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Mechanics of walled biological cells explored with macroscale physical models

Research Project

Project/Area Number 18H01192
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 13040:Biophysics, chemical physics and soft matter physics-related
Research InstitutionRitsumeikan University

Principal Investigator

WADA Hirofumi  立命館大学, 理工学部, 教授 (50456753)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2021: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2020: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2019: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2018: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Keywords弾性シェル / 座屈不安定性 / バイオメカニクス / 形態力学 / マクロ模型実験 / スナップフィット / 幾何学的な剛性 / 細胞の構造力学 / シェルの弾性論 / 細菌の細胞骨格 / スケールアップ模型
Outline of Final Research Achievements

In this research project, we have investigated mechanics and geometry of a range of thin structures including rods, ribbons, plates and cylindrical shells by combining physical experiments, numerical simulations and analytical theory. The project aimed at obtaining mechanical insights onto the structures and functions of walled biological cells such as bacteria and plant cells. While we were less successful at revealing effects of large turgor pressure on such stiff walled cells, we were able to obtain the major results in the five inter-related projects, the details of which are described separately in this final report.

Academic Significance and Societal Importance of the Research Achievements

本研究課題の主題は、バクテリアや植物細胞の生物学的機能を支える力学的構造についての理解を深めることであった。力学的側面に着目する限り、類似の構造を有するもっと巨視的でありふれた対象を深く調べることには大きな意義がある。本研究では、円筒型の弾性シェルの変形に始まり、弾性リボン、折り紙や切り紙、そしてスナップフィットのような工業デザインの力学的仕組みまで、多岐にわたる系の新たな性質をいくつも明らかにした。これらの成果は、親しみやすい系への我々の理解を直接的に促進しただけでなく、細胞壁をもつ生物の力学デザインを明らかにするための概念的基盤を提供するものである。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • Research Products

    (10 results)

All 2022 2020 2019 2018

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 3 results) Presentation (2 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results) Book (1 results) Funded Workshop (1 results)

  • [Journal Article] Structure, Design, and Mechanics of a Pop-Up Origami with Cuts2022

    • Author(s)
      Yoneda Taiju、Miyamoto Yoshinobu、Wada Hirofumi
    • Journal Title

      Physical Review Applied

      Volume: 17 Issue: 2 Pages: 1-6

    • DOI

      10.1103/physrevapplied.17.l021004

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mechanics of a Snap Fit2020

    • Author(s)
      Keisuke Yoshida and Hirofumi Wada
    • Journal Title

      Physical Review Letters

      Volume: 125 Issue: 19 Pages: 194301-194301

    • DOI

      10.1103/physrevlett.125.194301

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Structure, design, and mechanics of a paper spring2019

    • Author(s)
      Taiju Yoneda, Daichi Matsumoto and Hirofumi Wada
    • Journal Title

      Physical Review E

      Volume: 100 Issue: 1 Pages: 013003-013003

    • DOI

      10.1103/physreve.100.013003

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] しなやかさとともにかたちあり --弾性と幾何2019

    • Author(s)
      佐野友彦 和田浩史
    • Journal Title

      日本物理学会誌

      Volume: 74 Pages: 822-829

    • NAID

      130007843280

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Twist-induced snapping in a bent elastic rod and ribbon2019

    • Author(s)
      Tomohiko G. Sano and Hirofumi Wada
    • Journal Title

      Physical Review Letters

      Volume: 122 Issue: 11 Pages: 114301-114301

    • DOI

      10.1103/physrevlett.122.114301

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pinching an open cylindrical shell: Extended deformation and its persistence2018

    • Author(s)
      Daichi Matsumoto, Tomohiko G. Sano, and Hirofumi Wada
    • Journal Title

      EPL (Europhysics Letters)

      Volume: 123 Issue: 1 Pages: 14001-14001

    • DOI

      10.1209/0295-5075/123/14001

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Presentation] からくりおもちゃパタパタ(ヤコブの梯子)の力学模型2019

    • Author(s)
      和田浩史
    • Organizer
      日本物理学会 2019年秋季大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] A snapping ribbon, cone, and cylinder2019

    • Author(s)
      Hirofumi Wada
    • Organizer
      GFS follow on: Mathematics of form in active and inactive media
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Book] Plant Biomechanics ("Twsiting Growth in Plant Roots"の章を執筆)2018

    • Author(s)
      Hirofumi Wada and Daichi Matsumoto
    • Total Pages
      441
    • Publisher
      Springer
    • ISBN
      9783319790985
    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] APEF20182018

    • Related Report
      2018 Annual Research Report

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Published: 2018-04-23   Modified: 2023-01-30  

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