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Establishment of the standard degree of oral function classified by age.

Research Project

Project/Area Number 18592292
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionTsurumi University

Principal Investigator

RYO Koufuchi  Tsurumi University, School of Dental Medicine, Assistant professor (10298268)

Co-Investigator(Kenkyū-buntansha) SAITO Ichiro  Tsurumi university, School of Dental Medicine, professor (60147634)
MORITO Mitsuhiko  Tsurumi university, School of Dental Medicine, professor (30089429)
MISHIMA Kenji  Tsurumi university, School of Dental Medicine, Assistant professor (50275343)
INOUE Hiroko  Tsurumi university, School of Dental Medicine, Assistant professor (50367306)
Project Period (FY) 2006 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥3,880,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥480,000)
Fiscal Year 2007: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2006: ¥1,800,000 (Direct Cost: ¥1,800,000)
KeywordsAnti-aging / aging / saliva / teeth / occlusal force / oxidative stress / Candida / hormone / 骨密度 / 筋力 / CPI
Research Abstract

Background : Along with the life expectancy increasing, the concern with oral function has been growing. That is the reason why impaired oral function may play one of the important roles in elderly with relationship of degradation of Quality of Life, sign and symptoms of age-related diseases. However, it is difficult to diagnose oral function because that is determined a complex functional organ. For this reason, although studies have been made on partly analysis classified by age, there is little agreement on age-related change.
Method: We selected 8 methods optionally from prior studies that suggested age-related change of a part of oral function, the number of teeth, Community Periodontal Index (CPI), bite force, unstimulated saliva flow rate, stimulated saliva flow rate, evaluation of oral Candidiasis and Repetitive Saliva Swallowing Test (RSST): We evaluated these methods and the quality of life for 285 participants age from 22 to 90, and outcomes were submitted to a statistic evaluation (T test of Student) in order to analyze any possible significant differences (p<0.05).
Results: All results of 8 methods show significant age-related change (p<0.05). By subjective appearance, Low rate of saliva flow have a serious influence upon decline of the quality of life.
Conclusions : This study fixed the standard degree of total oral function classified by age. And there is considerable validity in these methods to diagnose aging of oral function.

Report

(3 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • Research Products

    (44 results)

All 2008 2007 2006

All Journal Article (7 results) (of which Peer Reviewed: 1 results) Presentation (23 results) Book (14 results)

  • [Journal Article] 加齢による変化とそのアンチエイジング:口腔2007

    • Author(s)
      梁 洪淵
    • Journal Title

      Journal of Otolaryngology, Head and Neck Surgery 23

      Pages: 1563-1567

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 歯科医療のためのアンチエイジング2007

    • Author(s)
      斎藤一郎 他
    • Journal Title

      歯科医療 21.1

      Pages: 4-59

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Possible involvement of oxidative stress in salivary gland of patients with Sjogren's syndrome2006

    • Author(s)
      Koufuchi, Ryo
    • Journal Title

      Pathobiology 73

      Pages: 252-260

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Possible involvement of oxidative stress in salivary patients with Sjogren's syndrome.2006

    • Author(s)
      Koufuchi Ryo.
    • Journal Title

      Pathobiology 73

      Pages: 252-260

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Possible involvement of oxidative stress in salivary gland of patients with Sjogren's syndrome2006

    • Author(s)
      Koufuchi Ryo, Ichiro Saito et al.
    • Journal Title

      Pathobiology 73.5

      Pages: 252-260

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 口腔から考えるアンチエイジング2006

    • Author(s)
      梁 洪淵, 斎藤一郎
    • Journal Title

      Meedical Science Digest 32.5

      Pages: 20-23

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 歯科医からのアンチエイジングアドバイス2006

    • Author(s)
      梁 洪淵, 斎藤一郎
    • Journal Title

      Modern Physician 26.4

      Pages: 581-584

    • Related Report
      2006 Annual Research Report
  • [Presentation] Effects of Coenzyme Q10 gum administration on xerostomia.2008

    • Author(s)
      Kazumune Arikawa, et. al.
    • Organizer
      Japanese Society Anti-Aging Medicine
    • Year and Date
      2008-05-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] CoenzymeQ10の唾液分泌に対する効果の検討2007

    • Author(s)
      梁 洪淵
    • Organizer
      第7回日本抗加齢医学会
    • Place of Presentation
      京都
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 歯科用アマルガム充填症例の毛髪検査による水銀汚染の検討2007

    • Author(s)
      梁 洪淵
    • Organizer
      第7回日本抗加齢医学会
    • Place of Presentation
      京都
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 口腔と全身の老化度測定の検討2007

    • Author(s)
      徳永 淳二
    • Organizer
      第7回日本抗加齢医学会
    • Place of Presentation
      京都
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 口腔の老化度評価における基準値の検討2007

    • Author(s)
      徳永 淳二
    • Organizer
      第7回日本抗加齢医学会
    • Place of Presentation
      京都
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of Coenzyme Q10 administration on xerostomia.2007

    • Author(s)
      Koufuchi Ryo, et. al.
    • Organizer
      Japanese Society Anti-Aging Medicine
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Correlation between mercury concentrations in hair and dental amalgam fillings.2007

    • Author(s)
      Koufuchi Ryo, et. al.
    • Organizer
      Japanese Society Anti-Aging Medicine
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Establishment of oral and body classified by age.2007

    • Author(s)
      Junji Tokunaga, et. al.
    • Organizer
      Japanese Society Anti-Aging Medicine
    • Year and Date
      2007-07-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] CoenzymeQ10の唾液分泌に対する効果の検討2007

    • Author(s)
      梁 洪淵
    • Organizer
      第7回日本抗加齢医学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2007-07-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] 歯科用アマルガム充填症例の毛髪検査による水銀汚染の検討2007

    • Author(s)
      梁 洪淵
    • Organizer
      第7回日本抗加齢医学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2007-07-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] 口腔と全身の老化度測定の検討2007

    • Author(s)
      徳永淳二
    • Organizer
      第7回日本抗加齢医学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2007-07-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] 口腔の老化度評価における基準値の検討2007

    • Author(s)
      徳永淳二
    • Organizer
      第7回日本抗加齢医学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2007-07-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] シェーグレン症候群における酸化ストレスを介した腺組織障害機序の解析2007

    • Author(s)
      梁 洪淵
    • Organizer
      第44回日本消化器免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2007-07-09
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Possible involvement of oxidative stress in salivary patients with Sjogren's syndrome.2007

    • Author(s)
      Koufuchi Ryo, et. al.
    • Organizer
      The Japanese Society for Mucosal
    • Year and Date
      2007-07-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Establishment of the standard degree of oral function classified by age.2007

    • Author(s)
      Junji Tokunaga, et. al.
    • Organizer
      Japanese Society Anti-Aging Medicine
    • Year and Date
      2007-05-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of super oxide dismutase of xerostomia.2007

    • Author(s)
      Yoshinori Tai, et. al.
    • Organizer
      Japanese Society Anti-Aging Medicine
    • Year and Date
      2007-05-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Possible involvement of oxidative stress in salivary patients with Sjogren's syndrome.2007

    • Author(s)
      Hiroyuki Yamada, et. al.
    • Organizer
      Japanese Society Anti-Aging Medicine
    • Year and Date
      2007-05-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] コエンザイムQ10によるドライマウス改善の試み2007

    • Author(s)
      梁 洪淵
    • Organizer
      第4回日本コエンザイムQ10協会研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-02-02
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effects of Coenzyme Q10 administration on xerostomia.2007

    • Author(s)
      Koufuchi Ryo, et. al.
    • Organizer
      Japanese Coenzyme Q Association
    • Year and Date
      2007-02-02
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Coenzyme Q10含有ガムによる唾液分泌効果の臨床研究2006

    • Author(s)
      有川 量崇
    • Organizer
      第6回日本抗加齢医学会
    • Place of Presentation
      東京
    • Year and Date
      2006-05-20
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 口腔の老化度評価の検討2006

    • Author(s)
      徳永 淳二
    • Organizer
      第6回日本抗加齢医学会
    • Place of Presentation
      東京
    • Year and Date
      2006-05-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] SODによる酸化スイレスを介した外分泌機能障害に対する予防効果2006

    • Author(s)
      田井 良憲
    • Organizer
      第6回日本抗加齢医学会
    • Place of Presentation
      東京
    • Year and Date
      2006-05-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 唾液腺分泌障害における酸化ストレス度の検討2006

    • Author(s)
      山田 浩之
    • Organizer
      第6回日本抗加齢医学会
    • Place of Presentation
      東京
    • Year and Date
      2006-05-19
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 現代生活における口腔の健康の重要性2008

    • Author(s)
      梁 洪淵
    • Publisher
      保健指導ハンドブック
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 保健指導ハンドブック2008

    • Author(s)
      梁 洪淵・斎藤一郎
    • Publisher
      社会保険研究所
    • Related Report
      2007 Annual Research Report
  • [Book] アンチエイジング医学、アンチエイジングドックの理論と実践 口腔の年齢2007

    • Author(s)
      梁 洪淵(共著)
    • Publisher
      診断と治療社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] アンチエイジング医学、エイジングによる疾患-口腔の老化-2007

    • Author(s)
      梁 洪淵(共著)
    • Publisher
      診断と治療社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 加齢による変化とそのアンチエイジング-口腔-2007

    • Author(s)
      梁 洪淵
    • Publisher
      東京医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 3.アンチエイジング医学の検査アンチエイジング医学の検査1)全身のアンチエジング検査-2007

    • Author(s)
      梁 洪淵
    • Publisher
      第一歯科出版
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 歯科医療のためのアンチエイジング医学の基礎と臨床-5.対処法4)有害金属-2007

    • Author(s)
      梁 洪淵
    • Publisher
      第一歯科出版
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] アンチエイジング医学入門2007

    • Author(s)
      梁 洪淵
    • Total Pages
      95
    • Publisher
      永末書店
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 歯科医師・歯科衛生士のためのアンチエイジング医学入門2007

    • Author(s)
      斎藤一郎 編著
    • Total Pages
      95
    • Publisher
      永末書店
    • Related Report
      2006 Annual Research Report
  • [Book] アンチエイジングドック2007

    • Author(s)
      吉川敏一 編集
    • Total Pages
      129
    • Publisher
      診断と治療社
    • Related Report
      2006 Annual Research Report
  • [Book] 口腔から考えるアンチエイジング2006

    • Author(s)
      梁 洪淵
    • Publisher
      ニューサイエンス社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] 抗加齢医療-歯科からのアンチエイジング・アドバイス-2006

    • Author(s)
      梁 洪淵
    • Publisher
      新興医学出版
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Book] アンチエイジング医学2006

    • Author(s)
      吉川敏一 編集
    • Total Pages
      267
    • Publisher
      診断と治療社
    • Related Report
      2006 Annual Research Report
  • [Book] 口腔から実践するアンチエイジング医学2006

    • Author(s)
      斎藤一郎 編著
    • Total Pages
      259
    • Publisher
      永末書店
    • Related Report
      2006 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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