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高分解能EISTとアルブミン輸送モデルによる早期リンパ浮腫診断法と予測法の確立

Research Project

Project/Area Number 18F18060
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeSingle-year Grants
Section外国
Research Field Fluid engineering
Research InstitutionChiba University
Host Researcher 武居 昌宏  千葉大学, 大学院工学研究院, 教授 (90277385)
Foreign Research Fellow BAIDILLAH MARLIN  千葉大学, 工学(系)研究科(研究院), 外国人特別研究員
Project Period (FY) 2018-04-25 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2019: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2018: ¥1,200,000 (Direct Cost: ¥1,200,000)
KeywordsElectrical Impedance / random noise / image reconstruction / contact impedance / tomography / Lymphedema / Subcutaneous adipose tissue / long-term monitoring / electrically / equivalent / phantom
Outline of Annual Research Achievements

c-EIST system and the prediction model of Lymphedema through the proposal of Albumin Transport Model (ATM) are very important and highly needed. However, the research of c-EIST development for Lymphedema detection was quite tough because of we lack real data from patient. Thus, it is needed more data from the clinical trial. The knowledge on our team about the development this system and prediction model, obviously can be applied on wide research area. On this study, variations of albumin concentration on fluid plasma and saline-agar phantom as a mimic of SAT were conducted because it is not established yet. It shows that the increasing the albumin concentration causes the decreasing of the resistance plasma serum in the case of globulin protein is considered as confounding factor (Baidillah, et a., 2018a). In the case of sensor attached to the object surface, the contact impedance arise and affect to the unknown impedance measurement. This study has proposed a new method to eliminate the unknown contact impedance by employing the cole-cole impedance model (Baidillah, et al., 2019a). It is obvious to conclude that the changing of impedance measurement due to increasing of albumin content level is smaller as compared with one due to the time-varying random noise. Elimination the effect of time-varying random noise is also proposed to improve the performance (Baidillah, et al., 2019b). Moreover, we proposed a method to improve the image reconstruction algorithm method in order to evaluate the changing of SAT on the long-term monitoring (Ryoma, et al., 2020).

Research Progress Status

令和元年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和元年度が最終年度であるため、記入しない。

Report

(2 results)
  • 2019 Annual Research Report
  • 2018 Annual Research Report

Research Products

(9 results)

All 2020 2019 2018

All Journal Article (3 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results,  Open Access: 2 results) Presentation (6 results) (of which Int'l Joint Research: 6 results)

  • [Journal Article] Investigation of physiological swelling on conductivity distribution in lower leg subcutaneous tissue by electrical impedance tomography2020

    • Author(s)
      Ryoma Ogawa, Marlin Ramadhan Baidillah, Shinsuke Akita, Masahiro Takei
    • Journal Title

      Journal of Electrical Bioimpedance

      Volume: 11 Pages: 1-7

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Compensation of volatile-distributed current due to variance of the unknown contact impedance in an electrical impedance tomography sensor2019

    • Author(s)
      Baidillah Marlin Ramadhan、Kawashima Daisuke、Takei Masahiro
    • Journal Title

      Measurement Science and Technology

      Volume: 30 Pages: 034002-034002

    • DOI

      10.1088/1361-6501/aafb22

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Adaptive Noise Cancellation Algorithms Implemented onto FPGA-Based Electrical Impedance Tomography System2019

    • Author(s)
      Marlin Ramadhan Baidillah, Zengfeng Gao, Al-Amin S Iman, Masahiro
    • Journal Title

      Electrical Science & Engineering

      Volume: 01(20) Pages: 15-25

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] A 2-D CFD Model of Albumin-rich-fluid distribution in human subcutaneous tissue for early stage of Lymphedema Prediction2019

    • Author(s)
      Dharma IA, Baidillah MR, Sugawara M, Takei M
    • Organizer
      10th Int’l Conference on Thermofluid
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Protein resistivity imaging by electrical impedance tomography for betimes diagnosis of unilateral lymphedema2019

    • Author(s)
      Sifuna MW, Baidillah MR, Yanagisawa R, Jeon M, Darma PN and Takei M
    • Organizer
      The 4rd 4th Africa International Biotechnology and Biomedical Conference (AIBBC), 26-27 August 2019, Mombasa, Kenya
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Adipose Tissue Area Assessment by Means Electrical Impedance Tomography towards the Lymphedema Detection2018

    • Author(s)
      Marlin R Baidillah, P N Darma, R Yanagisawa, R Ogawa, M Takei
    • Organizer
      8th Annual Meeting of International Lymphoedema Framework Japan
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Compensation for the unknown contact impedance variance using frequency-difference electrical impedance spectro-tomography2018

    • Author(s)
      Marlin R Baidillah, Martin W Sifuna, & Masahiro Takei
    • Organizer
      9th World Congress in Industrial Process Tomography (WCIPT9)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] FPGA Implementation of LMS and NLMS Adaptive filters for Electrical Impedance Tomography System2018

    • Author(s)
      Al Amin S Iman, Marlin R Baidillah, & Masahiro Takei
    • Organizer
      9th World Congress in Industrial Process Tomography (WCIPT9)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of EIT for Lymphedema diagnostic2018

    • Author(s)
      Yanagisawa, R., Baidillah, M.R., Iman, A. S., & Takei, M.
    • Organizer
      The 57th Annual Conference of Japanese Society for Medical and Biological Engineering
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research

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Published: 2018-05-01   Modified: 2021-01-27  

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