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Development of stimulus-responsive cellulose nanocrystals based on terminal functionalization method and its biomedical application

Research Project

Project/Area Number 18F18090
Research Category

Grant-in-Aid for JSPS Fellows

Allocation TypeSingle-year Grants
Section外国
Research Field Wood science
Research InstitutionKyoto University
Host Researcher 上高原 浩  京都大学, 農学研究科, 教授 (10293911)
Foreign Research Fellow DHAR PRODYUT  京都大学, (連合)農学研究科(研究院), 外国人特別研究員
Project Period (FY) 2018-10-12 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2020: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 2019: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2018: ¥1,100,000 (Direct Cost: ¥1,100,000)
KeywordsCellulose nanocrystals / Transparent Wood / Microfluidics / Biomedical / Nanomotors
Outline of Annual Research Achievements

The microfluidic device was fabricated for continuous production of Cellulose Nanocrystals (CNCs) on silica wafers through lithography techniques with three different designs of T-shape, Y-shape, and concentric circles. The efficiency of the device was analyzed by passing the acid solutions and cellulose suspension require for CNC production. In second project, we developed functionalized nanocellulose (NC) based composites using plant-derived and microbial source through sustainable and greener routes for their potential application as high-performance composites. The main aim of the project is to utilize different types of such waste lignin derivatives such as alkali lignin (AL) and chemically modified cationic lignin (Catlig) as a precursor to NC bioprocessing. This work demonstrates a unique approach of utilizing lignin, as a smart additive to in situ BC fermentation in which it concurrently acts as a promoter to microbial growth as well as reinforcing filler for fabrication of multifunctional composites. In third project, we have used Hinoki wood in our research and have developed a novel approach for production of delignified wood (DW) with the retention of their interesting multi-scale hierarchical micro-architecture. Further, a strategic chemical modification of DW has been carried out to develop transparent wood, which finds potential applications in different sectors have been applied for patent.

Research Progress Status

令和2年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和2年度が最終年度であるため、記入しない。

Report

(3 results)
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report

Research Products

(3 results)

All 2021 2019 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (1 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results) Remarks (1 results)

  • [Journal Article] Synthesis-property-performance relationships of multifunctional bacterial cellulose composites fermented in situ alkali lignin medium2021

    • Author(s)
      Dhar Prodyut、Sugimura Kazuki、Yoshioka Mariko、Yoshinaga Arata、Kamitakahara Hiroshi
    • Journal Title

      Carbohydrate Polymers

      Volume: 252 Pages: 117114-117114

    • DOI

      10.1016/j.carbpol.2020.117114

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Presentation] Studies on Functionalization of Cellulose Nanocrystals for Development of Polymeric Bionanocomposites and Applications in Sustainable Chemical Processes2019

    • Author(s)
      Prodyut Dhar
    • Organizer
      257th ACS National Meeting & Exposition
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Remarks] 京都大学大学院農学研究科森林科学専攻複合材料化学分野

    • URL

      https://fukugou.kais.kyoto-u.ac.jp/

    • Related Report
      2020 Annual Research Report

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Published: 2018-10-15   Modified: 2022-03-04  

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