal Title

      Arch. Biochem. Biophys 474

      Pages: 136-142

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Cell-surface biotinylation to study endocytosis and recycling of occludin2008

    • Author(s)
      Nishimura, N., et. al.
    • Journal Title

      Methods Mol. Biol 440

      Pages: 89-96

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Regulation of epithelial cell adhesion and repulsion : role of endocytic recycling2008

    • Author(s)
      Nishimura, N., et. al.
    • Journal Title

      J. Med. Invest 55

      Pages: 9-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Analysis on the emerging role of Rab3 GTPase-activating protein in Warburg Micro and Martsolf syndrome2008

    • Author(s)
      Sakane, A., et. al.
    • Journal Title

      Methods Enzymol 438

      Pages: 131-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Identification and characterization of JRAB/MICAL-L2, a junctional Rab13-binding protein2008

    • Author(s)
      Nishimura, N., et. al.
    • Journal Title

      Methods Enzymol 438

      Pages: 141-153

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens functions2008

    • Author(s)
      Yamamura, R.
    • Journal Title

      Mol.Biol.Cell 19

      Pages: 971-983

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Doc2α and Munc13-4 regulate Ca^<2+>-dependent secretory lysosome exocytosis inmast cells2008

    • Author(s)
      Higashio, H.
    • Journal Title

      J. Immunol. 180

      Pages: 4774-4784

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of Rab13 and JRAB/MICAL-L2 in epithelial cell scattering2008

    • Author(s)
      Kanda, I.
    • Journal Title

      Oncoeene 27

      Pages: 1687-1695

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of Actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-celljunctions and the formation of functional tight junctions2008

    • Author(s)
      Nakatsuji, H.
    • Journal Title

      Mol.Cell.Biol. (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction of Rab3B with microtubule-binding protein Gas8 in NIH 3T3 cells2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      Arch. Biochem. Biophys. (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rab family small G proteins in regulation of epithelial apical junctions2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      Front.Biosci. (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cell-surface biotinylation to study endocytosis and recycling of occludin2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      Methods Mol.Biol. 440

      Pages: 89-96

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Regulation of epithelial cell adhesion and repulsion:role of endocytic recycling2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      J. Med. Invest. 55

      Pages: 9-16

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis on the emerging role of Rab3 GTPase-activating protein in Warburg Micro and Martsolf syndrome2008

    • Author(s)
      Sakane, A.
    • Journal Title

      Methods Enzymol. (in press)

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Identification and characterization of JRAB/MICAL-L2, a junctional Rab13-binding protein2008

    • Author(s)
      Nishimura, N.
    • Journal Title

      Methods Enzymol. (in press)

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Involvement of Rabring7 in EGF receptor degradation as an E3 ligase.2007

    • Author(s)
      Sakane, A.
    • Journal Title

      Biochem. Biophys. Res. Commun. 357

      Pages: 1058-1064

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Involvement of Rabring7 in EGF receptor degradation as an E3 ligase2007

    • Author(s)
      Sakane, A., et. al.
    • Journal Title

      Biochem. Biophys. Res. Commun 357

      Pages: 1058-1064

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Involvement of Rabring7 in EGF receptor degradation as an E3 ligase2007

    • Author(s)
      Sakane, A.
    • Journal Title

      Biochem.Biophys.Rea.Commun. 357

      Pages: 1058-1064

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of Rabring7 in EGF receptor degradation as an E3 ligase2007

    • Author(s)
      Sakane, A.
    • Journal Title

      Biochem.Biophys.Res.Commun. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Cell-surface biothinylation to study endocytosis and recycling of occludin2007

    • Author(s)
      Nishimura, N.
    • Journal Title

      Methods Mol.Biol. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin.2006

    • Author(s)
      Terai, T.
    • Journal Title

      Mol. Biol. Cell 17

      Pages: 2465-2475

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Rab3 GTP ase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab32006

    • Author(s)
      Sakane, A.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 10029-10034

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin2006

    • Author(s)
      Terai, T., et. al.
    • Journal Title

      Mol. Biol. Cell 17

      Pages: 2465-2475

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab32006

    • Author(s)
      Sakane, A., et. al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 10029-10034

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin2006

    • Author(s)
      Terai, T.
    • Journal Title

      Mol.Biol.Cell 17

      Pages: 2465-2475

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Rab3 GTPase-activating proteinz regulates synaptic transmission and plasticity through the inactivation of Rab32006

    • Author(s)
      Sakane, A.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 103

      Pages: 10029-10034

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Rab family small G proteins in regulation of epithelial apical junctions

    • Author(s)
      Nishimura, N., et. al.
    • Journal Title

      Front. Biosci (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] マスト細胞の調節性分泌におけるDoc2α-Munc13-4系の役割2007

    • Author(s)
      東尾 浩典
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-13
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Involvement of the Doc2a-Munc13-4 system in Ca^<2+>-dependent mast cell exocytosis2007

