A study on the emergent mechanism of neuronal circuits for memory formation by simultaneous fMRI and EEG

• Project/Area Number: 18680027
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Cognitive science
• Research Institution: Kyoto University (2007-2008); Okayama University (2006)
• Principal Investigator: MIZUHARA Hiroaki Kyoto University, 大学院・情報学研究科, 講師 (30392137)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥23,270,000 (Direct Cost: ¥17,900,000、Indirect Cost: ¥5,370,000); Fiscal Year 2008: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2007: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000); Fiscal Year 2006: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
• Keywords: 神経科学 / 脳・神経 / 認知科学 / 計測工学 / 生物・生体工学 / 非侵襲脳活動計測 / 脳波 / MRI / 機能的MRI / 脳機能イメージング / θ波 / 記憶処理過程 / 注意 / 前頭葉 / 海馬

Research Abstract

脳内の神経回路網は, 状況に応じて動的に形成される必要がある. しかしながら, 従来の脳機能イメージング手法では, この動的に形成される神経回路網を同定することが困難であった. そこで本研究では, 脳波と機能的磁気共鳴画像法を同時に計測することにより, 脳内で動的に創発する皮質ネットワークを同定する手法を構築した. さらに, 記憶化大中の脳波と機能的磁気共鳴画像法の同時計測を実施することにより, 記憶保持に関連して動的に生成される脳内のネットワークを同定した.

Research Products

• [Journal Article] 神経ダイナミクスと知能創発 (2009)
  • Author(s): 水原啓暁
  • Journal Title: 計測と制御 48 Pages: 94-99
  • NAID: 10024756508
• [Journal Article] Human cortical circuits for central executive function emerge by theta phase synchronization. (2007)
  • Author(s): Hiroaki Mizuhara, Yoko Yamaguchi
  • Journal Title: NeuroImage Vol. 36 Pages: 232-244
  • Peer Reviewed
• [Journal Article] Human cortical circuits for central executive function emerge by theta phase synchronization (2007)
  • Author(s): Hiroaki Mizuhara, Yoko Yamaguchi
  • Journal Title: NeuroImage 36 Pages: 232-244
  • Peer Reviewed
• [Journal Article] Human cortical circuits for central executive function emerge by theta phase synchronization (2007)
  • Author(s): Hiroaki Mizuhara, Yoko Yamaguchi
  • Journal Title: Neurolmage 予定(確約あり)
• [Presentation] 脳波位相同期による動的な皮質ネットワーク形成 (2008)
  • Author(s): 水原啓暁
  • Organizer: 日本認知科学会「パターン認識と知覚モデル研究分科会」
  • Place of Presentation: 金沢
  • Year and Date: 2008-07-28
• [Presentation] EEG theta-gamma coupling during explicit memory retention (2008)
  • Author(s): Mizuhara, H. and Yamaguchi, Y.
  • Organizer: Human Brain Mapping, 14th Annual Meeting
  • Place of Presentation: Melbourne, Austraria
  • Year and Date: 2008-06-16
• [Presentation] 新規風景の記憶保持中に創発する脳波θ-γ協調 (2008)
  • Author(s): 水原啓暁, 山口陽子
  • Organizer: 日本認知心理学会第6回大会
  • Place of Presentation: 千葉
  • Year and Date: 2008-05-13
• [Presentation] EEG theta-gamma coupling during explicit memory retention. (2008)
  • Author(s): Mizuhara, H., and Yamaguchi, Y.
  • Organizer: Human Brain Mapping, 14th Annual Meeting
  • Place of Presentation: Melbourne, Austraria
• [Presentation] Neuronal networks with theta and gamma oscillations for encoding novel events in attentional blink task. (2007)
  • Author(s): Mizuhara H., Yamaguchi Y
  • Organizer: Society for Neuroscience, 37th annual meeting
  • Place of Presentation: SanDiego, USA
  • Year and Date: 2007-11-04
• [Presentation] Theta EEG power enhancement for encoding novel scene at attentional blink period. (2007)
  • Author(s): Mizuhara H., and Yamaguchi Y
  • Organizer: Neuro2007, The 30th annual meeting of Japan Neuroscience Society
  • Place of Presentation: Yokohama.
• [Presentation] Neuronal networks with theta and gamma oscillations for encoding novel events in attentional blink task. (2007)
  • Author(s): Mizuhara H., and Yamaguchi Y.
  • Organizer: Society for Neuroscience, 37th annual meeting
  • Place of Presentation: San Diego
• [Remarks] 受賞 : Hiroaki Mizuhara, Yoko Yamaguchi, Human cortical circuits for central executive function emerge by theta phase synchronization, NeuroImage Section Editors Choice Award, (2007.6)