Impact of zinc nutrient status on acquirement of antibody and prevalence of infectious disease among Vietnamese infants

• Project/Area Number: 18406027
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: Public health/Health science
• Research Institution: Ochanomizu University
• Principal Investigator: YAMAMOTO Shigeru Ochanomizu University, 大学院・人間文化創成科学研究科, 教授 (70093896)
• Co-Investigator(Kenkyū-buntansha): NAKAMORI Masayo お茶の水女子大学, 生活化学部, アソシエイトフェロー (40380034) ; 酒井 徹 大阪府立大学, 総合リハビリテーション学部, 准教授 (40274196) ; 武田 憲明 (武田 憲昭) 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (30206982) ; 吉池 信男 独立行政法人国立・栄養研究所, 栄養調査研究部, 部長 (80240232)
• Co-Investigator(Renkei-kenkyūsha): SAKAI Tohru 大阪府立大学, 総合リハビリテーション学部, 教授 (40274196) ; TAKEDA Noriaki 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (30206982) ; YOSHIIKE Nobuo (独)国立健康・栄養研究所, 国際産学連携センター, 研究員 (80240232)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥15,680,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥2,280,000); Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2007: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000); Fiscal Year 2006: ¥5,800,000 (Direct Cost: ¥5,800,000)
• Keywords: 栄養学 / 感染症 / 社会医学 / 国際協力

Research Abstract

本研究は、亜鉛の栄養状態が子どもの成長や、予防接種(麻疹)による免疫の獲得を含めた感染症の罹患に与える影響について検討することを目的とした。ベトナム北西部Bac Giang省YenThe地区を代表する4村において、6ヶ月齢～2歳の乳幼児とその母親を対象とし、乳幼児の亜鉛の栄養状態、母乳および離乳食からの亜鉛摂取状況、成長発達、予防接種後の麻疹抗体価および感染症の発症について調査を実施し、栄養介入を今後実施するために有益な知見を得た。

Research Products

• [Journal Article] Nutritional status, feeding practice and incidence of infectious diseases among children aged 6 to 18 months in northern mountainous Vietnam (2010)
  • Author(s): Nakamori M, Ninh NX, Khan NC, Huong CT, Tuan NA, Mai LB, Hien VTT, Nhung BT, Nakano T, Yoshiike N, Kusama K, Yamamoto S.
  • Journal Title: J Med Invest 57 Pages: 45-53
  • NAID: 130004465200
• [Journal Article] Preliminary research on the nutrient status and breast milk concentration of iron, zinc and cupper in lactating mothers at 6 to 12 month of postpartum in rural Vietnam. (2009)
  • Author(s): Nakamori M, Ninh NX, Isomura H, Yoshiike N, Hien VTT, Nhug BT, Nhien NV, Nakano T, Khan NC, Yamamoto S.
  • Journal Title: J Nutr Sci Vitaminol 55 (4) Pages: 338-345
• [Journal Article] Preliminary research on the nutrient status and breast milk concentration of iron, zinc and cupper in lactating mothers at 6 to 12 month of postpartum in rural Vietnam (2009)
  • Author(s): Nakamori M, Ninh NX, Isomura H, Yoshiike N, Hien VTT, Nhug BT, Nhien NV, Nakano T, Khan NC, Yamamoto S.
  • Journal Title: J Nutr Sci Vitaminol 55(4)
  • Peer Reviewed
• [Journal Article] Ratio of low serum zinc levels in elderly Japanese people living in the central part of Japan (2007)
  • Author(s): Kogirima M, Kurasawa R, Kubori S, Sarukura N, Nakamori M, Okada S, Kamioka H, Yamamoto S.
  • Journal Title: Eur J Clin Nutr 61(3) Pages: 375-81
• [Journal Article] Ratio of low serum zinc levels in elderly Japanese people living in the central part of Japan. (2007)
  • Author(s): Kogirma M, Kurasawa R, Kubori S, Sarukura N, Nakamori M, Okada S, Kamioka, Yamamoto S
  • Journal Title: EJCN 61 Pages: 375-381
• [Journal Article] Zinc nutrition in healthy subjects and patients with taste impairment from the view point of zinc ingestion, serum zinc concentration and angiotensin converting enzyme activity (2006)
  • Author(s): Ueda C, Takaoka T, Sarukura N, Matsuda K, Kitamura Y, Toda N, Tanaka T, Yamamoto S, Takeda N.
  • Journal Title: Auris Nasus Larynx 33 (3) Pages: 283-8
• [Journal Article] Increased nerve growth factor by zinc supplementation with concurrent vitamin A deficiency does not improve memory performance in mice. (2006)
  • Author(s): Kheirvari S, Uezu K, Sakai T, Nakamori M, Alizadeh M, Sarukura N, Yamamoto S.
  • Journal Title: J Nutr Sci Vitaminol 52 (6) Pages: 421-7
  • NAID: 110006152267
• [Journal Article] Increased nerve growth factor by zinc supplementation with concurrent vitamin A deficiency does not improve memory performance in mice. (2006)
  • Author(s): Kheirvari S, Uezu K, Sakai T, Nakamori M, Alizadeh M, Sarukura N, Yamamoto S.
  • Journal Title: J Nutr Sci Vitaminol 52(6) Pages: 421-7
  • NAID: 110006152267
• [Journal Article] Zinc nutrition in healthy subjects and patients with taste impairment from the view point of zinc ingestion, serum zinc concentration and angiotensin converting enzyme activity. (2006)
  • Author(s): Ueda C, Takaoka T, Sarukura N, Matsuda K, Kitamura Y, Toda N, Tanaka T, Yamamoto S, Takeda N.
  • Journal Title: Auris Nasus Larynx 33(3) Pages: 283-8
• [Presentation] ベトナム山岳地域における授乳婦の母乳濃度 (鉄・亜鉛) と栄養状態に関する調査 (2008)
  • Author(s): 中森正代, Nguyen Xuan Ninh, Nguyen Cong Khan, 磯村晴彦, Vu Thi Thu Hien, Bui Thi Nhung, 中野貴司, 吉池信男, 山本茂
  • Organizer: 第49回日本熱帯医学会大会・第23回日本国際保健医療学会学術集会 合同大会
  • Place of Presentation: 東京都、東京
• [Presentation] ベトナム山岳地域における授乳婦の母乳濃度(鉄・亜鉛)と栄養状態に関する調査 (2008)
  • Author(s): 中森正代, Nguyen Xuan Ninh, Nguyen Cong Khan, 磯村晴彦, Vu Thi Thu Hien, Bui Thi Nhung, 中野貴司, 吉池信男, 山本茂
  • Organizer: 第49回日本熱帯医学会大会・第23回日本国際保健医療学会学衛集会合同大会
  • Place of Presentation: 東京都、東京
• [Presentation] ベトナム山岳地域における完全母乳保育実施状況と乳幼児の成長発達、感染症の罹患 (2007)
  • Author(s): 中森正代, Nguyen Xuan Ninh, Nguyen Cong Khan, Cao thu Huong, Le Bac Mai, Vu Thi Thu Hien, 中野貴司, 吉池信男, 草間かおる, 山本茂
  • Organizer: 第22回日本国際保健医療学会全国総会
  • Place of Presentation: 吹田市、大阪