    • Author(s)
      Higashio, H., et. al.
    • Organizer
      The 30th Annual Meeting of the Molecular Biology Society of Japan・The 80th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      in Yokohama
    • Year and Date
      2007-12-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Rab13結合蛋白質JRAB/MICAL-12とactinin-4による上皮細胞極性化の制御機構2007

    • Author(s)
      西村 範行
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Involvement of JRAB/MICAL-L2 and actinin-4 in the regulation of epithelial polarization2007

    • Author(s)
      Nishimura, N., et. al.
    • Organizer
      The 30th Annual Meeting of the Molecular Biology Society of Japan・The 80th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      in Yokohama
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Functions of Rab family small G proteins in regulated exocytosis.2007

    • Author(s)
      Takuya Sasaki
    • Organizer
      International Symposium on Membrane Traffic
    • Place of Presentation
      Awaji
    • Year and Date
      2007-11-29
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Functions of Rab family small G proteins in regulated exocytosis2007

    • Author(s)
      Sasaki, T., et. al.
    • Organizer
      International Symposium on Membrane Traffic
    • Place of Presentation
      in Awaji
    • Year and Date
      2007-11-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Actinin-4によるJRAB/MICAL-L2の細胞膜局在の制御機構.2007

    • Author(s)
      中逵 弘能
    • Organizer
      第66回癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] タイトジャンクションとアドヘレンスジャンクションの形成におけるJRAB/MICAL-L2とRab8/13の役割2007

    • Author(s)
      山村 里恵
    • Organizer
      第66回癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to the plasma membrane2007

    • Author(s)
      Nakatsuji, H., et. al.
    • Organizer
      The 66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      in Yokohama
    • Year and Date
      2007-10-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Role of JRAB/MICAL-L2 interaction with Rab8 and Rab13 in the assembly of tight junction and adherens junction2007

    • Author(s)
      Yamamura, R., et. al.
    • Organizer
      The 66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      in Yokohama
    • Year and Date
      2007-10-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Functions of Rab family small G proteins in regulated exocytosis2007

    • Author(s)
      Takuya Sasaki
    • Organizer
      International Symposium on Membrane Traffic
    • Place of Presentation
      Awaji
    • Year and Date
      2007-09-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] Rab3低分子量G蛋白質ファミリーによる視床下部-下垂体-性腺系の制御2007

    • Author(s)
      坂根 亜由子
    • Organizer
      第80回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-15
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Regulation of hormone secretion on the hypothalamus-pituitary-ovary axis by Rab family small G proteins2007

    • Author(s)
      Sakane, A., et. al.
    • Organizer
      The 80th JES Scientific Meeting Tokyo
    • Place of Presentation
      in Tokyo
    • Year and Date
      2007-06-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] JRAB/MICAL-L2の細胞膜局在におけるactinin-4の役割2007

    • Author(s)
      中逵 弘能
    • Organizer
      第59回日本細胞生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2007-05-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] JRAB/MICAL-L2とRab8/13によるタイトジャンクションとアドヘレンスジャンクションの制御機構2007

    • Author(s)
      山村 里恵
    • Organizer
      第59回日本細胞生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2007-05-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] マスト細胞の調節性分泌におけるDoc2の役割.2007

    • Author(s)
      東尾 浩典
    • Organizer
      第59回日本細胞生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2007-05-30
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Actinin-4 is involved in the recruitment of JRAB/MICAL-L2 to the plasma membrane2007

    • Author(s)
      Nakatsuji, H., et. al.
    • Organizer
      The 59 th Annual Meeting of the Japan Society for Cell Bioloty
    • Place of Presentation
      in Fukuoka
    • Year and Date
      2007-05-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions2007

    • Author(s)
      Yamamura, R., et. al.
    • Organizer
      The 59 th Annual Meeting of the Japan Society for Cell Bioloty
    • Place of Presentation
      in Fukuoka
    • Year and Date
      2007-05-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Doc2a modulates secretory lysosome exocytosis in mast cells2007

    • Author(s)
      Higashio, H., et. al.
    • Organizer
      The 59 th Annual Meeting of the Japan Society for Cell Bioloty
    • Place of Presentation
      in Fukuoka
    • Year and Date
      2007-05-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Rab13結合蛋白質JRABによるタイトジャンクション形成の制御機構2006

    • Author(s)
      西村 範行
    • Organizer
      第65回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 上皮細胞の細胞分散(cell scattering)におけるRab13-JRAB系の役割2006

    • Author(s)
      神田 郁乃
    • Organizer
      第65回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Role of Rabl3 and JRAB (a junctional Rab13-binding protein) in epithelial cell scattering2006

    • Author(s)
      Kanda, I., et. al.
    • Organizer
      The 65th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      in Yokohama
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] JRAB (a junctional Rab 13-binding protein : regulates the assembly of tight junction2006

    • Author(s)
      Nishimura, N., et. al.
    • Organizer
      he 65th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      in Yokohama
    • Year and Date
      2006-09-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi