Screening of endogenous factors modulating regularly occurring feeding behavior in the silkworm, Bombyx mori

• Project/Area Number: 18780083
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Bioproduction chemistry/Bioorganic chemistry
• Research Institution: The University of Tokyo
• Principal Investigator: NAGATA Shinji The University of Tokyo, 大学院農学生命科学研究科, 助教 (40345179)
• Project Period (FY): 2006 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥3,960,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥360,000); Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000); Fiscal Year 2006: ¥1,300,000 (Direct Cost: ¥1,300,000)
• Keywords: 昆虫 / 摂食行動 / カイコ / ペプチド / 摂食周期 / HemaP / p4442 / 脂肪体 / LC-MS / LC-TOF-MS / 脂肪細胞 / レポーターアッセイ

Research Abstract

昆虫の摂食行動に関わる生体内分子の探索を行なった結果、カイコ(Bombyx mori)の幼虫から新規のペプチド性因子を2 つ見出すことができた。ともに機能は未知であるが、脂肪体で発現し体液中に分泌するペプチドであり摂食行動や栄養要求に関連することが示唆された。

Research Products

• [Journal Article] (2009)
  • Author(s): 永田晋治、諸岡信克、松本澄洋、長澤寛道
  • Journal Title: Ann. NY. Aca. Sci. Trends in Endocrinol. Neurobiol. 1163 Pages: 481-483
• [Journal Article] Characterization of feeding-delaying factors from the silkworm, Bombyx mori (2009)
  • Author(s): 永田晋治、諸岡信克、松本澄洋、長澤寛道
  • Journal Title: Ann. N. Y. Acad. Sci. Trends in Endocrinology and Neurobiology (印刷中)
  • Peer Reviewed
• [Journal Article] A convenient method for preparation of biologically active recombinant CHH of the kuruma prawn, Marsupenaeus japonicus, using the bacterial expression system (2009)
  • Author(s): 永井千晶、浅妻英章、永田晋治、大平剛、長澤寛道
  • Journal Title: Peptides 30 Pages: 507-517
  • NAID: 10020188473
  • Peer Reviewed
• [Journal Article] (2008)
  • Author(s): 永田晋治、伯野史彦、高橋伸一郎、長澤寛道
  • Journal Title: Comp. Biochem. Physiol. B 151 Pages: 355-360
• [Journal Article] (2008)
  • Author(s): 永田晋治
  • Journal Title: 化学と生物 46 Pages: 420-426
• [Journal Article] Identification of Bombyx mori Akt and its phosphorylation by bombyxin stimulation (2008)
  • Author(s): 永田晋治、伯野史彦、高橋伸一郎、長澤寛道
  • Journal Title: Comp. Biochem. Physiol. B 151 Pages: 355-360
  • Peer Reviewed
• [Journal Article] 昆虫の摂食行動の分子メカニズム (2008)
  • Author(s): 永田晋治
  • Journal Title: 化学と生物 46 Pages: 420-426
• [Journal Article] Molecular cloning and expression analysis of ecdysone receptor and retinoid X receptor from the kuruma prawn, Marsupenaeus japonicus. (2007)
  • Author(s): 浅妻英章、永田晋治、河野美智子、長澤寛道
  • Journal Title: Comp. Biochem. Physiol. B 148 Pages: 139-150
  • Peer Reviewed
• [Journal Article] (2006)
  • Author(s): 永田晋治、長澤寛道
  • Journal Title: J. Insect Physiol. 52 Pages: 807-815
• [Journal Article] (2006)
  • Author(s): 永田晋治、大森幸枝、長澤寛道
  • Journal Title: Biosci. Biotech. Biochem. 70 Pages: 554-558
• [Journal Article] Effects of diet-deprivation and physical stimulation on the feeding behaviour of the larvae of the silkworm, Bombyx mori. (2006)
  • Author(s): 永田晋治, 長澤寛道
  • Journal Title: Journal of Insect Physiology 52 Pages: 807-815
• [Journal Article] Dietary sterol preference in the silkworm, Bombyx mori. (2006)
  • Author(s): 永田晋治, 大森幸枝, 長澤寛道
  • Journal Title: Bioscience Biotechnology Biochemistry 70 Pages: 3094-3098
  • NAID: 10018524420
• [Journal Article] A novel type of receptor cDNA from the prothoracic glands of the silkworm, Bombyx mori. (2006)
  • Author(s): 永田晋治, 並木俊樹, 黄憐恵, 片岡宏誌, 鈴木昭憲
  • Journal Title: Bioscience Biotechnology Biochemistry 70 Pages: 554-558
  • NAID: 10018534791
• [Presentation] (2009)
  • Author(s): 永田晋治、諸岡信克、長澤寛道
  • Organizer: 日本農芸化学会
  • Place of Presentation: 福岡
• [Presentation] (2009)
  • Author(s): 諸岡信克、永田晋治、長澤寛道
  • Organizer: 日本農芸化学会
  • Place of Presentation: 福岡
• [Presentation] (2009)
  • Author(s): 松本澄洋、永田晋治、諸岡信克、長澤寛道
  • Organizer: 日本農芸化学会
  • Place of Presentation: 福岡
• [Presentation] (2009)
  • Author(s): 小沼貴裕、諸岡信克、永田晋治、長澤寛道
  • Organizer: 日本農芸化学会
  • Place of Presentation: 福岡
• [Presentation] 昆虫の摂食行動モチベーションの分子動態 (2008)
  • Author(s): 永田晋治
  • Organizer: 日本比較内分泌学会
  • Place of Presentation: 広島大学
  • Year and Date: 2008-12-05
• [Presentation] Characterization of feeding-delaying factors from the silkworm, Bombyx mori (2008)
  • Author(s): 永田晋治、諸岡信克、松本澄洋、長澤寛道
  • Organizer: 24th Conference European Comparative Endocrinologists
  • Place of Presentation: ジェノバ、イタリア
  • Year and Date: 2008-09-04
• [Presentation] カイコ幼虫の摂食行動調節因子HemaPの体内変動解析 (2008)
  • Author(s): 永田晋治、長澤寛道
  • Organizer: 日本農芸化学会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-03-27
• [Presentation] エビガラスズメの摂食行動調節因子HemaPの0結合型糖鎖の構造解析 (2008)
  • Author(s): 諸岡信克、永田晋治、白井孝治、木口憲爾、長澤寛道
  • Organizer: 日本農芸化学会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-03-27
• [Presentation] カイコBombyx moriの摂食行動調節因子HemaPの体内変動 (2008)
  • Author(s): 永田晋治、長澤寛道
  • Organizer: 日本蚕糸学会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-03-21
• [Presentation] 鱗翅目の摂食行動調節因子HemaPの構造解析 (2008)
  • Author(s): 諸岡信克、永田晋治、白井孝治、木口憲爾、嶋田透、長澤寛道
  • Organizer: 日本蚕糸学会
  • Place of Presentation: 名古屋
  • Year and Date: 2008-03-21
• [Presentation] (2008)
  • Author(s): 永田晋治、諸岡信克、松本澄洋、長澤寛道
  • Organizer: 24th Conference European Comparative Endocrinologists
  • Place of Presentation: Genova, Italy
• [Presentation] (2008)
  • Author(s): 永田晋治
  • Organizer: 日本比較内分泌学会(招待講演)
  • Place of Presentation: 広島大学
• [Presentation] (2008)
  • Author(s): 諸岡信克、永田晋治、白井孝治、木口憲爾、長澤寛道
  • Organizer: 日本比較内分泌学会
  • Place of Presentation: 広島大学
• [Presentation] (2008)
  • Author(s): 永田晋治、大森幸枝、酒井芙美、長澤寛道
  • Organizer: 日本分子生物学会
  • Place of Presentation: 神戸
• [Presentation] 新規ペプチドp4442の餌中のステロールによる発現変動 (2007)
  • Author(s): 永田晋治、大森幸枝、酒井芙美、長澤寛道
  • Organizer: 日本分子生物学会
  • Place of Presentation: 横浜
  • Year and Date: 2007-12-04
• [Presentation] A novel peptide, p4442, from Bombyx mori larval hemolymph senses the excess sterol diet (2007)
  • Author(s): 永田晋治、大森幸枝、酒井芙美、長澤寛道
  • Organizer: 4th APACE(国際化学生態学会)
  • Place of Presentation: つくば(国際会議場エポカルつくば)
  • Year and Date: 2007-07-10
• [Presentation] (2007)
  • Author(s): 永田晋治、大森幸枝、酒井芙美、長澤寛道
  • Organizer: 4th APACE(国際化学生態学会)
  • Place of Presentation: Tsukuba, Japan
• [Book] ホルモンハンドブック(分担執筆) (2007)
  • Publisher: 南江堂