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Brain science of emotion and stress response

Research Project

Project/Area Number 18500203
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Cognitive science
Research InstitutionNagoya University

Principal Investigator

IIDAKA Tetsuya  Nagoya University, 大学院・医学系研究科, 准教授 (70324366)

Co-Investigator(Kenkyū-buntansha) SADATO Norihiro  生理学研究所, 大脳皮質機能研究系, 教授 (00273003)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥4,230,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥630,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2007: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2006: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywords顔認知 / 遺伝子多型 / セロトニン / 灰白質 / 多文化研究 / 拡散テンソル画像 / 機能的磁気共鳴画像 / 脳賦活検査 / 扁桃体 / DTI
Research Abstract

健常者におけるストレス刺激への反応性を、機能的磁気共鳴画像(fMRI)と脳賦活検査を用いて研究した。顔刺激と不快な音声刺激を組み合わせ、新奇な嫌悪条件づけ課題を作成してfMRI実験を行った。学習に伴う扁桃体の反応が、一過性に上昇することが分かった。この結果は日常的な視覚と聴覚刺激によって、扁桃体を介した嫌悪条件づけが行われることを示している。日本人が日本人の笑顔を見ている時の脳活動を計測し、後部帯状回が同じ人種の表情認知に関わっていることを発表した。その他にMRIによって計測された扁桃体の体積と、気質の1つである損害回避傾向が関連していることを示した。

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (16 results)

All 2008 2007 2006 Other

All Journal Article (8 results) (of which Peer Reviewed: 3 results) Presentation (4 results) Book (2 results) Remarks (2 results)

  • [Journal Article] Neural correlates involved in processing happy affect on same race faces2008

    • Author(s)
      Iidaka T, Nogawa J, Kansaku K, Sadato N
    • Journal Title

      Journal of Psychophysiology 22

      Pages: 91-99

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 特集/fMRIと精神医学fMRIでみる精神疾患の中間表現型2008

    • Author(s)
      飯高哲也
    • Journal Title

      臨床精神医学 37

      Pages: 805-810

    • Related Report
      2008 Final Research Report
  • [Journal Article] 扁桃体-情動脳と社会脳扁桃体のニューロイメージング2008

    • Author(s)
      飯高哲也
    • Journal Title

      Clinical Neuroscience 26

      Pages: 431-434

    • Related Report
      2008 Final Research Report
  • [Journal Article] 特集/fMRIと精神医学 fMRIでみる精神疾患の中間表現型2008

    • Author(s)
      飯高哲也
    • Journal Title

      臨床精神医学 37

      Pages: 805-810

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 扁桃体-情動脳と社会脳 扁桃体のニューロイメージング2008

    • Author(s)
      飯高哲也
    • Journal Title

      Clinical Neuroscience 26

      Pages: 431-434

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Neural correlates involved in processing happy affect on same race faces.2008

    • Author(s)
      Iidaka T, Nogawa J, Kansaku K, Sadato N
    • Journal Title

      Journal of Psychophysiology (in press)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Volume of left amygdala subregion predicted temperamental trait of harm avoidance in female young subjects2006

    • Author(s)
      Iidaka T, Matsumoto A, Ozaki N, Suzuki T, Iwata N, Yamamoto Y, Okada T, Sadato N
    • Journal Title

      A voxel-based morphometry study 1125

      Pages: 85-93

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Volume of left amygdala subregion predicted temperamental trait of harm avoidance in female young subjects. A voxel-based morphometry study2006

    • Author(s)
      Iidaka T, Matsumoto A, et al.
    • Journal Title

      Brain Research 1125

      Pages: 85-93

    • Related Report
      2006 Annual Research Report
  • [Presentation] Neural responses in the amygdala and hippocampus relate with extinction of aversive face and voice stimuli2008

    • Author(s)
      Iidaka T, Saito D, Komeda H, Mano Y, Ozaki N, Sadato N
    • Organizer
      14th Annual Meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2008-06-18
    • Related Report
      2008 Final Research Report
  • [Presentation] Neural responses in the amygdala and hippocampus relate with extinction of aversive face and voice stimuli2008

    • Author(s)
      Iidaka T, Saito D, Komeda H, Mano Y, et al
    • Organizer
      14th Annual Meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      オーストラリア、メルボルン
    • Year and Date
      2008-06-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Integrity of the right cingulum is related to sustained attention as measured by Diffusion Tensor Imaging and Continuous Performance Test in normal subjects2007

    • Author(s)
      Takahashi M, Iidaka T, Iwamoto K, Fukatsu H, Naganawa S, Ozaki N
    • Organizer
      13th Annual Meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2007-06-13
    • Related Report
      2008 Final Research Report
  • [Presentation] Integrity of the right cingulum is related to sustained attention as measured by Diffusion Tensor Imaging and Continuous Performance Test in normal subjects.2007

    • Author(s)
      Takahashi M, Iidaka T, Iwamoto K, Fukatsu H, Naganawa S, Ozaki N
    • Organizer
      13th Annual Meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      シカゴ 米国
    • Year and Date
      2007-06-13
    • Related Report
      2007 Annual Research Report
  • [Book] 「精神疾患の脳画像解析・診断学」II 脳画像検査から病態を探る B. 機能的変化が表すもの 編集 平安良雄, 笠井清澄2008

    • Author(s)
      飯高哲也
    • Publisher
      南山堂
    • Related Report
      2008 Final Research Report
  • [Book] 「精神疾患の脳画像解析・診断学」編集 : 平安良雄, 笠井清澄II. 脳画像検査から病態を探る B. 機能的変化が表すもの2008

    • Author(s)
      飯高哲也
    • Publisher
      南山堂
    • Related Report
      2008 Annual Research Report
  • [Remarks] (1) フジテレビ アンビリーバボー顔認知メカニズム2008年4月24日放映

    • Related Report
      2008 Final Research Report
  • [Remarks] (2) 朝日新聞 心をのぞく「性格の遺伝要因複雑」2008年4月10日版

    • Related Report
      2008 Final Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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